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Written By Veda Maddala , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
Last Updated Oct 9, 2024 | 12:38 PM IST
Tramazac-P Tablet is used to treat moderate to severe pain. It contains Tramadol and Acetaminophen which work by inhibiting the transmission of pain signals from nerves to the brain and blocking the chemical messengers that cause pain. In some cases, this medicine may cause side effects such as drowsiness, nausea, dizziness, headache, vomiting, dry mouth, constipation, excessive sweating, shaking, confusion or mood changes. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.
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Prescription drug

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Manufacturer/Marketer

Zydus Healthcare Ltd

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About Tramazac-P Tablet

Tramazac-P Tablet belongs to a class of drugs called analgesics (pain killers) primarily used to treat moderate to severe pain. Pain is an unpleasant sensation caused by an injury or illness. Pain may be acute (short term) or chronic (long term). It can be general (overall body pains) or localized (pain in a specific area of the body).

Tramazac-P Tablet is a combination of two drugs, namely: Tramadol (opioid analgesic) and Acetaminophen (analgesic and antipyretic). Tramadol works by mimicking the action of endorphins (pain-reducing chemicals) in the brain and spinal cord. Thereby inhibits the transmission of pain signals from nerves to the brain. Also, it improves the effect of serotonin and noradrenaline (chemical messengers in the brain and spinal cord) and helps in relieving pain. Acetaminophen is an analgesic (relieves pain) and antipyretic (reduces fever) that works by inhibiting the production of certain chemical messengers in the brain known as prostaglandins that are responsible for pain and fever.

Take Tramazac-P Tablet as prescribed by your doctor. You are advised to take Tramazac-P Tablet for as long as your doctor has prescribed it for you based on your medical condition. In some cases, you may experience drowsiness, nausea, dizziness, headache, vomiting, dry mouth, constipation, excessive sweating, shaking, confusion or mood changes. Most of these side effects of Tramazac-P Tablet do not require medical attention and gradually resolve over time. However, if the side effects worsen or persist, please consult your doctor.

If you are allergic to Tramazac-P Tablet or any other medicines, please tell your doctor. Tramazac-P Tablet is not recommended for children below 12 years of age, as the safety and effectiveness were not established. Avoid taking Tramazac-P Tablet if you are pregnant as it may cause withdrawal symptoms in the newborn baby. Tramazac-P Tablet may be excreted in human milk. Please consult a doctor if you are breastfeeding. It is an offence to drive if Tramazac-P Tablet affects you. Therefore, avoid driving if you feel drowsy or dizzy after taking Tramazac-P Tablet . Avoid alcohol consumption with Tramazac-P Tablet as it may increase drowsiness.

Uses of Tramazac-P Tablet

Treatment of Moderate to severe pain

Medicinal Benefits

Tramazac-P Tablet is a combination of two drugs: Tramadol and Acetaminophen to treat moderate to severe pain. Tramadol mimics the action of endorphins (pain-reducing chemicals) in the brain and spinal cord. Thereby inhibits the transmission of pain signals from nerves to brain. Also, it improves the effect of serotonin and noradrenaline (chemical messengers in the brain and spinal cord) and helps in relieving pain. Acetaminophen is an analgesic (relieves pain) and antipyretic (reduces fever) that inhibits the production of certain chemical messengers in the brain known as prostaglandins responsible for pain and fever.

Directions for Use

Take Tramazac-P Tablet with or without food as advised by your doctor. Swallow it as a whole with a glass of water. Do not crush, chew or break it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Tramazac-P Tablet

  • Drowsiness
  • Nausea
  • Dizziness
  • Headache
  • Vomiting
  • Dry mouth
  • Constipation
  • Excessive sweating
  • Shaking
  • Confusion
  • Mood changes

Drug Warnings

If you are allergic to Tramazac-P Tablet or any other medicines, please tell your doctor. Tramazac-P Tablet is not recommended for children below 12 years of age, as the safety and effectiveness were not established. Avoid taking Tramazac-P Tablet if you are pregnant as it may cause withdrawal symptoms in the newborn baby. Tramazac-P Tablet may be excreted in human milk. Please consult a doctor if you are breastfeeding. If you have fits, asthma, severe lung problems, drug dependence,  liver or kidney problems, inform your doctor before taking Tramazac-P Tablet . It is an offence to drive if Tramazac-P Tablet affects you. Therefore, avoid driving if you feel drowsy or dizzy after taking Tramazac-P Tablet . Avoid alcohol consumption with Tramazac-P Tablet as it may increase drowsiness. Do not take Tramazac-P Tablet if you are taking pain relievers, sleeping pills, or taking medicines such as linezolid, phenelzine, selegiline, rasagiline, isocarboxazid, tranylcypromine and methylene blue injection in the past 14 days. Inform your doctor immediately if you experience any sleep-related breathing problems such as sleep apnoea (breathing stops and starts repeatedly) while taking Tramazac-P Tablet .

Drug Interactions

Drug-Drug Interactions: Tramazac-P Tablet may interact with anticonvulsants (carbamazepine, pregabalin), opioid pain killers (pentazocine, buprenorphine, nalbuphine, morphine), cough medication (codeine), muscle relaxant (baclofen), blood thinners (warfarin, phenprocoumon), antiemetic drugs (ondansetron, metoclopramide, domperidone), high cholesterol lowering medicine (cholestyramine), sedative-hypnotics (zolpidem), pain relievers (celecoxib), antidepressants (duloxetine, escitalopram), and anti-anxiety drugs (alprazolam).

Drug- Food Interactions: Avoid foods rich in carbohydrates, pectin including jellies, cabbage, Brussels sprouts and broccoli as Tramazac-P Tablet may interact with these foods. Tramazac-P Tablet may interact with grapefruit juice. Therefore, avoid intake of grapefruit juice with Tramazac-P Tablet as it may increase Tramazac-P Tablet levels in the body. Also, avoid alcohol consumption while taking Tramazac-P Tablet as it may increase drowsiness.

Drug-Disease Interactions: If you have fits, asthma, severe lung problems, severe headaches associated with vomiting, drug dependence,  liver or kidney problems or if you have recently suffered from shock or head injury, inform your doctor before taking Tramazac-P Tablet .

Drug-Drug Interactions Checker List

  • CARBAMAZEPINE
  • PREGABALIN
  • PENTAZOCIN
  • BUPRENORPHINE
  • MORPHINE
  • CODEINE
  • BACLOFEN
  • WARFARIN
  • PHENPROCOUMON
  • ONDANSETRON
  • METOCLOPRAMIDE
  • DOMPERIDONE
  • CHOLESTYRAMINE
  • ZOLPIDEM
  • CELECOXIB
  • DULOXETINE
  • ESCITALOPRAM
  • ALPRAZOLAM
  • NALBUPHINE

Habit Forming

Yes

Diet & Lifestyle Advise

  • Do regular exercises such as swimming or walking.
  • Drink plenty of water while taking Tramazac-P Tablet to avoid dry mouth.
  • Maintain a fibre rich diet and eat plenty of fresh fruits and vegetables to avoid constipation while taking Tramazac-P Tablet .
  • Avoid consumption of alcohol and quit smoking.

Special Advise

  • Patients with severe liver or kidney insufficiency should avoid taking Tramazac-P Tablet .
  • Do not give Tramazac-P Tablet to others. Use Tramazac-P Tablet only when prescribed by a doctor and avoid frequent or high doses as it may cause addiction.
  • Please do not stop taking Tramazac-P Tablet suddenly as it may cause withdrawal symptoms such as difficulty in sleeping, anxiety, nervousness, shaking, stomach or bowel disorders or make you overactive. Therefore, take Tramazac-P Tablet for as long as your doctor has prescribed it.

Disease/Condition Glossary

Pain is an unpleasant sensation caused by an injury or illness. Pain may be acute (short term) or chronic (long term). It can be general (overall body pains) or localized (pain in a specific area of the body). Pain is highly subjective as some people have a high tolerance for pain while others have a low tolerance. Although pain is inconvenient and unpleasant, it hints about causes when something is wrong in the body. Pain may be caused due to cramps, headache, bone fractures, stomach pain, arthritis (swelling of one or more joints), muscle strain or overuse, cuts, flu, irritable bowel syndrome (an intestinal disorder causing stomach pain, diarrhoea or constipation) and fibromyalgia (muscle pain with stiffness and tenderness).

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Alcohol

Unsafe

Avoid consumption of alcohol with Tramazac-P Tablet as it may cause drowsiness.

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Pregnancy

Unsafe

Tramazac-P Tablet is not recommended for pregnant women as it may cause withdrawal symptoms in the newborn baby. However, please consult your doctor if you are pregnant.

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Breast Feeding

Caution

Tramazac-P Tablet may be excreted in breast milk and cause adverse effects in the baby. However, please consult a doctor if you are breastfeeding.

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Driving

Unsafe

Tramazac-P Tablet may cause dizziness or drowsiness in some people. It is an offence to drive if Tramazac-P Tablet affects you. Therefore, avoid driving if you feel drowsy or dizzy after taking Tramazac-P Tablet .

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Liver

Caution

Take Tramazac-P Tablet with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required. Avoid taking Tramazac-P Tablet if you have severe liver insufficiency.

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Kidney

Caution

Take Tramazac-P Tablet with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required. Avoid taking Tramazac-P Tablet if you have severe kidney insufficiency.

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Children

Unsafe

Tramazac-P Tablet is not recommended for children below 12 years of age, as the safety and effectiveness were not established.

Country of origin

India

Manufacturer/Marketer address

Zydus Tower, Satellite Cross Roads,Ahmedabad – 380015 Gujarat, India
Other Info - TRA0532

Author Details

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FAQs

Tramazac-P Tablet is used to treat moderate to severe pain.
Tramazac-P Tablet contains Tramadol and Acetaminophen. Tramadol is an opioid analgesic that works by mimicking the action of endorphins (pain-reducing chemicals) in the brain and spinal cord. Thereby, inhibits the transmission of pain signals from nerves to the brain. Also, it improves the effect of serotonin and noradrenaline (chemical messengers in the brain and spinal cord) and helps in relieving pain. Acetaminophen is an analgesic (relieves pain) and antipyretic (reduces fever) that works by inhibiting the production of certain chemical messengers in the brain known as prostaglandins that are responsible for pain and fever.
Tramazac-P Tablet may cause dry mouth as a common side effect. It is not necessary for everyone taking Tramazac-P Tablet to experience this side effect. However, drink plenty of water, suck on sugar candy or chew sugar-free gum to prevent such side effects while taking Tramazac-P Tablet . If the condition worsens or persist, please consult a doctor.
Tramazac-P Tablet should be used with caution in patients suffering from fits as it may worsen the condition. Therefore, it is recommended to inform your doctor if you ever had fits before taking Tramazac-P Tablet .
No, you are not recommended to take Tramazac-P Tablet with antidepressants (medicines used to treat depression), and antipsychotics (medicines used to treat bipolar disorder and psychosis) as co-administration of these medicines with Tramazac-P Tablet may increase the risk of fits. However, please consult a doctor before taking Tramazac-P Tablet with other medicines.
Tramazac-P Tablet may cause addiction, especially if taken for a prolonged time. Therefore, Tramazac-P Tablet should be given only for a short duration under strict medical supervision, particularly to patients who are susceptible to drug abuse. Take Tramazac-P Tablet only as a doctor advised as overuse or misuse of Tramazac-P Tablet can lead to overdose and cause severe adverse effects.
You are not recommended to take Tramazac-P Tablet with warfarin as co-administration of these two medicines may increase bleeding risk more easily. However, if you are supposed to use these medicines together, you are advised to contact your doctor so that the dose may be adjusted appropriately to use safely.
Tramazac-P Tablet may cause withdrawal symptoms such as difficulty sleeping, anxiety, nervousness, shaking, stomach or bowel disorders, or making you overactive when you stop taking Tramazac-P Tablet suddenly. Therefore, if you experience any difficulty while taking Tramazac-P Tablet , do not stop taking suddenly and consult your doctor so that the dose may be reduced gradually to avoid withdrawal symptoms.

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