apollo
0
Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Sirova 1mg Tablet is used to prevent organ rejection after a transplant. It contains Sirolimus which works by weakening the body's defence system (immune system) and assisting the body in accepting the new organ. In some cases, this medicine may cause side effects like abdominal pain, diarrhoea, headache, fever, urinary tract infection, anaemia, nausea, pain, and oedema.
Read more
rxMedicinePrescription drug

Whats That

tooltip

Composition :

SIROLIMUS-1MG

Manufacturer/Marketer :

Intas Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

About Sirova 1mg Tablet

Sirova 1mg Tablet belongs to a class of drugs called 'immunosuppressants' used to prevent organ rejection after a transplant. Organ rejection occurs when a patient's immune system recognizes the donor organ as foreign and tries to eliminate it.

Sirova 1mg Tablet contains Sirolimus is an immunosuppressant. It weakens your body's defence system (immune system) to help your body accept the new organ as if it were your own. Thereby preventing organ rejection in transplanted patients and assisting the body in accepting the new organ.

Use Sirova 1mg Tablet as prescribed by your doctor. You are advised to use Sirova 1mg Tablet for as long as your doctor has prescribed it based on your medical condition. Some people may experience abdominal pain, diarrhoea, headache, fever, urinary tract infection, anaemia, nausea, arthralgia, pain, and oedema. Most of these side effects of Sirova 1mg Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

To treat your condition effectually, continue using Sirova 1mg Tablet for as long as your doctor has prescribed it. Do not use Sirova 1mg Tablet without a doctor's advice if you are allergic to Sirova 1mg Tablet or other medicines. Consult your doctor before using Sirova 1mg Tablet if you are pregnant or breastfeeding. Avoid alcohol consumption with Sirova 1mg Tablet as it may increase the risk of severe adverse effects. Keep your doctor informed about your health condition and all the medicines you take before taking Sirova 1mg Tablet to rule out any side effects.

Uses of Sirova 1mg Tablet

Used to prevent organ rejection

Directions for Use

Swallow it as a whole with water; do not crush, break or chew it.

Medicinal Benefits

Sirova 1mg Tablet contains Sirolimus is an immunosuppressant. It weakens your body's defence system (immune system) to help your body accept the new organ as if it were your own. Thereby preventing organ rejection in transplanted patients and assisting the body in accepting the new organ.

How Sirova 1mg Tablet Works

Sirova 1mg Tablet contains Sirolimus is an immunosuppressant. It weakens your body's defence system (immune system) to help your body accept the new organ as if it were your own. Thereby preventing organ rejection in transplanted patients and assisting the body in accepting the new organ.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Sirova 1mg Tablet

  • Peripheral oedema
  • Hypertriglyceridemia
  • Hypertension
  • Hypercholesterolemia
  • Creatinine increased
  • Abdominal pain
  • Diarrhoea
  • Headache
  • Fever
  • Urinary tract infection
  • Anaemia
  • Nausea
  • Arthralgia
  • Pain
  • Thrombocytopenia

What if I have taken an overdose of Sirova 1mg Tablet

Take Sirova 1mg Tablet only as prescribed by the physician. Do not exceed the recommended dose, as it might cause an overdose. If you suspect you have taken an overdose, seek immediate medical attention.

Drug Warnings

Therapeutic drug monitoring is required for all patients receiving Sirova 1mg Tablet. To treat your condition effectually, continue using Sirova 1mg Tablet for as long as your doctor has prescribed it. Do not use Sirova 1mg Tablet without a doctor's advice if you are allergic to Sirova 1mg Tablet or other medicines. Consult your doctor before using the Sirova 1mg Tablet if you are pregnant or breastfeeding. Avoid alcohol consumption with Sirova 1mg Tablet as it may increase the risk of severe adverse effects. Do not use Sirova 1mg Tablet in more than prescribed doses or longer duration as it may cause adverse effects. And also, keep your doctor informed about your health condition and all the medicines you take before taking Sirova 1mg Tablet to rule out any side effects.

Drug-Drug Interactions

verifiedApollotooltip
SirolimusBCG vaccine
Critical
SirolimusPosaconazole
Critical

Drug-Drug Interactions

Login/Sign Up

SirolimusBCG vaccine
Critical
How does the drug interact with Sirova 1mg Tablet:
Coadministration of Sirova 1mg Tablet with the BCG vaccine can make the vaccine less effective.

How to manage the interaction:
Taking Sirova 1mg Tablet with the BCG vaccine is not recommended, they can be taken together if advised by your doctor. However, contact your doctor if you experience any symptoms. Do not stop taking any medications without consulting a doctor.
SirolimusPosaconazole
Critical
How does the drug interact with Sirova 1mg Tablet:
Coadministration of Sirova 1mg Tablet with posaconazole can lower the levels of Sirova 1mg Tablet in the blood.

How to manage the interaction:
Although there is an interaction between posaconazole with Sirova 1mg Tablet, they can be taken together if a doctor advises. However, if you experience any unusual symptoms contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
SirolimusMifepristone
Critical
How does the drug interact with Sirova 1mg Tablet:
Coadministration of Sirova 1mg Tablet with Mifepristone can increase the levels of Sirova 1mg Tablet in the blood, which can increase the risk or severity of side effects.

How to manage the interaction:
Taking Sirova 1mg Tablet with Mifepristone is not recommended, they can be taken together if a doctor advises. However, contact a doctor if you experience any symptoms like back pain · difficulty falling asleep or staying asleep, fever, headache, joint pain, rash, stomach pain, constipation, or diarrhea. Do not stop taking any medications without consulting a doctor.
SirolimusCidofovir
Critical
How does the drug interact with Sirova 1mg Tablet:
Co-administration of Cidofovir and Sirova 1mg Tablet can increase the risk or severity of Kidney problems.

How to manage the interaction:
Taking Sirova 1mg Tablet with Cidofovir is not recommended, but it can be taken together if prescribed by a doctor. However, if you experience nausea, vomiting, loss of hunger, increased or decreased urination, sudden weight gain or loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, or an irregular heart rhythm, consult a doctor. Do not discontinue any medications without consulting a doctor.
SirolimusVoriconazole
Critical
How does the drug interact with Sirova 1mg Tablet:
Coadministration of Sirova 1mg Tablet and Voriconazole can increase blood levels and side effects of Voriconazole.

How to manage the interaction:
Taking Voriconazole with Sirova 1mg Tablet is generally avoided as it can result in an interaction, please consult a doctor before taking it. Contact a doctor if you experience nausea, fever, abdominal pain, or yellowing of the skin or eyes. Do not stop using any medication without consulting a doctor.
SirolimusLithium
Severe
How does the drug interact with Sirova 1mg Tablet:
Coadministration of Sirova 1mg Tablet with Lithium together may increase the risk or severity of kidney problems.

How to manage the interaction:
Although taking Lithium and Sirova 1mg Tablet together can cause an interaction, it can be taken if a doctor has suggested it. However, consult the doctor immediately if you experience symptoms such as nausea, vomiting, loss of hunger, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. Do not discontinue any medications without consulting a doctor.
SirolimusEtanercept
Severe
How does the drug interact with Sirova 1mg Tablet:
Coadministration of Etanercept with Sirova 1mg Tablet, may increase the risk or severity of developing serious infection.

How to manage the interaction:
Although there is a possible interaction between Sirova 1mg Tablet and Etanercept, you can take these medicines together if prescribed by a doctor. However, if you develop fever, chills, diarrhea, sore throat, muscular pains, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning during urination, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
SirolimusPolymyxin b
Severe
How does the drug interact with Sirova 1mg Tablet:
Co-administration of Sirova 1mg Tablet and Polymyxin B together may increase the risk or severity of kidney problems.

How to manage the interaction:
There may be a possibility of interaction between Sirova 1mg Tablet and Polymyxin b, but it can be taken if prescribed by a doctor. However, if you experience nausea, vomiting, a decrease in hunger, increased or decreased urine, weight gain or loss that occurs suddenly, fluid retention, swelling, difficulty breathing, bone pain, muscle pain, fatigue, weakness, dizziness, confusion, and irregular heartbeat, consult a doctor. Do not discontinue any medications without a doctor's advice.
SirolimusCapreomycin
Severe
How does the drug interact with Sirova 1mg Tablet:
Co-administration of Capreomycin and Sirova 1mg Tablet together can increase the risk or severity of kidney problems.

How to manage the interaction:
Although taking Sirova 1mg Tablet and Capreomycin together can evidently cause an interaction, but it can be taken if a doctor has suggested it. However, if you experience nausea, vomiting, a decrease in hunger, increased or decreased urine, weight gain or loss that occurs suddenly, fluid retention, swelling, difficulty breathing, muscle pain, fatigue, weakness, dizziness, confusion, and irregular heartbeat, consult a doctor. Do not discontinue any medications without a doctor's advice.
SirolimusVancomycin
Severe
How does the drug interact with Sirova 1mg Tablet:
Coadministration of Vancomycin with Sirova 1mg Tablet can increase the risk or severity of kidney problems.

How to manage the interaction:
Taking Vancomycin with Sirova 1mg Tablet may result in an interaction, they can be taken together if prescribed by a doctor. However, contact a doctor immediately if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. Do not discontinue any medication without consulting a doctor.

Drug-Food Interactions

verifiedApollotooltip
SIROLIMUS-1MGGrapefruit and Grapefruit Juice
Moderate

Drug-Food Interactions

Login/Sign Up

SIROLIMUS-1MGGrapefruit and Grapefruit Juice
Moderate
Common Foods to Avoid:
Grapefruit Juice, Grapefruit

How to manage the interaction:
Taking Sirova 1mg Tablet with Grapefruit and Grapefruit juice may increase the side effects of Sirova 1mg Tablet. Avoid or limit consumption of Grapefruit and Grapefruit juice while taking Sirova 1mg Tablet.

Habit Forming

No

Therapeutic Class

IMMUNOSUPPRESSANTS

Sirova 1mg Tablet Substitute

Substitutes safety advice
  • Siromus Tablet 6's

    by AYUR

    159.15per tablet
  • Rapasim Tablet 10's

    146.39per tablet
  • RAPACAN 1MG TABLET

    244.02per tablet
  • Raparen 1 Tablet 10's

    155.79per tablet
  • SIROPAN TABLET

    207.32per tablet
bannner image

Alcohol

Caution

It is advised to avoid alcohol intake since it may worsen the side effects.

bannner image

Pregnancy

Caution

Consult your doctor, and there is no substantial research yet on the use of Sirova 1mg Tablet in pregnant women.

bannner image

Breast Feeding

Caution

Consult your doctor, and there is no substantial research yet on the use of Sirova 1mg Tablet in breastfeeding/nursing mothers.

bannner image

Driving

Caution

Do not drive or operate machinery if you experience dizziness or drowsiness while using Sirova 1mg Tablet. Sirova 1mg Tablet can also sometimes cause dizziness/drowsiness; hence avoid driving in such situations. Seek medical attention if the symptoms persist longer.

bannner image

Liver

Caution

Please consult your doctor if you have any concerns regarding using Sirova 1mg Tablet in patients with liver impairment. Your doctor will prescribe only if the benefits outweigh the risks.

bannner image

Kidney

Caution

Please consult your doctor if you have any concerns regarding using Sirova 1mg Tablet in patients with kidney impairment. Your doctor will prescribe only if the benefits outweigh the risks.

bannner image

Children

Caution

There is limited information available on the use of Sirova 1mg Tablet in children. Please consult your doctor.

FAQs

Sirova 1mg Tablet is used to prevent organ rejection after a transplant.
Sirova 1mg Tablet contains Sirolimus is an immunosuppressant. It works by weakening your body's defence system (immune system) to help your body accept the new organ as if it were your own.
No, it is a prescribed drug given by a physician for preventing specific medical conditions. Taking it on your own can cause unwanted side effects.
Sirova 1mg Tablet is safe if used in the dose and duration recommended by your doctor. Take it exactly as directed, and do not skip any dose. Follow your doctor's guidelines carefully and inform your doctor if any of the side effects disturb you.
Please do not stop using Sirova 1mg Tablet without consulting your doctor on your own. Continue using Sirova 1mg Tablet for as long as your doctor has prescribed it to treat your condition effectually. Do not be reluctant to speak with your doctor if you experience any difficulty while taking Sirova 1mg Tablet.
Take the missed dose as soon as possible. However, skip the missed dose and return to your regular dosing schedule if it is time for the next dose.

Country of origin

India
Other Info - SI30250

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
whatsapp Floating Button