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Written By Veda Maddala , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy
Ketomac 200 Tablet 10's is an antifungal medicine used in the treatment of fungal infections such as blastomycosis, coccidioidomycosis, paracoccidioidomycosis, and histoplasmosis (lung infection caused by Histoplasma fungus). This medicine works by inhibiting the growth and multiplication of fungal cells that are responsible for the growth of infection-causing fungi.
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Whats That

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Composition :

KETOCONAZOLE-200MG

Manufacturer/Marketer :

Torque Pharmaceuticals Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

About Ketomac 200 Tablet 10's

Ketomac 200 Tablet 10's belongs to a class of drugs called antifungals indicated to treat various systemic fungal infections such as blastomycosis (infection caused by Blastomyces fungus), chromomycosis (chronic infection of the skin and subcutaneous tissue), Coccidioidomycosis (infection caused by Coccidioides fungus), paracoccidioidomycosis (infection caused by Paracoccidioides fungus) and histoplasmosis (lung infection caused by Histoplasma fungus). It is used only when other effective antifungal therapies are not available or tolerated and if potential benefits outweigh potential risks.

Ketomac 200 Tablet 10's contains Ketoconazole which works by destroying fungal cell membranes that are essential for their survival as they prevent the entry of unwanted substances into the cells and stop the leakage of cell contents. Thus, kills fungi and treats the fungal infection.

Take Ketomac 200 Tablet 10's as prescribed. Your doctor will advise you on how often you need to take Ketomac 200 Tablet 10's based on your medical condition. Some people may experience headache, nausea, stomach pain, and diarrhoea. Most of these side effects of Ketomac 200 Tablet 10's do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor. 

If you are allergic to Ketoconazole or any other medicines, please tell your doctor. If you are pregnant or planning for pregnancy, inform your doctor before taking Ketomac 200 Tablet 10's. Avoid breastfeeding while taking Ketomac 200 Tablet 10's as it may be excreted in breast milk. You are recommended to avoid alcohol consumption whilst on treatment with Ketomac 200 Tablet 10's. Ketomac 200 Tablet 10's is not recommended for children below 2 years of age. For children above 2 years, it is recommended to use only if the doctor has determined that the benefits outweigh the risks.

Uses of Ketomac 200 Tablet 10's

Treatment of Systemic fungal infections

Directions for Use

Take Ketomac 200 Tablet 10's with food to avoid stomach upset or take it as advised by the doctor. Swallow the whole tablet/capsule with a glass of water. Do not break, crush or chew it.

Medicinal Benefits

Ketomac 200 Tablet 10's is an antifungal used to treat severe fungal infections. It is used only when other effective antifungal therapies are not available or tolerated and if potential benefits outweigh potential risks. It destroys fungal cell membranes that are essential for their survival as they prevent the entry of unwanted substances into the cells and stop the leakage of cell contents. Thus, kills fungi and treats the fungal infection.

How Ketomac 200 Tablet 10's Works

Ketomac 200 Tablet 10's contains Ketoconazole which works by destroying fungal cell membranes that are essential for their survival as they prevent the entry of unwanted substances into the cells and stop the leakage of cell contents. Thus, kills fungi and treats the fungal infection.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Ketomac 200 Tablet 10's

  • Headache
  • Nausea
  • Stomach pain
  • Diarrhoea 

What if I have taken an overdose of Ketomac 200 Tablet 10's

Never take more than the prescribed dose. When Ketomac 200 Tablet 10's is used at high doses, it may, though unlikely, result in decreased testosterone levels, sperm production, and an issue with the adrenal glands (adrenal insufficiency). Seek emergency medical help if an overdose is suspected.

Drug Warnings

If you are allergic to Ketoconazole or any other medicines, please tell your doctor. If you are pregnant or planning for pregnancy, inform your doctor before taking Ketomac 200 Tablet 10's. Avoid breastfeeding while taking Ketomac 200 Tablet 10's as it may be excreted in breast milk. You are recommended to avoid alcohol consumption with Ketomac 200 Tablet 10's. If you have a loss of appetite, tiredness, stomach pain, vomiting, yellowing of skin or eyes, dark urine, or light-coloured stools, inform your doctor immediately as they might be symptoms of hepatotoxicity (liver damage). 

Drug-Drug Interactions

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KetoconazoleAlfuzosin
Critical
KetoconazoleMethadone
Critical

Drug-Drug Interactions

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KetoconazoleAlfuzosin
Critical
How does the drug interact with Ketomac 200 Tablet:
Using alfuzosin together with Ketomac 200 Tablet may significantly increase the blood levels of alfuzosin, which may result in side effects.

How to manage the interaction:
Taking Alfuzosin with Ketomac 200 Tablet is not recommended as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience fainting, headache, flushing, nasal congestion, or heart palpitation, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
KetoconazoleMethadone
Critical
How does the drug interact with Ketomac 200 Tablet:
When Methadone is taken with Ketomac 200 Tablet, it can increase the risk of serious side effects such as respiratory problems, low blood pressure, irregular heart rhythm.

How to manage the interaction:
Taking Ketomac 200 Tablet with Methadone is not recommended as it can cause an interaction, it can be taken if prescribed by the doctor. However, if you experience breathing difficulty, fainting, heart palpitations, consult the doctor immediately. Do not discontinue any medication without consulting a doctor.
KetoconazoleMidazolam
Critical
How does the drug interact with Ketomac 200 Tablet:
Co-administration of Ketomac 200 Tablet and Midazolam may increase the risk of side effects.

How to manage the interaction:
Although taking Ketomac 200 Tablet and Midazolam together is not recommended as it may result in an interaction, they can be taken if prescribed by a doctor. Consult a doctor if you have excessive or prolonged sleepiness and breathing issues. Do not discontinue any medication without consulting a doctor.
KetoconazoleTriazolam
Critical
How does the drug interact with Ketomac 200 Tablet:
When Triazolam is taken with Ketomac 200 Tablet, it can increase the risk of drowsiness and slowed breathing.

How to manage the interaction:
Taking Triazolam with Ketomac 200 Tablet is not recommended as it can cause an interaction, it can be taken if prescribed by the doctor. Do not stop using any medications without talking to a doctor.
KetoconazoleColchicine
Critical
How does the drug interact with Ketomac 200 Tablet:
Using colchicine together with Ketomac 200 Tablet may increase the blood levels of colchicine, increasing the risk of serious side effects.

How to manage the interaction:
Although taking Ketomac 200 Tablet with Colchicine is not recommended as it can cause an interaction, they can be taken if prescribed by a doctor. However, contact a doctor if you experience abdominal pain, nausea, vomiting, diarrhea, fever, muscle pain, weakness, fatigue, and/or numbness or tingling in your hands and feet. Do not stop using any medications without consulting a doctor
KetoconazoleHalofantrine
Critical
How does the drug interact with Ketomac 200 Tablet:
Using Ketomac 200 Tablet with Halofantrine can increase the chance of a serious abnormal heart rhythm.

How to manage the interaction:
Taking Ketomac 200 Tablet with Halofantrine is not recommended as it can cause an interaction, it can be taken if prescribed by the doctor. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not stop any medications without a doctor's advice.
KetoconazoleVoclosporin
Critical
How does the drug interact with Ketomac 200 Tablet:
When Voclosporin is taken with Ketomac 200 Tablet, it can increase the risk of serious side effects.

How to manage the interaction:
Taking Ketomac 200 Tablet with Voclosporin is not recommended, it can be taken if prescribed by the doctor. However, if you experience any unusual symptoms, consult the doctor immediately.
KetoconazoleNisoldipine
Critical
How does the drug interact with Ketomac 200 Tablet:
When Nisoldipine is taken with Ketomac 200 Tablet, it can increase the blood levels of Nimodipine which may lead to serious side effects (irregular heart rhythm, fluid retention, swelling, and extremely low blood pressure).

How to manage the interaction:
Taking Ketomac 200 Tablet with Nisoldipine can cause an interaction, but it can be taken if prescribed by the doctor. However, if you experience irregular heart rhythm, fluid retention, swelling, and extremely low blood pressure while using these medications, consult the doctor. Do not stop using any medications without talking to a doctor.
KetoconazoleLovastatin
Critical
How does the drug interact with Ketomac 200 Tablet:
Coadministration of Lovastatin with Ketomac 200 Tablet can increase the risk of liver damage, rhabdomyolysis (the breakdown of skeletal muscle tissue) which may lead to kidney damage.

How to manage the interaction:
Taking Ketomac 200 Tablet with Lovastatin is not recommended as it can cause an interaction, it can be taken if a doctor has advised it. However, if you experience symptoms like unexplained muscular pain, tenderness, weakness, accompanied by fever, dark urine or unexpected bruising or bleeding, skin rash, itching, vomiting, yellowing of the skin or eyes, chills, joint pain, swelling, consult a doctor immediately. Do not discontinue any medication without consulting a doctor.
KetoconazoleIrinotecan
Critical
How does the drug interact with Ketomac 200 Tablet:
Using irinotecan together with Ketomac 200 Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Ketomac 200 Tablet with Irinotecan is not recommended as it can cause an interaction, but it can be taken if prescribed by the doctor. However, if you experience any symptoms such as paleness, fatigue, dizziness, fainting, unexpected bruising or bleeding, fever, chills, diarrhea, sore throat, muscle aches, breathing difficulty, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination, consult the doctor immediately.

Drug-Food Interactions

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KETOCONAZOLE-200MGGrapefruit and Grapefruit Juice
Moderate

Drug-Food Interactions

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KETOCONAZOLE-200MGGrapefruit and Grapefruit Juice
Moderate
Common Foods to Avoid:
Grapefruit Juice, Grapefruit

How to manage the interaction:
Consumption of grapefruit or its juice with Ketomac 200 Tablet may result in side effects such as joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of hunger, dark urine, light colored stools, and yellowing of the skin or eyes. Avoid consuming grapefruit, grapefruit juice, or any supplements that include grapefruit extract while taking Ketomac 200 Tablet.

Diet & Lifestyle Advise

  • Avoid high-risk areas such as renovated buildings, construction sites, pigeon or chick coops, and caves.
  • Wear a respiratory mask when there is a risk of exposure to spores.
  • People with a weak immune system are advised to avoid activities that involve close contact with dust or dirt including digging, yard work, and gardening.
  • Close windows and stay inside during dust storms.
  • Clean skin injuries well with soap and water to reduce the risk of developing a skin infection.

Habit Forming

No

Therapeutic Class

ANTIFUNGALS - ORAL

Ketomac 200 Tablet 10's Substitute

Substitutes safety advice
  • Fungicide Tablet 10's

    by Others

    47.52per tablet
  • Phytoral Tablet 10's

    by Others

    46.08per tablet
  • Kenz Tablet 10's

    by AYUR

    20.25per tablet
  • Hyphoral Tablet 10's

    by Others

    34.61per tablet
  • Ketocip 200 mg Tablet 10's

    by Others

    21.78per tablet
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Alcohol

Unsafe

Avoid consumption of alcohol while taking Ketomac 200 Tablet 10's as it may increase the risk of liver damage and cause adverse effects.

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Pregnancy

Caution

Ketomac 200 Tablet 10's is a Category C pregnancy drug and is given to pregnant women only if the doctor thinks the benefits outweigh the risks.

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Breast Feeding

Unsafe

Ketomac 200 Tablet 10's may be excreted in breast milk. Therefore, it is recommended to avoid breastfeeding while taking Ketomac 200 Tablet 10's.

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Driving

Caution

Ketomac 200 Tablet 10's may cause dizziness or drowsiness. Therefore, drive only if you alert after taking Ketomac 200 Tablet 10's.

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Liver

Unsafe

Ketomac 200 Tablet 10's is contraindicated in patients with chronic or acute liver disease. Therefore, inform your doctor if you have any Liver diseases/conditions.

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Kidney

Caution

If you have any concerns regarding the use of Ketomac 200 Tablet 10's in patients with kiver diseases/conditions, consult a doctor.

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Children

Caution

Ketomac 200 Tablet 10's is not recommended for children below 2 years of age. For children above 2 years, it is recommended to use only if the doctor has determined that benefits outweigh risks.

FAQs

Ketomac 200 Tablet 10's belongs to a class of drugs called antifungals indicated to treat various systemic fungal infections such as blastomycosis (infection caused by Blastomyces fungus), chromomycosis (chronic infection of the skin and subcutaneous tissue), Coccidioidomycosis (infection caused by Coccidioides fungus), paracoccidioidomycosis (infection caused by Paracoccidioides fungus) and histoplasmosis (lung infection caused by Histoplasma fungus).

Ketomac 200 Tablet 10's works by destroying fungal cell membranes that are essential for their survival as they prevent the entry of unwanted substances into the cells and stop the leakage of cell contents. Thus, kills fungi and treats the fungal infection.

Ketomac 200 Tablet 10's is not recommended to treat fungal meningitis (fungal infection spreads to the brain and spinal cord) as it poorly penetrates into the cerebrospinal fluid. Therefore, inform your doctor if you have fungal meningitis so that appropriate medication may be prescribed.

You are recommended to avoid foods containing chocolate and caffeine such as cocoa beans, tea, coffee, cola and energy drinks while taking Ketomac 200 Tablet 10's as it may increase the adverse effects of caffeine such as drowsiness, nervousness or nausea.

You are not recommended to take Ketomac 200 Tablet 10's with simvastatin (lipid-lowering drug) as co-administration of these medicines may cause muscle problems. Therefore, please consult a doctor before taking Ketomac 200 Tablet 10's with other medicines.

No, you are not recommended to stop taking Ketomac 200 Tablet 10's without consulting your doctor as it may cause recurring infection. Therefore, take Ketomac 200 Tablet 10's for as long as your doctor has prescribed it and if you experience any difficulty while taking Ketomac 200 Tablet 10's, please consult your doctor.

Country of origin

India

Manufacturer/Marketer address

232-33-34, Sector 34-A, Chandigarh, India
Other Info - KET0526

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