DAUNOTEC 20MG INJECTION is an antineoplastic medicine used in the treatment of cancer. Cancer is a disease where the cells grow abnormally and divide uncontrollably. DAUNOTEC 20MG INJECTION helps to induce remission of nonlymphocytic leukemia (myelogenous, monocytic, erythroid) and acute lymphocytic leukemia. Leukemia, also known as blood cancer, is the cancer of blood cells or blood-forming tissues. It causes excessive production of immature white blood cells by the bone marrow and reduces the body’s ability to fight infections.

DAUNOTEC 20MG INJECTION contains Daunorubicin, which belongs to the class of anthracycline topoisomerase inhibitors. It inhibits the topoisomerase II enzyme by intercalating the DNA base pairs. This causes double helix DNA to be uncoiled, thereby destroying the DNA and RNA synthesis. Thus, DAUNOTEC 20MG INJECTION stops the multiplication of abnormal cells, leads to the growth of cells in an unbalanced way and causes cancer cell death.

DAUNOTEC 20MG INJECTION may cause certain side effects such as vomiting, nausea, mouth ulcers, loss of appetite, diarrhea, dizziness, weakness, fever, chills, and pain at the site of injection. Most of these side effects of DAUNOTEC 20MG INJECTION do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor. DAUNOTEC 20MG INJECTION is a parenteral preparation and will be administered by the oncology doctor. Hence, do not self-administer. Your doctor will decide the dose of the medicine based on the severity of the condition.

DAUNOTEC 20MG INJECTION should be avoided if you are allergic to it or any other component present in it. Inform your doctor about your complete medical and medication history before starting treatment with DAUNOTEC 20MG INJECTION. DAUNOTEC 20MG INJECTION is contraindicated for pregnant women and breastfeeding women due to serious embryo-fetal toxicity. Inform your doctor if you are pregnant, planning to become pregnant or breastfeeding. Inform your doctor if you have /had any pre-existing liver or kidney disease. Avoid alcohol consumption with DAUNOTEC 20MG INJECTION as it may increase the risk of liver damage. This medicine may be recommended for use in children only if the benefits outweigh the risks.

DAUNOTEC 20MG INJECTION contains Daunorubicin, which belongs to the class of anthracycline topoisomerase inhibitors. It inhibits the topoisomerase II enzyme by intercalating the DNA base pairs. This causes double helix DNA to be uncoiled, thereby destroying the DNA and RNA synthesis. Thus, DAUNOTEC 20MG INJECTION stops the multiplication of abnormal cells, leads to the growth of cells in an unbalanced way and causes the death of cells.

• Vomiting
• Nausea
• Mouth ulcers
• Loss of appetite
• Diarrhoea
• Dizziness
• Weakness
• Injection site reactions
• Pain at the site of injection

DAUNOTEC 20MG INJECTION should be avoided if you are allergic to it or any other component present in it. Inform your doctor about your complete medical and medication history before starting treatment with DAUNOTEC 20MG INJECTION. DAUNOTEC 20MG INJECTION is contraindicated for pregnant women and breastfeeding women due to serious embryo-fetal toxicity. Hence, inform your doctor if you are pregnant, planning to become pregnant or breastfeeding. Inform your doctor if you have /had any pre-existing liver or kidney disease. Avoid alcohol consumption with DAUNOTEC 20MG INJECTION as it may increase the risk of liver damage. Avoid excessive exposure to sunlight as DAUNOTEC 20MG INJECTION may cause sensitivity to sunlight. You are advised to use sunscreen and wear protective clothing while going out. If you are about to receive any vaccinations, inform your doctor that you are taking DAUNOTEC 20MG INJECTION as it may cause infections.

Drug-Drug Interactions: DAUNOTEC 20MG INJECTION may interact with medicines used to treat ulcerative colitis (mesalazine, olsalazine), anti-inflammatory drugs (sulfasalazine), aminoglycosides (gentamicin, amikacin, neomycin), cholera vaccine, typhoid vaccine.

Drug-Food Interactions: DAUNOTEC 20MG INJECTION may interact with alcohol. Therefore, avoid alcohol consumption with DAUNOTEC 20MG INJECTION as it may increase the risk of liver damage.

Drug-Disease Interactions: Inform your doctor if you have liver or kidney disease before starting treatment with DAUNOTEC 20MG INJECTION.

• MESALAZINE
• OLSALAZINE
• SULFASALAZINE
• GENTAMICIN
• NEOMYCIN
• AMIKACIN
• CHOLERA VACCINE
• TYPHOID VACCINE

• Maintain a balanced diet including fruits and vegetables rich in nutrients and low-fat proteins like lean meats, fish and poultry.
• Drink plenty of water daily while taking DAUNOTEC 20MG INJECTION as some cancer therapies may cause dehydration.
• Exercise regularly and maintain a healthy body weight.
• Regularly wash your hands and avoid contact with people having infections.
• Quit smoking and alcohol consumption.

• Regular blood tests are recommended while taking DAUNOTEC 20MG INJECTION to monitor the number and type of cells in the blood and liver functioning.

Acute lymphocytic leukemia: It is a type of cancer that occurs in the bone marrow and blood. It increases the number of lymphocytes (a type of white blood cell). The symptoms include fever, enlarged liver, bone or joint pain, shortness of breath, weakness, and bleeding from gums or bruises.