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Written By Veda Maddala , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy
Phytoral Tablet is an antifungal medicine used in the treatment of fungal infections such as blastomycosis, coccidioidomycosis, paracoccidioidomycosis, and histoplasmosis (lung infection caused by Histoplasma fungus). This medicine works by inhibiting the growth and multiplication of fungal cells that are responsible for the growth of infection-causing fungi.
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Prescription drug

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Composition :

KETOCONAZOLE-200MG

Manufacturer/Marketer :

Micro Labs Ltd

Consume Type :

ORAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

Phytoral Tablet belongs to a class of drugs called antifungals indicated to treat various systemic fungal infections such as blastomycosis (infection caused by Blastomyces fungus), chromomycosis (chronic infection of the skin and subcutaneous tissue), Coccidioidomycosis (infection caused by Coccidioides fungus), paracoccidioidomycosis (infection caused by Paracoccidioides fungus) and histoplasmosis (lung infection caused by Histoplasma fungus). It is used only when other effective antifungal therapies are not available or tolerated and if potential benefits outweigh potential risks.

Phytoral Tablet contains Ketoconazole which works by destroying fungal cell membranes that are essential for their survival as they prevent the entry of unwanted substances into the cells and stop the leakage of cell contents. Thus, kills fungi and treats the fungal infection.

Take Phytoral Tablet as prescribed. Your doctor will advise you on how often you need to take Phytoral Tablet based on your medical condition. Some people may experience headache, nausea, stomach pain, and diarrhoea. Most of these side effects of Phytoral Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor. 

If you are allergic to Ketoconazole or any other medicines, please tell your doctor. If you are pregnant or planning for pregnancy, inform your doctor before taking Phytoral Tablet . Avoid breastfeeding while taking Phytoral Tablet as it may be excreted in breast milk. You are recommended to avoid alcohol consumption whilst on treatment with Phytoral Tablet . Phytoral Tablet is not recommended for children below 2 years of age. For children above 2 years, it is recommended to use only if the doctor has determined that the benefits outweigh the risks.

Treatment of Systemic fungal infections
Take Phytoral Tablet with food to avoid stomach upset or take it as advised by the doctor. Swallow the whole tablet/capsule with a glass of water. Do not break, crush or chew it.

Phytoral Tablet is an antifungal used to treat severe fungal infections. It is used only when other effective antifungal therapies are not available or tolerated and if potential benefits outweigh potential risks. It destroys fungal cell membranes that are essential for their survival as they prevent the entry of unwanted substances into the cells and stop the leakage of cell contents. Thus, kills fungi and treats the fungal infection.

Phytoral Tablet contains Ketoconazole which works by destroying fungal cell membranes that are essential for their survival as they prevent the entry of unwanted substances into the cells and stop the leakage of cell contents. Thus, kills fungi and treats the fungal infection.
Store in a cool and dry place away from sunlight

  • Headache
  • Nausea
  • Stomach pain
  • Diarrhoea 
Never take more than the prescribed dose. When Phytoral Tablet is used at high doses, it may, though unlikely, result in decreased testosterone levels, sperm production, and an issue with the adrenal glands (adrenal insufficiency). Seek emergency medical help if an overdose is suspected.

If you are allergic to Ketoconazole or any other medicines, please tell your doctor. If you are pregnant or planning for pregnancy, inform your doctor before taking Phytoral Tablet . Avoid breastfeeding while taking Phytoral Tablet as it may be excreted in breast milk. You are recommended to avoid alcohol consumption with Phytoral Tablet . If you have a loss of appetite, tiredness, stomach pain, vomiting, yellowing of skin or eyes, dark urine, or light-coloured stools, inform your doctor immediately as they might be symptoms of hepatotoxicity (liver damage). 

verifiedApollotooltip
KetoconazoleTriazolam
Critical
KetoconazoleMidazolam
Critical

Drug-Drug Interactions

KetoconazoleTriazolam
Critical
How does the drug interact with Phytoral Tablet 10's:
When Triazolam is taken with Phytoral Tablet 10's, it can increase the risk of drowsiness and slowed breathing.

How to manage the interaction:
Taking Triazolam with Phytoral Tablet 10's is not recommended as it can cause an interaction, it can be taken if prescribed by the doctor. Do not stop using any medications without talking to a doctor.
KetoconazoleMidazolam
Critical
How does the drug interact with Phytoral Tablet 10's:
Co-administration of Phytoral Tablet 10's and Midazolam may increase the risk of side effects.

How to manage the interaction:
Although taking Phytoral Tablet 10's and Midazolam together is not recommended as it may result in an interaction, they can be taken if prescribed by a doctor. Consult a doctor if you have excessive or prolonged sleepiness and breathing issues. Do not discontinue any medication without consulting a doctor.
KetoconazoleNisoldipine
Critical
How does the drug interact with Phytoral Tablet 10's:
When Nisoldipine is taken with Phytoral Tablet 10's, it can increase the blood levels of Nimodipine which may lead to serious side effects (irregular heart rhythm, fluid retention, swelling, and extremely low blood pressure).

How to manage the interaction:
Taking Phytoral Tablet 10's with Nisoldipine can cause an interaction, but it can be taken if prescribed by the doctor. However, if you experience irregular heart rhythm, fluid retention, swelling, and extremely low blood pressure while using these medications, consult the doctor. Do not stop using any medications without talking to a doctor.
KetoconazoleMethylergometrine
Critical
How does the drug interact with Phytoral Tablet 10's:
Using Phytoral Tablet 10's with Methylergometrine can increase the concentration of Methylergometrine, which may lead to side effects.

How to manage the interaction:
Taking Phytoral Tablet 10's with Methylergometrine is not recommended as it can cause an interaction, but it can be taken if prescribed by the doctor. Do not discontinue any medication without consulting a doctor.
KetoconazoleTicagrelor
Critical
How does the drug interact with Phytoral Tablet 10's:
Co-administration of ticagrelor with Phytoral Tablet 10's can cause severe bleeding.

How to manage the interaction:
Taking Ticagrelor with Phytoral Tablet 10's is not recommended as it can cause an interaction, it can be taken if prescribed by the doctor. However, if you experience any unusual bleeding or bruising, swelling, vomiting, blood in your urine or stools, headache, dizziness, or weakness, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
KetoconazoleLomitapide
Critical
How does the drug interact with Phytoral Tablet 10's:
When Lomitapide is taken with Phytoral Tablet 10's, it may increase the risk of side effects.

How to manage the interaction:
Taking Phytoral Tablet 10's with Lomitapide is not recommended as it can cause an interaction, but it can be taken if prescribed by the doctor. However, if you experience symptoms such as fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, vomiting, dark urine, light stools, and skin or eye yellowing, decreased hunger, consult the doctor immediately. Do not stop using any medications without talking to the doctor.
KetoconazoleMethadone
Critical
How does the drug interact with Phytoral Tablet 10's:
When Methadone is taken with Phytoral Tablet 10's, it can increase the risk of serious side effects such as respiratory problems, low blood pressure, irregular heart rhythm.

How to manage the interaction:
Taking Phytoral Tablet 10's with Methadone is not recommended as it can cause an interaction, it can be taken if prescribed by the doctor. However, if you experience breathing difficulty, fainting, heart palpitations, consult the doctor immediately. Do not discontinue any medication without consulting a doctor.
KetoconazoleCisapride
Critical
How does the drug interact with Phytoral Tablet 10's:
When Cisapride is taken with Phytoral Tablet 10's, it can increase the chance of a serious abnormal heart rhythm.

How to manage the interaction:
Taking Cisapride with Phytoral Tablet 10's is not recommended as it can cause an interaction, it can be taken if prescribed by the doctor. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not stop any medications without a doctor's advice.
KetoconazoleIrinotecan
Critical
How does the drug interact with Phytoral Tablet 10's:
Using irinotecan together with Phytoral Tablet 10's can increase the risk of side effects.

How to manage the interaction:
Taking Phytoral Tablet 10's with Irinotecan is not recommended as it can cause an interaction, but it can be taken if prescribed by the doctor. However, if you experience any symptoms such as paleness, fatigue, dizziness, fainting, unexpected bruising or bleeding, fever, chills, diarrhea, sore throat, muscle aches, breathing difficulty, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination, consult the doctor immediately.
KetoconazoleColchicine
Critical
How does the drug interact with Phytoral Tablet 10's:
Using colchicine together with Phytoral Tablet 10's may increase the blood levels of colchicine, increasing the risk of serious side effects.

How to manage the interaction:
Although taking Phytoral Tablet 10's with Colchicine is not recommended as it can cause an interaction, they can be taken if prescribed by a doctor. However, contact a doctor if you experience abdominal pain, nausea, vomiting, diarrhea, fever, muscle pain, weakness, fatigue, and/or numbness or tingling in your hands and feet. Do not stop using any medications without consulting a doctor
verifiedApollotooltip
KETOCONAZOLE-200MGGrapefruit and Grapefruit Juice
Moderate

Drug-Food Interactions

KETOCONAZOLE-200MGGrapefruit and Grapefruit Juice
Moderate
Common Foods to Avoid:
Grapefruit Juice, Grapefruit

How to manage the interaction:
Consumption of grapefruit or its juice with Phytoral Tablet 10's may result in side effects such as joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of hunger, dark urine, light colored stools, and yellowing of the skin or eyes. Avoid consuming grapefruit, grapefruit juice, or any supplements that include grapefruit extract while taking Phytoral Tablet 10's.
  • Avoid high-risk areas such as renovated buildings, construction sites, pigeon or chick coops, and caves.
  • Wear a respiratory mask when there is a risk of exposure to spores.
  • People with a weak immune system are advised to avoid activities that involve close contact with dust or dirt including digging, yard work, and gardening.
  • Close windows and stay inside during dust storms.
  • Clean skin injuries well with soap and water to reduce the risk of developing a skin infection.
No
ANTIFUNGALS - ORAL

Phytoral Tablet Substitute

Substitutes safety advice
  • Fungicide Tablet 10's

    47.52per tablet
  • Kenz Tablet 10's

    by AYUR

    21.60per tablet
  • Hyphoral Tablet 10's

    38.03per tablet
  • Ketocip 200 mg Tablet 10's

    21.78per tablet
  • Ketafung Tablet 10's

    20.70per tablet
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Unsafe

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Caution

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Unsafe

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Caution

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Unsafe

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Caution

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Caution

FAQs

Phytoral Tablet belongs to a class of drugs called antifungals indicated to treat various systemic fungal infections such as blastomycosis (infection caused by Blastomyces fungus), chromomycosis (chronic infection of the skin and subcutaneous tissue), Coccidioidomycosis (infection caused by Coccidioides fungus), paracoccidioidomycosis (infection caused by Paracoccidioides fungus) and histoplasmosis (lung infection caused by Histoplasma fungus).
Phytoral Tablet works by destroying fungal cell membranes that are essential for their survival as they prevent the entry of unwanted substances into the cells and stop the leakage of cell contents. Thus, kills fungi and treats the fungal infection.
Phytoral Tablet is not recommended to treat fungal meningitis (fungal infection spreads to the brain and spinal cord) as it poorly penetrates into the cerebrospinal fluid. Therefore, inform your doctor if you have fungal meningitis so that appropriate medication may be prescribed.
You are recommended to avoid foods containing chocolate and caffeine such as cocoa beans, tea, coffee, cola and energy drinks while taking Phytoral Tablet as it may increase the adverse effects of caffeine such as drowsiness, nervousness or nausea.
You are not recommended to take Phytoral Tablet with simvastatin (lipid-lowering drug) as co-administration of these medicines may cause muscle problems. Therefore, please consult a doctor before taking Phytoral Tablet with other medicines.
No, you are not recommended to stop taking Phytoral Tablet without consulting your doctor as it may cause recurring infection. Therefore, take Phytoral Tablet for as long as your doctor has prescribed it and if you experience any difficulty while taking Phytoral Tablet , please consult your doctor.
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Other Info - PHY0002

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