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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Nov 23, 2024 | 4:27 PM IST

Abirapro 500Mg Tablet is used in combination with prednisone or prednisolone to treat prostate cancer in adult men that has spread to other body parts. It contains Abiraterone, which works by stopping the body from making testosterone, thereby slowing the growth of prostate cancer. It is not for use in women, children, and adolescents. In some cases, Abirapro 500Mg Tablet may cause common side effects such as diarrhoea, urinary tract infection, high blood pressure, low blood potassium, and oedema. If any of the side effects persist or worsen, consult your doctor.

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Prescription drug

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Synonym

ABIRATERONE ACETATE

Manufacturer/Marketer

Glenmark Pharmaceuticals Ltd

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About Abirapro 500Mg Tablet

Abirapro 500Mg Tablet belongs to the group of medicines called androgen biosynthesis inhibitors that is indicated in combination with prednisone or prednisolone to treat prostate cancer in adult men that have spread to other body parts.

Abirapro 500Mg Tablet contains ‘Abiraterone’ that works by stopping the body from making testosterone, thereby slowing the growth of prostate cancer.

In some cases, Abirapro 500Mg Tablet may cause common side effects such as diarrhoea, urinary tract infection, high blood pressure, low blood potassium, and oedema. If any of the side effects persist or worsen, consult your doctor.

Abirapro 500Mg Tablet is not for use in women, children, and adolescents. Abirapro 500Mg Tablet should not be given in combination with Ra-233 (a radioactive isotope used to treat prostate cancer) due to the increased risk of bone fracture or death. Inform your doctor about your health condition and medications to rule out any side effects/interactions.

Uses of Abirapro 500Mg Tablet

Treatment of Prostate cancer

Medicinal Benefits

Abirapro 500Mg Tablet belongs to the group of medicines called androgen biosynthesis inhibitors, indicated in combination with prednisone or prednisolone to treat prostate cancer in adult men that have spread to other body parts. Abirapro 500Mg Tablet contains ‘Abiraterone’ that works by stopping the body from making testosterone, thereby slowing the growth of prostate cancer. It is indicated in patients with metastatic castration-resistant prostate cancer (CRPC) who have received prior chemotherapy containing docetaxel and metastatic high-risk castration-sensitive prostate cancer (CSPC). Abirapro 500Mg Tablet is prescribed in the early stages of the disease, where it is still responding to hormone therapy. It is used with androgen deprivation therapy (a treatment that lowers testosterone).

Directions for Use

Take this medicine on an empty stomach, i.e., 1 hour before or 2 hours after food. Swallow Abirapro 500Mg Tablet as a whole with a glass of water; do not chew or break it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Abirapro 500Mg Tablet

  • Diarrhoea
  • Low blood potassium
  • High blood pressure
  • Urinary tract infection
  • Oedema (fluid in legs or feet)

Drug Warnings

Do not take Abirapro 500Mg Tablet if you are allergic to any of its components, if you have severe liver damage, or in combination with Ra-233 (used to treat prostate cancer). Inform your doctor if you have liver problems, high blood pressure, low blood potassium, heart failure, heart or blood vessel problems, irregular or rapid heartbeat, heart rhythm problems, shortness of breath, rapid weight gain, swelling in the legs, ankles, or feet, high blood sugar, bone problems, or if you have taken ketoconazole in the past for prostate cancer. Abirapro 500Mg Tablet may cause libido (decreased sex drive), muscle weakness, decreased red blood cells, and/or muscle pain. Abirapro 500Mg Tablet should not be given in combination with Ra-233 due to an increased risk of bone fracture or death.

Drug Interactions

Drug-Drug Interactions: Inform your doctor if you are taking drugs used to treat heart rhythm problems (quinidine, procainamide, amiodarone, sotalol), pain killer (methadone), antibiotic (moxifloxacin), herbal medicine (St. John’s wort) and antipsychotics. 

Drug-Food Interactions: Avoid taking Abirapro 500Mg Tablet with food as it may cause side effects. Take Abirapro 500Mg Tablet on an empty stomach, i.e., 1 hour before or 2 hours after food.

Drug-Disease Interactions: Inform your doctor if you have severe liver damage, low blood potassium, heart or blood vessel condition, or arrhythmia (heart rhythm problems).

Drug-Drug Interactions Checker List

  • QUINIDINE
  • PROCAINAMIDE
  • AMIODARONE
  • SOTALOL
  • METHADONE
  • MOXIFLOXACIN
  • ST JOHN'S WORT

Habit Forming

No

Diet & Lifestyle Advise

  • Eat a healthy diet and exercise regularly to maintain proper weight.
  • Avoid smoking and alcohol consumption.
  • Avoid fast, fried, processed meats, refined carbs, and added sugar.
  • Get optimal sleep; rest well.

Special Advise

  • Abirapro 500Mg Tablet may affect the liver. Therefore your doctor may advise regular blood tests to check for any effects on the liver.
  • Tell your doctor if you experience darkening of the urine, yellowing of the skin or eyes, or severe vomiting or nausea, as these could be signs of liver problems.
  • Abirapro 500Mg Tablet may cause low blood potassium. Stop taking Abirapro 500Mg Tablet and consult a doctor immediately if you experience muscle twitches, muscle weakness, or palpitations (pounding heartbeat).
  • Use a condom or effective birth control method if you are having sex with pregnant women or women who can become pregnant.

Disease/Condition Glossary

Prostate cancer: Prostate cancer, also called prostatic carcinoma, is cancer in the prostate gland (a gland that produces seminal fluid). Symptoms include difficulty with urination, weak or interrupted flow of urine, trouble emptying the bladder completely, and pain or burning during urination.

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Alcohol

Consult your doctor

It is unknown if alcohol affects Abirapro 500Mg Tablet . Please consult your doctor.

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Pregnancy

Unsafe

Abirapro 500Mg Tablet is not for use in women.

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Breast Feeding

Not applicable

Abirapro 500Mg Tablet is not for use in women.

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Driving

Safe if prescribed

Abirapro 500Mg Tablet is not likely to affect your ability to drive or operate machinery.

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Liver

Caution

Do not take Abirapro 500Mg Tablet if you have severe liver damage. Please consult your doctor if you have a liver impairment or any concerns.

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Kidney

Consult your doctor

Please consult your doctor if you have kidney impairment or any concerns.

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Children

Not applicable

Abirapro 500Mg Tablet is not for use in children and adolescents.

Country of origin

India

Manufacturer/Marketer address

Glenmark Pharmaceuticals Limited, B/2, Mahalaxmi Chambers, 22, Bhulabhai Desai Road, Mumbai – 400 026.
Other Info - ABI0056

Author Details

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FAQs

Abirapro 500Mg Tablet is used to treat Prostate cancer.
Abirapro 500Mg Tablet works by stopping the body from making testosterone, thereby slowing the growth of prostate cancer.
Prednisolone/prednisone is prescribed along with Abirapro 500Mg Tablet to lower the chances of getting high blood pressure, fluid retention (having too much water in the body), or low blood potassium levels.
Abirapro 500Mg Tablet should not be given along with Ra-233 (a radioactive isotope used to treat prostate cancer) due to the increased risk of bone fracture or death. If you are prescribed to take Ra-233 following treatment with Abirapro 500Mg Tablet and prednisolone/prednisone, you must wait five days before starting treatment with Ra-233.
No, Abirapro 500Mg Tablet cannot cure prostate cancer. However, it is used to manage advanced or metastatic prostate cancer that works by inhibiting the production of testosterone, thereby preventing the growth and spread of cancer.
No, Abirapro 500Mg Tablet is not a chemotherapy drug. It is a hormone therapy medication, which reduces testosterone levels to help manage prostate cancer.
Yes, Abirapro 500Mg Tablet may affect the liver. Therefore, the doctor may advise regular blood tests to monitor its effects on the liver.
For patients taking Abirapro 500Mg Tablet liver investigations are recommended. However, the frequency may differ for each individual and can be determined by the doctor based on your medical condition.
Abirapro 500Mg Tablet can be taken orally on an empty stomach, either 1 hour before a meal or 2 hours after the meal. Swallow it as a whole with a glass of water. Do not chew or break it.
The side effects of Abirapro 500Mg Tablet include oedema, urinary tract infection, high blood pressure, low blood potassium, and diarrhoea. Consult the doctor if any of these symptoms persist or worsen.

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