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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Abione-500Mg Tablet is used in combination with prednisone or prednisolone to treat prostate cancer in adult men that has spread to other body parts. It contains Abiraterone, which works by stopping the body from making testosterone, thereby slowing the growth of prostate cancer. It is not for use in women, children, and adolescents. In some cases, Abione-500Mg Tablet may cause common side effects such as diarrhoea, urinary tract infection, high blood pressure, low blood potassium, and oedema. If any of the side effects persist or worsen, consult your doctor.

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Whats That

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Synonym :

ABIRATERONE ACETATE

Composition :

ABIRATERONE-500MG

Manufacturer/Marketer :

Intas Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Abione-500Mg Tablet

Abione-500Mg Tablet belongs to the group of medicines called androgen biosynthesis inhibitors that is indicated in combination with prednisone or prednisolone to treat prostate cancer in adult men that have spread to other body parts.

Abione-500Mg Tablet contains ‘Abiraterone’ that works by stopping the body from making testosterone, thereby slowing the growth of prostate cancer.

In some cases, Abione-500Mg Tablet may cause common side effects such as diarrhoea, urinary tract infection, high blood pressure, low blood potassium, and oedema. If any of the side effects persist or worsen, consult your doctor.

Abione-500Mg Tablet is not for use in women, children, and adolescents. Abione-500Mg Tablet should not be given in combination with Ra-233 (a radioactive isotope used to treat prostate cancer) due to the increased risk of bone fracture or death. Inform your doctor about your health condition and medications to rule out any side effects/interactions.

Uses of Abione-500Mg Tablet

Treatment of Prostate cancer

Directions for Use

Take this medicine on an empty stomach, i.e., 1 hour before or 2 hours after food. Swallow Abione-500Mg Tablet as a whole with a glass of water; do not chew or break it.

Medicinal Benefits

Abione-500Mg Tablet belongs to the group of medicines called androgen biosynthesis inhibitors, indicated in combination with prednisone or prednisolone to treat prostate cancer in adult men that have spread to other body parts. Abione-500Mg Tablet contains ‘Abiraterone’ that works by stopping the body from making testosterone, thereby slowing the growth of prostate cancer. It is indicated in patients with metastatic castration-resistant prostate cancer (CRPC) who have received prior chemotherapy containing docetaxel and metastatic high-risk castration-sensitive prostate cancer (CSPC). Abione-500Mg Tablet is prescribed in the early stages of the disease, where it is still responding to hormone therapy. It is used with androgen deprivation therapy (a treatment that lowers testosterone).

How Abione-500Mg Tablet Works

Abione-500Mg Tablet contains ‘Abiraterone’ that works by stopping the body from making testosterone, thereby slowing the growth of prostate cancer.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Abione-500Mg Tablet

  • Diarrhoea
  • Low blood potassium
  • High blood pressure
  • Urinary tract infection
  • Oedema (fluid in legs or feet)

What if I have taken an overdose of Abione-500Mg Tablet

Please do not exceed the recommended dose, as it might cause an overdose. Signs and symptoms of an overdose of Abione-500Mg Tablet may include fast or irregular heartbeat, lightheadedness, dizziness, or fainting, shortness of breath or difficulty breathing, swelling of the feet, ankles, or lower legs, and unexplained weight gain. Seek immediate medical attention if you observe any symptoms or think you have taken too much. Do this even if there are no signs of discomfort or poisoning.

Drug Warnings

Do not take Abione-500Mg Tablet if you are allergic to any of its components, if you have severe liver damage, or in combination with Ra-233 (used to treat prostate cancer). Inform your doctor if you have liver problems, high blood pressure, low blood potassium, heart failure, heart or blood vessel problems, irregular or rapid heartbeat, heart rhythm problems, shortness of breath, rapid weight gain, swelling in the legs, ankles, or feet, high blood sugar, bone problems, or if you have taken ketoconazole in the past for prostate cancer. Abione-500Mg Tablet may cause libido (decreased sex drive), muscle weakness, decreased red blood cells, and/or muscle pain. Abione-500Mg Tablet should not be given in combination with Ra-233 due to an increased risk of bone fracture or death.

Drug-Drug Interactions

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AbirateroneSaquinavir
Critical
AbirateroneEliglustat
Critical

Drug-Drug Interactions

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AbirateroneSaquinavir
Critical
How does the drug interact with Abione-500Mg Tablet 60'S:
Taking Abione-500Mg Tablet 60'S with Saquinavir can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Taking Abione-500Mg Tablet 60'S and Saquinavir together is not recommended as it can result in an interaction; it can be taken if your doctor has advised it. However, contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss. Do not discontinue any medications without consulting a doctor.
AbirateroneEliglustat
Critical
How does the drug interact with Abione-500Mg Tablet 60'S:
Coadministration of Abione-500Mg Tablet 60'S with Eliglustat can increase the levels of Eliglustat in the body. This increases the risk or severity of side effects.

How to manage the interaction:
Taking Abione-500Mg Tablet 60'S with Eliglustat is not recommended as it can result in an interaction, it can be taken if your doctor has advised it. However, contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, slow heart rate, weak pulse, or heart palpitations. Do not discontinue any medications without consulting a doctor.
AbirateroneMesoridazine
Critical
How does the drug interact with Abione-500Mg Tablet 60'S:
Taking Abione-500Mg Tablet 60'S with Mesoridazine can increase the risk or severity of irregular heart rhythm.

How to manage the interaction:
Taking Abione-500Mg Tablet 60'S and Mesoridazine together is not recommended as it can result in an interaction. It can be taken if your doctor has advised it. However, contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat. Do not discontinue any medications without consulting a doctor.
AbirateroneZiprasidone
Critical
How does the drug interact with Abione-500Mg Tablet 60'S:
Taking Abione-500Mg Tablet 60'S with ziprasidone can increase the risk or severity of irregular heart rhythm.

How to manage the interaction:
Although there is an interaction between Abione-500Mg Tablet 60'S and ziprasidone, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience sudden dizziness, lightheadedness, fainting, or shortness of breath. Do not discontinue any medications without consulting a doctor.
AbirateroneThioridazine
Critical
How does the drug interact with Abione-500Mg Tablet 60'S:
Taking Abione-500Mg Tablet 60'S with Thioridazine can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Taking Abione-500Mg Tablet 60'S and Thioridazine together is not recommended and can result in an interaction; it can be taken if your doctor has advised it. However, contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, or a rapid heartbeat. Do not discontinue any medications without consulting a doctor.
AbirateroneHydrocodone
Severe
How does the drug interact with Abione-500Mg Tablet 60'S:
Coadministration of Abione-500Mg Tablet 60'S with Hydrocodone can increase the levels of Hydrocodone in the body. This increases the risk or severity of side effects like low blood pressure, and low respiratory rate.

How to manage the interaction:
Taking Abione-500Mg Tablet 60'S with Hydrocodone together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience drowsiness, dizziness, lightheadedness, difficulty concentrating, impairment in thinking and judgment, fainting, confusion, excessive drowsiness, slow heart rate, and shallow or difficult breathing, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
AbirateroneCeritinib
Severe
How does the drug interact with Abione-500Mg Tablet 60'S:
Taking Abione-500Mg Tablet 60'S with Ceritinib can increase the risk or severity of irregular heart rhythm.

How to manage the interaction:
Taking Abione-500Mg Tablet 60'S with Ceritinib together can result in an interaction, it can be taken if your doctor has advised it. However, contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss. Do not discontinue any medications without consulting a doctor.
AbirateroneVemurafenib
Severe
How does the drug interact with Abione-500Mg Tablet 60'S:
Taking Abione-500Mg Tablet 60'S with Vemurafenib can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Taking Abione-500Mg Tablet 60'S with Vemurafenib together can result in an interaction, it can be taken if your doctor has advised it. However, contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss. Do not discontinue any medications without consulting a doctor.
AbirateronePanobinostat
Severe
How does the drug interact with Abione-500Mg Tablet 60'S:
Using Panobinostat together with Abione-500Mg Tablet 60'S can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
There may be a possibility of interaction between Abione-500Mg Tablet 60'S and Panobinostat, but it can be taken if prescribed by a doctor. If you have any of these symptoms, it's important to contact a doctor right away: an irregular heart rhythm, a heart condition, congenital long qt syndrome, conduction abnormalities, severe or prolonged diarrhea, vomiting, complications, sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not stop using any medications without talking to a doctor.
AbirateroneLeflunomide
Severe
How does the drug interact with Abione-500Mg Tablet 60'S:
Coadministration of Abione-500Mg Tablet 60'S with leflunomide can increase the risk of liver problems.

How to manage the interaction:
Although there is an interaction between Abione-500Mg Tablet 60'S and leflunomide, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience ever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark-colored urine, light-colored stools, and/or yellowing of the skin or eyes. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat a healthy diet and exercise regularly to maintain proper weight.
  • Avoid smoking and alcohol consumption.
  • Avoid fast, fried, processed meats, refined carbs, and added sugar.
  • Get optimal sleep; rest well.

Habit Forming

No

Therapeutic Class

MISCELLANEOUS

Abione-500Mg Tablet Substitute

Substitutes safety advice
  • Samtica 500 mg Tablet 60's

    423.67per tablet
  • Abiratred Tablet 60's

    191.33per tablet
  • Alkeprost 500 mg Tablet 60's

    191.32per tablet
  • Mytera 500 mg Tablet 60's

    245.86per tablet
  • Abirapro 500Mg Tablet 60'S

    by AYUR

    410.67per tablet
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Alcohol

Consult your doctor

It is unknown if alcohol affects Abione-500Mg Tablet . Please consult your doctor.

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Pregnancy

Unsafe

Abione-500Mg Tablet is not for use in women.

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Breast Feeding

Not applicable

Abione-500Mg Tablet is not for use in women.

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Driving

Safe if prescribed

Abione-500Mg Tablet is not likely to affect your ability to drive or operate machinery.

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Liver

Caution

Do not take Abione-500Mg Tablet if you have severe liver damage. Please consult your doctor if you have a liver impairment or any concerns.

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Kidney

Consult your doctor

Please consult your doctor if you have kidney impairment or any concerns.

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Children

Not applicable

Abione-500Mg Tablet is not for use in children and adolescents.

FAQs

Abione-500Mg Tablet is used to treat Prostate cancer.
Abione-500Mg Tablet works by stopping the body from making testosterone, thereby slowing the growth of prostate cancer.
Prednisolone/prednisone is prescribed along with Abione-500Mg Tablet to lower the chances of getting high blood pressure, fluid retention (having too much water in the body), or low blood potassium levels.
Abione-500Mg Tablet should not be given along with Ra-233 (a radioactive isotope used to treat prostate cancer) due to the increased risk of bone fracture or death. If you are prescribed to take Ra-233 following treatment with Abione-500Mg Tablet and prednisolone/prednisone, you must wait five days before starting treatment with Ra-233.
No, Abione-500Mg Tablet cannot cure prostate cancer. However, it is used to manage advanced or metastatic prostate cancer that works by inhibiting the production of testosterone, thereby preventing the growth and spread of cancer.
No, Abione-500Mg Tablet is not a chemotherapy drug. It is a hormone therapy medication, which reduces testosterone levels to help manage prostate cancer.
Yes, Abione-500Mg Tablet may affect the liver. Therefore, the doctor may advise regular blood tests to monitor its effects on the liver.
For patients taking Abione-500Mg Tablet liver investigations are recommended. However, the frequency may differ for each individual and can be determined by the doctor based on your medical condition.
Abione-500Mg Tablet can be taken orally on an empty stomach, either 1 hour before a meal or 2 hours after the meal. Swallow it as a whole with a glass of water. Do not chew or break it.
The side effects of Abione-500Mg Tablet include oedema, urinary tract infection, high blood pressure, low blood potassium, and diarrhoea. Consult the doctor if any of these symptoms persist or worsen.

Country of origin

India

Manufacturer/Marketer address

Chinubhai Centre, Off. Nehru Bridge, Ashram Road, Ahmedabad - 380009. Gujarat. India.
Other Info - ABI0047

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