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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Granifer Injection 3 ml is used to treat nausea and vomiting caused by medical treatments after surgery, chemotherapy, or radiation treatment for cancer. It contains Granisetron, which works by blocking the brain's serotonin (chemical messenger) activity that triggers nausea and vomiting during cancer treatment (chemotherapy or radiation therapy) or after surgery. Common side effects of Granifer Injection 3 ml include diarrhoea, constipation, stomach pain, weakness, headache, fever, drowsiness, trouble sleeping, pain, redness, and swelling at the injection site.
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Whats That

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Composition :

GRANISETRON-1MG

Manufacturer/Marketer :

Pharmafer Pvt Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

About Granifer Injection 3 ml

Granifer Injection 3 ml belongs to the class of 'anti-emetic' drugs, primarily used to treat nausea and vomiting caused by medical treatments after surgery or chemotherapy or radiation treatment for cancer. Nausea is defined as stomach discomfort and the sensation of an urge to vomit. Vomiting is the forcible voluntary or involuntary emptying of contents of the stomach through the mouth.

Granifer Injection 3 ml contains an anti-emetic (eases vomiting symptoms) medicine, 'Granisetron', that belongs to the class of 5-HT3 receptor antagonists (also called serotonin receptor antagonists or serotonin blockers). It works by blocking the brain's serotonin (chemical messenger) activity that triggers nausea and vomiting during cancer treatment (chemotherapy or radiation therapy) or after surgery.

Granifer Injection 3 ml will be administered by a healthcare professional; do not self-administer. Your doctor will decide the dose and duration based on the severity of your medical condition. Common side effects of Granifer Injection 3 ml include diarrhoea, constipation, stomach pain, weakness, headache, fever, drowsiness, trouble sleeping, pain, redness, and swelling at the injection site. These side effects are not familiar to everyone and vary individually. If you notice any side effects that are not manageable, please consult your doctor.

If you use other prescription or non-prescription medicines, inform your doctor before using Granifer Injection 3 ml. Let your doctor know if you have any liver, kidney or heart diseases, stomach/intestinal problems, allergic reactions, and low levels of potassium and magnesium in the blood before starting Granifer Injection 3 ml. This medicine may make you dizzy or drowsy; hence avoid driving or operating machinery if you are not mentally alert. Consult your doctor before using Granifer Injection 3 ml if you are pregnant, planning for pregnancy or breastfeeding. Avoid consuming alcohol while being treated with Granifer Injection 3 ml as it could lead to unwanted side effects. 

Uses of Granifer Injection 3 ml

Treatment of Nausea and vomiting

Directions for Use

It will be administered by a healthcare professional; do not self-administer.

Medicinal Benefits

Granifer Injection 3 ml contains an anti-emetic medicine, 'Granisetron', that treats nausea and vomiting caused due to cancer treatment (chemotherapy or radiation therapy) or after surgery. Granisetron belongs to the class of 5-HT3 receptor antagonists (also called serotonin receptor antagonists or serotonin blockers). When the cells lining the gastrointestinal tract are damaged by chemotherapy or radiation therapy, they release a natural substance called serotonin (5HT3, 5-hydroxytryptamine). This serotonin binds to serotonin receptors on nerves that induces nausea and vomiting. Granifer Injection 3 ml works by blocking the brain's serotonin activity and preventing postoperative nausea and vomiting. 

How Granifer Injection 3 ml Works

Granifer Injection 3 ml contains an anti-emetic (eases vomiting symptoms) medicine, 'Granisetron', that belongs to the class of 5-HT3 receptor antagonists (also called serotonin receptor antagonists or serotonin blockers). It works by blocking the brain's serotonin (chemical messenger) activity that triggers nausea and vomiting during cancer treatment (chemotherapy or radiation therapy) or after surgery.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Granifer Injection 3 ml

  • Diarrhoea
  • Constipation
  • Stomach pain
  • Weakness
  • Headache
  • Fever
  • Dizziness
  • Drowsiness
  • Trouble sleeping
  • Pain, redness, and swelling at the injection site

What if I have taken an overdose of Granifer Injection 3 ml

Since Granifer Injection 3 ml is given in a controlled medical setting by a healthcare professional, an overdose is not likely to occur. If you think there has been an overdose or experiencing any adverse events, get medical care right away. In a medical setting, an overdose would be treated quickly. Overdose of Granifer Injection 3 ml may cause headache.

Drug Warnings

Seeking medical advice if you use prescription or non-prescription medicines while being treated with Granifer Injection 3 ml is suggested. Inform your doctor about a history of stomach/intestinal problems, heart diseases, electrolyte imbalance (potassium, sodium or calcium), and liver or kidney diseases before starting Granifer Injection 3 ml. Please consult your doctor if you are pregnant or breastfeeding if the doctor advised you Granifer Injection 3 ml. This medicine may make you feel dizzy, so drive or operate machinery only if you are alert. Avoid consuming alcohol during the course, as it could lead to increased dizziness. Granifer Injection 3 ml is not recommended in children below two years of age.

Drug-Drug Interactions

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GranisetronSparfloxacin
Critical
GranisetronMesoridazine
Critical

Drug-Drug Interactions

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GranisetronSparfloxacin
Critical
How does the drug interact with Granifer Inj 3ml:
Taking Granifer Inj 3ml with Sparfloxacin can increase the chance of a serious abnormal heart rhythm.

How to manage the interaction:
Taking Granifer Inj 3ml with Sparfloxacin is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not stop using any medications without talking to a doctor.
GranisetronMesoridazine
Critical
How does the drug interact with Granifer Inj 3ml:
Taking Granifer Inj 3ml with mesoridazine can increase the risk of an irregular heart rhythm. I

How to manage the interaction:
Taking Mesoridazine with Granifer Inj 3ml is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, if you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations while taking any of these drugs, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
GranisetronCisapride
Critical
How does the drug interact with Granifer Inj 3ml:
Taking Granifer Inj 3ml with Cisapride can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Granifer Inj 3ml with Cisapride is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, if you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations while taking any of these drugs, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
GranisetronDronedarone
Critical
How does the drug interact with Granifer Inj 3ml:
Taking Granifer Inj 3ml with Dronedarone can increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking Granifer Inj 3ml with Dronedarone is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, if you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations while taking any of these drugs, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
GranisetronThioridazine
Critical
How does the drug interact with Granifer Inj 3ml:
Taking Granifer Inj 3ml with Thioridazine can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Granifer Inj 3ml with Thioridazine is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, if you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations while taking any of these drugs, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
GranisetronPimozide
Critical
How does the drug interact with Granifer Inj 3ml:
Taking Granifer Inj 3ml with Pimozide can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Granifer Inj 3ml with Pimozide is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, if you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations while taking any of these drugs, consult a doctor immediately. Do not stop using any medications without talking to a doctor.
GranisetronSaquinavir
Critical
How does the drug interact with Granifer Inj 3ml:
When Granifer Inj 3ml is taken with Saquinavir, can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Granifer Inj 3ml with Saquinavir is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, if you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations while taking any of these drugs, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
GranisetronZiprasidone
Critical
How does the drug interact with Granifer Inj 3ml:
Taking Granifer Inj 3ml with Ziprasidone can increase the risk of abnormal heart rhythm.

How to manage the interaction:
Taking Granifer Inj 3ml with Ziprasidone is not recommended, as it can result in an interaction, it can be taken if a doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not stop using any medications without talking to a doctor.
GranisetronHaloperidol
Severe
How does the drug interact with Granifer Inj 3ml:
Co-administration of Granifer Inj 3ml with Haloperidol increases the risk of irregular heart rhythm. The risk increases in patients with a history of heart illnesses or electrolyte imbalances.

How to manage the interaction:
Co-administration of Granifer Inj 3ml and Haloperidol can lead to an interaction, it can be taken if advised by a doctor. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
GranisetronDoxepin
Severe
How does the drug interact with Granifer Inj 3ml:
The use of Granifer Inj 3ml and doxepin can increase the risk of serotonin syndrome (A condition in which a chemical called serotonin builds up in body) and increase the risk of irregular heart rhythms.

How to manage the interaction:
Co-administration of Granifer Inj 3ml and Doxepin can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like confusion, hallucination, seizure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremors, incoordination, stomach cramps, nausea, vomiting, diarrhea, sudden dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, consult the doctor immediately. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Avoid chocolates, junk food, cheese, processed food, alcohol, and smoking. 
  • You can try increasing your mindfulness by doing yoga, meditation, mindfulness-based cognitive therapy, and stress reduction techniques.
  • Drink enough water to stay hydrated and limit or avoid alcohol and caffeine.
  • Include a diet rich in whole grains, vegetables, and fruits.
  • You can include antioxidants in your daily diet, like ashwagandha, omega-3 fatty acids, green tea, and lemon.
  • Try to spend time with your friends and family. Having a strong social network may help you lower your risk of anxiety.

Habit Forming

No

Therapeutic Class

ANTIEMETICS

Granifer Injection 3 ml Substitute

Substitutes safety advice
  • Grandem MD Tablet 10's

    by AYUR

    10.35per tablet
  • Graniforce -MD Tablet 10's

    by Others

    9.23per tablet
  • Grandem-1 Tablet 10's

    by AYUR

    9.45per tablet
  • Grandem Syrup 10 ml

    by Others

    5.31per tablet
  • Graniforce Syrup 10 ml

    by Others

    5.31per tablet
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Alcohol

Caution

You are recommended to limit or avoid alcohol consumption while taking Granifer Injection 3 ml. Alcohol intake, along with Granifer Injection 3 ml, may lead to unwanted side effects and cause increased dizziness.

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Pregnancy

Caution

It is not known if Granifer Injection 3 ml affects pregnancy. Please inform your doctor if you are pregnant or planning pregnancy before receiving Granifer Injection 3 ml.

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Breast Feeding

Caution

It is not known if this medicine passes into breast milk. Please inform your doctor before taking Granifer Injection 3 ml if you are a nursing mother.

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Driving

Caution

Granifer Injection 3 ml may make you feel dizzy, affecting your mental ability. Do not drive or operate machinery if you experience dizziness.

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Liver

Caution

Granifer Injection 3 ml should be used with caution if you have liver disease. Please inform your doctor if you have a history of liver impairment before starting Granifer Injection 3 ml.

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Kidney

Caution

Granifer Injection 3 ml should be used with caution if you have kidney problems. Please inform your doctor if you have a history of kidney impairment/kidney disease.

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Children

Caution

Safety and efficacy of Granifer Injection 3 ml have not been established in children below 2 years of age.

FAQs

Granifer Injection 3 ml is used to treat Nausea and vomiting.

Granifer Injection 3 ml contains Granisetron, an anti-emetic drug. It is a serotonin blocker that blocks the activity of serotonin, a chemical messenger that induces nausea and vomiting after treatments like chemotherapy and radiation therapy. Thus, Granifer Injection 3 ml relieves post-operative nausea and vomiting symptoms.

Granifer Injection 3 ml may cause constipation as one of its side effects. You can avoid it by including high-fibre food in your diet that improves your digestion. Limit the intake of alcohol to manage your constipation.

Granifer Injection 3 ml should be used with caution if you have recent stomach/intestinal problems like stomach ache, wind, feeling or being sick, difficulty passing stools, heart rhythm disorder, a recent stomach or intestinal surgery, electrolyte imbalance (potassium, sodium or calcium), and liver or kidney diseases.

You are advised to complete the course prescribed by your doctor. Please do not stop taking this medicine unless advised by your doctor since it may lead to recurrent episodes of nausea and vomiting.

Common side effects of Granifer Injection 3 ml include diarrhoea, constipation, stomach pain, weakness, headache, fever, drowsiness, trouble sleeping, pain, redness, and swelling at the injection site. These side effects are not familiar to everyone and vary individually. If you notice any side effects that are not manageable, please consult your doctor.

It is not known if Granifer Injection 3 ml affects pregnancy. Please inform your doctor if you are pregnant or planning pregnancy before receiving Granifer Injection 3 ml. The doctor will prescribe Granifer Injection 3 ml only if clearly needed.

Few studies suggest that Granifer Injection 3 ml is more effective than ondansetron. However, the doctor will decide which medicine is suitable and better for you based on your condition.

Country of origin

India

Manufacturer/Marketer address

Office No: 9, Building No: C-2, 3rd Floor. Brahma Estate, Kondhwa Khurd, Pune - 411 048, Maharashtra.
Other Info - GRA0440

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