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Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Epinorm Syrup is used to prevent nausea and vomiting associated with moderately emetogenic cancer chemotherapy and radiotherapy in children. It also treats nausea and vomiting caused by stomach problems and surgery. It contains 'Ondanestron', which belongs to the serotonin 5-HT3 receptor antagonist. It works by blocking the action of a chemical called serotonin in the body, which is responsible for nausea and vomiting. As a result, Epinorm Syrup prevents the sensation of nausea and vomiting caused due to cancer chemotherapy.

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Composition :

ONDANSETRON-2MG

Manufacturer/Marketer :

Apex Laboratories Pvt Ltd

Consume Type :

ORAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Epinorm Syrup

Epinorm Syrup is an antiemetic medicine. It is used in the treatment of paediatric gastroenteritis in infants and children aged 6 months to 12 years. It is also used in the prevention of nausea and vomiting associated with moderately emetogenic cancer chemotherapy in children aged six months and above. Nausea is an uneasy feeling in which a person feels an urge to vomit, while vomiting is the natural response to the body to forcefully discharge the stomach contents.

Epinorm Syrup contains 'Ondanestron', which belongs to serotonin 5-HT3 receptor antagonists. It works by blocking the action of a chemical called serotonin in the body, which is responsible for causing nausea and vomiting. As a result, Epinorm Syrup prevents the sensation of nausea and vomiting caused by cancer chemotherapy.

Epinorm Syrup may cause certain side effects in your child, such as feeling of warmth, headache, diarrhoea, and stomach pain. These side effects generally resolve over time. However, if it does not resolve, stop giving this medicine to your child and contact the paediatrician. Do not give more than the prescribed dose of Epinorm Syrup to the child. Epinorm Syrup can be given with or without food. The dose of the medicine will be decided by your paediatrician.

Epinorm Syrup is intended for paediatric use only. Avoid giving Epinorm Syrup to your child if he/she is allergic to it. Keep your doctor informed about your child’s health condition, including his current medications and medical history, to rule out any side effects/interactions. Before administration, inform your doctor if your child has liver and kidney disease.

Uses of Epinorm Syrup

Treatment of Vomiting

Directions for Use

Epinorm Syrup is an oral solution (Oral drops). Shake the container well before each use. Measure the prescribed solution of Epinorm Syrup and administer them to your child. It is advised to measure the quantity accurately with the help of a dropper.

Medicinal Benefits

Epinorm Syrup contains 'Ondanestron' that belongs to serotonin 5-HT3 receptor antagonists. It works by blocking the action of a chemical called serotonin in the body which is responsible for causing nausea and vomiting. As a result, Epinorm Syrup prevents the sensation of nausea and vomiting caused due to cancer chemotherapy.

How Epinorm Syrup Works

Epinorm Syrup contains 'Ondanestron', which belongs to serotonin 5-HT3 receptor antagonists. It works by blocking the action of a chemical called serotonin in the body, which is responsible for causing nausea and vomiting. As a result, Epinorm Syrup prevents the sensation of nausea and vomiting caused by cancer chemotherapy.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Epinorm Syrup

  • Nausea
  • Diarrhoea
  • Stomach upset
  • Indigestion

What if I have taken an overdose of Epinorm Syrup

Please do not exceed the recommended dose, as it might cause an overdose. Signs and symptoms of an overdose of Epinorm Syrup may include constipation, dizziness or lightheadedness, fainting, irregular heartbeat, and sudden loss of vision for a short time. Seek immediate medical attention if you observe any symptoms or think you have taken too much. Do this even if there are no signs of discomfort or poisoning.

Drug Warnings

Avoid giving Epinorm Syrup to your child if he/she is allergic to it. Keep your doctor informed about your child’s health condition including his current medications and medical history to rule out any side effects/interactions. Before administration, inform your doctor if your child has liver and kidney disease. This medicine is intended for only paediatric population. Hence not recommended for use in special population (pregnant, breastfeeding mothers) and adults.

Drug-Drug Interactions

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OndansetronZiprasidone
Critical
OndansetronRizatriptan
Severe

Drug-Drug Interactions

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OndansetronZiprasidone
Critical
How does the drug interact with Epinorm Syrup 30 ml:
Taking Epinorm Syrup 30 ml with Ziprasidone can increase the risk of abnormal heart rhythm.

How to manage the interaction:
Taking Epinorm Syrup 30 ml with Ziprasidone is not recommended, but it can be taken together if prescribed by a doctor. However, consult a doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not discontinue any medications without consulting a doctor.
OndansetronRizatriptan
Severe
How does the drug interact with Epinorm Syrup 30 ml:
When Epinorm Syrup 30 ml, is taken with rizatriptan it increases the risk of serotonin syndrome (a condition in which a chemical called serotonin increase in body).

How to manage the interaction:
Although there is a possible interaction between Epinorm Syrup 30 ml and Rizatriptan, it can be taken if a doctor has advised it. If you notice any of these symptoms like confusion, hallucination, fits, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, shaking of hands and legs, incoordination, stomach cramps, nausea, vomiting, and loose stools, contact a doctor. Do not discontinue any medications without consulting a doctor.
OndansetronClozapine
Severe
How does the drug interact with Epinorm Syrup 30 ml:
Although it is a very rare adverse effect, taking Epinorm Syrup 30 ml with clozapine increases the risk of an abnormal heart rhythm.

How to manage the interaction:
Co-administration of Epinorm Syrup 30 ml along with clozapine can result in an interaction, it can be taken if a doctor has advised it. However, if you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, consult a doctor. Do not discontinue any medications without a doctor's advice.
OndansetronFluvoxamine
Severe
How does the drug interact with Epinorm Syrup 30 ml:
When Epinorm Syrup 30 ml is taken with fluvoxamine, can increase the risk of serotonin syndrome (a condition in which a chemical called serotonin builds up in body).

How to manage the interaction:
Co-administration of Epinorm Syrup 30 ml along with fluvoxamine can result in an interaction, it can be taken if a doctor has advised it. However, if you have sudden dizziness, lightheadedness, fainting, confusion, hallucination, fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles, or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea, or fast or rapid heartbeats during therapy, consult the doctor. Do not discontinue any medications without a doctor's advice.
OndansetronImipramine
Severe
How does the drug interact with Epinorm Syrup 30 ml:
Coadministration of Epinorm Syrup 30 ml along with imipramine can increase the risk of serotonin syndrome (a condition in which a chemical called serotonin builds up in body).

How to manage the interaction:
Taking Epinorm Syrup 30 ml along with imipramine together can result in an interaction, it can be taken if a doctor has advised it. However, if you have sudden dizziness, lightheadedness, fainting, confusion, hallucination, fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles, or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea, or fast or rapid heartbeats during therapy, consult the doctor. Do not discontinue any medications without consulting a doctor.
OndansetronVemurafenib
Severe
How does the drug interact with Epinorm Syrup 30 ml:
Although it is a very rare adverse effect, taking Epinorm Syrup 30 ml with vemurafenib increases the risk of an abnormal heart rhythm. If you're dealing with other heart illnesses or electrolyte imbalances (for example, magnesium or potassium loss likely due to serious or prolonged diarrhoea or vomiting), you may be at greater risk.

How to manage the interaction:
Although taking Epinorm Syrup 30 ml along with vemurafenib can possibly result in an interaction, it can be taken if your doctor has advised it. However, consult your doctor if you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat. Do not discontinue any medications without a doctor's advice
OndansetronDoxepin
Severe
How does the drug interact with Epinorm Syrup 30 ml:
When Epinorm Syrup 30 ml is taken with doxepin, it can increase the risk of serotonin syndrome (Serotonin syndrome is a condition in which a chemical called serotonin builds up in body).

How to manage the interaction:
Although taking Epinorm Syrup 30 ml along with doxepin can result in an interaction, it can be taken if a doctor has advised it. However, if you have sudden dizziness, lightheadedness, fainting, confusion, hallucination, fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles, or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea, or fast or rapid heartbeats during therapy, consult the doctor. Do not stop using any medications without talking to a doctor.
OndansetronOsimertinib
Severe
How does the drug interact with Epinorm Syrup 30 ml:
Taking Epinorm Syrup 30 ml with Osimertinib increases the risk of an abnormal heart rhythm.

How to manage the interaction:
Co-administration of Epinorm Syrup 30 ml along with Osimertinib can result in an interaction, it can be taken if a doctor has advised it. However, consult a doctor if you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat. Do not discontinue any medications without a doctor's advice.
OndansetronNilotinib
Severe
How does the drug interact with Epinorm Syrup 30 ml:
Taking Epinorm Syrup 30 ml with nilotinib increases the risk of an abnormal heart rhythm.

How to manage the interaction:
Co-administration of Epinorm Syrup 30 ml along with nilotinib can result in an interaction, it can be taken if a doctor has advised it. However, consult a doctor if you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat. Do not discontinue any medications without a doctor's advice.
OndansetronVandetanib
Severe
How does the drug interact with Epinorm Syrup 30 ml:
Taking Epinorm Syrup 30 ml with vandetanib increases the risk of an abnormal heart rhythm.

How to manage the interaction:
Although taking Epinorm Syrup 30 ml along with vandetanib can result in an interaction, it can be taken if a doctor has advised it. However, consult a doctor if you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat. Do not discontinue any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Certain food items/medicines are known to cause nausea/vomiting to your child.
  • Make your child drink more fluids to avoid dehydration.
  • Making your child take a healthy diet that includes lots of fruits and vegetables, nuts, and low-fat dairy products will help to keep your child in good health and avoid chances of nausea and vomiting. 
  • Avoid giving greasy or oily foods to your child as this food triggers nausea and vomiting. 

Habit Forming

No

Therapeutic Class

ANTIEMETICS

Epinorm Syrup Substitute

Substitutes safety advice
  • Ondem Syrup 30 ml

    1.26per tablet
  • Emeset Juicy Lemon Syrup 30 ml

    1.26per tablet
  • Vomikind Syrup 30 ml

    1.25per tablet
  • Zofer Syrup 30 ml

    by AYUR

    1.26per tablet
  • Domi Up Spray 15ml

    by AYUR

    9.69per tablet
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Alcohol

Not applicable

-

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Pregnancy

Not applicable

-

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Breast Feeding

Not applicable

-

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Driving

Not applicable

-

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Liver

Caution

If your child has a liver impairment, consult your doctor before using this medicine. Your doctor may weigh the benefits and risks before prescribing Epinorm Syrup.

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Kidney

Caution

If your child has a kidney impairment, consult your doctor before using this medicine. Your doctor may weigh the benefits and risks before prescribing Epinorm Syrup.

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Children

Safe if prescribed

Epinorm Syrup is safe for use in children if prescribed by the doctor. The dose of the medicine will be decided by your paediatrician. Do not give more than the recommended dose to your child.

FAQs

Epinorm Syrup is an antiemetic medicine. It is used in the treatment of paediatric gastroenteritis in infants and children aged 6 months to 12 years. It is also used in the prevention of nausea and vomiting associated with moderately emetogenic cancer chemotherapy in children aged six months and above.
Epinorm Syrup contains 'Ondanestron' that belongs to serotonin 5-HT3 receptor antagonist. It works by blocking the action of a chemical called serotonin in the body, which is responsible for nausea and vomiting.
Use it for as long as your paediatrician suggested.

Country of origin

India

Manufacturer/Marketer address

III Floor SIDCO Garment Complex, Guindy, Chennai 600 032, India
Other Info - EPI0185

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