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Composition

GRANISETRON-1MG

Consume Type

PARENTERAL

Return Policy

Not Returnable

for this medicine

About Granikal 1mg Injection

Granikal 1mg Injection belongs to the class of 'anti-emetic' drugs, primarily used to treat nausea and vomiting caused by medical treatments after surgery or chemotherapy or radiation treatment for cancer. Nausea is defined as stomach discomfort and the sensation of an urge to vomit. Vomiting is the forcible voluntary or involuntary emptying of contents of the stomach through the mouth.

Granikal 1mg Injection contains an anti-emetic (eases vomiting symptoms) medicine, 'Granisetron', that belongs to the class of 5-HT3 receptor antagonists (also called serotonin receptor antagonists or serotonin blockers). It works by blocking the brain's serotonin (chemical messenger) activity that triggers nausea and vomiting during cancer treatment (chemotherapy or radiation therapy) or after surgery.

Granikal 1mg Injection will be administered by a healthcare professional; do not self-administer. Your doctor will decide the dose and duration based on the severity of your medical condition. Common side effects of Granikal 1mg Injection include diarrhoea, constipation, stomach pain, weakness, headache, fever, drowsiness, trouble sleeping, pain, redness, and swelling at the injection site. These side effects are not familiar to everyone and vary individually. If you notice any side effects that are not manageable, please consult your doctor.

If you use other prescription or non-prescription medicines, inform your doctor before using Granikal 1mg Injection. Let your doctor know if you have any liver, kidney or heart diseases, stomach/intestinal problems, allergic reactions, and low levels of potassium and magnesium in the blood before starting Granikal 1mg Injection. This medicine may make you dizzy or drowsy; hence avoid driving or operating machinery if you are not mentally alert. Consult your doctor before using Granikal 1mg Injection if you are pregnant, planning for pregnancy or breastfeeding. Avoid consuming alcohol while being treated with Granikal 1mg Injection as it could lead to unwanted side effects. 

Uses of Granikal 1mg Injection

Treatment of Nausea and vomiting

Medicinal Benefits

Granikal 1mg Injection contains an anti-emetic medicine, 'Granisetron', that treats nausea and vomiting caused due to cancer treatment (chemotherapy or radiation therapy) or after surgery. Granisetron belongs to the class of 5-HT3 receptor antagonists (also called serotonin receptor antagonists or serotonin blockers). When the cells lining the gastrointestinal tract are damaged by chemotherapy or radiation therapy, they release a natural substance called serotonin (5HT3, 5-hydroxytryptamine). This serotonin binds to serotonin receptors on nerves that induces nausea and vomiting. Granikal 1mg Injection works by blocking the brain's serotonin activity and preventing postoperative nausea and vomiting. 

Side Effects of Granikal 1mg Injection

  • Diarrhoea
  • Constipation
  • Stomach pain
  • Weakness
  • Headache
  • Fever
  • Dizziness
  • Drowsiness
  • Trouble sleeping
  • Pain, redness, and swelling at the injection site

Directions for Use

It will be administered by a healthcare professional; do not self-administer.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Seeking medical advice if you use prescription or non-prescription medicines while being treated with Granikal 1mg Injection is suggested. Inform your doctor about a history of stomach/intestinal problems, heart diseases, electrolyte imbalance (potassium, sodium or calcium), and liver or kidney diseases before starting Granikal 1mg Injection. Please consult your doctor if you are pregnant or breastfeeding if the doctor advised you Granikal 1mg Injection. This medicine may make you feel dizzy, so drive or operate machinery only if you are alert. Avoid consuming alcohol during the course, as it could lead to increased dizziness. Granikal 1mg Injection is not recommended in children below two years of age.

Therapeutic Class

ANTIEMETICS

Drug Interactions

Drug-Drug Interaction: Granikal 1mg Injection may interact with antidepressants (fluoxetine, duloxetine), heart-related drugs (amiodarone, sotalol), antipsychotic drugs (pimozide), antibiotics (erythromycin), and St. John's wort, a plant-based medicine used for depression and mood disorders.

Drug-Food Interaction: Alcohol may increase dizziness when taken with Granikal 1mg Injection.

Drug-Disease Interaction: Before using Granikal 1mg Injection, let your doctor know if you have any stomach/intestinal problems like stomach ache, wind, feeling or being sick, difficulty passing stools, electrolyte imbalance (potassium, sodium or calcium), heart problems, liver or kidney diseases.

Drug-Drug Interactions Checker List

  • FLUOXETINE
  • DULOXETINE
  • AMIODARONE
  • SOTALOL
  • PIMOZIDE
  • ERYTHROMYCIN

Diet & Lifestyle Advise

  • Avoid chocolates, junk food, cheese, processed food, alcohol, and smoking. 
  • You can try increasing your mindfulness by doing yoga, meditation, mindfulness-based cognitive therapy, and stress reduction techniques.
  • Drink enough water to stay hydrated and limit or avoid alcohol and caffeine.
  • Include a diet rich in whole grains, vegetables, and fruits.
  • You can include antioxidants in your daily diet, like ashwagandha, omega-3 fatty acids, green tea, and lemon.
  • Try to spend time with your friends and family. Having a strong social network may help you lower your risk of anxiety.

Habit Forming

No

What if I have taken an overdose of Granikal 1mg Injection

Since Granikal 1mg Injection is given in a controlled medical setting by a healthcare professional, an overdose is not likely to occur. If you think there has been an overdose or experiencing any adverse events, get medical care right away. In a medical setting, an overdose would be treated quickly. Overdose of Granikal 1mg Injection may cause headache.

Special Advise

  • Let your doctor know you are taking Granikal 1mg Injection if you undergo medical tests.
  • Heart function monitoring with an ECG or EKG (electrocardiogram) is recommended in heart patients since Granikal 1mg Injection may cause irregular heartbeat and QT prolongation (heart muscle takes longer than normal to recharge between beats).

Disease/Condition Glossary

Nausea is defined as stomach discomfort and the sensation of an urge to vomit. It is a precursor to vomiting. It is not a painful symptom but can cause discomfort in the chest, upper abdomen, or back of the throat. Nausea can be triggered by various factors like motion from a car and plane, taking pills on an empty stomach, eating too much or too little, and drinking excessive amounts of alcohol. 

Vomiting or throwing up is the forcible voluntary or involuntary emptying of contents of the stomach through the mouth. Vomiting can also occur without any underlying diseases like pregnancy, hangovers, overeating, and motion sickness. Nausea or vomiting may be triggered by many factors, including food poisoning, gastritis (inflammation of the stomach lining), an ulcer, or bulimia (eating disorder).

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Alcohol

Caution

You are recommended to limit or avoid alcohol consumption while taking Granikal 1mg Injection. Alcohol intake, along with Granikal 1mg Injection, may lead to unwanted side effects and cause increased dizziness.

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Pregnancy

Caution

It is not known if Granikal 1mg Injection affects pregnancy. Please inform your doctor if you are pregnant or planning pregnancy before receiving Granikal 1mg Injection.

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Breast Feeding

Caution

It is not known if this medicine passes into breast milk. Please inform your doctor before taking Granikal 1mg Injection if you are a nursing mother.

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Driving

Caution

Granikal 1mg Injection may make you feel dizzy, affecting your mental ability. Do not drive or operate machinery if you experience dizziness.

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Liver

Caution

Granikal 1mg Injection should be used with caution if you have liver disease. Please inform your doctor if you have a history of liver impairment before starting Granikal 1mg Injection.

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Kidney

Caution

Granikal 1mg Injection should be used with caution if you have kidney problems. Please inform your doctor if you have a history of kidney impairment/kidney disease.

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Children

Caution

Safety and efficacy of Granikal 1mg Injection have not been established in children below 2 years of age.

Manufacturer/Marketer address

554 ,Near City Police station ,Chura Bazaar, karnal, 132001, Haryana, India
Other Info - GR18138

Author Details

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FAQs

Granikal 1mg Injection is used to treat Nausea and vomiting.
Granikal 1mg Injection contains Granisetron, an anti-emetic drug. It is a serotonin blocker that blocks the activity of serotonin, a chemical messenger that induces nausea and vomiting after treatments like chemotherapy and radiation therapy. Thus, Granikal 1mg Injection relieves post-operative nausea and vomiting symptoms.
Granikal 1mg Injection may cause constipation as one of its side effects. You can avoid it by including high-fibre food in your diet that improves your digestion. Limit the intake of alcohol to manage your constipation.
Granikal 1mg Injection should be used with caution if you have recent stomach/intestinal problems like stomach ache, wind, feeling or being sick, difficulty passing stools, heart rhythm disorder, a recent stomach or intestinal surgery, electrolyte imbalance (potassium, sodium or calcium), and liver or kidney diseases.
You are advised to complete the course prescribed by your doctor. Please do not stop taking this medicine unless advised by your doctor since it may lead to recurrent episodes of nausea and vomiting.

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