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Written By Veda Maddala , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy
Ondem Injection 10 x 2 ml is an antiemetic medication used in the treatmnet and prevention of nausea and vomiting during chemotherapy. This medication contains ondansetron which functions by inhibiting the activity of serotonin, a neurotransmitter that activates the brain's vomiting center (chemoreceptor trigger zone, or CTZ).
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Composition :

ONDANSETRON-2MG

Manufacturer/Marketer :

Alkem Laboratories Ltd

Consume Type :

PARENTERAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Ondem Injection 10 x 2 ml

Ondem Injection 10 x 2 ml is an antiemetic used to prevent and treat nausea and vomiting during chemotherapy. Nausea is a feeling of uneasiness in the stomach that often comes before vomiting. On the other hand, vomiting is the forcible voluntary or involuntary emptying of stomach contents through the mouth.

Ondem Injection 10 x 2 ml contains Ondansetron which works by blocking the action of serotonin, a chemical that stimulates the vomiting centre (chemoreceptor trigger zone – CTZ) located in the brain. Thus, it prevents nausea and vomiting. 

Ondem Injection 10 x 2 ml will be administered by a healthcare professional. Do not self-administer. In some cases, Ondem Injection 10 x 2 ml may cause headache, constipation, a feeling of warmth or flushing, redness, and irritation at the site of injection. Most of these side effects of Ondem Injection 10 x 2 ml do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor. 

If you are allergic to Ondansetron, Palanosetron, Granisetron, or any other medicines, please tell your doctor. Ondem Injection 10 x 2 ml should be given to children only in doses advised by the doctor based on the child’s body weight or body surface area. If you are pregnant or breastfeeding, you must inform your doctor before receiving Ondem Injection 10 x 2 ml .

Uses of Ondem Injection 10 x 2 ml

Prevention and treatment of nausea and vomiting

Directions for Use

Ondem Injection 10 x 2 ml will be administered by a healthcare professional. Do not self-administer.

Medicinal Benefits

Ondem Injection 10 x 2 ml contains Ondansetron that blocks the action of serotonin, a chemical that stimulates the vomiting centre (chemoreceptor trigger zone – CTZ) located in the brain. Thus, it prevents nausea and vomiting caused by chemotherapy in adults and children and also after surgery. Additionally, Ondem Injection 10 x 2 ml can be used to prevent nausea and vomiting caused by radiotherapy for cancer in adults.

How Ondem Injection 10 x 2 ml Works

Ondem Injection 10 x 2 ml contains Ondansetron which works by blocking the action of serotonin, a chemical that stimulates the vomiting centre (chemoreceptor trigger zone – CTZ) located in the brain. Thus, it prevents nausea and vomiting.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Ondem Injection 10 x 2 ml

  • Headache
  • Constipation
  • A feeling of warmth or flushing
  • Redness and irritation at the site of injection

What if I have taken an overdose of Ondem Injection 10 x 2 ml

Ondem Injection 10 x 2 ml is administered by a health care professional in a hospital setting. Hence, the chances of overdose are less. Symptoms of overdose may include sudden loss of vision, severe constipation, feeling light-headed, or fainting. There is no specific antidote for Ondansetron overdose. Your doctor may take necessary measures if an overdose is suspected.

Drug Warnings

If you are allergic to Ondansetron, Palanosetron, Granisetron, or any other medicines, please tell your doctor. Ondem Injection 10 x 2 ml should be given to children only in doses as advised by the doctor based on the child’s body weight or body surface area. Ondem Injection 10 x 2 ml should be used during pregnancy or breastfeeding after consultation with a doctor. If you have problems with levels of sodium, magnesium, and potassium salts in your blood, inform your doctor before taking Ondem Injection 10 x 2 ml . 

Drug-Drug Interactions

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OndansetronZiprasidone
Critical
OndansetronNortriptyline
Severe

Drug-Drug Interactions

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OndansetronZiprasidone
Critical
How does the drug interact with Ondem Injection 10 x 2 ml :
Taking Ondem Injection 10 x 2 ml with Ziprasidone can increase the risk of abnormal heart rhythm.

How to manage the interaction:
Taking Ondem Injection 10 x 2 ml with Ziprasidone is not recommended, but it can be taken together if prescribed by a doctor. However, consult a doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not discontinue any medications without consulting a doctor.
OndansetronNortriptyline
Severe
How does the drug interact with Ondem Injection 10 x 2 ml :
Using Nortriptyline together with Ondem Injection 10 x 2 ml can increase the risk of serotonin syndrome (a condition in which a chemical called serotonin builds up in body).

How to manage the interaction:
Co-administration of Ondem Injection 10 x 2 ml along with nortriptyline can result in an interaction, it can be taken if a doctor has advised it. However, consult a doctor if you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, heart palpitations, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, a shaking sensation, incoordination, stomach cramp, nausea, vomiting, or diarrhea. while taking these medications. Do not discontinue any medications without a doctor's advice.
OndansetronOsimertinib
Severe
How does the drug interact with Ondem Injection 10 x 2 ml :
Taking Ondem Injection 10 x 2 ml with Osimertinib increases the risk of an abnormal heart rhythm.

How to manage the interaction:
Co-administration of Ondem Injection 10 x 2 ml along with Osimertinib can result in an interaction, it can be taken if a doctor has advised it. However, consult a doctor if you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat. Do not discontinue any medications without a doctor's advice.
OndansetronParoxetine
Severe
How does the drug interact with Ondem Injection 10 x 2 ml :
When Ondem Injection 10 x 2 ml is taken with paroxetine, can increase the risk of serotonin syndrome (a condition in which a chemical called serotonin builds up in body).

How to manage the interaction:
Co-administration of Ondem Injection 10 x 2 ml along with paroxetine can result in an interaction, it can be taken if a doctor has advised it. However, if you have sudden dizziness, lightheadedness, fainting, confusion, hallucination, fits, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles, or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea, or fast or rapid heartbeats during therapy, consult the doctor. Do not stop using any medication without consulting a doctor.
OndansetronTranylcypromine
Severe
How does the drug interact with Ondem Injection 10 x 2 ml :
When Ondem Injection 10 x 2 ml , is taken with tranylcypromine it increases the risk of serotonin syndrome (a condition in which a chemical called serotonin increases in body).

How to manage the interaction:
Although taking Ondem Injection 10 x 2 ml along with tranylcypromine can lead to an interaction, it can be taken if recommended by a doctor. However, if you experience symptoms such as confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, a shaking sensation, incoordination, stomach cramp, nausea, vomiting, and diarrhea, see a doctor. Do not discontinue any medications without a doctor's advice.
OndansetronMethadone
Severe
How does the drug interact with Ondem Injection 10 x 2 ml :
Taking Ondem Injection 10 x 2 ml with methadone increases the risk of an abnormal heart rhythm.

How to manage the interaction:
Co-administration of Ondem Injection 10 x 2 ml along with methadone can result in an interaction, it can be taken if a doctor has advised it. However, if you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, consult a doctor. Do not discontinue any medications without a doctor's advice.
OndansetronDisopyramide
Severe
How does the drug interact with Ondem Injection 10 x 2 ml :
Taking Ondem Injection 10 x 2 ml with disopyramide increases the risk of an abnormal heart rhythm.

How to manage the interaction:
Although taking Ondem Injection 10 x 2 ml along with disopyramide can result in an interaction, it can be taken if a doctor has advised it. However, if you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, consult a doctor. Do not discontinue any medications without a doctor's advice.
OndansetronLithium
Severe
How does the drug interact with Ondem Injection 10 x 2 ml :
Taking Ondem Injection 10 x 2 ml with lithium can increase the risk of serotonin syndrome a condition in which a chemical called serotonin builds up in body).

How to manage the interaction:
Although taking Ondem Injection 10 x 2 ml along with lithium can result in an interaction but can be taken together if prescribed by a doctor. However, if you have sudden dizziness, lightheadedness, fainting, confusion, hallucination, fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles, or stiffness, incoordination, stomach cramps, nausea, vomiting, and loose stools, or fast or rapid heartbeats during therapy, consult a doctor. Do not stop using any medications without talking to a doctor.
OndansetronProtriptyline
Severe
How does the drug interact with Ondem Injection 10 x 2 ml :
When Ondem Injection 10 x 2 ml is taken with protriptyline, it can increase the risk of serotonin syndrome (Serotonin syndrome is a condition in which a chemical called serotonin builds up in body).

How to manage the interaction:
Although taking Ondem Injection 10 x 2 ml along with protriptyline can result in an interaction, it can be taken if a doctor has advised it. However, if you have sudden dizziness, lightheadedness, fainting, confusion, hallucination, fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles, or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea, or fast or rapid heartbeats during therapy, consult the doctor. Do not discontinue any medications without a doctor's advice.
OndansetronCeritinib
Severe
How does the drug interact with Ondem Injection 10 x 2 ml :
Taking ceritinib together with Ondem Injection 10 x 2 ml can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Co-administration of Ondem Injection 10 x 2 ml along with ceritinib can result in an interaction, but it can be taken together if prescribed by a doctor. However, consult a doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat a healthy and a low-fat diet, especially in small portions, as it will be easy for digestion. Avoid eating over-sweet food and include more salty food, especially if you have been vomiting.

  • Drink any other liquid at least 30 minutes after eating food. 

  • If the smell of food makes you feel sick (vomit), do not cook food as it may worsen your condition. Let someone else do the cooking or use prepared food from the freezer.

Habit Forming

No

Therapeutic Class

ANTIEMETICS

Ondem Injection 10 x 2 ml Substitute

Substitutes safety advice
  • Ondem Syrup 30 ml

    1.26per tablet
  • Emeset Juicy Lemon Syrup 30 ml

    1.26per tablet
  • Vomikind Syrup 30 ml

    1.25per tablet
  • Zofer Syrup 30 ml

    by AYUR

    1.26per tablet
  • Domi Up Spray 15ml

    by AYUR

    9.69per tablet
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Alcohol

Unsafe

Avoid consuming alcohol while taking Ondem Injection 10 x 2 ml as this medicine can interact with alcohol and may worsen the side effects.

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Pregnancy

Safe if prescribed

If you are pregnant, inform your doctor before taking Ondem Injection 10 x 2 ml . Your doctor will weigh the benefits and risks before prescribing this medicine.

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Breast Feeding

Safe if prescribed

If you are a nursing mother, inform your doctor before taking Ondem Injection 10 x 2 ml . Your doctor will weigh the benefits and risks before prescribing this medicine.

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Driving

Safe

Ondem Injection 10 x 2 ml usually does not affect your driving ability. However, do not drive if you feel any discomfort.

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Liver

Caution

Take Ondem Injection 10 x 2 ml with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Kidney

Safe if prescribed

Ondem Injection 10 x 2 ml may be safe to use in patients with kidney problems if prescribed by a doctor.

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Children

Caution

Ondem Injection 10 x 2 ml should be used in children only in doses advised by the doctor based on child’s body weight or body surface area.

FAQs

Ondem Injection 10 x 2 ml belongs to a class of drugs called antiemetics used to prevent nausea and vomiting during chemotherapy.
Ondem Injection 10 x 2 ml works by blocking the action of serotonin, a chemical that stimulates the vomiting centre (chemoreceptor trigger zone – CTZ) located in the brain. Thus, it prevents nausea and vomiting.
You are not recommended to take erythromycin with Ondem Injection 10 x 2 ml as it may increase the risk of severe irregular heart rhythm. However, please consult your doctor before taking other medicines with Ondem Injection 10 x 2 ml .
Ondem Injection 10 x 2 ml may cause constipation as a side effect. It is not necessary for everyone taking Ondem Injection 10 x 2 ml to experience this side effect. However, if the condition persists or worsens, please consult a doctor.
Ondem Injection 10 x 2 ml should be used with caution in patients suffering from liver problems. However, inform your doctor if you have any liver problems before taking Ondem Injection 10 x 2 ml so that the dose may be adjusted appropriately.
Yes, Ondem Injection 10 x 2 ml may be used to prevent nausea and vomiting after surgery. Ondem Injection 10 x 2 ml blocks serotonin (a chemical) action which is responsible for causing nausea and vomiting.

Country of origin

India

Manufacturer/Marketer address

Alkem Laboratories Limited, Devashish Building, Alkem House, Senapati Bapat Road, Lower Parel, Mumbai - 400 013.
Other Info - OND0004

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