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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Sep 30, 2024 | 4:52 PM IST

Tizpa D Tablet is used to treat spasticity (muscle stiffness and spasms) associated with pain. It contains Diclofenac (NSAID) and Tizanidine (muscle relaxant). Diclofenac blocks prostaglandins (PGs) that cause pain and swelling. Tizanidine works on the centres of the spinal cord and brain. This helps relieve muscle stiffness and improves muscle movements. As a result, it helps to reduce muscle stiffness, spasms, and pain.

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Manufacturer/Marketer

Blue Cross Laboratories Pvt Ltd

Consume Type

ORAL

Return Policy

Not Returnable

for this medicine

About Tizpa D Tablet

Tizpa D Tablet is a combination medicine that contains pain relievers and muscle relaxants. It is used to treat spasticity (muscle stiffness and spasms) associated with pain. Pain is a symptom triggered by the nervous system, causing uncomfortable sensations in the body. A muscle spasm occurs due to involuntary contractions of a muscle. A spasm may be a muscle cramp or feel tight or stiff, like a knot.

Tizpa D Tablet contains Diclofenac (NSAID) and Tizanidine (muscle relaxant). Diclofenac blocks prostaglandins (PGs) that cause pain and swelling. Tizanidine works on the centres of the spinal cord and brain. This helps relieve muscle stiffness and improves muscle movements. As a result, Tizpa D Tablet helps to reduce muscle stiffness, spasms, and pain.

Tizpa D Tablet is prescribed medication, and it should be taken as directed by the doctor. In some cases, you may experience common side effects such as feeling or being sick (vomiting), diarrhoea, headaches, drowsiness and ringing in your ears (tinnitus), fluctuations in blood pressure, dry mouth, stomach upsets, and decrease or increase in heart rate. Most of these side effects do not require medical attention and will resolve gradually. However, you are advised to talk to your doctor if you experience these side effects persistently.

Before prescribing Tizpa D Tablet, inform your doctor about all your allergic or hypersensitivity reactions to medicines or food. Also, tell your doctor about your medical history and other medications you are currently taking to rule out any potential adverse effects. Do not take Tizpa D Tablet unless recommended by the doctor if you are pregnant or planning pregnancy or breastfeeding. Tizpa D Tablet may cause dizziness, so drive only if you are alert and focused. Tizpa D Tablet should not be given to children as safety has not been established. Avoid consuming alcohol while on treatment with Tizpa D Tablet as it could lead to liver damage.

Uses of Tizpa D Tablet

Treatment of Spasticity (muscle stiffness and spasms) associated with pain.

Medicinal Benefits

Tizpa D Tablet contains Diclofenac (NSAID) and Tizanidine (muscle relaxant). Diclofenac inhibits the production of prostaglandins (PGs), which induce pain and swelling. Tizanidine modulates the spinal cord and brain centres. This aids in the relief of muscle stiffness and the improvement of muscle movements. As a result, Tizpa D Tablet aids in relieving muscle stiffness, spasms, and pain.

Directions for Use

Swallow the tablet as a whole with a glass of water; do not chew or break it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Tizpa D Tablet

  • Vomiting
  • Diarrhoea
  • Headaches
  • Drowsiness
  • Ringing in your ears (tinnitus)
  • Fluctuations in blood pressure
  • Dry mouth
  • Stomach upsets
  • Decrease or increase in heart rate

Drug Warnings

Do not take Tizpa D Tablet if you are allergic to its components. Inform your doctor about all your medical conditions, especially if you have/ had hepatotoxicity, hypotension, renal dysfunction or renal toxicities, asthma, fluid retention, GI toxicity, rash, or thrombosis (blood clots). It is not recommended to take Tizpa D Tablet during pregnancy or whilst breastfeeding. Tizpa D Tablet may cause drowsiness and dizziness, so drive only if you are alert. Tizpa D Tablet is not recommended for children as safety and effectiveness have not been established. Do not stop taking Tizpa D Tablet unless your doctor tells you to. Treatment with Tizpa D Tablet should be stopped gradually. Stopping treatment suddenly may cause effects such as an increase in heart rate and high blood pressure.

Drug Interactions

Drug-Drug Interactions: Tizpa D Tablet may interact with certain pain killers (e.g. hydrocodone), anti-depressants (e.g. fluvoxamine, escitalopram), antibiotics (e.g. ciprofloxacin), antihypertensives (e.g. metoprolol), anticoagulant (e.g. apixaban), certain painkillers (e.g. celecoxib), and antiretroviral medicine (e.g. tenofovir).

Drug-Food Interactions: Do not drink alcohol while taking Tizpa D Tablet.

Drug-Disease Interactions: Tizpa D Tablet may interact with various disease conditions that include ulcer or perforation, bleeding problems, hepatotoxicity (liver impairment), hypotension, renal dysfunction or toxicities, asthma, fluid retention, GI toxicity, rash, thrombosis (blood clots).

Drug-Drug Interactions Checker List

  • HYDROCODONE
  • FLUVOXAMINE
  • ESCITALOPRAM
  • METOPROLOL
  • APIXABAN
  • CELECOXIB
  • TENOFOVIR

Habit Forming

No

Diet & Lifestyle Advise

  • Regular exercise helps muscle stretch, making them less likely to spasm, tear, and sprain. Mild activities such as jogging and walking are helpful for muscle stretching.
  • Massages can also be helpful.
  • Rest well, and get plenty of sleep.
  • Change your position at least every two hours to avoid developing pressure sores.
  • Hot or cold therapy can help treat muscle spasms. Apply an ice pack or hot pack on the muscle for 15-20minutes.
  • Stay hydrated, drink plenty of water.

Disease/Condition Glossary

Muscle spasm is the sudden involuntary contractions of the muscle, which can be painful and uncomfortable. When the nerve impulses that control the muscle movements are damaged or interrupted, it could lead to muscle spasms. A spasm may be a twitch in the muscle or feel tight or hard, like a knot.

Pain: Pain is a symptom triggered by the nervous system, causing uncomfortable sensations in the body. Pain may be dull or sharp; it might be constant or may come and go. The tolerance level of pain might vary from person to person. Pain can be generalized (overall body aches) or localized (affecting a specific body area). The common causes of pain include headache, muscle strain, cramps, cuts, bone fractures, and arthritis.

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Alcohol

Unsafe

Avoid consumption of alcohol while taking Tizpa D Tablet as it may cause increased drowsiness. It may also increase the risk of stomach bleeding.

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Pregnancy

Caution

Tizpa D Tablet is not recommended for use in pregnant women. If you are pregnant or planning pregnancy, inform your doctor before taking Tizpa D Tablet.

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Breast Feeding

Caution

Tizpa D Tablet is not recommended for use in breastfeeding mothers. If you are breastfeeding, consult your doctor before taking Tizpa D Tablet.

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Driving

Caution

Tizpa D Tablet may cause dizziness or drowsiness. So, do not drive or operate machinery unless you are alert.

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Liver

Caution

Inform your doctor before receiving Tizpa D Tablet if you have a liver impairment/disorder history. Tizpa D Tablet is not recommended for use in severely impaired liver function patients.

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Kidney

Caution

Inform your doctor before receiving Tizpa D Tablet if you have a kidney impairment/disorder history. Your doctor will prescribe only if the benefits outweigh the risks.

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Children

Unsafe

Tizpa D Tablet is not recommended for children as safety and effectiveness are not established.

Country of origin

India

Manufacturer/Marketer address

27, Mirza Galib Street, Kolkata 700 016, West Bengal, India.
Other Info - TI76497

Author Details

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FAQs

Tizpa D Tablet is used to treat Spasticity (muscle stiffness and spasms) associated with pain.
Tizpa D Tablet contains Diclofenac (NSAID) and Tizanidine (muscle relaxant). Diclofenac inhibits the production of prostaglandins (PGs), which induce pain and swelling. Tizanidine modulates the spinal cord and brain centres. This aids in the relief of muscle stiffness and the improvement of muscle movements. As a result, Tizpa D Tablet aids in relieving muscle stiffness, spasms, and pain.
Diarrhoea might be a side-effect of Tizpa D Tablet. Drink enough fluids and eat non-spicy food if you experience diarrhoea. If you find blood in stools (tarry stools) or if you experience severe diarrhoea, consult your doctor. Do not take anti-diarrheal medicine on your own.
Dry mouth could be a side-effect of Tizpa D Tablet. Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol, drinking water regularly, and chewing sugar-free gum/candy might stimulate saliva and prevent mouth drying.
Taking Tizpa D Tablet can elevate symptoms of gastric ulcer and bleeding. So, talk to your doctor before taking Tizpa D Tablet if you have gastrointestinal bleeding or other bleeding problems before using Tizpa D Tablet.
It is not advisable to take Tizpa D Tablet and ciprofloxacin simultaneously. Inform your doctor if you are now using or have recently used ciprofloxacin. Your doctor may advise you to take these two medications at different times.

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