OSIMERTINIB

Before taking the OSIMERTINIB, inform your doctor about all your medical conditions, sensitivities, and medications you are using. Exposure of an unborn child to this medication could cause birth defects, so you should not become pregnant or father a child while on this medication. Effective birth control is required throughout treatment and at least six weeks after treatment for women and four months after treatment for males. You should not breastfeed while taking this medication for two weeks after your last dose. Unless the doctor suggests, do not use any other medicine, including herbal or vitamin supplements. In rare cases, OSIMERTINIB therapy may lead to Interstitial lung disease (ILD)/Pneumonitis. Dyspnea, cough, and fever are the symptoms which may be indicative of ILD. If these symptoms worsen, contact your doctor right away. If ILD is confirmed, your doctor will discontinue the OSIMERTINIB therapy.

Drug-Drug Interactions: OSIMERTINIB may interact with medicines used to treat HIV infection (e.g. amprenavir, atazanavir, efavirenz), antibiotics (e.g. erythromycin, gatifloxacin), antidepressants (e.g. escitalopram), immunomodulating medication (e.g. fingolimod), anaesthetics (e.g. halothane) and vaccines (e.g. typhoid vaccine, live, smallpox vaccine, rotavirus vaccine) and antiarrhythmic agent (e.g. quinidine).

Drug-Food Interactions: Avoid the consumption of alcoholic beverages.

Drug-Disease Interactions: OSIMERTINIB interacts with disease conditions, including ILD (Interstitial lung disease)/Pneumonitis (inflammation in your lung tissues without an infection), infections (bacterial/fungal/protozoal/viral), ventricular arrhythmia, arrhythmias, congestive heart failure, dermatitis, ocular infection, pulmonary impairment, fever, renal dysfunction, liver disease.

• After your treatment begins, several dietary adjustments can help you control side effects.
• Anyone suffering from a chronic illness, including cancer, should consume foods high in protein, healthy fats, whole grains, and vitamins and minerals.
• Plant-based proteins are among the greatest meals during chemotherapy or other cancer treatments. They have the highest concentrations of vitamins and minerals, such as nuts, seeds, beans and legumes.
• Eat a healthy diet and exercise regularly to maintain proper weight.
• Include leafy vegetables, citrus fruits, fatty fish, berries, yoghurt, apples, peaches, cauliflower, cabbage, broccoli, beans, and herbs.
• De-stress yourself by meditating, reading books, taking a warm bubble bath or listening to soothing music.
• Performing yoga may also help in improving both physical and mental health.
• Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
• Get optimal sleep; rest well.
• Avoid smoking and alcohol consumption.
• Avoid fast food, fried food, processed meats, refined carbs and added sugars.

• Keep all appointments with your doctor and the laboratory. Your doctor will order certain tests to check your body's response to OSIMERTINIB.
• Pregnancy testing is recommended prior to starting treatment with OSIMERTINIB.