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Written By Veda Maddala , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy
Last Updated Oct 9, 2024 | 12:36 PM IST
Denon Tablet is an antifungal medicine used in the treatment of fungal infections such as blastomycosis, coccidioidomycosis, paracoccidioidomycosis, and histoplasmosis (lung infection caused by Histoplasma fungus). This medicine works by inhibiting the growth and multiplication of fungal cells that are responsible for the growth of infection-causing fungi.
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Prescription drug

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Composition :

KETOCONAZOLE-200MG

Consume Type :

ORAL

Return Policy :

Not Returnable

About Denon Tablet

Denon Tablet belongs to a class of drugs called antifungals indicated to treat various systemic fungal infections such as blastomycosis (infection caused by Blastomyces fungus), chromomycosis (chronic infection of the skin and subcutaneous tissue), Coccidioidomycosis (infection caused by Coccidioides fungus), paracoccidioidomycosis (infection caused by Paracoccidioides fungus) and histoplasmosis (lung infection caused by Histoplasma fungus). It is used only when other effective antifungal therapies are not available or tolerated and if potential benefits outweigh potential risks.

Denon Tablet contains Ketoconazole which works by destroying fungal cell membranes that are essential for their survival as they prevent the entry of unwanted substances into the cells and stop the leakage of cell contents. Thus, kills fungi and treats the fungal infection.

Take Denon Tablet as prescribed. Your doctor will advise you on how often you need to take Denon Tablet based on your medical condition. Some people may experience headache, nausea, stomach pain, and diarrhoea. Most of these side effects of Denon Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor. 

If you are allergic to Ketoconazole or any other medicines, please tell your doctor. If you are pregnant or planning for pregnancy, inform your doctor before taking Denon Tablet. Avoid breastfeeding while taking Denon Tablet as it may be excreted in breast milk. You are recommended to avoid alcohol consumption whilst on treatment with Denon Tablet. Denon Tablet is not recommended for children below 2 years of age. For children above 2 years, it is recommended to use only if the doctor has determined that the benefits outweigh the risks.

Uses of Denon Tablet

Treatment of Systemic fungal infections

Medicinal Benefits

Denon Tablet is an antifungal used to treat severe fungal infections. It is used only when other effective antifungal therapies are not available or tolerated and if potential benefits outweigh potential risks. It destroys fungal cell membranes that are essential for their survival as they prevent the entry of unwanted substances into the cells and stop the leakage of cell contents. Thus, kills fungi and treats the fungal infection.

Side Effects of Denon Tablet

  • Headache
  • Nausea
  • Stomach pain
  • Diarrhoea 

Directions for Use

Take Denon Tablet with food to avoid stomach upset or take it as advised by the doctor. Swallow the whole tablet/capsule with a glass of water. Do not break, crush or chew it.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

If you are allergic to Ketoconazole or any other medicines, please tell your doctor. If you are pregnant or planning for pregnancy, inform your doctor before taking Denon Tablet. Avoid breastfeeding while taking Denon Tablet as it may be excreted in breast milk. You are recommended to avoid alcohol consumption with Denon Tablet. If you have a loss of appetite, tiredness, stomach pain, vomiting, yellowing of skin or eyes, dark urine, or light-coloured stools, inform your doctor immediately as they might be symptoms of hepatotoxicity (liver damage). 

Therapeutic Class

ANTIFUNGALS - ORAL

Drug-Drug Interactions

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KetoconazoleIrinotecan
Critical
KetoconazoleMethylergometrine
Critical

Drug-Food Interactions

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KETOCONAZOLE-200MGGrapefruit and Grapefruit Juice
Moderate

Diet & Lifestyle Advise

  • Avoid high-risk areas such as renovated buildings, construction sites, pigeon or chick coops, and caves.
  • Wear a respiratory mask when there is a risk of exposure to spores.
  • People with a weak immune system are advised to avoid activities that involve close contact with dust or dirt including digging, yard work, and gardening.
  • Close windows and stay inside during dust storms.
  • Clean skin injuries well with soap and water to reduce the risk of developing a skin infection.

Habit Forming

No

What if I have taken an overdose of Denon Tablet

Never take more than the prescribed dose. When Denon Tablet is used at high doses, it may, though unlikely, result in decreased testosterone levels, sperm production, and an issue with the adrenal glands (adrenal insufficiency). Seek emergency medical help if an overdose is suspected.
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Alcohol

Unsafe

Avoid consumption of alcohol while taking Denon Tablet as it may increase the risk of liver damage and cause adverse effects.

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Pregnancy

Caution

Denon Tablet is a Category C pregnancy drug and is given to pregnant women only if the doctor thinks the benefits outweigh the risks.

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Breast Feeding

Unsafe

Denon Tablet may be excreted in breast milk. Therefore, it is recommended to avoid breastfeeding while taking Denon Tablet.

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Driving

Caution

Denon Tablet may cause dizziness or drowsiness. Therefore, drive only if you alert after taking Denon Tablet.

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Liver

Unsafe

Denon Tablet is contraindicated in patients with chronic or acute liver disease. Therefore, inform your doctor if you have any Liver diseases/conditions.

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Kidney

Caution

If you have any concerns regarding the use of Denon Tablet in patients with kiver diseases/conditions, consult a doctor.

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Children

Caution

Denon Tablet is not recommended for children below 2 years of age. For children above 2 years, it is recommended to use only if the doctor has determined that benefits outweigh risks.

Country of origin

India
Other Info - DE93885

Author Details

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FAQs

Denon Tablet belongs to a class of drugs called antifungals indicated to treat various systemic fungal infections such as blastomycosis (infection caused by Blastomyces fungus), chromomycosis (chronic infection of the skin and subcutaneous tissue), Coccidioidomycosis (infection caused by Coccidioides fungus), paracoccidioidomycosis (infection caused by Paracoccidioides fungus) and histoplasmosis (lung infection caused by Histoplasma fungus).
Denon Tablet works by destroying fungal cell membranes that are essential for their survival as they prevent the entry of unwanted substances into the cells and stop the leakage of cell contents. Thus, kills fungi and treats the fungal infection.
Denon Tablet is not recommended to treat fungal meningitis (fungal infection spreads to the brain and spinal cord) as it poorly penetrates into the cerebrospinal fluid. Therefore, inform your doctor if you have fungal meningitis so that appropriate medication may be prescribed.
You are recommended to avoid foods containing chocolate and caffeine such as cocoa beans, tea, coffee, cola and energy drinks while taking Denon Tablet as it may increase the adverse effects of caffeine such as drowsiness, nervousness or nausea.
You are not recommended to take Denon Tablet with simvastatin (lipid-lowering drug) as co-administration of these medicines may cause muscle problems. Therefore, please consult a doctor before taking Denon Tablet with other medicines.
No, you are not recommended to stop taking Denon Tablet without consulting your doctor as it may cause recurring infection. Therefore, take Denon Tablet for as long as your doctor has prescribed it and if you experience any difficulty while taking Denon Tablet, please consult your doctor.

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