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Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Daunorubitec 20Mg Inj is an antineoplastic medicine used in the treatment of cancer. It contains Daunorubicin, which belongs to the class of anthracycline topoisomerase inhibitors. It inhibits the topoisomerase II enzyme by intercalating the DNA base pairs. This causes double helix DNA to be uncoiled, thereby destroying DNA and RNA synthesis. Thus, Daunorubitec 20Mg Inj stops the multiplication of abnormal cells, leads to the growth of cells in an unbalanced way, and causes cancer cell death.

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Synonym :

DAUNORUBICIN HYDROCHLORIDE

Composition :

DAUNORUBICIN-20MG

Manufacturer/Marketer :

United Biotech Pvt Ltd

Consume Type :

PARENTERAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Daunorubitec 20Mg Inj

Daunorubitec 20Mg Inj is an antineoplastic medicine used in the treatment of cancer. Cancer is a disease where the cells grow abnormally and divide uncontrollably. Daunorubitec 20Mg Inj helps to induce remission of nonlymphocytic leukemia (myelogenous, monocytic, erythroid) and acute lymphocytic leukemia. Leukemia, also known as blood cancer, is the cancer of blood cells or blood-forming tissues. It causes excessive production of immature white blood cells by the bone marrow and reduces the body’s ability to fight infections.

Daunorubitec 20Mg Inj contains Daunorubicin, which belongs to the class of anthracycline topoisomerase inhibitors. It inhibits the topoisomerase II enzyme by intercalating the DNA base pairs. This causes double helix DNA to be uncoiled, thereby destroying the DNA and RNA synthesis. Thus, Daunorubitec 20Mg Inj stops the multiplication of abnormal cells, leads to the growth of cells in an unbalanced way and causes cancer cell death.

Daunorubitec 20Mg Inj may cause certain side effects such as vomiting, nausea, mouth ulcers, loss of appetite, diarrhea, dizziness, weakness, fever, chills, and pain at the site of injection. Most of these side effects of Daunorubitec 20Mg Inj do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor. Daunorubitec 20Mg Inj is a parenteral preparation and will be administered by the oncology doctor. Hence, do not self-administer. Your doctor will decide the dose of the medicine based on the severity of the condition.

Daunorubitec 20Mg Inj should be avoided if you are allergic to it or any other component present in it. Inform your doctor about your complete medical and medication history before starting treatment with Daunorubitec 20Mg Inj. Daunorubitec 20Mg Inj is contraindicated for pregnant women and breastfeeding women due to serious embryo-fetal toxicity. Inform your doctor if you are pregnant, planning to become pregnant or breastfeeding. Inform your doctor if you have /had any pre-existing liver or kidney disease. Avoid alcohol consumption with Daunorubitec 20Mg Inj as it may increase the risk of liver damage. This medicine may be recommended for use in children only if the benefits outweigh the risks.

Uses of Daunorubitec 20Mg Inj

Treatment of lymphocytic leukemia, and Acute non-lymphocytic leukemia

Directions for Use

Your doctor will administer Daunorubitec 20Mg Inj. Hence, do not self-administer.

Medicinal Benefits

Daunorubitec 20Mg Inj contains Daunorubicin, which belongs to the class of anthracycline topoisomerase inhibitors. It inhibits the topoisomerase II enzyme by intercalating the DNA base pairs. This causes double helix DNA to be uncoiled, thereby destroying the DNA and RNA synthesis. Thus, Daunorubitec 20Mg Inj stops the multiplication of abnormal cells, leads to the growth of cells in an unbalanced way and causes the death of cells.

How Daunorubitec 20Mg Inj Works

Daunorubitec 20Mg Inj contains Daunorubicin, which belongs to the class of anthracycline topoisomerase inhibitors. It inhibits the topoisomerase II enzyme by intercalating the DNA base pairs. This causes double helix DNA to be uncoiled, thereby destroying the DNA and RNA synthesis. Thus, Daunorubitec 20Mg Inj stops the multiplication of abnormal cells, leads to the growth of cells in an unbalanced way and causes cancer cell death.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Daunorubitec 20Mg Inj

  • Vomiting
  • Nausea
  • Mouth ulcers
  • Loss of appetite
  • Diarrhoea
  • Dizziness
  • Weakness
  • Injection site reactions
  • Pain at the site of injection

What if I have taken an overdose of Daunorubitec 20Mg Inj

Daunorubitec 20Mg Inj is administered in a hospital setting under the supervision of your doctor or medical personnel. Thus, an overdose is quite improbable. While in the hospital, you will be constantly monitored to ensure that any unpleasant side effects are handled.

Drug Warnings

Daunorubitec 20Mg Inj should be avoided if you are allergic to it or any other component present in it. Inform your doctor about your complete medical and medication history before starting treatment with Daunorubitec 20Mg Inj. Daunorubitec 20Mg Inj is contraindicated for pregnant women and breastfeeding women due to serious embryo-fetal toxicity. Hence, inform your doctor if you are pregnant, planning to become pregnant or breastfeeding. Inform your doctor if you have /had any pre-existing liver or kidney disease. Avoid alcohol consumption with Daunorubitec 20Mg Inj as it may increase the risk of liver damage. Avoid excessive exposure to sunlight as Daunorubitec 20Mg Inj may cause sensitivity to sunlight. You are advised to use sunscreen and wear protective clothing while going out. If you are about to receive any vaccinations, inform your doctor that you are taking Daunorubitec 20Mg Inj as it may cause infections.

Drug-Drug Interactions

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DaunorubicinZiprasidone
Critical
DaunorubicinAmisulpride
Severe

Drug-Drug Interactions

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DaunorubicinZiprasidone
Critical
How does the drug interact with Daunorubitec 20Mg Inj:
Taking Daunorubitec 20Mg Inj with Ziprasidone can increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking Daunorubitec 20Mg Inj with Ziprasidone is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not discontinue any medications without consulting a doctor.
DaunorubicinAmisulpride
Severe
How does the drug interact with Daunorubitec 20Mg Inj:
Using Amisulpride together with Daunorubitec 20Mg Inj can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Daunorubitec 20Mg Inj with Amisulpride together can result in an interaction, but it can be taken if a doctor has advised it. If you have any of these symptoms - like a fast or irregular heartbeat, a heart problem, or feeling dizzy or faint - it's important to let the doctor know. Do not stop using any medications without a doctor's advice.
DaunorubicinSotalol
Severe
How does the drug interact with Daunorubitec 20Mg Inj:
Using Daunorubitec 20Mg Inj together with sotalol can increase the risk or severity of irregular heart rhythms. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Although there is a possible interaction between Sotalol and Daunorubitec 20Mg Inj, you can take these medicines together if prescribed by a doctor. If you experience dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations consult a doctor. Do not stop using any medications without talking to a doctor.
DaunorubicinCeritinib
Severe
How does the drug interact with Daunorubitec 20Mg Inj:
Taking Ceritinib with Daunorubitec 20Mg Inj may increase the risk of an irregular heart rhythm.

How to manage the interaction:
Although there is a interaction between Daunorubitec 20Mg Inj and Ceritinib, but it can be taken if prescribed by a doctor. If you have any symptoms like severe or long-lasting loose stools or vomiting, sudden dizziness or lightheadedness, fainting, difficulty breathing, or heart palpitations, consult a doctor. Don't hesitate to reach out to your doctor if you experience any of these symptoms. Do not discontinue any medications without first consulting your doctor.
DaunorubicinCladribine
Severe
How does the drug interact with Daunorubitec 20Mg Inj:
The combined use of cladribine with Daunorubitec 20Mg Inj can increase the risk of serious infections.

How to manage the interaction:
Taking Daunorubitec 20Mg Inj with Cladribine together can possibly result in an interaction, but it can be taken if your doctor has advised it. If you have any of these symptoms, it's important to contact a doctor right away. These symptoms include complications, infection, fever, chills, diarrhea, sore throat, muscle aches, difficulty breathing, weight loss, and pain or burning when you pee. Do not stop using any medications without talking to a doctor.
DaunorubicinMifepristone
Severe
How does the drug interact with Daunorubitec 20Mg Inj:
Co-administration of Daunorubitec 20Mg Inj with mifepristone may increase the risk of an abnormal heart rate, prolonged treatment with Mifepristone may also cause low potassium levels in the body.

How to manage the interaction:
Taking Daunorubitec 20Mg Inj with mifepristone together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, weakness, tiredness, drowsiness, confusion, painful muscle cramping, nausea, or vomiting, constipation, abdominal cramping, chest pain, and/or swelling in the legs or feet, get medical attention. Do not discontinue any medications without consulting a doctor.
DaunorubicinIvabradine
Severe
How does the drug interact with Daunorubitec 20Mg Inj:
Using ivabradine together with Daunorubitec 20Mg Inj can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Although taking Daunorubitec 20Mg Inj and Ivabradine together can cause an interaction, it can be taken if your doctor has suggested it. It is important to keep a close watch on your heart. If you have any of these symptoms - irregular heart rhythm, heart condition, long qt syndrome from birth, conduction problems, prolonged diarrhea, vomiting, complications, sudden dizziness, feeling lightheaded, fainting, difficulty breathing, or heart palpitations - make sure to call a doctor right away. Do not discontinue any medications without consulting a doctor.
DaunorubicinChloroquine
Severe
How does the drug interact with Daunorubitec 20Mg Inj:
Using chloroquine together with danorubicin can increase the risk of an irregular heart rhythm

How to manage the interaction:
Taking chloroquine and Daunorubitec 20Mg Inj together can possibly result in an interaction, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not discontinue any medications without consulting a doctor.
DaunorubicinNilotinib
Severe
How does the drug interact with Daunorubitec 20Mg Inj:
Coadministration of Daunorubitec 20Mg Inj and Nilotinib can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Daunorubitec 20Mg Inj and Nilotinib together can lead to an interaction, but it can be taken when advised by your doctor. However, if you experience any symptoms like sudden dizziness, shortness of breath, diarrhea, or vomiting, contact your doctor immediately. Do not discontinue any medications without consulting your doctor.
DaunorubicinDisopyramide
Severe
How does the drug interact with Daunorubitec 20Mg Inj:
The combined use of Daunorubitec 20Mg Inj and Disopyramide can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Co-administration of Daunorubitec 20Mg Inj and Disopyramide can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like sudden dizziness, lightheadedness, fainting, shortness of breath, heart palpitations, diarrhea, or vomiting, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Maintain a balanced diet including fruits and vegetables rich in nutrients and low-fat proteins like lean meats, fish and poultry.
  • Drink plenty of water daily while taking Daunorubitec 20Mg Inj as some cancer therapies may cause dehydration.
  • Exercise regularly and maintain a healthy body weight.
  • Regularly wash your hands and avoid contact with people having infections.
  • Quit smoking and alcohol consumption.

Habit Forming

No

Therapeutic Class

ANTINEOPLASTIC

Daunorubitec 20Mg Inj Substitute

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Alcohol

Unsafe

Avoid consumption of alcohol with Daunorubitec 20Mg Inj as it may increase the risk of liver damage.

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Pregnancy

Unsafe

It is not recommended for use in pregnancy as it may harm your foetus. If you are pregnant or planning pregnancy, inform your doctor before receiving Daunorubitec 20Mg Inj.

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Breast Feeding

Unsafe

It is not recommended for use in breastfeeding as it may pass into breast milk and harm your infant. Hence, if you are breastfeeding, inform your doctor before receiving Daunorubitec 20Mg Inj. Your doctor may suggest you stop feeding while on treatment with this medicine.

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Driving

Unsafe

Daunorubitec 20Mg Inj causes dizziness and may alter the ability to drive or operate machines. Hence, avoid driving or operating machines after receiving Daunorubitec 20Mg Inj.

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Liver

Caution

If you have a pre-existing or a history of liver disease, inform your doctor before receiving Daunorubitec 20Mg Inj. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.

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Kidney

Caution

If you have a pre-existing or a history of kidney disease, inform your doctor before receiving Daunorubitec 20Mg Inj. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.

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Children

Safe if prescribed

Daunorubitec 20Mg Inj can be recommended for acute lymphocytic leukemia in children. Please consult your doctor. Your child's doctor may prescribe a suitable dose based on the condition and age of your child. If this medicine is given, the child should be observed carefully for any unwanted effects.

FAQs

Daunorubitec 20Mg Inj is used to treat lymphocytic leukemia, and Acute non-lymphocytic leukemia.
Daunorubitec 20Mg Inj contains Daunorubicin, which belongs to the class of anthracycline topoisomerase inhibitors. It inhibits the topoisomerase II enzyme by intercalating the DNA base pairs. This causes double helix DNA to be uncoiled, thereby destroying the DNA and RNA synthesis.
Daunorubitec 20Mg Inj may cause embryo-fetal toxicity. Therefore, please consult a doctor before taking Daunorubitec 20Mg Inj if you are planning to become a parent.
If you are about to receive any vaccinations, especially live vaccines such as measles, mumps, rubella and polio vaccines, it is advised to inform your doctor that you are on treatment with Daunorubitec 20Mg Inj as it may cause infections.
Yes, Daunorubitec 20Mg Inj is a vesicant (irritant) which means, it can cause severe tissue damage if it leaks into the surrounding tissues during injection (extravasation).
Daunorubitec 20Mg Inj should be administered by the doctor or nurse through an intravenous route (into a vein). Do not self-administer.
The frequency and duration of treatment may vary depending on your medical condition being treated. Always follow the doctor's instructions regarding the dosing schedule to get full benefits.
The side effects of Daunorubitec 20Mg Inj include mouth ulcers, diarrhoea, vomiting, nausea, loss of appetite, dizziness, weakness, fever, chills, and pain at the site of injection. Consult the doctor if any of these symptoms persist or worsen.

Country of origin

India

Manufacturer/Marketer address

FC/B-1 (Extn.), Mohan Co-operative Industrial Estate Mathura Road, New Delhi - 110 044
Other Info - DAU0003

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