Tramadol+acetaminophen
About Tramadol+acetaminophen
Acetaminophen+tramadol belongs to a class of drugs called analgesics (pain killers) primarily used to treat moderate to severe pain. Pain is an unpleasant sensation caused by an injury or illness. Pain may be acute (short term) or chronic (long term). It can be general (overall body pains) or localized (pain in a specific area of the body).
Acetaminophen+tramadol is a combination of two drugs, namely: Tramadol (opioid analgesic) and Acetaminophen (analgesic and antipyretic). Tramadol works by mimicking the action of endorphins (pain-reducing chemicals) in the brain and spinal cord. Thereby inhibits the transmission of pain signals from nerves to the brain. Also, it improves the effect of serotonin and noradrenaline (chemical messengers in the brain and spinal cord) and helps in relieving pain. Acetaminophen is an analgesic (relieves pain) and antipyretic (reduces fever) that works by inhibiting the production of certain chemical messengers in the brain known as prostaglandins that are responsible for pain and fever.
Take Acetaminophen+tramadol as prescribed by your doctor. You are advised to take Acetaminophen+tramadol for as long as your doctor has prescribed it for you based on your medical condition. In some cases, you may experience drowsiness, nausea, dizziness, headache, vomiting, dry mouth, constipation, excessive sweating, shaking, confusion or mood changes. Most of these side effects of Acetaminophen+tramadol do not require medical attention and gradually resolve over time. However, if the side effects worsen or persist, please consult your doctor.
If you are allergic to Acetaminophen+tramadol or any other medicines, please tell your doctor. Acetaminophen+tramadol is not recommended for children below 12 years of age, as the safety and effectiveness were not established. Avoid taking Acetaminophen+tramadol if you are pregnant as it may cause withdrawal symptoms in the newborn baby. Acetaminophen+tramadol may be excreted in human milk. Please consult a doctor if you are breastfeeding. It is an offence to drive if Acetaminophen+tramadol affects you. Therefore, avoid driving if you feel drowsy or dizzy after taking Acetaminophen+tramadol. Avoid alcohol consumption with Acetaminophen+tramadol as it may increase drowsiness.
Uses of Tramadol+acetaminophen
Medicinal Benefits
Acetaminophen+tramadol is a combination of two drugs: Tramadol and Acetaminophen to treat moderate to severe pain. Tramadol mimics the action of endorphins (pain-reducing chemicals) in the brain and spinal cord. Thereby inhibits the transmission of pain signals from nerves to brain. Also, it improves the effect of serotonin and noradrenaline (chemical messengers in the brain and spinal cord) and helps in relieving pain. Acetaminophen is an analgesic (relieves pain) and antipyretic (reduces fever) that inhibits the production of certain chemical messengers in the brain known as prostaglandins responsible for pain and fever.
Directions for Use
Storage
Side Effects of Tramadol+acetaminophen
- Drowsiness
- Nausea
- Dizziness
- Headache
- Vomiting
- Dry mouth
- Constipation
- Excessive sweating
- Shaking
- Confusion
- Mood changes
Drug Warnings
If you are allergic to Acetaminophen+tramadol or any other medicines, please tell your doctor. Acetaminophen+tramadol is not recommended for children below 12 years of age, as the safety and effectiveness were not established. Avoid taking Acetaminophen+tramadol if you are pregnant as it may cause withdrawal symptoms in the newborn baby. Acetaminophen+tramadol may be excreted in human milk. Please consult a doctor if you are breastfeeding. If you have fits, asthma, severe lung problems, drug dependence, liver or kidney problems, inform your doctor before taking Acetaminophen+tramadol. It is an offence to drive if Acetaminophen+tramadol affects you. Therefore, avoid driving if you feel drowsy or dizzy after taking Acetaminophen+tramadol. Avoid alcohol consumption with Acetaminophen+tramadol as it may increase drowsiness. Do not take Acetaminophen+tramadol if you are taking pain relievers, sleeping pills, or taking medicines such as linezolid, phenelzine, selegiline, rasagiline, isocarboxazid, tranylcypromine and methylene blue injection in the past 14 days. Inform your doctor immediately if you experience any sleep-related breathing problems such as sleep apnoea (breathing stops and starts repeatedly) while taking Acetaminophen+tramadol.
Drug Interactions
Drug-Drug Interactions: Acetaminophen+tramadol may interact with anticonvulsants (carbamazepine, pregabalin), opioid pain killers (pentazocine, buprenorphine, nalbuphine, morphine), cough medication (codeine), muscle relaxant (baclofen), blood thinners (warfarin, phenprocoumon), antiemetic drugs (ondansetron, metoclopramide, domperidone), high cholesterol lowering medicine (cholestyramine), sedative-hypnotics (zolpidem), pain relievers (celecoxib), antidepressants (duloxetine, escitalopram), and anti-anxiety drugs (alprazolam).
Drug- Food Interactions: Avoid foods rich in carbohydrates, pectin including jellies, cabbage, Brussels sprouts and broccoli as Acetaminophen+tramadol may interact with these foods. Acetaminophen+tramadol may interact with grapefruit juice. Therefore, avoid intake of grapefruit juice with Acetaminophen+tramadol as it may increase Acetaminophen+tramadol levels in the body. Also, avoid alcohol consumption while taking Acetaminophen+tramadol as it may increase drowsiness.
Drug-Disease Interactions: If you have fits, asthma, severe lung problems, severe headaches associated with vomiting, drug dependence, liver or kidney problems or if you have recently suffered from shock or head injury, inform your doctor before taking Acetaminophen+tramadol.
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
unsafeAvoid consumption of alcohol with Acetaminophen+tramadol as it may cause drowsiness.
Pregnancy
unsafeAcetaminophen+tramadol is not recommended for pregnant women as it may cause withdrawal symptoms in the newborn baby. However, please consult your doctor if you are pregnant.
Breast Feeding
cautionAcetaminophen+tramadol may be excreted in breast milk and cause adverse effects in the baby. However, please consult a doctor if you are breastfeeding.
Driving
unsafeAcetaminophen+tramadol may cause dizziness or drowsiness in some people. It is an offence to drive if Acetaminophen+tramadol affects you. Therefore, avoid driving if you feel drowsy or dizzy after taking Acetaminophen+tramadol.
Liver
cautionTake Acetaminophen+tramadol with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required. Avoid taking Acetaminophen+tramadol if you have severe liver insufficiency.
Kidney
cautionTake Acetaminophen+tramadol with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required. Avoid taking Acetaminophen+tramadol if you have severe kidney insufficiency.
Children
unsafeAcetaminophen+tramadol is not recommended for children below 12 years of age, as the safety and effectiveness were not established.
Habit Forming
Diet & Lifestyle Advise
- Do regular exercises such as swimming or walking.
- Drink plenty of water while taking Acetaminophen+tramadol to avoid dry mouth.
- Maintain a fibre rich diet and eat plenty of fresh fruits and vegetables to avoid constipation while taking Acetaminophen+tramadol.
- Avoid consumption of alcohol and quit smoking.
Special Advise
- Patients with severe liver or kidney insufficiency should avoid taking Acetaminophen+tramadol.
- Do not give Acetaminophen+tramadol to others. Use Acetaminophen+tramadol only when prescribed by a doctor and avoid frequent or high doses as it may cause addiction.
- Please do not stop taking Acetaminophen+tramadol suddenly as it may cause withdrawal symptoms such as difficulty in sleeping, anxiety, nervousness, shaking, stomach or bowel disorders or make you overactive. Therefore, take Acetaminophen+tramadol for as long as your doctor has prescribed it.
Patients Concern
Disease/Condition Glossary
Pain is an unpleasant sensation caused by an injury or illness. Pain may be acute (short term) or chronic (long term). It can be general (overall body pains) or localized (pain in a specific area of the body). Pain is highly subjective as some people have a high tolerance for pain while others have a low tolerance. Although pain is inconvenient and unpleasant, it hints about causes when something is wrong in the body. Pain may be caused due to cramps, headache, bone fractures, stomach pain, arthritis (swelling of one or more joints), muscle strain or overuse, cuts, flu, irritable bowel syndrome (an intestinal disorder causing stomach pain, diarrhoea or constipation) and fibromyalgia (muscle pain with stiffness and tenderness).
FAQs
Acetaminophen+tramadol is used to treat moderate to severe pain.
Acetaminophen+tramadol contains Tramadol and Acetaminophen. Tramadol is an opioid analgesic that works by mimicking the action of endorphins (pain-reducing chemicals) in the brain and spinal cord. Thereby, inhibits the transmission of pain signals from nerves to the brain. Also, it improves the effect of serotonin and noradrenaline (chemical messengers in the brain and spinal cord) and helps in relieving pain. Acetaminophen is an analgesic (relieves pain) and antipyretic (reduces fever) that works by inhibiting the production of certain chemical messengers in the brain known as prostaglandins that are responsible for pain and fever.
Acetaminophen+tramadol may cause dry mouth as a common side effect. It is not necessary for everyone taking Acetaminophen+tramadol to experience this side effect. However, drink plenty of water, suck on sugar candy or chew sugar-free gum to prevent such side effects while taking Acetaminophen+tramadol. If the condition worsens or persist, please consult a doctor.
Acetaminophen+tramadol should be used with caution in patients suffering from fits as it may worsen the condition. Therefore, it is recommended to inform your doctor if you ever had fits before taking Acetaminophen+tramadol.
No, you are not recommended to take Acetaminophen+tramadol with antidepressants (medicines used to treat depression), and antipsychotics (medicines used to treat bipolar disorder and psychosis) as co-administration of these medicines with Acetaminophen+tramadol may increase the risk of fits. However, please consult a doctor before taking Acetaminophen+tramadol with other medicines.
Acetaminophen+tramadol may cause addiction, especially if taken for a prolonged time. Therefore, Acetaminophen+tramadol should be given only for a short duration under strict medical supervision, particularly to patients who are susceptible to drug abuse. Take Acetaminophen+tramadol only as a doctor advised as overuse or misuse of Acetaminophen+tramadol can lead to overdose and cause severe adverse effects.
You are not recommended to take Acetaminophen+tramadol with warfarin as co-administration of these two medicines may increase bleeding risk more easily. However, if you are supposed to use these medicines together, you are advised to contact your doctor so that the dose may be adjusted appropriately to use safely.
Acetaminophen+tramadol may cause withdrawal symptoms such as difficulty sleeping, anxiety, nervousness, shaking, stomach or bowel disorders, or making you overactive when you stop taking Acetaminophen+tramadol suddenly. Therefore, if you experience any difficulty while taking Acetaminophen+tramadol, do not stop taking suddenly and consult your doctor so that the dose may be reduced gradually to avoid withdrawal symptoms.
