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Written By Veda Maddala , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
Opdol Tablet 10's is used to treat moderate to severe pain. It contains Tramadol and Acetaminophen which work by inhibiting the transmission of pain signals from nerves to the brain and blocking the chemical messengers that cause pain. In some cases, this medicine may cause side effects such as drowsiness, nausea, dizziness, headache, vomiting, dry mouth, constipation, excessive sweating, shaking, confusion or mood changes. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.
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Consume Type :

ORAL

Return Policy :

Not Returnable

About Opdol Tablet 10's

Opdol Tablet 10's belongs to a class of drugs called analgesics (pain killers) primarily used to treat moderate to severe pain. Pain is an unpleasant sensation caused by an injury or illness. Pain may be acute (short term) or chronic (long term). It can be general (overall body pains) or localized (pain in a specific area of the body).

Opdol Tablet 10's is a combination of two drugs, namely: Tramadol (opioid analgesic) and Acetaminophen (analgesic and antipyretic). Tramadol works by mimicking the action of endorphins (pain-reducing chemicals) in the brain and spinal cord. Thereby inhibits the transmission of pain signals from nerves to the brain. Also, it improves the effect of serotonin and noradrenaline (chemical messengers in the brain and spinal cord) and helps in relieving pain. Acetaminophen is an analgesic (relieves pain) and antipyretic (reduces fever) that works by inhibiting the production of certain chemical messengers in the brain known as prostaglandins that are responsible for pain and fever.

Take Opdol Tablet 10's as prescribed by your doctor. You are advised to take Opdol Tablet 10's for as long as your doctor has prescribed it for you based on your medical condition. In some cases, you may experience drowsiness, nausea, dizziness, headache, vomiting, dry mouth, constipation, excessive sweating, shaking, confusion or mood changes. Most of these side effects of Opdol Tablet 10's do not require medical attention and gradually resolve over time. However, if the side effects worsen or persist, please consult your doctor.

If you are allergic to Opdol Tablet 10's or any other medicines, please tell your doctor. Opdol Tablet 10's is not recommended for children below 12 years of age, as the safety and effectiveness were not established. Avoid taking Opdol Tablet 10's if you are pregnant as it may cause withdrawal symptoms in the newborn baby. Opdol Tablet 10's may be excreted in human milk. Please consult a doctor if you are breastfeeding. It is an offence to drive if Opdol Tablet 10's affects you. Therefore, avoid driving if you feel drowsy or dizzy after taking Opdol Tablet 10's. Avoid alcohol consumption with Opdol Tablet 10's as it may increase drowsiness.

Uses of Opdol Tablet 10's

Treatment of Moderate to severe pain

Directions for Use

Take Opdol Tablet 10's with or without food as advised by your doctor. Swallow it as a whole with a glass of water. Do not crush, chew or break it.

Medicinal Benefits

Opdol Tablet 10's is a combination of two drugs: Tramadol and Acetaminophen to treat moderate to severe pain. Tramadol mimics the action of endorphins (pain-reducing chemicals) in the brain and spinal cord. Thereby inhibits the transmission of pain signals from nerves to brain. Also, it improves the effect of serotonin and noradrenaline (chemical messengers in the brain and spinal cord) and helps in relieving pain. Acetaminophen is an analgesic (relieves pain) and antipyretic (reduces fever) that inhibits the production of certain chemical messengers in the brain known as prostaglandins responsible for pain and fever.

How Opdol Tablet 10's Works

Opdol Tablet 10's is a combination of two drugs, namely: Tramadol (opioid analgesic) and Acetaminophen (analgesic and antipyretic). Tramadol works by mimicking the action of endorphins (pain-reducing chemicals) in the brain and spinal cord. Thereby inhibits the transmission of pain signals from nerves to the brain. Also, it improves the effect of serotonin and noradrenaline (chemical messengers in the brain and spinal cord) and helps in relieving pain. Acetaminophen is an analgesic (relieves pain) and antipyretic (reduces fever) that works by inhibiting the production of certain chemical messengers in the brain known as prostaglandins that are responsible for pain and fever.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Opdol Tablet 10's

  • Drowsiness
  • Nausea
  • Dizziness
  • Headache
  • Vomiting
  • Dry mouth
  • Constipation
  • Excessive sweating
  • Shaking
  • Confusion
  • Mood changes

What if I have taken an overdose of Opdol Tablet 10's

Take Opdol Tablet 10's only as prescribed by the physician. Avoid exceeding the recommended dose as it could lead to an overdose. Symptoms of overdose may include severe drowsiness, pinpoint pupils, slow breathing, or no breathing. If you experience these symptoms or suspect you have taken an overdose, seek immediate medical attention.

Drug Warnings

If you are allergic to Opdol Tablet 10's or any other medicines, please tell your doctor. Opdol Tablet 10's is not recommended for children below 12 years of age, as the safety and effectiveness were not established. Avoid taking Opdol Tablet 10's if you are pregnant as it may cause withdrawal symptoms in the newborn baby. Opdol Tablet 10's may be excreted in human milk. Please consult a doctor if you are breastfeeding. If you have fits, asthma, severe lung problems, drug dependence,  liver or kidney problems, inform your doctor before taking Opdol Tablet 10's. It is an offence to drive if Opdol Tablet 10's affects you. Therefore, avoid driving if you feel drowsy or dizzy after taking Opdol Tablet 10's. Avoid alcohol consumption with Opdol Tablet 10's as it may increase drowsiness. Do not take Opdol Tablet 10's if you are taking pain relievers, sleeping pills, or taking medicines such as linezolid, phenelzine, selegiline, rasagiline, isocarboxazid, tranylcypromine and methylene blue injection in the past 14 days. Inform your doctor immediately if you experience any sleep-related breathing problems such as sleep apnoea (breathing stops and starts repeatedly) while taking Opdol Tablet 10's.

Drug-Drug Interactions

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TramadolAlvimopan
Critical
TramadolTranylcypromine
Critical

Drug-Drug Interactions

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TramadolAlvimopan
Critical
How does the drug interact with Opdol Tablet 10's:
Co-administration of Opdol Tablet 10's with Alvimopan can make the side effects worse or more dangerous.

How to manage the interaction:
Taking Alvimopan with Opdol Tablet 10's is not recommended, please consult your doctor before taking it.
TramadolTranylcypromine
Critical
How does the drug interact with Opdol Tablet 10's:
Combining Tranylcypromine with Opdol Tablet 10's can increase the risk of serotonin syndrome (a condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Taking Tranylcypromine with Opdol Tablet 10's is not recommended, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, hallucination(seeing and hearing things that do not exist), fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea. Do not discontinue any medications without consulting your doctor.
TramadolRasagiline
Critical
How does the drug interact with Opdol Tablet 10's:
Taking rasagiline with Opdol Tablet 10's can increase the risk of serotonin syndrome (A condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Taking Opdol Tablet 10's with Rasagiline is not recommended, as it can lead to an interaction, but can be taken if advised by your doctor. However, if you experience any symptoms like severe headache, blurred vision, confusion, seizures, chest pain, nausea or vomiting, sudden numbness or weakness (especially on one side of the body), speech difficulties, fever, sweating, lightheadedness, and fainting, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
TramadolLinezolid
Critical
How does the drug interact with Opdol Tablet 10's:
Co-administration of Linezolid with Opdol Tablet 10's can increase the risk of serotonin syndrome and seizures.

How to manage the interaction:
Taking Linezolid with Opdol Tablet 10's is not recommended, consult a doctor before taking it. Consult a doctor if you experience confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremor, incoordination, stomach cramp, nausea, vomiting, and diarrhea. Do not stop using any medications without talking to a doctor.
TramadolSafinamide
Critical
How does the drug interact with Opdol Tablet 10's:
Taking Safinamide with Opdol Tablet 10's can increase the risk of serotonin syndrome (A condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Taking Safinamide with Opdol Tablet 10's is not recommended as it can possibly result in an interaction, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, hallucination(seeing and hearing things that do not exist), fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and loose stools. Do not discontinue any medications without consulting your doctor.
TramadolPhenelzine
Critical
How does the drug interact with Opdol Tablet 10's:
Combining Phenelzine with Opdol Tablet 10's can increase the risk of serotonin syndrome and seizures.

How to manage the interaction:
Taking Opdol Tablet 10's with Phenelzine is not recommended, please consult your doctor before taking it.
TramadolZiprasidone
Critical
How does the drug interact with Opdol Tablet 10's:
Co-administration of Ziprasidone with Opdol Tablet 10's can increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking Opdol Tablet 10's with Ziprasidone together can possibly result in an interaction, but it can be taken if a doctor has advised it. However, consult a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not discontinue any medications without consulting a doctor.
ParacetamolMipomersen
Severe
How does the drug interact with Opdol Tablet 10's:
Co-administration of Mipomersen with Opdol Tablet 10's may increase the risk or severity of liver injury.

How to manage the interaction:
There may be a possibility of interaction between Opdol Tablet 10's and Mipomersen, but it can be taken if prescribed by a doctor. Do not stop using any medications without talking to a doctor.
ParacetamolValdecoxib
Severe
How does the drug interact with Opdol Tablet 10's:
Co-administration of Opdol Tablet 10's and Valdecoxib may increase the risk or severity of adverse effects.

How to manage the interaction:
Although there is a possible interaction between Opdol Tablet 10's and Valdecoxib, you can take these medicines together if prescribed by a doctor. However, if the side effects worsen, please consult a doctor.
ParacetamolOxazepam
Severe
How does the drug interact with Opdol Tablet 10's:
Co-administration of Opdol Tablet 10's may decrease the excretion rate of Oxazepam which could result in a higher serum level.

How to manage the interaction:
Although there is a possible interaction between Oxazepam and Opdol Tablet 10's, you can take these medicines together if prescribed by a doctor. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Do regular exercises such as swimming or walking.
  • Drink plenty of water while taking Opdol Tablet 10's to avoid dry mouth.
  • Maintain a fibre rich diet and eat plenty of fresh fruits and vegetables to avoid constipation while taking Opdol Tablet 10's.
  • Avoid consumption of alcohol and quit smoking.

Habit Forming

Yes

Therapeutic Class

ANALGESICS

Opdol Tablet 10's Substitute

Substitutes safety advice
  • ULTRAZAC 325MG TABLET

    12.83per tablet
  • MEGA FLEXON TABLET 10'S

    by AYUR

    10.17per tablet
  • Trado Tablet 10's

    by AYUR

    8.91per tablet
  • Vorth TM Tablet 10's

    by AYUR

    13.50per tablet
  • PARTRAM TABLET 10'S

    by AYUR

    7.11per tablet
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Alcohol

Unsafe

Avoid consumption of alcohol with Opdol Tablet 10's as it may cause drowsiness.

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Pregnancy

Unsafe

Opdol Tablet 10's is not recommended for pregnant women as it may cause withdrawal symptoms in the newborn baby. However, please consult your doctor if you are pregnant.

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Breast Feeding

Caution

Opdol Tablet 10's may be excreted in breast milk and cause adverse effects in the baby. However, please consult a doctor if you are breastfeeding.

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Driving

Unsafe

Opdol Tablet 10's may cause dizziness or drowsiness in some people. It is an offence to drive if Opdol Tablet 10's affects you. Therefore, avoid driving if you feel drowsy or dizzy after taking Opdol Tablet 10's.

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Liver

Caution

Take Opdol Tablet 10's with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required. Avoid taking Opdol Tablet 10's if you have severe liver insufficiency.

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Kidney

Caution

Take Opdol Tablet 10's with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required. Avoid taking Opdol Tablet 10's if you have severe kidney insufficiency.

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Children

Unsafe

Opdol Tablet 10's is not recommended for children below 12 years of age, as the safety and effectiveness were not established.

FAQs

Opdol Tablet 10's is used to treat moderate to severe pain.
Opdol Tablet 10's contains Tramadol and Acetaminophen. Tramadol is an opioid analgesic that works by mimicking the action of endorphins (pain-reducing chemicals) in the brain and spinal cord. Thereby, inhibits the transmission of pain signals from nerves to the brain. Also, it improves the effect of serotonin and noradrenaline (chemical messengers in the brain and spinal cord) and helps in relieving pain. Acetaminophen is an analgesic (relieves pain) and antipyretic (reduces fever) that works by inhibiting the production of certain chemical messengers in the brain known as prostaglandins that are responsible for pain and fever.
Opdol Tablet 10's may cause dry mouth as a common side effect. It is not necessary for everyone taking Opdol Tablet 10's to experience this side effect. However, drink plenty of water, suck on sugar candy or chew sugar-free gum to prevent such side effects while taking Opdol Tablet 10's. If the condition worsens or persist, please consult a doctor.
Opdol Tablet 10's should be used with caution in patients suffering from fits as it may worsen the condition. Therefore, it is recommended to inform your doctor if you ever had fits before taking Opdol Tablet 10's.
No, you are not recommended to take Opdol Tablet 10's with antidepressants (medicines used to treat depression), and antipsychotics (medicines used to treat bipolar disorder and psychosis) as co-administration of these medicines with Opdol Tablet 10's may increase the risk of fits. However, please consult a doctor before taking Opdol Tablet 10's with other medicines.
Opdol Tablet 10's may cause addiction, especially if taken for a prolonged time. Therefore, Opdol Tablet 10's should be given only for a short duration under strict medical supervision, particularly to patients who are susceptible to drug abuse. Take Opdol Tablet 10's only as a doctor advised as overuse or misuse of Opdol Tablet 10's can lead to overdose and cause severe adverse effects.
You are not recommended to take Opdol Tablet 10's with warfarin as co-administration of these two medicines may increase bleeding risk more easily. However, if you are supposed to use these medicines together, you are advised to contact your doctor so that the dose may be adjusted appropriately to use safely.
Opdol Tablet 10's may cause withdrawal symptoms such as difficulty sleeping, anxiety, nervousness, shaking, stomach or bowel disorders, or making you overactive when you stop taking Opdol Tablet 10's suddenly. Therefore, if you experience any difficulty while taking Opdol Tablet 10's, do not stop taking suddenly and consult your doctor so that the dose may be reduced gradually to avoid withdrawal symptoms.

Country of origin

India

Manufacturer/Marketer address

3rd Floor, Medicare Center, Karangalpady, Mangalore- 575003
Other Info - OPD0007

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