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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
SiroRite Tablet is used to prevent organ rejection after a transplant. It contains Sirolimus which works by weakening the body's defence system (immune system) and assisting the body in accepting the new organ. In some cases, this medicine may cause side effects like abdominal pain, diarrhoea, headache, fever, urinary tract infection, anaemia, nausea, pain, and oedema.
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Composition :

SIROLIMUS-1MG

Manufacturer/Marketer :

Elera Pharma Ltd

Consume Type :

ORAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About SiroRite Tablet

SiroRite Tablet belongs to a class of drugs called 'immunosuppressants' used to prevent organ rejection after a transplant. Organ rejection occurs when a patient's immune system recognizes the donor organ as foreign and tries to eliminate it.

SiroRite Tablet contains Sirolimus is an immunosuppressant. It weakens your body's defence system (immune system) to help your body accept the new organ as if it were your own. Thereby preventing organ rejection in transplanted patients and assisting the body in accepting the new organ.

Use SiroRite Tablet as prescribed by your doctor. You are advised to use SiroRite Tablet for as long as your doctor has prescribed it based on your medical condition. Some people may experience abdominal pain, diarrhoea, headache, fever, urinary tract infection, anaemia, nausea, arthralgia, pain, and oedema. Most of these side effects of SiroRite Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

To treat your condition effectually, continue using SiroRite Tablet for as long as your doctor has prescribed it. Do not use SiroRite Tablet without a doctor's advice if you are allergic to SiroRite Tablet or other medicines. Consult your doctor before using SiroRite Tablet if you are pregnant or breastfeeding. Avoid alcohol consumption with SiroRite Tablet as it may increase the risk of severe adverse effects. Keep your doctor informed about your health condition and all the medicines you take before taking SiroRite Tablet to rule out any side effects.

Uses of SiroRite Tablet

Used to prevent organ rejection

Directions for Use

Swallow it as a whole with water; do not crush, break or chew it.

Medicinal Benefits

SiroRite Tablet contains Sirolimus is an immunosuppressant. It weakens your body's defence system (immune system) to help your body accept the new organ as if it were your own. Thereby preventing organ rejection in transplanted patients and assisting the body in accepting the new organ.

How SiroRite Tablet Works

SiroRite Tablet contains Sirolimus is an immunosuppressant. It weakens your body's defence system (immune system) to help your body accept the new organ as if it were your own. Thereby preventing organ rejection in transplanted patients and assisting the body in accepting the new organ.

Storage

Store in a cool and dry place away from sunlight

Side Effects of SiroRite Tablet

  • Peripheral oedema
  • Hypertriglyceridemia
  • Hypertension
  • Hypercholesterolemia
  • Creatinine increased
  • Abdominal pain
  • Diarrhoea
  • Headache
  • Fever
  • Urinary tract infection
  • Anaemia
  • Nausea
  • Arthralgia
  • Pain
  • Thrombocytopenia

What if I have taken an overdose of SiroRite Tablet

Take SiroRite Tablet only as prescribed by the physician. Do not exceed the recommended dose, as it might cause an overdose. If you suspect you have taken an overdose, seek immediate medical attention.

Drug Warnings

Therapeutic drug monitoring is required for all patients receiving SiroRite Tablet . To treat your condition effectually, continue using SiroRite Tablet for as long as your doctor has prescribed it. Do not use SiroRite Tablet without a doctor's advice if you are allergic to SiroRite Tablet or other medicines. Consult your doctor before using the SiroRite Tablet if you are pregnant or breastfeeding. Avoid alcohol consumption with SiroRite Tablet as it may increase the risk of severe adverse effects. Do not use SiroRite Tablet in more than prescribed doses or longer duration as it may cause adverse effects. And also, keep your doctor informed about your health condition and all the medicines you take before taking SiroRite Tablet to rule out any side effects.

Drug-Drug Interactions

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SirolimusCidofovir
Critical
SirolimusBCG vaccine
Critical

Drug-Drug Interactions

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SirolimusCidofovir
Critical
How does the drug interact with SiroRite Tablet 10's:
Co-administration of Cidofovir and SiroRite Tablet 10's can increase the risk or severity of Kidney problems.

How to manage the interaction:
Taking SiroRite Tablet 10's with Cidofovir is not recommended, but it can be taken together if prescribed by a doctor. However, if you experience nausea, vomiting, loss of hunger, increased or decreased urination, sudden weight gain or loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, or an irregular heart rhythm, consult a doctor. Do not discontinue any medications without consulting a doctor.
SirolimusBCG vaccine
Critical
How does the drug interact with SiroRite Tablet 10's:
Coadministration of SiroRite Tablet 10's with the BCG vaccine can make the vaccine less effective.

How to manage the interaction:
Taking SiroRite Tablet 10's with the BCG vaccine is not recommended, they can be taken together if advised by your doctor. However, contact your doctor if you experience any symptoms. Do not stop taking any medications without consulting a doctor.
SirolimusMifepristone
Critical
How does the drug interact with SiroRite Tablet 10's:
Coadministration of SiroRite Tablet 10's with Mifepristone can increase the levels of SiroRite Tablet 10's in the blood, which can increase the risk or severity of side effects.

How to manage the interaction:
Taking SiroRite Tablet 10's with Mifepristone is not recommended, they can be taken together if a doctor advises. However, contact a doctor if you experience any symptoms like back pain · difficulty falling asleep or staying asleep, fever, headache, joint pain, rash, stomach pain, constipation, or diarrhea. Do not stop taking any medications without consulting a doctor.
SirolimusPosaconazole
Critical
How does the drug interact with SiroRite Tablet 10's:
Coadministration of SiroRite Tablet 10's with posaconazole can lower the levels of SiroRite Tablet 10's in the blood.

How to manage the interaction:
Although there is an interaction between posaconazole with SiroRite Tablet 10's, they can be taken together if a doctor advises. However, if you experience any unusual symptoms contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
SirolimusVoriconazole
Critical
How does the drug interact with SiroRite Tablet 10's:
Coadministration of SiroRite Tablet 10's and Voriconazole can increase blood levels and side effects of Voriconazole.

How to manage the interaction:
Taking Voriconazole with SiroRite Tablet 10's is generally avoided as it can result in an interaction, please consult a doctor before taking it. Contact a doctor if you experience nausea, fever, abdominal pain, or yellowing of the skin or eyes. Do not stop using any medication without consulting a doctor.
SirolimusIndometacin
Severe
How does the drug interact with SiroRite Tablet 10's:
Co-administration of Indomethacin with SiroRite Tablet 10's can increase the risk or severity of kidney damage.

How to manage the interaction:
Although taking Indometacin and SiroRite Tablet 10's together can possibly result in an interaction, it can be taken if a doctor has prescribed it. However, consult a doctor immediately, if you experience nausea, vomiting, decreased hunger, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, breathing difficulty, muscle cramps, dizziness, confusion, and irregular heart rhythm. Do not discontinue any medication without consulting a doctor.
SirolimusLeflunomide
Severe
How does the drug interact with SiroRite Tablet 10's:
Co-administration of SiroRite Tablet 10's with Leflunomide can increase the risk or severity of developing serious infections.

How to manage the interaction:
Although taking SiroRite Tablet 10's and Leflunomide together can evidently cause an interaction, it can be taken if a doctor has suggested it. However, if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning sensation when you urinate, consult a doctor. Do not stop using any medications without a doctor's advice.
SirolimusPhenytoin
Severe
How does the drug interact with SiroRite Tablet 10's:
Co-administration of SiroRite Tablet 10's and Phenytoin can reduce the blood levels and effectiveness of SiroRite Tablet 10's.

How to manage the interaction:
Although there is a possible interaction between Phenytoin and SiroRite Tablet 10's, they can be taken together if a doctor has prescribed it. Do not stop using any medications without talking to a doctor.
SirolimusSulindac
Severe
How does the drug interact with SiroRite Tablet 10's:
Coadministration of Sulindac and SiroRite Tablet 10's can increase the risk or severity of kidney problems.

How to manage the interaction:
Although taking SiroRite Tablet 10's and Sulindac together can evidently cause an interaction, it can be taken if a doctor has suggested it. However, if you experience nausea, vomiting, a decrease in hunger, increased or decreased urine, weight gain or loss that occurs suddenly, fluid retention, swelling, difficulty breathing, muscle pain, fatigue, weakness, dizziness, confusion, and irregular heartbeat, consult a doctor. Do not discontinue any medications without a doctor's advice.
SirolimusHuman immunoglobulin
Severe
How does the drug interact with SiroRite Tablet 10's:
Co-administration of Human immunoglobulin and SiroRite Tablet 10's may raise the risk or severity of kidney problems.

How to manage the interaction:
Although taking Human immunoglobulin and SiroRite Tablet 10's together can cause an interaction, it can be taken if a doctor has suggested it. However, if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, or an irregular heart rhythm, consult a doctor. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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SIROLIMUS-1MGGrapefruit and Grapefruit Juice
Moderate

Drug-Food Interactions

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SIROLIMUS-1MGGrapefruit and Grapefruit Juice
Moderate
Common Foods to Avoid:
Grapefruit Juice, Grapefruit

How to manage the interaction:
Taking SiroRite Tablet 10's with Grapefruit and Grapefruit juice may increase the side effects of SiroRite Tablet 10's. Avoid or limit consumption of Grapefruit and Grapefruit juice while taking SiroRite Tablet 10's.

Habit Forming

No

Therapeutic Class

IMMUNOSUPPRESSANTS

SiroRite Tablet Substitute

Substitutes safety advice
  • Siromus Tablet 6's

    by AYUR

    159.15per tablet
  • Rapasim Tablet 10's

    133.11per tablet
  • RAPACAN 1MG TABLET

    244.02per tablet
  • Raparen 1 Tablet 10's

    155.79per tablet
  • SIROPAN TABLET

    207.32per tablet
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Alcohol

Caution

It is advised to avoid alcohol intake since it may worsen the side effects.

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Pregnancy

Caution

Consult your doctor, and there is no substantial research yet on the use of SiroRite Tablet in pregnant women.

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Breast Feeding

Caution

Consult your doctor, and there is no substantial research yet on the use of SiroRite Tablet in breastfeeding/nursing mothers.

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Driving

Caution

Do not drive or operate machinery if you experience dizziness or drowsiness while using SiroRite Tablet . SiroRite Tablet can also sometimes cause dizziness/drowsiness; hence avoid driving in such situations. Seek medical attention if the symptoms persist longer.

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Liver

Caution

Please consult your doctor if you have any concerns regarding using SiroRite Tablet in patients with liver impairment. Your doctor will prescribe only if the benefits outweigh the risks.

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Kidney

Caution

Please consult your doctor if you have any concerns regarding using SiroRite Tablet in patients with kidney impairment. Your doctor will prescribe only if the benefits outweigh the risks.

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Children

Caution

There is limited information available on the use of SiroRite Tablet in children. Please consult your doctor.

FAQs

SiroRite Tablet is used to prevent organ rejection after a transplant.
SiroRite Tablet contains Sirolimus is an immunosuppressant. It works by weakening your body's defence system (immune system) to help your body accept the new organ as if it were your own.
No, it is a prescribed drug given by a physician for preventing specific medical conditions. Taking it on your own can cause unwanted side effects.
SiroRite Tablet is safe if used in the dose and duration recommended by your doctor. Take it exactly as directed, and do not skip any dose. Follow your doctor's guidelines carefully and inform your doctor if any of the side effects disturb you.
Please do not stop using SiroRite Tablet without consulting your doctor on your own. Continue using SiroRite Tablet for as long as your doctor has prescribed it to treat your condition effectually. Do not be reluctant to speak with your doctor if you experience any difficulty while taking SiroRite Tablet .
Take the missed dose as soon as possible. However, skip the missed dose and return to your regular dosing schedule if it is time for the next dose.

Country of origin

India

Manufacturer/Marketer address

D.No. 1-13-140/186, Dr.As. Rao Nagar, Ecil, Kapra Municipality, Secunderabed-500062, A.P
Other Info - SIR0047

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