Siromus Tablet belongs to a class of drugs called 'immunosuppressants' used to prevent organ rejection after a transplant. Organ rejection occurs when a patient's immune system recognizes the donor organ as foreign and tries to eliminate it.

Siromus Tablet contains Sirolimus is an immunosuppressant. It weakens your body's defence system (immune system) to help your body accept the new organ as if it were your own. Thereby preventing organ rejection in transplanted patients and assisting the body in accepting the new organ.

Use Siromus Tablet as prescribed by your doctor. You are advised to use Siromus Tablet for as long as your doctor has prescribed it based on your medical condition. Some people may experience abdominal pain, diarrhoea, headache, fever, urinary tract infection, anaemia, nausea, arthralgia, pain, and oedema. Most of these side effects of Siromus Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

To treat your condition effectually, continue using Siromus Tablet for as long as your doctor has prescribed it. Do not use Siromus Tablet without a doctor's advice if you are allergic to Siromus Tablet or other medicines. Consult your doctor before using Siromus Tablet if you are pregnant or breastfeeding. Avoid alcohol consumption with Siromus Tablet as it may increase the risk of severe adverse effects. Keep your doctor informed about your health condition and all the medicines you take before taking Siromus Tablet to rule out any side effects.

Siromus Tablet contains Sirolimus is an immunosuppressant. It weakens your body's defence system (immune system) to help your body accept the new organ as if it were your own. Thereby preventing organ rejection in transplanted patients and assisting the body in accepting the new organ.

• Peripheral oedema
• Hypertriglyceridemia
• Hypertension
• Hypercholesterolemia
• Creatinine increased
• Abdominal pain
• Diarrhoea
• Headache
• Fever
• Urinary tract infection
• Anaemia
• Nausea
• Arthralgia
• Pain
• Thrombocytopenia

Therapeutic drug monitoring is required for all patients receiving Siromus Tablet. To treat your condition effectually, continue using Siromus Tablet for as long as your doctor has prescribed it. Do not use Siromus Tablet without a doctor's advice if you are allergic to Siromus Tablet or other medicines. Consult your doctor before using the Siromus Tablet if you are pregnant or breastfeeding. Avoid alcohol consumption with Siromus Tablet as it may increase the risk of severe adverse effects. Do not use Siromus Tablet in more than prescribed doses or longer duration as it may cause adverse effects. And also, keep your doctor informed about your health condition and all the medicines you take before taking Siromus Tablet to rule out any side effects.

Drug-Drug Interactions: Siromus Tablet may interact with other immunosuppressive agents (e.g. mycophenolate mofetil, mycophenolic acid), antihistamines (e.g. loratadine), anti-hypertensive medicines (e.g. losartan), and diabetic medicines (e.g. insulin glargine, insulin aspart). The relevance of a particular drug interaction varies from person to person. Always consult your healthcare provider before starting or stopping any medication, and also inform your doctor of all your medical conditions and ongoing therapies before prescribing this medication. Considering these, your doctor may check the drug interactions before prescribing this medication.

Drug-Food Interactions: Avoid consumption of alcohol, eating grapefruit or drinking grapefruit juice while you are taking Siromus Tablet.

Drug-Disease Interactions: Brief your doctor if you have a medical history of allergic reactions to medicines, Infections, PML (progressive multifocal leukoencephalopathy), angioedema, hyperlipidemia, liver disease, liver transplantation, lung dysfunction, lung transplant, renal dysfunction before taking Siromus Tablet.

• MYCOPHENOLATE MOFETIL
• MYCOPHENOLIC ACID
• LORATADINE
• LOSARTAN
• INSULIN ASPART
• INSULIN GLARGINE

Organ rejection occurs when a patient’s immune system recognizes the donor organ as foreign and tries to eliminate it.