apollo
0
Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Dec 7, 2024 | 2:20 PM IST
Granibrit Injection 1 ml is used to treat nausea and vomiting caused by medical treatments after surgery, chemotherapy, or radiation treatment for cancer. It contains Granisetron, which works by blocking the brain's serotonin (chemical messenger) activity that triggers nausea and vomiting during cancer treatment (chemotherapy or radiation therapy) or after surgery. Common side effects of Granibrit Injection 1 ml include diarrhoea, constipation, stomach pain, weakness, headache, fever, drowsiness, trouble sleeping, pain, redness, and swelling at the injection site.
Read more
Prescription drug

Whats That

tooltip
Prescription drug
 Trailing icon
Consult Doctor

Composition

GRANISETRON-1MG

Manufacturer/Marketer

Biocrit Healthcare Pvt Ltd

Consume Type

PARENTERAL

Return Policy

Not Returnable

for this medicine

About Granibrit Injection 1 ml

Granibrit Injection 1 ml belongs to the class of 'anti-emetic' drugs, primarily used to treat nausea and vomiting caused by medical treatments after surgery or chemotherapy or radiation treatment for cancer. Nausea is defined as stomach discomfort and the sensation of an urge to vomit. Vomiting is the forcible voluntary or involuntary emptying of contents of the stomach through the mouth.

Granibrit Injection 1 ml contains an anti-emetic (eases vomiting symptoms) medicine, 'Granisetron', that belongs to the class of 5-HT3 receptor antagonists (also called serotonin receptor antagonists or serotonin blockers). It works by blocking the brain's serotonin (chemical messenger) activity that triggers nausea and vomiting during cancer treatment (chemotherapy or radiation therapy) or after surgery.

Granibrit Injection 1 ml will be administered by a healthcare professional; do not self-administer. Your doctor will decide the dose and duration based on the severity of your medical condition. Common side effects of Granibrit Injection 1 ml include diarrhoea, constipation, stomach pain, weakness, headache, fever, drowsiness, trouble sleeping, pain, redness, and swelling at the injection site. These side effects are not familiar to everyone and vary individually. If you notice any side effects that are not manageable, please consult your doctor.

If you use other prescription or non-prescription medicines, inform your doctor before using Granibrit Injection 1 ml. Let your doctor know if you have any liver, kidney or heart diseases, stomach/intestinal problems, allergic reactions, and low levels of potassium and magnesium in the blood before starting Granibrit Injection 1 ml. This medicine may make you dizzy or drowsy; hence avoid driving or operating machinery if you are not mentally alert. Consult your doctor before using Granibrit Injection 1 ml if you are pregnant, planning for pregnancy or breastfeeding. Avoid consuming alcohol while being treated with Granibrit Injection 1 ml as it could lead to unwanted side effects. 

Uses of Granibrit Injection 1 ml

Treatment of Nausea and vomiting

Medicinal Benefits

Granibrit Injection 1 ml contains an anti-emetic medicine, 'Granisetron', that treats nausea and vomiting caused due to cancer treatment (chemotherapy or radiation therapy) or after surgery. Granisetron belongs to the class of 5-HT3 receptor antagonists (also called serotonin receptor antagonists or serotonin blockers). When the cells lining the gastrointestinal tract are damaged by chemotherapy or radiation therapy, they release a natural substance called serotonin (5HT3, 5-hydroxytryptamine). This serotonin binds to serotonin receptors on nerves that induces nausea and vomiting. Granibrit Injection 1 ml works by blocking the brain's serotonin activity and preventing postoperative nausea and vomiting. 

Directions for Use

It will be administered by a healthcare professional; do not self-administer.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Granibrit Injection 1 ml

  • Diarrhoea
  • Constipation
  • Stomach pain
  • Weakness
  • Headache
  • Fever
  • Dizziness
  • Drowsiness
  • Trouble sleeping
  • Pain, redness, and swelling at the injection site

Drug Warnings

Seeking medical advice if you use prescription or non-prescription medicines while being treated with Granibrit Injection 1 ml is suggested. Inform your doctor about a history of stomach/intestinal problems, heart diseases, electrolyte imbalance (potassium, sodium or calcium), and liver or kidney diseases before starting Granibrit Injection 1 ml. Please consult your doctor if you are pregnant or breastfeeding if the doctor advised you Granibrit Injection 1 ml. This medicine may make you feel dizzy, so drive or operate machinery only if you are alert. Avoid consuming alcohol during the course, as it could lead to increased dizziness. Granibrit Injection 1 ml is not recommended in children below two years of age.

Drug Interactions

Drug-Drug Interaction: Granibrit Injection 1 ml may interact with antidepressants (fluoxetine, duloxetine), heart-related drugs (amiodarone, sotalol), antipsychotic drugs (pimozide), antibiotics (erythromycin), and St. John's wort, a plant-based medicine used for depression and mood disorders.

Drug-Food Interaction: Alcohol may increase dizziness when taken with Granibrit Injection 1 ml.

Drug-Disease Interaction: Before using Granibrit Injection 1 ml, let your doctor know if you have any stomach/intestinal problems like stomach ache, wind, feeling or being sick, difficulty passing stools, electrolyte imbalance (potassium, sodium or calcium), heart problems, liver or kidney diseases.

Drug-Drug Interactions Checker List

  • FLUOXETINE
  • DULOXETINE
  • AMIODARONE
  • SOTALOL
  • PIMOZIDE
  • ERYTHROMYCIN

Habit Forming

No

Diet & Lifestyle Advise

  • Avoid chocolates, junk food, cheese, processed food, alcohol, and smoking. 
  • You can try increasing your mindfulness by doing yoga, meditation, mindfulness-based cognitive therapy, and stress reduction techniques.
  • Drink enough water to stay hydrated and limit or avoid alcohol and caffeine.
  • Include a diet rich in whole grains, vegetables, and fruits.
  • You can include antioxidants in your daily diet, like ashwagandha, omega-3 fatty acids, green tea, and lemon.
  • Try to spend time with your friends and family. Having a strong social network may help you lower your risk of anxiety.

Special Advise

  • Let your doctor know you are taking Granibrit Injection 1 ml if you undergo medical tests.
  • Heart function monitoring with an ECG or EKG (electrocardiogram) is recommended in heart patients since Granibrit Injection 1 ml may cause irregular heartbeat and QT prolongation (heart muscle takes longer than normal to recharge between beats).

Disease/Condition Glossary

Nausea is defined as stomach discomfort and the sensation of an urge to vomit. It is a precursor to vomiting. It is not a painful symptom but can cause discomfort in the chest, upper abdomen, or back of the throat. Nausea can be triggered by various factors like motion from a car and plane, taking pills on an empty stomach, eating too much or too little, and drinking excessive amounts of alcohol. 

Vomiting or throwing up is the forcible voluntary or involuntary emptying of contents of the stomach through the mouth. Vomiting can also occur without any underlying diseases like pregnancy, hangovers, overeating, and motion sickness. Nausea or vomiting may be triggered by many factors, including food poisoning, gastritis (inflammation of the stomach lining), an ulcer, or bulimia (eating disorder).

bannner image

Alcohol

Caution

You are recommended to limit or avoid alcohol consumption while taking Granibrit Injection 1 ml. Alcohol intake, along with Granibrit Injection 1 ml, may lead to unwanted side effects and cause increased dizziness.

bannner image

Pregnancy

Caution

It is not known if Granibrit Injection 1 ml affects pregnancy. Please inform your doctor if you are pregnant or planning pregnancy before receiving Granibrit Injection 1 ml.

bannner image

Breast Feeding

Caution

It is not known if this medicine passes into breast milk. Please inform your doctor before taking Granibrit Injection 1 ml if you are a nursing mother.

bannner image

Driving

Caution

Granibrit Injection 1 ml may make you feel dizzy, affecting your mental ability. Do not drive or operate machinery if you experience dizziness.

bannner image

Liver

Caution

Granibrit Injection 1 ml should be used with caution if you have liver disease. Please inform your doctor if you have a history of liver impairment before starting Granibrit Injection 1 ml.

bannner image

Kidney

Caution

Granibrit Injection 1 ml should be used with caution if you have kidney problems. Please inform your doctor if you have a history of kidney impairment/kidney disease.

bannner image

Children

Caution

Safety and efficacy of Granibrit Injection 1 ml have not been established in children below 2 years of age.

Country of origin

India

Manufacturer/Marketer address

KONARK POORAM HOUSING SOCIETY PH III, BLDG U-2 SR NO 7 KONDHWA PUNE Pune MH 411048 IN
Other Info - GRA0436

Author Details

Doctor imageWe provide you with authentic, trustworthy and relevant information

FAQs

Granibrit Injection 1 ml is used to treat Nausea and vomiting.
Granibrit Injection 1 ml contains Granisetron, an anti-emetic drug. It is a serotonin blocker that blocks the activity of serotonin, a chemical messenger that induces nausea and vomiting after treatments like chemotherapy and radiation therapy. Thus, Granibrit Injection 1 ml relieves post-operative nausea and vomiting symptoms.
Granibrit Injection 1 ml may cause constipation as one of its side effects. You can avoid it by including high-fibre food in your diet that improves your digestion. Limit the intake of alcohol to manage your constipation.
Granibrit Injection 1 ml should be used with caution if you have recent stomach/intestinal problems like stomach ache, wind, feeling or being sick, difficulty passing stools, heart rhythm disorder, a recent stomach or intestinal surgery, electrolyte imbalance (potassium, sodium or calcium), and liver or kidney diseases.
You are advised to complete the course prescribed by your doctor. Please do not stop taking this medicine unless advised by your doctor since it may lead to recurrent episodes of nausea and vomiting.
Common side effects of Granibrit Injection 1 ml include diarrhoea, constipation, stomach pain, weakness, headache, fever, drowsiness, trouble sleeping, pain, redness, and swelling at the injection site. These side effects are not familiar to everyone and vary individually. If you notice any side effects that are not manageable, please consult your doctor.
It is not known if Granibrit Injection 1 ml affects pregnancy. Please inform your doctor if you are pregnant or planning pregnancy before receiving Granibrit Injection 1 ml. The doctor will prescribe Granibrit Injection 1 ml only if clearly needed.
Few studies suggest that Granibrit Injection 1 ml is more effective than ondansetron. However, the doctor will decide which medicine is suitable and better for you based on your condition.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.