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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Nov 23, 2024 | 4:27 PM IST

Uniprost 500 mg Tablet 60's is used in combination with prednisone or prednisolone to treat prostate cancer in adult men that has spread to other body parts. It contains Abiraterone, which works by stopping the body from making testosterone, thereby slowing the growth of prostate cancer. It is not for use in women, children, and adolescents. In some cases, Uniprost 500 mg Tablet 60's may cause common side effects such as diarrhoea, urinary tract infection, high blood pressure, low blood potassium, and oedema. If any of the side effects persist or worsen, consult your doctor.

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Prescription drug

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Synonym

ABIRATERONE ACETATE

Consume Type

ORAL

Return Policy

Not Returnable

for this medicine

About Uniprost 500 mg Tablet 60's

Uniprost 500 mg Tablet 60's belongs to the group of medicines called androgen biosynthesis inhibitors that is indicated in combination with prednisone or prednisolone to treat prostate cancer in adult men that have spread to other body parts.

Uniprost 500 mg Tablet 60's contains ‘Abiraterone’ that works by stopping the body from making testosterone, thereby slowing the growth of prostate cancer.

In some cases, Uniprost 500 mg Tablet 60's may cause common side effects such as diarrhoea, urinary tract infection, high blood pressure, low blood potassium, and oedema. If any of the side effects persist or worsen, consult your doctor.

Uniprost 500 mg Tablet 60's is not for use in women, children, and adolescents. Uniprost 500 mg Tablet 60's should not be given in combination with Ra-233 (a radioactive isotope used to treat prostate cancer) due to the increased risk of bone fracture or death. Inform your doctor about your health condition and medications to rule out any side effects/interactions.

Uses of Uniprost 500 mg Tablet 60's

Treatment of Prostate cancer

Medicinal Benefits

Uniprost 500 mg Tablet 60's belongs to the group of medicines called androgen biosynthesis inhibitors, indicated in combination with prednisone or prednisolone to treat prostate cancer in adult men that have spread to other body parts. Uniprost 500 mg Tablet 60's contains ‘Abiraterone’ that works by stopping the body from making testosterone, thereby slowing the growth of prostate cancer. It is indicated in patients with metastatic castration-resistant prostate cancer (CRPC) who have received prior chemotherapy containing docetaxel and metastatic high-risk castration-sensitive prostate cancer (CSPC). Uniprost 500 mg Tablet 60's is prescribed in the early stages of the disease, where it is still responding to hormone therapy. It is used with androgen deprivation therapy (a treatment that lowers testosterone).

Directions for Use

Take this medicine on an empty stomach, i.e., 1 hour before or 2 hours after food. Swallow Uniprost 500 mg Tablet 60's as a whole with a glass of water; do not chew or break it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Uniprost 500 mg Tablet 60's

  • Diarrhoea
  • Low blood potassium
  • High blood pressure
  • Urinary tract infection
  • Oedema (fluid in legs or feet)

Drug Warnings

Do not take Uniprost 500 mg Tablet 60's if you are allergic to any of its components, if you have severe liver damage, or in combination with Ra-233 (used to treat prostate cancer). Inform your doctor if you have liver problems, high blood pressure, low blood potassium, heart failure, heart or blood vessel problems, irregular or rapid heartbeat, heart rhythm problems, shortness of breath, rapid weight gain, swelling in the legs, ankles, or feet, high blood sugar, bone problems, or if you have taken ketoconazole in the past for prostate cancer. Uniprost 500 mg Tablet 60's may cause libido (decreased sex drive), muscle weakness, decreased red blood cells, and/or muscle pain. Uniprost 500 mg Tablet 60's should not be given in combination with Ra-233 due to an increased risk of bone fracture or death.

Drug Interactions

Drug-Drug Interactions: Inform your doctor if you are taking drugs used to treat heart rhythm problems (quinidine, procainamide, amiodarone, sotalol), pain killer (methadone), antibiotic (moxifloxacin), herbal medicine (St. John’s wort) and antipsychotics. 

Drug-Food Interactions: Avoid taking Uniprost 500 mg Tablet 60's with food as it may cause side effects. Take Uniprost 500 mg Tablet 60's on an empty stomach, i.e., 1 hour before or 2 hours after food.

Drug-Disease Interactions: Inform your doctor if you have severe liver damage, low blood potassium, heart or blood vessel condition, or arrhythmia (heart rhythm problems).

Drug-Drug Interactions Checker List

  • QUINIDINE
  • PROCAINAMIDE
  • AMIODARONE
  • SOTALOL
  • METHADONE
  • MOXIFLOXACIN
  • ST JOHN'S WORT

Habit Forming

No

Diet & Lifestyle Advise

  • Eat a healthy diet and exercise regularly to maintain proper weight.
  • Avoid smoking and alcohol consumption.
  • Avoid fast, fried, processed meats, refined carbs, and added sugar.
  • Get optimal sleep; rest well.

Special Advise

  • Uniprost 500 mg Tablet 60's may affect the liver. Therefore your doctor may advise regular blood tests to check for any effects on the liver.
  • Tell your doctor if you experience darkening of the urine, yellowing of the skin or eyes, or severe vomiting or nausea, as these could be signs of liver problems.
  • Uniprost 500 mg Tablet 60's may cause low blood potassium. Stop taking Uniprost 500 mg Tablet 60's and consult a doctor immediately if you experience muscle twitches, muscle weakness, or palpitations (pounding heartbeat).
  • Use a condom or effective birth control method if you are having sex with pregnant women or women who can become pregnant.

Disease/Condition Glossary

Prostate cancer: Prostate cancer, also called prostatic carcinoma, is cancer in the prostate gland (a gland that produces seminal fluid). Symptoms include difficulty with urination, weak or interrupted flow of urine, trouble emptying the bladder completely, and pain or burning during urination.

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Alcohol

Consult your doctor

It is unknown if alcohol affects Uniprost 500 mg Tablet 60's. Please consult your doctor.

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Pregnancy

Unsafe

Uniprost 500 mg Tablet 60's is not for use in women.

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Breast Feeding

Not applicable

Uniprost 500 mg Tablet 60's is not for use in women.

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Driving

Safe if prescribed

Uniprost 500 mg Tablet 60's is not likely to affect your ability to drive or operate machinery.

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Liver

Caution

Do not take Uniprost 500 mg Tablet 60's if you have severe liver damage. Please consult your doctor if you have a liver impairment or any concerns.

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Kidney

Consult your doctor

Please consult your doctor if you have kidney impairment or any concerns.

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Children

Not applicable

Uniprost 500 mg Tablet 60's is not for use in children and adolescents.

Country of origin

India

Manufacturer/Marketer address

163, Reservoir Street, Basavanagudi, Bengaluru, Karnataka - 560004
Other Info - UNI0620

Author Details

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FAQs

Uniprost 500 mg Tablet 60's is used to treat Prostate cancer.
Uniprost 500 mg Tablet 60's works by stopping the body from making testosterone, thereby slowing the growth of prostate cancer.
Prednisolone/prednisone is prescribed along with Uniprost 500 mg Tablet 60's to lower the chances of getting high blood pressure, fluid retention (having too much water in the body), or low blood potassium levels.
Uniprost 500 mg Tablet 60's should not be given along with Ra-233 (a radioactive isotope used to treat prostate cancer) due to the increased risk of bone fracture or death. If you are prescribed to take Ra-233 following treatment with Uniprost 500 mg Tablet 60's and prednisolone/prednisone, you must wait five days before starting treatment with Ra-233.
No, Uniprost 500 mg Tablet 60's cannot cure prostate cancer. However, it is used to manage advanced or metastatic prostate cancer that works by inhibiting the production of testosterone, thereby preventing the growth and spread of cancer.
No, Uniprost 500 mg Tablet 60's is not a chemotherapy drug. It is a hormone therapy medication, which reduces testosterone levels to help manage prostate cancer.
Yes, Uniprost 500 mg Tablet 60's may affect the liver. Therefore, the doctor may advise regular blood tests to monitor its effects on the liver.
For patients taking Uniprost 500 mg Tablet 60's liver investigations are recommended. However, the frequency may differ for each individual and can be determined by the doctor based on your medical condition.
Uniprost 500 mg Tablet 60's can be taken orally on an empty stomach, either 1 hour before a meal or 2 hours after the meal. Swallow it as a whole with a glass of water. Do not chew or break it.
The side effects of Uniprost 500 mg Tablet 60's include oedema, urinary tract infection, high blood pressure, low blood potassium, and diarrhoea. Consult the doctor if any of these symptoms persist or worsen.

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