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Written By Veda Maddala , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy
Last Updated Jan 1, 2025 | 2:45 PM IST
Zofer Injection 4 ml is an antiemetic medication used in the treatmnet and prevention of nausea and vomiting during chemotherapy. This medication contains ondansetron which functions by inhibiting the activity of serotonin, a neurotransmitter that activates the brain's vomiting center (chemoreceptor trigger zone, or CTZ).
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Composition :

ONDANSETRON-2MG

Manufacturer/Marketer :

Sun Pharmaceutical Industries Ltd

Consume Type :

PARENTERAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Zofer Injection 4 ml

Zofer Injection 4 ml is an antiemetic used to prevent and treat nausea and vomiting during chemotherapy. Nausea is a feeling of uneasiness in the stomach that often comes before vomiting. On the other hand, vomiting is the forcible voluntary or involuntary emptying of stomach contents through the mouth.

Zofer Injection 4 ml contains Ondansetron which works by blocking the action of serotonin, a chemical that stimulates the vomiting centre (chemoreceptor trigger zone – CTZ) located in the brain. Thus, it prevents nausea and vomiting. 

Zofer Injection 4 ml will be administered by a healthcare professional. Do not self-administer. In some cases, Zofer Injection 4 ml may cause headache, constipation, a feeling of warmth or flushing, redness, and irritation at the site of injection. Most of these side effects of Zofer Injection 4 ml do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor. 

If you are allergic to Ondansetron, Palanosetron, Granisetron, or any other medicines, please tell your doctor. Zofer Injection 4 ml should be given to children only in doses advised by the doctor based on the child’s body weight or body surface area. If you are pregnant or breastfeeding, you must inform your doctor before receiving Zofer Injection 4 ml.

Uses of Zofer Injection 4 ml

Prevention and treatment of nausea and vomiting

Directions for Use

Zofer Injection 4 ml will be administered by a healthcare professional. Do not self-administer.

Medicinal Benefits

Zofer Injection 4 ml contains Ondansetron that blocks the action of serotonin, a chemical that stimulates the vomiting centre (chemoreceptor trigger zone – CTZ) located in the brain. Thus, it prevents nausea and vomiting caused by chemotherapy in adults and children and also after surgery. Additionally, Zofer Injection 4 ml can be used to prevent nausea and vomiting caused by radiotherapy for cancer in adults.

How Zofer Injection 4 ml Works

Zofer Injection 4 ml contains Ondansetron which works by blocking the action of serotonin, a chemical that stimulates the vomiting centre (chemoreceptor trigger zone – CTZ) located in the brain. Thus, it prevents nausea and vomiting.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Zofer Injection 4 ml

  • Headache
  • Constipation
  • A feeling of warmth or flushing
  • Redness and irritation at the site of injection

What if I have taken an overdose of Zofer Injection 4 ml

Zofer Injection 4 ml is administered by a health care professional in a hospital setting. Hence, the chances of overdose are less. Symptoms of overdose may include sudden loss of vision, severe constipation, feeling light-headed, or fainting. There is no specific antidote for Ondansetron overdose. Your doctor may take necessary measures if an overdose is suspected.

Drug Warnings

If you are allergic to Ondansetron, Palanosetron, Granisetron, or any other medicines, please tell your doctor. Zofer Injection 4 ml should be given to children only in doses as advised by the doctor based on the child’s body weight or body surface area. Zofer Injection 4 ml should be used during pregnancy or breastfeeding after consultation with a doctor. If you have problems with levels of sodium, magnesium, and potassium salts in your blood, inform your doctor before taking Zofer Injection 4 ml. 

Diet & Lifestyle Advise

  • Eat a healthy and a low-fat diet, especially in small portions, as it will be easy for digestion. Avoid eating over-sweet food and include more salty food, especially if you have been vomiting.

  • Drink any other liquid at least 30 minutes after eating food. 

  • If the smell of food makes you feel sick (vomit), do not cook food as it may worsen your condition. Let someone else do the cooking or use prepared food from the freezer.

Habit Forming

No

Therapeutic Class

ANTIEMETICS

Zofer Injection 4 ml Substitute

Substitutes safety advice
  • Ondem Syrup 30 ml

    1.26per tablet
  • Emeset Juicy Lemon Syrup 30 ml

    1.26per tablet
  • Vomikind Syrup 30 ml

    1.25per tablet
  • Zofer Syrup 30 ml

    by AYUR

    1.26per tablet
  • Domi Up Spray 15ml

    by AYUR

    8.82per tablet
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Alcohol

Unsafe

Avoid consuming alcohol while taking Zofer Injection 4 ml as this medicine can interact with alcohol and may worsen the side effects.

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Pregnancy

Safe if prescribed

If you are pregnant, inform your doctor before taking Zofer Injection 4 ml. Your doctor will weigh the benefits and risks before prescribing this medicine.

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Breast Feeding

Safe if prescribed

If you are a nursing mother, inform your doctor before taking Zofer Injection 4 ml. Your doctor will weigh the benefits and risks before prescribing this medicine.

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Driving

Safe

Zofer Injection 4 ml usually does not affect your driving ability. However, do not drive if you feel any discomfort.

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Liver

Caution

Take Zofer Injection 4 ml with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Kidney

Safe if prescribed

Zofer Injection 4 ml may be safe to use in patients with kidney problems if prescribed by a doctor.

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Children

Caution

Zofer Injection 4 ml should be used in children only in doses advised by the doctor based on child’s body weight or body surface area.

FAQs

Zofer Injection 4 ml belongs to a class of drugs called antiemetics used to prevent nausea and vomiting during chemotherapy.
Zofer Injection 4 ml works by blocking the action of serotonin, a chemical that stimulates the vomiting centre (chemoreceptor trigger zone – CTZ) located in the brain. Thus, it prevents nausea and vomiting.
You are not recommended to take erythromycin with Zofer Injection 4 ml as it may increase the risk of severe irregular heart rhythm. However, please consult your doctor before taking other medicines with Zofer Injection 4 ml.
Zofer Injection 4 ml may cause constipation as a side effect. It is not necessary for everyone taking Zofer Injection 4 ml to experience this side effect. However, if the condition persists or worsens, please consult a doctor.
Zofer Injection 4 ml should be used with caution in patients suffering from liver problems. However, inform your doctor if you have any liver problems before taking Zofer Injection 4 ml so that the dose may be adjusted appropriately.
Yes, Zofer Injection 4 ml may be used to prevent nausea and vomiting after surgery. Zofer Injection 4 ml blocks serotonin (a chemical) action which is responsible for causing nausea and vomiting.

Country of origin

India

Manufacturer/Marketer address

Sun Pharmaceutical Industries Ltd., Sun House, Cts No. 201 B/1, Western Express Highway, Goregaon (E), Mumbai 400063
Other Info - ZOF0101

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