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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
RAPACAN 1MG TABLET is used to prevent organ rejection after a transplant. It contains Sirolimus which works by weakening the body's defence system (immune system) and assisting the body in accepting the new organ. In some cases, this medicine may cause side effects like abdominal pain, diarrhoea, headache, fever, urinary tract infection, anaemia, nausea, pain, and oedema.
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Whats That

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Composition :

SIROLIMUS-1MG

Manufacturer/Marketer :

Biocon Ltd

Consume Type :

ORAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About RAPACAN 1MG TABLET

RAPACAN 1MG TABLET belongs to a class of drugs called 'immunosuppressants' used to prevent organ rejection after a transplant. Organ rejection occurs when a patient's immune system recognizes the donor organ as foreign and tries to eliminate it.

RAPACAN 1MG TABLET contains Sirolimus is an immunosuppressant. It weakens your body's defence system (immune system) to help your body accept the new organ as if it were your own. Thereby preventing organ rejection in transplanted patients and assisting the body in accepting the new organ.

Use RAPACAN 1MG TABLET as prescribed by your doctor. You are advised to use RAPACAN 1MG TABLET for as long as your doctor has prescribed it based on your medical condition. Some people may experience abdominal pain, diarrhoea, headache, fever, urinary tract infection, anaemia, nausea, arthralgia, pain, and oedema. Most of these side effects of RAPACAN 1MG TABLET do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

To treat your condition effectually, continue using RAPACAN 1MG TABLET for as long as your doctor has prescribed it. Do not use RAPACAN 1MG TABLET without a doctor's advice if you are allergic to RAPACAN 1MG TABLET or other medicines. Consult your doctor before using RAPACAN 1MG TABLET if you are pregnant or breastfeeding. Avoid alcohol consumption with RAPACAN 1MG TABLET as it may increase the risk of severe adverse effects. Keep your doctor informed about your health condition and all the medicines you take before taking RAPACAN 1MG TABLET to rule out any side effects.

Uses of RAPACAN 1MG TABLET

Used to prevent organ rejection

Directions for Use

Swallow it as a whole with water; do not crush, break or chew it.

Medicinal Benefits

RAPACAN 1MG TABLET contains Sirolimus is an immunosuppressant. It weakens your body's defence system (immune system) to help your body accept the new organ as if it were your own. Thereby preventing organ rejection in transplanted patients and assisting the body in accepting the new organ.

How RAPACAN 1MG TABLET Works

RAPACAN 1MG TABLET contains Sirolimus is an immunosuppressant. It weakens your body's defence system (immune system) to help your body accept the new organ as if it were your own. Thereby preventing organ rejection in transplanted patients and assisting the body in accepting the new organ.

Storage

Store in a cool and dry place away from sunlight

Side Effects of RAPACAN 1MG TABLET

  • Peripheral oedema
  • Hypertriglyceridemia
  • Hypertension
  • Hypercholesterolemia
  • Creatinine increased
  • Abdominal pain
  • Diarrhoea
  • Headache
  • Fever
  • Urinary tract infection
  • Anaemia
  • Nausea
  • Arthralgia
  • Pain
  • Thrombocytopenia

What if I have taken an overdose of RAPACAN 1MG TABLET

Take RAPACAN 1MG TABLET only as prescribed by the physician. Do not exceed the recommended dose, as it might cause an overdose. If you suspect you have taken an overdose, seek immediate medical attention.

Drug Warnings

Therapeutic drug monitoring is required for all patients receiving RAPACAN 1MG TABLET. To treat your condition effectually, continue using RAPACAN 1MG TABLET for as long as your doctor has prescribed it. Do not use RAPACAN 1MG TABLET without a doctor's advice if you are allergic to RAPACAN 1MG TABLET or other medicines. Consult your doctor before using the RAPACAN 1MG TABLET if you are pregnant or breastfeeding. Avoid alcohol consumption with RAPACAN 1MG TABLET as it may increase the risk of severe adverse effects. Do not use RAPACAN 1MG TABLET in more than prescribed doses or longer duration as it may cause adverse effects. And also, keep your doctor informed about your health condition and all the medicines you take before taking RAPACAN 1MG TABLET to rule out any side effects.

Drug-Drug Interactions

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SirolimusBCG vaccine
Critical
SirolimusVoriconazole
Critical

Drug-Drug Interactions

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SirolimusBCG vaccine
Critical
How does the drug interact with RAPACAN 1MG TABLET:
Coadministration of RAPACAN 1MG TABLET with the BCG vaccine can make the vaccine less effective.

How to manage the interaction:
Taking RAPACAN 1MG TABLET with the BCG vaccine is not recommended, they can be taken together if advised by your doctor. However, contact your doctor if you experience any symptoms. Do not stop taking any medications without consulting a doctor.
SirolimusVoriconazole
Critical
How does the drug interact with RAPACAN 1MG TABLET:
Coadministration of RAPACAN 1MG TABLET and Voriconazole can increase blood levels and side effects of Voriconazole.

How to manage the interaction:
Taking Voriconazole with RAPACAN 1MG TABLET is generally avoided as it can result in an interaction, please consult a doctor before taking it. Contact a doctor if you experience nausea, fever, abdominal pain, or yellowing of the skin or eyes. Do not stop using any medication without consulting a doctor.
SirolimusMifepristone
Critical
How does the drug interact with RAPACAN 1MG TABLET:
Coadministration of RAPACAN 1MG TABLET with Mifepristone can increase the levels of RAPACAN 1MG TABLET in the blood, which can increase the risk or severity of side effects.

How to manage the interaction:
Taking RAPACAN 1MG TABLET with Mifepristone is not recommended, they can be taken together if a doctor advises. However, contact a doctor if you experience any symptoms like back pain · difficulty falling asleep or staying asleep, fever, headache, joint pain, rash, stomach pain, constipation, or diarrhea. Do not stop taking any medications without consulting a doctor.
SirolimusPosaconazole
Critical
How does the drug interact with RAPACAN 1MG TABLET:
Coadministration of RAPACAN 1MG TABLET with posaconazole can lower the levels of RAPACAN 1MG TABLET in the blood.

How to manage the interaction:
Although there is an interaction between posaconazole with RAPACAN 1MG TABLET, they can be taken together if a doctor advises. However, if you experience any unusual symptoms contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
SirolimusCidofovir
Critical
How does the drug interact with RAPACAN 1MG TABLET:
Co-administration of Cidofovir and RAPACAN 1MG TABLET can increase the risk or severity of Kidney problems.

How to manage the interaction:
Taking RAPACAN 1MG TABLET with Cidofovir is not recommended, but it can be taken together if prescribed by a doctor. However, if you experience nausea, vomiting, loss of hunger, increased or decreased urination, sudden weight gain or loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, or an irregular heart rhythm, consult a doctor. Do not discontinue any medications without consulting a doctor.
SirolimusCladribine
Severe
How does the drug interact with RAPACAN 1MG TABLET:
Co-administration of Cladribine with RAPACAN 1MG TABLET can increase the risk and severity of developing infections.

How to manage the interaction:
Although there is a possible interaction between RAPACAN 1MG TABLET and Cladribine, you can take these medicines together if prescribed by a doctor. However, if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning sensation when you urinate, consult a doctor. Do not stop using any medications without a doctor's advice.
SirolimusKetorolac
Severe
How does the drug interact with RAPACAN 1MG TABLET:
Co-administration of RAPACAN 1MG TABLET and Ketorolac may increase the risk or severity of kidney issues.

How to manage the interaction:
Although taking Ketorolac and RAPACAN 1MG TABLET together can possibly result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience symptoms like nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or loss, fluid retention, swelling, shortness of breath, cramps in your muscles, fatigue, weakness, dizziness, confusion, and irregular heartbeat, consult a doctor. Do not stop using any medication without consulting your doctor.
SirolimusBaricitinib
Severe
How does the drug interact with RAPACAN 1MG TABLET:
Co-administration of Baricitinib and RAPACAN 1MG TABLET can increase the risk or severity of serious infections.

How to manage the interaction:
Although there is an interaction, baricitinib can be taken with RAPACAN 1MG TABLET if prescribed by the doctor. However, if you experience fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning when you urinate, consult a doctor. Do not stop using any medication without consulting a doctor.
SirolimusDiclofenac
Severe
How does the drug interact with RAPACAN 1MG TABLET:
Co-administration of Diclofenac with RAPACAN 1MG TABLET may increase the risk or severity of kidney problems.

How to manage the interaction:
Co-administration of Diclofenac and RAPACAN 1MG TABLET can lead to an interaction, but it can be taken if advised by a doctor. However, consult a doctor if you experience any symptoms like nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. Do not discontinue any medications without consulting a doctor.
SirolimusLithium
Severe
How does the drug interact with RAPACAN 1MG TABLET:
Coadministration of RAPACAN 1MG TABLET with Lithium together may increase the risk or severity of kidney problems.

How to manage the interaction:
Although taking Lithium and RAPACAN 1MG TABLET together can cause an interaction, it can be taken if a doctor has suggested it. However, consult the doctor immediately if you experience symptoms such as nausea, vomiting, loss of hunger, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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SIROLIMUS-1MGGrapefruit and Grapefruit Juice
Moderate

Drug-Food Interactions

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SIROLIMUS-1MGGrapefruit and Grapefruit Juice
Moderate
Common Foods to Avoid:
Grapefruit Juice, Grapefruit

How to manage the interaction:
Taking RAPACAN 1MG TABLET with Grapefruit and Grapefruit juice may increase the side effects of RAPACAN 1MG TABLET. Avoid or limit consumption of Grapefruit and Grapefruit juice while taking RAPACAN 1MG TABLET.

Habit Forming

No

Therapeutic Class

IMMUNOSUPPRESSANTS

RAPACAN 1MG TABLET Substitute

Substitutes safety advice
  • Siromus Tablet 6's

    by AYUR

    159.15per tablet
  • Rapasim Tablet 10's

    146.39per tablet
  • Raparen 1 Tablet 10's

    155.79per tablet
  • SIROPAN TABLET

    207.32per tablet
  • ROCAS TABLET

    19.20per tablet
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Alcohol

Caution

It is advised to avoid alcohol intake since it may worsen the side effects.

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Pregnancy

Caution

Consult your doctor, and there is no substantial research yet on the use of RAPACAN 1MG TABLET in pregnant women.

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Breast Feeding

Caution

Consult your doctor, and there is no substantial research yet on the use of RAPACAN 1MG TABLET in breastfeeding/nursing mothers.

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Driving

Caution

Do not drive or operate machinery if you experience dizziness or drowsiness while using RAPACAN 1MG TABLET. RAPACAN 1MG TABLET can also sometimes cause dizziness/drowsiness; hence avoid driving in such situations. Seek medical attention if the symptoms persist longer.

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Liver

Caution

Please consult your doctor if you have any concerns regarding using RAPACAN 1MG TABLET in patients with liver impairment. Your doctor will prescribe only if the benefits outweigh the risks.

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Kidney

Caution

Please consult your doctor if you have any concerns regarding using RAPACAN 1MG TABLET in patients with kidney impairment. Your doctor will prescribe only if the benefits outweigh the risks.

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Children

Caution

There is limited information available on the use of RAPACAN 1MG TABLET in children. Please consult your doctor.

FAQs

RAPACAN 1MG TABLET is used to prevent organ rejection after a transplant.
RAPACAN 1MG TABLET contains Sirolimus is an immunosuppressant. It works by weakening your body's defence system (immune system) to help your body accept the new organ as if it were your own.
No, it is a prescribed drug given by a physician for preventing specific medical conditions. Taking it on your own can cause unwanted side effects.
RAPACAN 1MG TABLET is safe if used in the dose and duration recommended by your doctor. Take it exactly as directed, and do not skip any dose. Follow your doctor's guidelines carefully and inform your doctor if any of the side effects disturb you.
Please do not stop using RAPACAN 1MG TABLET without consulting your doctor on your own. Continue using RAPACAN 1MG TABLET for as long as your doctor has prescribed it to treat your condition effectually. Do not be reluctant to speak with your doctor if you experience any difficulty while taking RAPACAN 1MG TABLET.
Take the missed dose as soon as possible. However, skip the missed dose and return to your regular dosing schedule if it is time for the next dose.

Country of origin

INDIA

Manufacturer/Marketer address

20th KM, Hosur Road, Electronic City, Bangalore, India - 560 100
Other Info - RAP0002

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