apollo
0
Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Raparen 1 Tablet is used to prevent organ rejection after a transplant. It contains Sirolimus which works by weakening the body's defence system (immune system) and assisting the body in accepting the new organ. In some cases, this medicine may cause side effects like abdominal pain, diarrhoea, headache, fever, urinary tract infection, anaemia, nausea, pain, and oedema.
Read more
rxMedicinePrescription drug

Whats That

tooltip

Composition :

SIROLIMUS-1MG

Manufacturer/Marketer :

La Renon Healthcare Pvt Ltd

Consume Type :

ORAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Raparen 1 Tablet

Raparen 1 Tablet belongs to a class of drugs called 'immunosuppressants' used to prevent organ rejection after a transplant. Organ rejection occurs when a patient's immune system recognizes the donor organ as foreign and tries to eliminate it.

Raparen 1 Tablet contains Sirolimus is an immunosuppressant. It weakens your body's defence system (immune system) to help your body accept the new organ as if it were your own. Thereby preventing organ rejection in transplanted patients and assisting the body in accepting the new organ.

Use Raparen 1 Tablet as prescribed by your doctor. You are advised to use Raparen 1 Tablet for as long as your doctor has prescribed it based on your medical condition. Some people may experience abdominal pain, diarrhoea, headache, fever, urinary tract infection, anaemia, nausea, arthralgia, pain, and oedema. Most of these side effects of Raparen 1 Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

To treat your condition effectually, continue using Raparen 1 Tablet for as long as your doctor has prescribed it. Do not use Raparen 1 Tablet without a doctor's advice if you are allergic to Raparen 1 Tablet or other medicines. Consult your doctor before using Raparen 1 Tablet if you are pregnant or breastfeeding. Avoid alcohol consumption with Raparen 1 Tablet as it may increase the risk of severe adverse effects. Keep your doctor informed about your health condition and all the medicines you take before taking Raparen 1 Tablet to rule out any side effects.

Uses of Raparen 1 Tablet

Used to prevent organ rejection

Directions for Use

Swallow it as a whole with water; do not crush, break or chew it.

Medicinal Benefits

Raparen 1 Tablet contains Sirolimus is an immunosuppressant. It weakens your body's defence system (immune system) to help your body accept the new organ as if it were your own. Thereby preventing organ rejection in transplanted patients and assisting the body in accepting the new organ.

How Raparen 1 Tablet Works

Raparen 1 Tablet contains Sirolimus is an immunosuppressant. It weakens your body's defence system (immune system) to help your body accept the new organ as if it were your own. Thereby preventing organ rejection in transplanted patients and assisting the body in accepting the new organ.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Raparen 1 Tablet

  • Peripheral oedema
  • Hypertriglyceridemia
  • Hypertension
  • Hypercholesterolemia
  • Creatinine increased
  • Abdominal pain
  • Diarrhoea
  • Headache
  • Fever
  • Urinary tract infection
  • Anaemia
  • Nausea
  • Arthralgia
  • Pain
  • Thrombocytopenia

What if I have taken an overdose of Raparen 1 Tablet

Take Raparen 1 Tablet only as prescribed by the physician. Do not exceed the recommended dose, as it might cause an overdose. If you suspect you have taken an overdose, seek immediate medical attention.

Drug Warnings

Therapeutic drug monitoring is required for all patients receiving Raparen 1 Tablet . To treat your condition effectually, continue using Raparen 1 Tablet for as long as your doctor has prescribed it. Do not use Raparen 1 Tablet without a doctor's advice if you are allergic to Raparen 1 Tablet or other medicines. Consult your doctor before using the Raparen 1 Tablet if you are pregnant or breastfeeding. Avoid alcohol consumption with Raparen 1 Tablet as it may increase the risk of severe adverse effects. Do not use Raparen 1 Tablet in more than prescribed doses or longer duration as it may cause adverse effects. And also, keep your doctor informed about your health condition and all the medicines you take before taking Raparen 1 Tablet to rule out any side effects.

Drug-Drug Interactions

verifiedApollotooltip
SirolimusBCG vaccine
Critical
SirolimusPosaconazole
Critical

Drug-Drug Interactions

Login/Sign Up

SirolimusBCG vaccine
Critical
How does the drug interact with Raparen 1 Tablet 10's:
Coadministration of Raparen 1 Tablet 10's with the BCG vaccine can make the vaccine less effective.

How to manage the interaction:
Taking Raparen 1 Tablet 10's with the BCG vaccine is not recommended, they can be taken together if advised by your doctor. However, contact your doctor if you experience any symptoms. Do not stop taking any medications without consulting a doctor.
SirolimusPosaconazole
Critical
How does the drug interact with Raparen 1 Tablet 10's:
Coadministration of Raparen 1 Tablet 10's with posaconazole can lower the levels of Raparen 1 Tablet 10's in the blood.

How to manage the interaction:
Although there is an interaction between posaconazole with Raparen 1 Tablet 10's, they can be taken together if a doctor advises. However, if you experience any unusual symptoms contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
SirolimusMifepristone
Critical
How does the drug interact with Raparen 1 Tablet 10's:
Coadministration of Raparen 1 Tablet 10's with Mifepristone can increase the levels of Raparen 1 Tablet 10's in the blood, which can increase the risk or severity of side effects.

How to manage the interaction:
Taking Raparen 1 Tablet 10's with Mifepristone is not recommended, they can be taken together if a doctor advises. However, contact a doctor if you experience any symptoms like back pain · difficulty falling asleep or staying asleep, fever, headache, joint pain, rash, stomach pain, constipation, or diarrhea. Do not stop taking any medications without consulting a doctor.
SirolimusCidofovir
Critical
How does the drug interact with Raparen 1 Tablet 10's:
Co-administration of Cidofovir and Raparen 1 Tablet 10's can increase the risk or severity of Kidney problems.

How to manage the interaction:
Taking Raparen 1 Tablet 10's with Cidofovir is not recommended, but it can be taken together if prescribed by a doctor. However, if you experience nausea, vomiting, loss of hunger, increased or decreased urination, sudden weight gain or loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, or an irregular heart rhythm, consult a doctor. Do not discontinue any medications without consulting a doctor.
SirolimusVoriconazole
Critical
How does the drug interact with Raparen 1 Tablet 10's:
Coadministration of Raparen 1 Tablet 10's and Voriconazole can increase blood levels and side effects of Voriconazole.

How to manage the interaction:
Taking Voriconazole with Raparen 1 Tablet 10's is generally avoided as it can result in an interaction, please consult a doctor before taking it. Contact a doctor if you experience nausea, fever, abdominal pain, or yellowing of the skin or eyes. Do not stop using any medication without consulting a doctor.
SirolimusLithium
Severe
How does the drug interact with Raparen 1 Tablet 10's:
Coadministration of Raparen 1 Tablet 10's with Lithium together may increase the risk or severity of kidney problems.

How to manage the interaction:
Although taking Lithium and Raparen 1 Tablet 10's together can cause an interaction, it can be taken if a doctor has suggested it. However, consult the doctor immediately if you experience symptoms such as nausea, vomiting, loss of hunger, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. Do not discontinue any medications without consulting a doctor.
SirolimusEtanercept
Severe
How does the drug interact with Raparen 1 Tablet 10's:
Coadministration of Etanercept with Raparen 1 Tablet 10's, may increase the risk or severity of developing serious infection.

How to manage the interaction:
Although there is a possible interaction between Raparen 1 Tablet 10's and Etanercept, you can take these medicines together if prescribed by a doctor. However, if you develop fever, chills, diarrhea, sore throat, muscular pains, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning during urination, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
SirolimusPolymyxin b
Severe
How does the drug interact with Raparen 1 Tablet 10's:
Co-administration of Raparen 1 Tablet 10's and Polymyxin B together may increase the risk or severity of kidney problems.

How to manage the interaction:
There may be a possibility of interaction between Raparen 1 Tablet 10's and Polymyxin b, but it can be taken if prescribed by a doctor. However, if you experience nausea, vomiting, a decrease in hunger, increased or decreased urine, weight gain or loss that occurs suddenly, fluid retention, swelling, difficulty breathing, bone pain, muscle pain, fatigue, weakness, dizziness, confusion, and irregular heartbeat, consult a doctor. Do not discontinue any medications without a doctor's advice.
SirolimusCapreomycin
Severe
How does the drug interact with Raparen 1 Tablet 10's:
Co-administration of Capreomycin and Raparen 1 Tablet 10's together can increase the risk or severity of kidney problems.

How to manage the interaction:
Although taking Raparen 1 Tablet 10's and Capreomycin together can evidently cause an interaction, but it can be taken if a doctor has suggested it. However, if you experience nausea, vomiting, a decrease in hunger, increased or decreased urine, weight gain or loss that occurs suddenly, fluid retention, swelling, difficulty breathing, muscle pain, fatigue, weakness, dizziness, confusion, and irregular heartbeat, consult a doctor. Do not discontinue any medications without a doctor's advice.
SirolimusVancomycin
Severe
How does the drug interact with Raparen 1 Tablet 10's:
Coadministration of Vancomycin with Raparen 1 Tablet 10's can increase the risk or severity of kidney problems.

How to manage the interaction:
Taking Vancomycin with Raparen 1 Tablet 10's may result in an interaction, they can be taken together if prescribed by a doctor. However, contact a doctor immediately if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. Do not discontinue any medication without consulting a doctor.

Drug-Food Interactions

verifiedApollotooltip
SIROLIMUS-1MGGrapefruit and Grapefruit Juice
Moderate

Drug-Food Interactions

Login/Sign Up

SIROLIMUS-1MGGrapefruit and Grapefruit Juice
Moderate
Common Foods to Avoid:
Grapefruit Juice, Grapefruit

How to manage the interaction:
Taking Raparen 1 Tablet 10's with Grapefruit and Grapefruit juice may increase the side effects of Raparen 1 Tablet 10's. Avoid or limit consumption of Grapefruit and Grapefruit juice while taking Raparen 1 Tablet 10's.

Habit Forming

No

Therapeutic Class

IMMUNOSUPPRESSANTS

Raparen 1 Tablet Substitute

Substitutes safety advice
  • Siromus Tablet 6's

    by AYUR

    159.15per tablet
  • Rapasim Tablet 10's

    146.39per tablet
  • RAPACAN 1MG TABLET

    244.02per tablet
  • SIROPAN TABLET

    207.32per tablet
  • ROCAS TABLET

    19.20per tablet
bannner image

Alcohol

Caution

It is advised to avoid alcohol intake since it may worsen the side effects.

bannner image

Pregnancy

Caution

Consult your doctor, and there is no substantial research yet on the use of Raparen 1 Tablet in pregnant women.

bannner image

Breast Feeding

Caution

Consult your doctor, and there is no substantial research yet on the use of Raparen 1 Tablet in breastfeeding/nursing mothers.

bannner image

Driving

Caution

Do not drive or operate machinery if you experience dizziness or drowsiness while using Raparen 1 Tablet . Raparen 1 Tablet can also sometimes cause dizziness/drowsiness; hence avoid driving in such situations. Seek medical attention if the symptoms persist longer.

bannner image

Liver

Caution

Please consult your doctor if you have any concerns regarding using Raparen 1 Tablet in patients with liver impairment. Your doctor will prescribe only if the benefits outweigh the risks.

bannner image

Kidney

Caution

Please consult your doctor if you have any concerns regarding using Raparen 1 Tablet in patients with kidney impairment. Your doctor will prescribe only if the benefits outweigh the risks.

bannner image

Children

Caution

There is limited information available on the use of Raparen 1 Tablet in children. Please consult your doctor.

FAQs

Raparen 1 Tablet is used to prevent organ rejection after a transplant.
Raparen 1 Tablet contains Sirolimus is an immunosuppressant. It works by weakening your body's defence system (immune system) to help your body accept the new organ as if it were your own.
No, it is a prescribed drug given by a physician for preventing specific medical conditions. Taking it on your own can cause unwanted side effects.
Raparen 1 Tablet is safe if used in the dose and duration recommended by your doctor. Take it exactly as directed, and do not skip any dose. Follow your doctor's guidelines carefully and inform your doctor if any of the side effects disturb you.
Please do not stop using Raparen 1 Tablet without consulting your doctor on your own. Continue using Raparen 1 Tablet for as long as your doctor has prescribed it to treat your condition effectually. Do not be reluctant to speak with your doctor if you experience any difficulty while taking Raparen 1 Tablet .
Take the missed dose as soon as possible. However, skip the missed dose and return to your regular dosing schedule if it is time for the next dose.

Country of origin

India

Manufacturer/Marketer address

Behind Rajpath Club, Kensville Road, Opp. Infostretch Building, Off S.G. Highway, Ahmedabad- 380059, Gujarat- India
Other Info - RAP0162

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
whatsapp Floating Button

Add to Cart