Sodium Aminosalicylate
About Sodium Aminosalicylate
Sodium Aminosalicylate is used to treat tuberculosis (TB). Tuberculosis is an infectious disease caused by Mycobacterium tuberculosis, primarily affecting the lungs, but it can also spread to other parts of the body, including the kidneys, brain, spine, and bone marrow. Sodium Aminosalicylate is ineffective for treating colds, flu, or other viral infections.
Sodium Aminosalicylate contains sodium aminosalicylate. It works by exerting its bacteriostatic effect against Mycobacterium tuberculosis by competing with PABA for enzymes involved in folate synthesis, thereby suppressing the growth and reproduction of the bacteria, ultimately leading to cell death.
You are advised to take Sodium Aminosalicylate for as long as your doctor has prescribed it for you, depending on your medical condition. Sometimes, you may experience common side effects like diarrhoea, nausea, vomiting, and abdominal pain. Most of these symptoms resolve gradually on their own over time. However, consult the doctor if any of these symptoms persist or worsen.
Do not take Sodium Aminosalicylate if you are pregnant or breastfeeding as it may cause potential risk to the foetus and may pass into breast milk. Avoid driving or operating machinery until you know how Sodium Aminosalicylate affects you. Sodium Aminosalicylate is safe for children if prescribed by the doctor. Avoid alcohol consumption and smoking during treatment with Sodium Aminosalicylate as it may cause unpleasant side effects. Inform your doctor about your health condition and medicines to rule out any side effects/interactions.
Uses of Sodium Aminosalicylate
Medicinal Benefits
Sodium Aminosalicylate belongs to the group of medications called anti-infectives. It is used in combination with other medicines for the treatment of tuberculosis (TB). It works by exerting its bacteriostatic effect against Mycobacterium tuberculosis by competing with PABA for enzymes involved in folate synthesis, thereby suppressing bacterial growth and reproduction, ultimately leading to cell death and helping to clear the infection.
Directions for Use
Take Sodium Aminosalicylate with food to prevent stomach irritation or as advised by your doctor. Dissolve Sodium Aminosalicylate in a required amount of boiled (cooled to room temperature) water and drink it immediately.
Storage
Side Effects of Sodium Aminosalicylate
- Nausea
- Vomiting
- Diarrhoea
- Abdominal pain
Drug Warnings
Inform your doctor if you have any of the following pre-existing medical conditions such as kidney or liver disorders, heart failure, glucose-6-phosphate dehydrogenase deficiency, phenylketonuria, lactose intolerance, stomach ulcers, hypersensitivity to salicylates or sulphonamides, thyroid problems, or if you have been advised to limit your salt intake. Inform your doctor if you have nutritional issues like Vitamin B12 deficiency, iron deficiency, or malabsorption syndrome, as it may worsen these conditions, and you might need Vitamin B12 supplements. Do not take Sodium Aminosalicylate if you are pregnant or breastfeeding or if you have duodenal or stomach ulcer and myxoedema (a chronic disease caused by an underactive thyroid gland). Avoid taking Sodium Aminosalicylate if you have severe kidney insufficiency, severe liver insufficiency, or severe heart failure.
Drug Interactions
Drug-Drug Interactions: Sodium Aminosalicylate may interact with medications such antibiotics (rifampicin, Isoniazid and ethionamide), anti-gout medicines (probenecid, sulfinpyrazone), anti-tuberculosis medicine (aminobenzoate), blood thinners, and cardiac glycosides (digoxin).
Drug-Food Interactions: No interactions were found.
Drug-Disease Interactions: Inform your doctor if you have a history of kidney, heart or liver diseases, stomach ulcers, and thyroid problems.
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
unsafeAvoid consumption of alcohol while taking Sodium Aminosalicylate as it may cause unpleasant side effects.
Pregnancy
unsafeSodium Aminosalicylate should not be taken if you are pregnant as it may cause harm to foetus or unborn baby.
Breast Feeding
unsafeSodium Aminosalicylate should not be taken if you are breastfeeding as it may pass in to breastmilk and might affect the baby.
Driving
consult your doctorDo not drive or operate machinery unless you know how Sodium Aminosalicylate affects you. If you have concerns regarding this, discuss with your doctor.
Liver
cautionSodium Aminosalicylate should be used with caution in patients with liver disorders. Please consult your doctor if you have a liver disorder or any concerns regarding this. Sodium Aminosalicylate is not recommended for patients with severe hepatic impairment, liver cirrhosis and hepatitis (inflammation of the liver).
Kidney
cautionSodium Aminosalicylate should be used with caution in patients with kidney disorders. Please consult your doctor if you have a kidney disorder or any concerns. Sodium Aminosalicylate is not recommended for patients with severe kidney insufficiency.
Children
safe if prescribedSodium Aminosalicylate is safe for children if prescribed by a doctor. The dose and duration may vary depending on the child’s weight and the severity of the child's medical condition.
Habit Forming
Diet & Lifestyle Advise
- Pineapple juice might help soothe the symptoms of cough and cold. It also has anti-inflammatory and mucolytic properties.
- Include foods rich in vitamin C, like kiwi, broccoli, and bell pepper, to help improve the immune system.
- Avoid processed and fried foods.
- Warm ginger tea or warm soup can help relieve cough.
- Avoid foods and drinks containing tyramine or histamine, such as cured meat, matured cheese, soya, tuna, salmon, mackerel, wine, and beer.
- Avoid consumption of alcohol and quit smoking.
Patients Concern
Disease/Condition Glossary
Tuberculosis (TB): Tuberculosis is an infectious disease that affects the lungs, but it can also spread to other body parts such as the kidneys, brain, spine, and bone marrow. It is caused by a bacteria named Mycobacterium tuberculosis. It is a contagious disease which can spread to others through tiny droplets released into the air by a person suffering from tuberculosis. The common symptoms include a cough that lasts for a few weeks, pain while coughing or with normal breathing, unexplained fatigue, fever, night sweats, loss of appetite and weight. People who smoke or consume alcohol, people diagnosed with HIV, and immune system problems are more likely at risk of developing active TB.
FAQs
Sodium Aminosalicylate belongs to the group of medications called anti-infectives used to treat tuberculosis caused by Mycobacterium tuberculosis.
Sodium Aminosalicylate contains sodium aminosalicylate. It exerts its bacteriostatic effect against Mycobacterium tuberculosis by competing with PABA for enzymes involved in folate synthesis. This suppresses bacterial growth and reproduction, ultimately leading to cell death and helping to clear the infection.
Do not stop taking Sodium Aminosalicylate alone without a doctor’s advice. To treat your condition effectively, continue taking Sodium Aminosalicylate for as long as it has been prescribed for you.
Sodium Aminosalicylate should be avoided if you are pregnant or breastfeeding or if you have stomach or duodenal ulcer and myxoedema (a chronic disease caused by an underactive thyroid gland). Avoid taking Sodium Aminosalicylate if you have moderate or severe kidney insufficiency, severe liver insufficiency, or severe heart failure.
Sodium Aminosalicylate may cause side effects such as nausea, vomiting, diarrhoea, and abdominal pain. However, if these side effects persist or worsen, please consult the doctor.
If you miss a dose of Sodium Aminosalicylate, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and take the next scheduled dose at the prescribed time. Do not double the dose.
