TIZANIDINE+DICLOFENAC
About
DICLOFENAC+TIZANIDINE is a combination medicine that contains pain relievers and muscle relaxants. It is used to treat spasticity (muscle stiffness and spasms) associated with pain. Pain is a symptom triggered by the nervous system, causing uncomfortable sensations in the body. A muscle spasm occurs due to involuntary contractions of a muscle. A spasm may be a muscle cramp or feel tight or stiff, like a knot.
DICLOFENAC+TIZANIDINE contains Diclofenac (NSAID) and Tizanidine (muscle relaxant). Diclofenac blocks prostaglandins (PGs) that cause pain and swelling. Tizanidine works on the centres of the spinal cord and brain. This helps relieve muscle stiffness and improves muscle movements. As a result, DICLOFENAC+TIZANIDINE helps to reduce muscle stiffness, spasms, and pain.
DICLOFENAC+TIZANIDINE is prescribed medication, and it should be taken as directed by the doctor. In some cases, you may experience common side effects such as feeling or being sick (vomiting), diarrhoea, headaches, drowsiness and ringing in your ears (tinnitus), fluctuations in blood pressure, dry mouth, stomach upsets, and decrease or increase in heart rate. Most of these side effects do not require medical attention and will resolve gradually. However, you are advised to talk to your doctor if you experience these side effects persistently.
Before prescribing DICLOFENAC+TIZANIDINE, inform your doctor about all your allergic or hypersensitivity reactions to medicines or food. Also, tell your doctor about your medical history and other medications you are currently taking to rule out any potential adverse effects. Do not take DICLOFENAC+TIZANIDINE unless recommended by the doctor if you are pregnant or planning pregnancy or breastfeeding. DICLOFENAC+TIZANIDINE may cause dizziness, so drive only if you are alert and focused. DICLOFENAC+TIZANIDINE should not be given to children as safety has not been established. Avoid consuming alcohol while on treatment with DICLOFENAC+TIZANIDINE as it could lead to liver damage.
Uses of TIZANIDINE+DICLOFENAC
Medicinal Benefits
DICLOFENAC+TIZANIDINE contains Diclofenac (NSAID) and Tizanidine (muscle relaxant). Diclofenac inhibits the production of prostaglandins (PGs), which induce pain and swelling. Tizanidine modulates the spinal cord and brain centres. This aids in the relief of muscle stiffness and the improvement of muscle movements. As a result, DICLOFENAC+TIZANIDINE aids in relieving muscle stiffness, spasms, and pain.
Directions for Use
Storage
Side Effects of TIZANIDINE+DICLOFENAC
- Vomiting
- Diarrhoea
- Headaches
- Drowsiness
- Ringing in your ears (tinnitus)
- Fluctuations in blood pressure
- Dry mouth
- Stomach upsets
- Decrease or increase in heart rate
In-Depth Precautions and Warning
Drug Warnings
Do not take DICLOFENAC+TIZANIDINE if you are allergic to its components. Inform your doctor about all your medical conditions, especially if you have/ had hepatotoxicity, hypotension, renal dysfunction or renal toxicities, asthma, fluid retention, GI toxicity, rash, or thrombosis (blood clots). It is not recommended to take DICLOFENAC+TIZANIDINE during pregnancy or whilst breastfeeding. DICLOFENAC+TIZANIDINE may cause drowsiness and dizziness, so drive only if you are alert. DICLOFENAC+TIZANIDINE is not recommended for children as safety and effectiveness have not been established. Do not stop taking DICLOFENAC+TIZANIDINE unless your doctor tells you to. Treatment with DICLOFENAC+TIZANIDINE should be stopped gradually. Stopping treatment suddenly may cause effects such as an increase in heart rate and high blood pressure.
Drug Interactions
Drug-Drug Interactions: DICLOFENAC+TIZANIDINE may interact with certain pain killers (e.g. hydrocodone), anti-depressants (e.g. fluvoxamine, escitalopram), antibiotics (e.g. ciprofloxacin), antihypertensives (e.g. metoprolol), anticoagulant (e.g. apixaban), certain painkillers (e.g. celecoxib), and antiretroviral medicine (e.g. tenofovir).
Drug-Food Interactions: Do not drink alcohol while taking DICLOFENAC+TIZANIDINE.
Drug-Disease Interactions: DICLOFENAC+TIZANIDINE may interact with various disease conditions that include ulcer or perforation, bleeding problems, hepatotoxicity (liver impairment), hypotension, renal dysfunction or toxicities, asthma, fluid retention, GI toxicity, rash, thrombosis (blood clots).
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
unsafeAvoid consumption of alcohol while taking DICLOFENAC+TIZANIDINE as it may cause increased drowsiness. It may also increase the risk of stomach bleeding.
Pregnancy
cautionDICLOFENAC+TIZANIDINE is not recommended for use in pregnant women. If you are pregnant or planning pregnancy, inform your doctor before taking DICLOFENAC+TIZANIDINE.
Breast Feeding
cautionDICLOFENAC+TIZANIDINE is not recommended for use in breastfeeding mothers. If you are breastfeeding, consult your doctor before taking DICLOFENAC+TIZANIDINE.
Driving
cautionDICLOFENAC+TIZANIDINE may cause dizziness or drowsiness. So, do not drive or operate machinery unless you are alert.
Liver
cautionInform your doctor before receiving DICLOFENAC+TIZANIDINE if you have a liver impairment/disorder history. DICLOFENAC+TIZANIDINE is not recommended for use in severely impaired liver function patients.
Kidney
cautionInform your doctor before receiving DICLOFENAC+TIZANIDINE if you have a kidney impairment/disorder history. Your doctor will prescribe only if the benefits outweigh the risks.
Children
unsafeDICLOFENAC+TIZANIDINE is not recommended for children as safety and effectiveness are not established.
Habit Forming
Diet & Lifestyle Advise
- Regular exercise helps muscle stretch, making them less likely to spasm, tear, and sprain. Mild activities such as jogging and walking are helpful for muscle stretching.
- Massages can also be helpful.
- Rest well, and get plenty of sleep.
- Change your position at least every two hours to avoid developing pressure sores.
- Hot or cold therapy can help treat muscle spasms. Apply an ice pack or hot pack on the muscle for 15-20minutes.
- Stay hydrated, drink plenty of water.
Patients Concern
Disease/Condition Glossary
Muscle spasm is the sudden involuntary contractions of the muscle, which can be painful and uncomfortable. When the nerve impulses that control the muscle movements are damaged or interrupted, it could lead to muscle spasms. A spasm may be a twitch in the muscle or feel tight or hard, like a knot.
Pain: Pain is a symptom triggered by the nervous system, causing uncomfortable sensations in the body. Pain may be dull or sharp; it might be constant or may come and go. The tolerance level of pain might vary from person to person. Pain can be generalized (overall body aches) or localized (affecting a specific body area). The common causes of pain include headache, muscle strain, cramps, cuts, bone fractures, and arthritis.
FAQs
DICLOFENAC+TIZANIDINE is used to treat Spasticity (muscle stiffness and spasms) associated with pain.
DICLOFENAC+TIZANIDINE contains Diclofenac (NSAID) and Tizanidine (muscle relaxant). Diclofenac inhibits the production of prostaglandins (PGs), which induce pain and swelling. Tizanidine modulates the spinal cord and brain centres. This aids in the relief of muscle stiffness and the improvement of muscle movements. As a result, DICLOFENAC+TIZANIDINE aids in relieving muscle stiffness, spasms, and pain.
Diarrhoea might be a side-effect of DICLOFENAC+TIZANIDINE. Drink enough fluids and eat non-spicy food if you experience diarrhoea. If you find blood in stools (tarry stools) or if you experience severe diarrhoea, consult your doctor. Do not take anti-diarrheal medicine on your own.
Dry mouth could be a side-effect of DICLOFENAC+TIZANIDINE. Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol, drinking water regularly, and chewing sugar-free gum/candy might stimulate saliva and prevent mouth drying.
Taking DICLOFENAC+TIZANIDINE can elevate symptoms of gastric ulcer and bleeding. So, talk to your doctor before taking DICLOFENAC+TIZANIDINE if you have gastrointestinal bleeding or other bleeding problems before using DICLOFENAC+TIZANIDINE.
It is not advisable to take DICLOFENAC+TIZANIDINE and ciprofloxacin simultaneously. Inform your doctor if you are now using or have recently used ciprofloxacin. Your doctor may advise you to take these two medications at different times.
