Cuzral 200mg Tablet belongs to a class of drugs called antifungals indicated to treat various systemic fungal infections such as blastomycosis (infection caused by Blastomyces fungus), chromomycosis (chronic infection of the skin and subcutaneous tissue), Coccidioidomycosis (infection caused by Coccidioides fungus), paracoccidioidomycosis (infection caused by Paracoccidioides fungus) and histoplasmosis (lung infection caused by Histoplasma fungus). It is used only when other effective antifungal therapies are not available or tolerated and if potential benefits outweigh potential risks.

Cuzral 200mg Tablet contains Ketoconazole which works by destroying fungal cell membranes that are essential for their survival as they prevent the entry of unwanted substances into the cells and stop the leakage of cell contents. Thus, kills fungi and treats the fungal infection.

Take Cuzral 200mg Tablet as prescribed. Your doctor will advise you on how often you need to take Cuzral 200mg Tablet based on your medical condition. Some people may experience headache, nausea, stomach pain, and diarrhoea. Most of these side effects of Cuzral 200mg Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor. 

If you are allergic to Ketoconazole or any other medicines, please tell your doctor. If you are pregnant or planning for pregnancy, inform your doctor before taking Cuzral 200mg Tablet. Avoid breastfeeding while taking Cuzral 200mg Tablet as it may be excreted in breast milk. You are recommended to avoid alcohol consumption whilst on treatment with Cuzral 200mg Tablet. Cuzral 200mg Tablet is not recommended for children below 2 years of age. For children above 2 years, it is recommended to use only if the doctor has determined that the benefits outweigh the risks.

Cuzral 200mg Tablet is an antifungal used to treat severe fungal infections. It is used only when other effective antifungal therapies are not available or tolerated and if potential benefits outweigh potential risks. It destroys fungal cell membranes that are essential for their survival as they prevent the entry of unwanted substances into the cells and stop the leakage of cell contents. Thus, kills fungi and treats the fungal infection.

• Headache
• Nausea
• Stomach pain
• Diarrhoea 

If you are allergic to Ketoconazole or any other medicines, please tell your doctor. If you are pregnant or planning for pregnancy, inform your doctor before taking Cuzral 200mg Tablet. Avoid breastfeeding while taking Cuzral 200mg Tablet as it may be excreted in breast milk. You are recommended to avoid alcohol consumption with Cuzral 200mg Tablet. If you have a loss of appetite, tiredness, stomach pain, vomiting, yellowing of skin or eyes, dark urine, or light-coloured stools, inform your doctor immediately as they might be symptoms of hepatotoxicity (liver damage). 

Drug-Drug Interaction: Cuzral 200mg Tablet may interact with antiarrhythmic agents (quinidine, dofetilide), antipsychotic drugs (pimozide), drugs used to treat heartburn and acidity (omeprazole, cisapride), cholesterol-lowering medicines (simvastatin, lovastatin), medicines used to treat migraine (dihydroergotamine, ergotamine), high blood pressure lowering drugs (nisoldipine, eplerenone) and benzodiazepines (alprazolam, triazolam, midazolam).

Drug-Food Interaction: Cuzral 200mg Tablet may interact with caffeine. Therefore, avoid foods containing chocolate and caffeine such as cocoa beans, tea, coffee, cola, and energy drinks as it may increase the adverse effects of caffeine. Do not take marijuana with Cuzral 200mg Tablet as it may worsen the adverse effects of marijuana. Also, avoid consumption of alcohol with Cuzral 200mg Tablet as it may increase the risk of liver damage and cause adverse effects. 

Drug-Disease Interaction: If you have adrenal insufficiency, heart or liver problems, inform your doctor before taking Cuzral 200mg Tablet.

• QUINIDINE
• DOFETILIDE
• PIMOZIDE
• OMEPRAZOLE
• CISAPRIDE
• SIMVASTATIN
• LOVASTATIN
• DIHYDROERGOTAMINE
• ERGOTAMINE
• NISOLDIPINE
• EPLERENONE
• ALPRAZOLAM
• TRIAZOLAM
• MIDAZOLAM

• Avoid high-risk areas such as renovated buildings, construction sites, pigeon or chick coops, and caves.
• Wear a respiratory mask when there is a risk of exposure to spores.
• People with a weak immune system are advised to avoid activities that involve close contact with dust or dirt including digging, yard work, and gardening.
• Close windows and stay inside during dust storms.
• Clean skin injuries well with soap and water to reduce the risk of developing a skin infection.

Systemic fungal infections are fungal infections that affect internal organs. The fungus lives in the environment, particularly in moist soil and in decomposing organic matter such as leaves and wood. Fungi enter the body via the paranasal sinuses, gut, lungs, or skin, and may spread to other organs. If these infections are not treated with appropriate therapy or if treatment is delayed, it may lead to medical emergencies. The symptoms of systemic fungal infection in people with normal immune function include cough, fever, or loss of appetite. It can also affect people who are immune compromised.