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Written By ,
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Dec 7, 2024 | 2:19 PM IST

Daunorubitec 20Mg Inj is an antineoplastic medicine used in the treatment of cancer. It contains Daunorubicin, which belongs to the class of anthracycline topoisomerase inhibitors. It inhibits the topoisomerase II enzyme by intercalating the DNA base pairs. This causes double helix DNA to be uncoiled, thereby destroying DNA and RNA synthesis. Thus, Daunorubitec 20Mg Inj stops the multiplication of abnormal cells, leads to the growth of cells in an unbalanced way, and causes cancer cell death.

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Prescription drug

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Synonym

DAUNORUBICIN HYDROCHLORIDE

Manufacturer/Marketer

United Biotech Pvt Ltd

Consume Type

PARENTERAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About Daunorubitec 20Mg Inj

Daunorubitec 20Mg Inj is an antineoplastic medicine used in the treatment of cancer. Cancer is a disease where the cells grow abnormally and divide uncontrollably. Daunorubitec 20Mg Inj helps to induce remission of nonlymphocytic leukemia (myelogenous, monocytic, erythroid) and acute lymphocytic leukemia. Leukemia, also known as blood cancer, is the cancer of blood cells or blood-forming tissues. It causes excessive production of immature white blood cells by the bone marrow and reduces the body’s ability to fight infections.

Daunorubitec 20Mg Inj contains Daunorubicin, which belongs to the class of anthracycline topoisomerase inhibitors. It inhibits the topoisomerase II enzyme by intercalating the DNA base pairs. This causes double helix DNA to be uncoiled, thereby destroying the DNA and RNA synthesis. Thus, Daunorubitec 20Mg Inj stops the multiplication of abnormal cells, leads to the growth of cells in an unbalanced way and causes cancer cell death.

Daunorubitec 20Mg Inj may cause certain side effects such as vomiting, nausea, mouth ulcers, loss of appetite, diarrhea, dizziness, weakness, fever, chills, and pain at the site of injection. Most of these side effects of Daunorubitec 20Mg Inj do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor. Daunorubitec 20Mg Inj is a parenteral preparation and will be administered by the oncology doctor. Hence, do not self-administer. Your doctor will decide the dose of the medicine based on the severity of the condition.

Daunorubitec 20Mg Inj should be avoided if you are allergic to it or any other component present in it. Inform your doctor about your complete medical and medication history before starting treatment with Daunorubitec 20Mg Inj. Daunorubitec 20Mg Inj is contraindicated for pregnant women and breastfeeding women due to serious embryo-fetal toxicity. Inform your doctor if you are pregnant, planning to become pregnant or breastfeeding. Inform your doctor if you have /had any pre-existing liver or kidney disease. Avoid alcohol consumption with Daunorubitec 20Mg Inj as it may increase the risk of liver damage. This medicine may be recommended for use in children only if the benefits outweigh the risks.

Uses of Daunorubitec 20Mg Inj

Treatment of lymphocytic leukemia, and Acute non-lymphocytic leukemia

Medicinal Benefits

Daunorubitec 20Mg Inj contains Daunorubicin, which belongs to the class of anthracycline topoisomerase inhibitors. It inhibits the topoisomerase II enzyme by intercalating the DNA base pairs. This causes double helix DNA to be uncoiled, thereby destroying the DNA and RNA synthesis. Thus, Daunorubitec 20Mg Inj stops the multiplication of abnormal cells, leads to the growth of cells in an unbalanced way and causes the death of cells.

Directions for Use

Your doctor will administer Daunorubitec 20Mg Inj. Hence, do not self-administer.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Daunorubitec 20Mg Inj

  • Vomiting
  • Nausea
  • Mouth ulcers
  • Loss of appetite
  • Diarrhoea
  • Dizziness
  • Weakness
  • Injection site reactions
  • Pain at the site of injection

Drug Warnings

Daunorubitec 20Mg Inj should be avoided if you are allergic to it or any other component present in it. Inform your doctor about your complete medical and medication history before starting treatment with Daunorubitec 20Mg Inj. Daunorubitec 20Mg Inj is contraindicated for pregnant women and breastfeeding women due to serious embryo-fetal toxicity. Hence, inform your doctor if you are pregnant, planning to become pregnant or breastfeeding. Inform your doctor if you have /had any pre-existing liver or kidney disease. Avoid alcohol consumption with Daunorubitec 20Mg Inj as it may increase the risk of liver damage. Avoid excessive exposure to sunlight as Daunorubitec 20Mg Inj may cause sensitivity to sunlight. You are advised to use sunscreen and wear protective clothing while going out. If you are about to receive any vaccinations, inform your doctor that you are taking Daunorubitec 20Mg Inj as it may cause infections.

Drug Interactions

Drug-Drug Interactions: Daunorubitec 20Mg Inj may interact with medicines used to treat ulcerative colitis (mesalazine, olsalazine), anti-inflammatory drugs (sulfasalazine), aminoglycosides (gentamicin, amikacin, neomycin), cholera vaccine, typhoid vaccine.

Drug-Food Interactions: Daunorubitec 20Mg Inj may interact with alcohol. Therefore, avoid alcohol consumption with Daunorubitec 20Mg Inj as it may increase the risk of liver damage.

Drug-Disease Interactions: Inform your doctor if you have liver or kidney disease before starting treatment with Daunorubitec 20Mg Inj.

Drug-Drug Interactions Checker List

  • MESALAZINE
  • OLSALAZINE
  • SULFASALAZINE
  • GENTAMICIN
  • NEOMYCIN
  • AMIKACIN
  • CHOLERA VACCINE
  • TYPHOID VACCINE

Habit Forming

No

Diet & Lifestyle Advise

  • Maintain a balanced diet including fruits and vegetables rich in nutrients and low-fat proteins like lean meats, fish and poultry.
  • Drink plenty of water daily while taking Daunorubitec 20Mg Inj as some cancer therapies may cause dehydration.
  • Exercise regularly and maintain a healthy body weight.
  • Regularly wash your hands and avoid contact with people having infections.
  • Quit smoking and alcohol consumption.

Special Advise

  • Regular blood tests are recommended while taking Daunorubitec 20Mg Inj to monitor the number and type of cells in the blood and liver functioning.

Disease/Condition Glossary

Acute lymphocytic leukemia: It is a type of cancer that occurs in the bone marrow and blood. It increases the number of lymphocytes (a type of white blood cell). The symptoms include fever, enlarged liver, bone or joint pain, shortness of breath, weakness, and bleeding from gums or bruises.

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Alcohol

Unsafe

Avoid consumption of alcohol with Daunorubitec 20Mg Inj as it may increase the risk of liver damage.

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Pregnancy

Unsafe

It is not recommended for use in pregnancy as it may harm your foetus. If you are pregnant or planning pregnancy, inform your doctor before receiving Daunorubitec 20Mg Inj.

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Breast Feeding

Unsafe

It is not recommended for use in breastfeeding as it may pass into breast milk and harm your infant. Hence, if you are breastfeeding, inform your doctor before receiving Daunorubitec 20Mg Inj. Your doctor may suggest you stop feeding while on treatment with this medicine.

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Driving

Unsafe

Daunorubitec 20Mg Inj causes dizziness and may alter the ability to drive or operate machines. Hence, avoid driving or operating machines after receiving Daunorubitec 20Mg Inj.

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Liver

Caution

If you have a pre-existing or a history of liver disease, inform your doctor before receiving Daunorubitec 20Mg Inj. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.

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Kidney

Caution

If you have a pre-existing or a history of kidney disease, inform your doctor before receiving Daunorubitec 20Mg Inj. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.

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Children

Safe if prescribed

Daunorubitec 20Mg Inj can be recommended for acute lymphocytic leukemia in children. Please consult your doctor. Your child's doctor may prescribe a suitable dose based on the condition and age of your child. If this medicine is given, the child should be observed carefully for any unwanted effects.

Country of origin

India

Manufacturer/Marketer address

FC/B-1 (Extn.), Mohan Co-operative Industrial Estate Mathura Road, New Delhi - 110 044
Other Info - DAU0003

FAQs

Daunorubitec 20Mg Inj is used to treat lymphocytic leukemia, and Acute non-lymphocytic leukemia.
Daunorubitec 20Mg Inj contains Daunorubicin, which belongs to the class of anthracycline topoisomerase inhibitors. It inhibits the topoisomerase II enzyme by intercalating the DNA base pairs. This causes double helix DNA to be uncoiled, thereby destroying the DNA and RNA synthesis.
Daunorubitec 20Mg Inj may cause embryo-fetal toxicity. Therefore, please consult a doctor before taking Daunorubitec 20Mg Inj if you are planning to become a parent.
If you are about to receive any vaccinations, especially live vaccines such as measles, mumps, rubella and polio vaccines, it is advised to inform your doctor that you are on treatment with Daunorubitec 20Mg Inj as it may cause infections.
Yes, Daunorubitec 20Mg Inj is a vesicant (irritant) which means, it can cause severe tissue damage if it leaks into the surrounding tissues during injection (extravasation).
Daunorubitec 20Mg Inj should be administered by the doctor or nurse through an intravenous route (into a vein). Do not self-administer.
The frequency and duration of treatment may vary depending on your medical condition being treated. Always follow the doctor's instructions regarding the dosing schedule to get full benefits.
The side effects of Daunorubitec 20Mg Inj include mouth ulcers, diarrhoea, vomiting, nausea, loss of appetite, dizziness, weakness, fever, chills, and pain at the site of injection. Consult the doctor if any of these symptoms persist or worsen.

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Keep Refrigerated. Do not freeze.Prepaid payment required.

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