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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Oct 9, 2024 | 12:37 PM IST
SIROPAN TABLET is used to prevent organ rejection after a transplant. It contains Sirolimus which works by weakening the body's defence system (immune system) and assisting the body in accepting the new organ. In some cases, this medicine may cause side effects like abdominal pain, diarrhoea, headache, fever, urinary tract infection, anaemia, nausea, pain, and oedema.
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Prescription drug

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Prescription drug
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Composition

SIROLIMUS-1MG

Manufacturer/Marketer

Panacea Biotec Ltd

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About SIROPAN TABLET

SIROPAN TABLET belongs to a class of drugs called 'immunosuppressants' used to prevent organ rejection after a transplant. Organ rejection occurs when a patient's immune system recognizes the donor organ as foreign and tries to eliminate it.

SIROPAN TABLET contains Sirolimus is an immunosuppressant. It weakens your body's defence system (immune system) to help your body accept the new organ as if it were your own. Thereby preventing organ rejection in transplanted patients and assisting the body in accepting the new organ.

Use SIROPAN TABLET as prescribed by your doctor. You are advised to use SIROPAN TABLET for as long as your doctor has prescribed it based on your medical condition. Some people may experience abdominal pain, diarrhoea, headache, fever, urinary tract infection, anaemia, nausea, arthralgia, pain, and oedema. Most of these side effects of SIROPAN TABLET do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

To treat your condition effectually, continue using SIROPAN TABLET for as long as your doctor has prescribed it. Do not use SIROPAN TABLET without a doctor's advice if you are allergic to SIROPAN TABLET or other medicines. Consult your doctor before using SIROPAN TABLET if you are pregnant or breastfeeding. Avoid alcohol consumption with SIROPAN TABLET as it may increase the risk of severe adverse effects. Keep your doctor informed about your health condition and all the medicines you take before taking SIROPAN TABLET to rule out any side effects.

Uses of SIROPAN TABLET

Used to prevent organ rejection

Medicinal Benefits

SIROPAN TABLET contains Sirolimus is an immunosuppressant. It weakens your body's defence system (immune system) to help your body accept the new organ as if it were your own. Thereby preventing organ rejection in transplanted patients and assisting the body in accepting the new organ.

Directions for Use

Swallow it as a whole with water; do not crush, break or chew it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of SIROPAN TABLET

  • Peripheral oedema
  • Hypertriglyceridemia
  • Hypertension
  • Hypercholesterolemia
  • Creatinine increased
  • Abdominal pain
  • Diarrhoea
  • Headache
  • Fever
  • Urinary tract infection
  • Anaemia
  • Nausea
  • Arthralgia
  • Pain
  • Thrombocytopenia

Drug Warnings

Therapeutic drug monitoring is required for all patients receiving SIROPAN TABLET. To treat your condition effectually, continue using SIROPAN TABLET for as long as your doctor has prescribed it. Do not use SIROPAN TABLET without a doctor's advice if you are allergic to SIROPAN TABLET or other medicines. Consult your doctor before using the SIROPAN TABLET if you are pregnant or breastfeeding. Avoid alcohol consumption with SIROPAN TABLET as it may increase the risk of severe adverse effects. Do not use SIROPAN TABLET in more than prescribed doses or longer duration as it may cause adverse effects. And also, keep your doctor informed about your health condition and all the medicines you take before taking SIROPAN TABLET to rule out any side effects.

Drug Interactions

Drug-Drug Interactions: SIROPAN TABLET may interact with other immunosuppressive agents (e.g. mycophenolate mofetil, mycophenolic acid), antihistamines (e.g. loratadine), anti-hypertensive medicines (e.g. losartan), and diabetic medicines (e.g. insulin glargine, insulin aspart). The relevance of a particular drug interaction varies from person to person. Always consult your healthcare provider before starting or stopping any medication, and also inform your doctor of all your medical conditions and ongoing therapies before prescribing this medication. Considering these, your doctor may check the drug interactions before prescribing this medication.

Drug-Food Interactions: Avoid consumption of alcohol, eating grapefruit or drinking grapefruit juice while you are taking SIROPAN TABLET.

Drug-Disease Interactions: Brief your doctor if you have a medical history of allergic reactions to medicines, Infections, PML (progressive multifocal leukoencephalopathy), angioedema, hyperlipidemia, liver disease, liver transplantation, lung dysfunction, lung transplant, renal dysfunction before taking SIROPAN TABLET.

Drug-Drug Interactions Checker List

  • MYCOPHENOLATE MOFETIL
  • MYCOPHENOLIC ACID
  • LORATADINE
  • LOSARTAN
  • INSULIN ASPART
  • INSULIN GLARGINE

Habit Forming

No

Disease/Condition Glossary

Organ rejection occurs when a patient’s immune system recognizes the donor organ as foreign and tries to eliminate it.

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Alcohol

Caution

It is advised to avoid alcohol intake since it may worsen the side effects.

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Pregnancy

Caution

Consult your doctor, and there is no substantial research yet on the use of SIROPAN TABLET in pregnant women.

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Breast Feeding

Caution

Consult your doctor, and there is no substantial research yet on the use of SIROPAN TABLET in breastfeeding/nursing mothers.

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Driving

Caution

Do not drive or operate machinery if you experience dizziness or drowsiness while using SIROPAN TABLET. SIROPAN TABLET can also sometimes cause dizziness/drowsiness; hence avoid driving in such situations. Seek medical attention if the symptoms persist longer.

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Liver

Caution

Please consult your doctor if you have any concerns regarding using SIROPAN TABLET in patients with liver impairment. Your doctor will prescribe only if the benefits outweigh the risks.

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Kidney

Caution

Please consult your doctor if you have any concerns regarding using SIROPAN TABLET in patients with kidney impairment. Your doctor will prescribe only if the benefits outweigh the risks.

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Children

Caution

There is limited information available on the use of SIROPAN TABLET in children. Please consult your doctor.

Country of origin

India

Manufacturer/Marketer address

Ambala- Chandigarh Highway, Lalru – 140501, Punjab
Other Info - SIR0002

Author Details

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FAQs

SIROPAN TABLET is used to prevent organ rejection after a transplant.
SIROPAN TABLET contains Sirolimus is an immunosuppressant. It works by weakening your body's defence system (immune system) to help your body accept the new organ as if it were your own.
No, it is a prescribed drug given by a physician for preventing specific medical conditions. Taking it on your own can cause unwanted side effects.
SIROPAN TABLET is safe if used in the dose and duration recommended by your doctor. Take it exactly as directed, and do not skip any dose. Follow your doctor's guidelines carefully and inform your doctor if any of the side effects disturb you.
Please do not stop using SIROPAN TABLET without consulting your doctor on your own. Continue using SIROPAN TABLET for as long as your doctor has prescribed it to treat your condition effectually. Do not be reluctant to speak with your doctor if you experience any difficulty while taking SIROPAN TABLET.
Take the missed dose as soon as possible. However, skip the missed dose and return to your regular dosing schedule if it is time for the next dose.

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