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Written By ,
Reviewed By Veda Maddala , M Pharmacy
Last Updated Jan 21, 2025 | 11:55 AM IST

Monopas 1000 mg Tablet is used in the treatment of Tuberculosis (TB) in combination with other medicines. It works by exerting its bacteriostatic effect against Mycobacterium tuberculosis by competing with PABA for enzymes involved in folate synthesis, thereby suppressing bacterial growth and reproduction, ultimately leading to cell death. The common side effects may include nausea, vomiting, diarrhoea and abdominal pain.

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Prescription drug

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Synonym :

SODIUM 4-AMINOSALICYLATE DIHYDRATE

Manufacturer/Marketer :

Macleods Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Monopas 1000 mg Tablet

Monopas 1000 mg Tablet is used to treat tuberculosis (TB). Tuberculosis is an infectious disease caused by Mycobacterium tuberculosis, primarily affecting the lungs, but it can also spread to other parts of the body, including the kidneys, brain, spine, and bone marrow. Monopas 1000 mg Tablet is ineffective for treating colds, flu, or other viral infections.

Monopas 1000 mg Tablet contains sodium aminosalicylate. It works by exerting its bacteriostatic effect against Mycobacterium tuberculosis by competing with PABA for enzymes involved in folate synthesis, thereby suppressing the growth and reproduction of the bacteria, ultimately leading to cell death.

You are advised to take Monopas 1000 mg Tablet for as long as your doctor has prescribed it for you, depending on your medical condition. Sometimes, you may experience common side effects like diarrhoea, nausea, vomiting, and abdominal pain. Most of these symptoms resolve gradually on their own over time. However, consult the doctor if any of these symptoms persist or worsen.

Do not take Monopas 1000 mg Tablet if you are pregnant or breastfeeding as it may cause potential risk to the foetus and may pass into breast milk. Avoid driving or operating machinery until you know how Monopas 1000 mg Tablet affects you. Monopas 1000 mg Tablet is safe for children if prescribed by the doctor. Avoid alcohol consumption and smoking during treatment with Monopas 1000 mg Tablet as it may cause unpleasant side effects. Inform your doctor about your health condition and medicines to rule out any side effects/interactions.

Uses of Monopas 1000 mg Tablet

Monopas 1000 mg Tablet is used in the treatment of Tuberculosis (TB).

Medicinal Benefits

Monopas 1000 mg Tablet belongs to the group of medications called anti-infectives. It is used in combination with other medicines for the treatment of tuberculosis (TB). It works by exerting its bacteriostatic effect against Mycobacterium tuberculosis by competing with PABA for enzymes involved in folate synthesis, thereby suppressing bacterial growth and reproduction, ultimately leading to cell death and helping to clear the infection.

Side Effects of Monopas 1000 mg Tablet

  • Nausea
  • Vomiting
  • Diarrhoea
  • Abdominal pain

Directions for Use

Take Monopas 1000 mg Tablet with food to prevent stomach irritation or as advised by your doctor. Dissolve Monopas 1000 mg Tablet in a required amount of boiled (cooled to room temperature) water and drink it immediately.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Inform your doctor if you have any of the following pre-existing medical conditions such as kidney or liver disorders, heart failure, glucose-6-phosphate dehydrogenase deficiency, phenylketonuria, lactose intolerance, stomach ulcers, hypersensitivity to salicylates or sulphonamides, thyroid problems, or if you have been advised to limit your salt intake. Inform your doctor if you have nutritional issues like Vitamin B12 deficiency, iron deficiency, or malabsorption syndrome, as it may worsen these conditions, and you might need Vitamin B12 supplements. Do not take Monopas 1000 mg Tablet if you are pregnant or breastfeeding or if you have duodenal or stomach ulcer and myxoedema (a chronic disease caused by an underactive thyroid gland). Avoid taking Monopas 1000 mg Tablet if you have severe kidney insufficiency, severe liver insufficiency, or severe heart failure.

Therapeutic Class

ANTI- INFECTIVES

Drug-Drug Interactions

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No Drug - Drug interactions found in our data. We may lack specific data on this medicine and are actively working to update our database. Consult your doctor for personalized advice

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Diet & Lifestyle Advise

  • Pineapple juice might help soothe the symptoms of cough and cold. It also has anti-inflammatory and mucolytic properties.
  • Include foods rich in vitamin C, like kiwi, broccoli, and bell pepper, to help improve the immune system.
  • Avoid processed and fried foods.
  • Warm ginger tea or warm soup can help relieve cough.
  • Avoid foods and drinks containing tyramine or histamine, such as cured meat, matured cheese, soya, tuna, salmon, mackerel, wine, and beer.
  • Avoid consumption of alcohol and quit smoking.

Habit Forming

No

How Monopas 1000 mg Tablet Works

Monopas 1000 mg Tablet contains sodium aminosalicylate. It exerts its bacteriostatic effect against Mycobacterium tuberculosis by competing with PABA for enzymes involved in folate synthesis. This suppresses the bacteria's growth and reproduction, ultimately leading to cell death.

What if I have taken an overdose of Monopas 1000 mg Tablet

Do not take more than the recommended dose of Monopas 1000 mg Tablet, as it may cause overdose symptoms like dizziness, diarrhoea, vomiting, and possible development of psychosis. If you suspect you have taken an overdose, seek immediate medical attention.
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Alcohol

Unsafe

Avoid consumption of alcohol while taking Monopas 1000 mg Tablet as it may cause unpleasant side effects.

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Pregnancy

Unsafe

Monopas 1000 mg Tablet should not be taken if you are pregnant as it may cause harm to foetus or unborn baby.

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Breast Feeding

Unsafe

Monopas 1000 mg Tablet should not be taken if you are breastfeeding as it may pass in to breastmilk and might affect the baby.

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Driving

Consult your doctor

Do not drive or operate machinery unless you know how Monopas 1000 mg Tablet affects you. If you have concerns regarding this, discuss with your doctor.

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Liver

Caution

Monopas 1000 mg Tablet should be used with caution in patients with liver disorders. Please consult your doctor if you have a liver disorder or any concerns regarding this. Monopas 1000 mg Tablet is not recommended for patients with severe hepatic impairment, liver cirrhosis and hepatitis (inflammation of the liver).

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Kidney

Caution

Monopas 1000 mg Tablet should be used with caution in patients with kidney disorders. Please consult your doctor if you have a kidney disorder or any concerns. Monopas 1000 mg Tablet is not recommended for patients with severe kidney insufficiency.

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Children

Safe if prescribed

Monopas 1000 mg Tablet is safe for children if prescribed by a doctor. The dose and duration may vary depending on the child’s weight and the severity of the child's medical condition.

Country of origin

India

Manufacturer/Marketer address

Atlanta Arcade, Marol Church Road, Andheri (East), Mumbai - 400059, INDIA.
Other Info - MON0482

Monopas 1000 mg Tablet Substitute

Substitutes safety advice
  • MONOPAS 150MG TABLET

    12.83per tablet
  • Monospas Tablet 6's

    6.08per tablet

FAQs

Monopas 1000 mg Tablet belongs to the group of medications called anti-infectives used to treat tuberculosis caused by Mycobacterium tuberculosis.
Monopas 1000 mg Tablet contains sodium aminosalicylate. It exerts its bacteriostatic effect against Mycobacterium tuberculosis by competing with PABA for enzymes involved in folate synthesis. This suppresses bacterial growth and reproduction, ultimately leading to cell death and helping to clear the infection.
Do not stop taking Monopas 1000 mg Tablet alone without a doctor’s advice. To treat your condition effectively, continue taking Monopas 1000 mg Tablet for as long as it has been prescribed for you.
Monopas 1000 mg Tablet should be avoided if you are pregnant or breastfeeding or if you have stomach or duodenal ulcer and myxoedema (a chronic disease caused by an underactive thyroid gland). Avoid taking Monopas 1000 mg Tablet if you have moderate or severe kidney insufficiency, severe liver insufficiency, or severe heart failure.
Monopas 1000 mg Tablet may cause side effects such as nausea, vomiting, diarrhoea, and abdominal pain. However, if these side effects persist or worsen, please consult the doctor.
If you miss a dose of Monopas 1000 mg Tablet, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and take the next scheduled dose at the prescribed time. Do not double the dose.

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