Causes And Risk Factors Of Miscarriages
Numerous underlying factors can cause miscarriages. In some cases, the exact causes might be left unknown, however, understanding what causes miscarriages is crucial for preventing and treating future pregnancies. The most common causes generally involve genetic or chromosomal abnormalities, maternal health conditions, environmental factors, and lifestyle choices. Read the following points to understand what may cause a miscarriage:
- Incompetent cervix (your cervix begins to open too early in pregnancy)
- Exposure to TORCH diseases
- Severe kidney disease
- Congenital heart disease
- Diabetes that isn't managed
- Thyroid disease
- Radiation
- Certain medicines, such as the acne drug isotretinoin (Accutane®)
- Severe malnutrition
- Lifestyle choices including smoking, drinking alcohol, having excessive caffeine, and consuming narcotics can increase the risk of miscarriage.
Chromosomal Abnormalities
Around 50% of miscarriages that occur in the first trimester are due to chromosomal abnormalities. If there is an error in the structure and number of the chromosomes during conception, it leads to improper fetal development. These abnormalities occur randomly and cannot be predicted. However, these issues are more common in geriatric pregnancies, especially those over the age of 35.
Every developing fetus gets a pair of chromosomes from its father and mother. The chromosomal abnormalities are as follows.
- Trisomy: It occurs when there is an extra chromosome in a set. The most common chromosomal abnormality is Trisomy21 which can cause Down syndrome.
- Monosomy: It happens when a chromosome is missing from a set.
- Triploidy: When an embryo has three complete sets of chromosomes instead of two, it results in 69 chromosomes instead of the normal 46 chromosomes.
- Translocations: Translocations refer to broken chromosomes attached to other chromosomes. It leads to a structural abnormality that may cause a miscarriage.
Usually, these abnormalities occur during cell division, during the formation of an egg, or early fetal development.
Other Risk Factors
Apart from these genetic issues, other risk factors of miscarriages also include chronic health conditions like uncontrolled diabetes, high blood pressure, autoimmune problems, and thyroid disorders.
Bad lifestyle choices like smoking, drinking, and drug use can also lead to pregnancy loss in the early stages. Additionally, exposure to environmental toxins can be a major cause of miscarriage.
Unchecked stress, hormonal imbalance, and physical trauma can impact the healthy growth of your fetus. So, managing these risk factors can also help you overcome unexpected miscarriages.