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Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Daunocyte 20 mg Injection is an antineoplastic medicine used in the treatment of cancer. It contains Daunorubicin, which belongs to the class of anthracycline topoisomerase inhibitors. It inhibits the topoisomerase II enzyme by intercalating the DNA base pairs. This causes double helix DNA to be uncoiled, thereby destroying DNA and RNA synthesis. Thus, Daunocyte 20 mg Injection stops the multiplication of abnormal cells, leads to the growth of cells in an unbalanced way, and causes cancer cell death.

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Synonym :

DAUNORUBICIN HYDROCHLORIDE

Composition :

DAUNORUBICIN-20MG

Manufacturer/Marketer :

Celon Laboratories Pvt Ltd

Consume Type :

PARENTERAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Daunocyte 20 mg Injection

Daunocyte 20 mg Injection is an antineoplastic medicine used in the treatment of cancer. Cancer is a disease where the cells grow abnormally and divide uncontrollably. Daunocyte 20 mg Injection helps to induce remission of nonlymphocytic leukemia (myelogenous, monocytic, erythroid) and acute lymphocytic leukemia. Leukemia, also known as blood cancer, is the cancer of blood cells or blood-forming tissues. It causes excessive production of immature white blood cells by the bone marrow and reduces the body’s ability to fight infections.

Daunocyte 20 mg Injection contains Daunorubicin, which belongs to the class of anthracycline topoisomerase inhibitors. It inhibits the topoisomerase II enzyme by intercalating the DNA base pairs. This causes double helix DNA to be uncoiled, thereby destroying the DNA and RNA synthesis. Thus, Daunocyte 20 mg Injection stops the multiplication of abnormal cells, leads to the growth of cells in an unbalanced way and causes cancer cell death.

Daunocyte 20 mg Injection may cause certain side effects such as vomiting, nausea, mouth ulcers, loss of appetite, diarrhea, dizziness, weakness, fever, chills, and pain at the site of injection. Most of these side effects of Daunocyte 20 mg Injection do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor. Daunocyte 20 mg Injection is a parenteral preparation and will be administered by the oncology doctor. Hence, do not self-administer. Your doctor will decide the dose of the medicine based on the severity of the condition.

Daunocyte 20 mg Injection should be avoided if you are allergic to it or any other component present in it. Inform your doctor about your complete medical and medication history before starting treatment with Daunocyte 20 mg Injection. Daunocyte 20 mg Injection is contraindicated for pregnant women and breastfeeding women due to serious embryo-fetal toxicity. Inform your doctor if you are pregnant, planning to become pregnant or breastfeeding. Inform your doctor if you have /had any pre-existing liver or kidney disease. Avoid alcohol consumption with Daunocyte 20 mg Injection as it may increase the risk of liver damage. This medicine may be recommended for use in children only if the benefits outweigh the risks.

Uses of Daunocyte 20 mg Injection

Treatment of lymphocytic leukemia, and Acute non-lymphocytic leukemia

Directions for Use

Your doctor will administer Daunocyte 20 mg Injection. Hence, do not self-administer.

Medicinal Benefits

Daunocyte 20 mg Injection contains Daunorubicin, which belongs to the class of anthracycline topoisomerase inhibitors. It inhibits the topoisomerase II enzyme by intercalating the DNA base pairs. This causes double helix DNA to be uncoiled, thereby destroying the DNA and RNA synthesis. Thus, Daunocyte 20 mg Injection stops the multiplication of abnormal cells, leads to the growth of cells in an unbalanced way and causes the death of cells.

How Daunocyte 20 mg Injection Works

Daunocyte 20 mg Injection contains Daunorubicin, which belongs to the class of anthracycline topoisomerase inhibitors. It inhibits the topoisomerase II enzyme by intercalating the DNA base pairs. This causes double helix DNA to be uncoiled, thereby destroying the DNA and RNA synthesis. Thus, Daunocyte 20 mg Injection stops the multiplication of abnormal cells, leads to the growth of cells in an unbalanced way and causes cancer cell death.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Daunocyte 20 mg Injection

  • Vomiting
  • Nausea
  • Mouth ulcers
  • Loss of appetite
  • Diarrhoea
  • Dizziness
  • Weakness
  • Injection site reactions
  • Pain at the site of injection

What if I have taken an overdose of Daunocyte 20 mg Injection

Daunocyte 20 mg Injection is administered in a hospital setting under the supervision of your doctor or medical personnel. Thus, an overdose is quite improbable. While in the hospital, you will be constantly monitored to ensure that any unpleasant side effects are handled.

Drug Warnings

Daunocyte 20 mg Injection should be avoided if you are allergic to it or any other component present in it. Inform your doctor about your complete medical and medication history before starting treatment with Daunocyte 20 mg Injection. Daunocyte 20 mg Injection is contraindicated for pregnant women and breastfeeding women due to serious embryo-fetal toxicity. Hence, inform your doctor if you are pregnant, planning to become pregnant or breastfeeding. Inform your doctor if you have /had any pre-existing liver or kidney disease. Avoid alcohol consumption with Daunocyte 20 mg Injection as it may increase the risk of liver damage. Avoid excessive exposure to sunlight as Daunocyte 20 mg Injection may cause sensitivity to sunlight. You are advised to use sunscreen and wear protective clothing while going out. If you are about to receive any vaccinations, inform your doctor that you are taking Daunocyte 20 mg Injection as it may cause infections.

Diet & Lifestyle Advise

  • Maintain a balanced diet including fruits and vegetables rich in nutrients and low-fat proteins like lean meats, fish and poultry.
  • Drink plenty of water daily while taking Daunocyte 20 mg Injection as some cancer therapies may cause dehydration.
  • Exercise regularly and maintain a healthy body weight.
  • Regularly wash your hands and avoid contact with people having infections.
  • Quit smoking and alcohol consumption.

Habit Forming

No

Therapeutic Class

ANTINEOPLASTIC

Daunocyte 20 mg Injection Substitute

Substitutes safety advice
  • DAUNOTEC 20MG INJECTION

    269.90per tablet
  • Dauneon 20mg Injection 1 ml

    283.50per tablet
  • Daunomycin 20Mg Inj

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  • Daunorubitec 20Mg Inj

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    280.80per tablet
  • Daunoplus 20Mg Inj

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    219.15per tablet
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Alcohol

Unsafe

Avoid consumption of alcohol with Daunocyte 20 mg Injection as it may increase the risk of liver damage.

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Pregnancy

Unsafe

It is not recommended for use in pregnancy as it may harm your foetus. If you are pregnant or planning pregnancy, inform your doctor before receiving Daunocyte 20 mg Injection.

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Breast Feeding

Unsafe

It is not recommended for use in breastfeeding as it may pass into breast milk and harm your infant. Hence, if you are breastfeeding, inform your doctor before receiving Daunocyte 20 mg Injection. Your doctor may suggest you stop feeding while on treatment with this medicine.

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Driving

Unsafe

Daunocyte 20 mg Injection causes dizziness and may alter the ability to drive or operate machines. Hence, avoid driving or operating machines after receiving Daunocyte 20 mg Injection.

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Liver

Caution

If you have a pre-existing or a history of liver disease, inform your doctor before receiving Daunocyte 20 mg Injection. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.

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Kidney

Caution

If you have a pre-existing or a history of kidney disease, inform your doctor before receiving Daunocyte 20 mg Injection. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.

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Children

Safe if prescribed

Daunocyte 20 mg Injection can be recommended for acute lymphocytic leukemia in children. Please consult your doctor. Your child's doctor may prescribe a suitable dose based on the condition and age of your child. If this medicine is given, the child should be observed carefully for any unwanted effects.

FAQs

Daunocyte 20 mg Injection is used to treat lymphocytic leukemia, and Acute non-lymphocytic leukemia.
Daunocyte 20 mg Injection contains Daunorubicin, which belongs to the class of anthracycline topoisomerase inhibitors. It inhibits the topoisomerase II enzyme by intercalating the DNA base pairs. This causes double helix DNA to be uncoiled, thereby destroying the DNA and RNA synthesis.
Daunocyte 20 mg Injection may cause embryo-fetal toxicity. Therefore, please consult a doctor before taking Daunocyte 20 mg Injection if you are planning to become a parent.
If you are about to receive any vaccinations, especially live vaccines such as measles, mumps, rubella and polio vaccines, it is advised to inform your doctor that you are on treatment with Daunocyte 20 mg Injection as it may cause infections.
Yes, Daunocyte 20 mg Injection is a vesicant (irritant) which means, it can cause severe tissue damage if it leaks into the surrounding tissues during injection (extravasation).
Daunocyte 20 mg Injection should be administered by the doctor or nurse through an intravenous route (into a vein). Do not self-administer.
The frequency and duration of treatment may vary depending on your medical condition being treated. Always follow the doctor's instructions regarding the dosing schedule to get full benefits.
The side effects of Daunocyte 20 mg Injection include mouth ulcers, diarrhoea, vomiting, nausea, loss of appetite, dizziness, weakness, fever, chills, and pain at the site of injection. Consult the doctor if any of these symptoms persist or worsen.

Country of origin

India

Manufacturer/Marketer address

Plot No 264, Patrika Nagar Madhapur, Hitech City Hyderabad, Telangana India - 500081
Other Info - DAU0011

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