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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Oncyclo 50mg Capsule is used to prevent organ transplant rejection. It is also used to treat inflammation and pain associated with psoriasis and rheumatoid arthritis. This medicine contains cyclosporine, which works by suppressing the immune system. It also helps reduce rapid skin cell growth, pain, and inflammation. It may sometimes cause common side effects such as headaches, vomiting, nausea, high blood pressure, increased hair growth, loss of appetite, and diarrhoea. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Whats That

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Synonym :

CYCLOSPORIN

Composition :

CYCLOSPORINE-50MG

Manufacturer/Marketer :

Bharat Serums and Vaccines Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

About Oncyclo 50mg Capsule

Oncyclo 50mg Capsule belongs to a group of medications called 'immunosuppressants,' primarily used to prevent organ transplant rejection after liver, kidney, pancreas, lungs, heart, skin, and bone marrow transplants. It is also used to treat symptoms associated with psoriasis and rheumatoid arthritis. Organ transplant rejection occurs when the immune system attacks a transplanted organ. Psoriasis is a long-lasting, inflammatory skin illness.  Rheumatoid arthritis is an autoimmune disease, where the body's immune system attacks its own tissue, leading to joint pain and damage.

Oncyclo 50mg Capsule contains 'cyclosporine,' which works by suppressing the immune system, thereby stopping your body from rejecting a new organ. It also reduces rapid skin cell growth and the production of interleukins (molecules involved in inflammation), which are needed for T cells to activate and attack the body. Additionally, it also reduces pain and inflammation in the joints and slows down the joint damage caused by an overactive immune system.

You are advised to take Oncyclo 50mg Capsule for as long as your doctor has prescribed it, depending on your medical condition. You may experience headaches, vomiting, nausea, high blood pressure, increased hair growth, loss of appetite (feeling unwell and upset stomach), kidney disease, and diarrhoea. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

To treat your condition effectually, continue taking Oncyclo 50mg Capsule for as long as your doctor has prescribed. To avoid recurring symptoms, do not stop it midway. Before taking Oncyclo 50mg Capsule, inform your doctor if you have any allergies, kidney disease, uncontrolled high blood pressure, or any type of cancer. Oncyclo 50mg Capsule should not be taken by breastfeeding mothers as it passes into breast milk. Inform your doctor about your health condition and any medications you are taking to help rule out any potential unpleasant side effects.

Uses of Oncyclo 50mg Capsule

Treatment of Organ Transplant Rejection: Oncyclo 50mg Capsule is used in the prevention of organ transplant rejection after liver, kidney, pancreas, lungs, heart, skin, and bone marrow transplants. It helps prevent organ rejection by suppressing the immune system.
Treatment of Psoriasis: Oncyclo 50mg Capsule is used in the treatment of psoriasis. It helps reduce rapid skin cell growth and inflammation caused by psoriasis.
Treatment of Rheumatoid Arthritis: Oncyclo 50mg Capsule is used in the treatment of rheumatoid arthritis. It helps reduce pain and inflammation in the joints and slows down joint damage.

Directions for Use

  • Oncyclo 50mg Capsule ideally should be given 12 hours apart. It should be taken with water and swallowed whole.
  • Grapefruit and grapefruit juice should be avoided as they can raise ciclosporin levels in the blood. 

Medicinal Benefits

Oncyclo 50mg Capsule is an immunosuppressant medication used to prevent organ transplant rejection. It contains cyclosporine, which suppresses the immune system and prevents your body from rejecting a new organ. It helps reduce rapid skin cell growth and inflammation caused by psoriasis. Additionally, it helps reduce pain and inflammation in the joints and slows down joint damage caused by an overactive immune system in people with rheumatoid arthritis.

How Oncyclo 50mg Capsule Works

Oncyclo 50mg Capsule contains 'cyclosporine,' which works by suppressing the immune system, thereby stopping your body from rejecting a new organ. It also reduces rapid skin cell growth and the production of interleukins (molecules involved in inflammation), which are needed for T cells to activate and attack the body. Additionally, it also reduces pain and inflammation in the joints and slows down the joint damage caused by an overactive immune system.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Oncyclo 50mg Capsule

  • Headache
  • Vomiting
  • Nausea
  • High blood pressure
  • Increased growth of hair
  • Loss of appetite (feeling unwell and having an upset stomach)
  • Kidney disease
  • Diarrhoea

What if I have taken an overdose of Oncyclo 50mg Capsule

Take Oncyclo 50mg Capsule only as prescribed by the physician. Do not exceed the recommended dose, as it might cause an overdose. Symptoms of overdose may include headache, drowsiness, vomiting, increased heart rate, liver and kidney toxicity. If you experience these symptoms or suspect you have taken an overdose, seek immediate medical attention.

Drug Warnings

Do not take Oncyclo 50mg Capsule if you are allergic to any immunosuppressant medicines or Cyclosporine. Let your doctor know if you have liver or kidney problems, high blood pressure, low magnesium levels, or high potassium levels. Your Oncyclo 50mg Capsule may make you more susceptible to infections. Consult your doctor if you develop any signs of severe conditions, such as fever, sore throat, breathlessness, jaundice, unexplained bleeding, or bruising. Before taking Oncyclo 50mg Capsule inform your doctor if you have any type of cancer. Oncyclo 50mg Capsule should not be taken by breastfeeding mothers as it passes into breast milk. Inform your doctor about your health condition and any medications you are taking to help rule out any potential unpleasant side effects.

Diet & Lifestyle Advise

  • Physical activity helps strengthen muscles and relieve joint stiffness. Gentle activities, such as 20-30 minutes of walking or swimming, would be helpful.
  • Practising yoga may also help improve joint flexibility and manage pain.
  • Maintain a healthy weight by engaging in regular low-impact exercises and eating a balanced diet.
  • Get adequate sleep, as rest can help reduce inflammation and swelling.
  • Follow heat or cold therapy by applying a cold or hot compress to the joints for 15-20 minutes regularly.
  • De-stress yourself by meditating, reading books, taking a warm bubble bath, or listening to soothing music.
  • Acupuncture, massage, and physical therapy may also be helpful.
  • Eat foods rich in antioxidants, such as berries, spinach, kidney beans, and dark chocolate.
  • Foods containing flavonoids can help reduce inflammation. These include soy, berries, broccoli, grapes, and green tea.
  • Avoid smoking and alcohol consumption.

Habit Forming

No

Therapeutic Class

IMMUNOSUPPRESSANTS

Oncyclo 50mg Capsule Substitute

Substitutes safety advice
  • Sandimmun Neoral 50 mg Capsule 5's

    by Others

    50.86per tablet
  • Psorid 50 Capsule 5's

    by Others

    57.80per tablet
  • Iminoral 50 Capsule 5's

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  • Panimun Bioral 50 mg Capsule 6's

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    50.60per tablet
  • Arpimune ME 50 Tablet 5's

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Alcohol

Caution

You are recommended to avoid alcohol consumption while taking Oncyclo 50mg Capsule. It could lead to increased dizziness and drowsiness.

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Pregnancy

Caution

It is not known whether Oncyclo 50mg Capsule will harm an unborn baby. Inform your doctor if you are pregnant or plan to become pregnant.

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Breast Feeding

Unsafe

It is not recommended to take Oncyclo 50mg Capsule while you are breastfeeding. Oncyclo 50mg Capsule passes into breast milk.

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Driving

Caution

Drive or operate machinery only if you are alert.

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Liver

Caution

Take Oncyclo 50mg Capsule only if prescribed by the doctor, especially if you are dealing with Liver diseases/conditions, as your doctor may adjust the dose as required.

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Kidney

Caution

Please consult your doctor if you have kidney impairment before taking Oncyclo 50mg Capsule.

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Children

Unsafe

Oncyclo 50mg Capsule should not be given to children, as the efficacy and safety have not been established.

FAQs

Oncyclo 50mg Capsule belongs to a group of medications called 'immunosuppressants,' primarily used to prevent organ transplant rejection after liver, kidney, pancreas, lungs, heart, skin, and bone marrow transplants. It is also used to treat symptoms associated with psoriasis and rheumatoid arthritis.

Oncyclo 50mg Capsule acts as an immunosuppressant, which helps reduce pain and inflammation in the joints and prevent joint stiffness, thereby relieving rheumatoid arthritis.

If you miss a dose of Oncyclo 50mg Capsule, take it as soon as you remember. However, if it is almost time for the next dose, skip the missed dose and take the scheduled dose. Do not take a double dose to make up for a missed one.

Diarrhoea might be a side-effect of Oncyclo 50mg Capsule. Drink lots of fluids and eat food rich in fibre if you experience diarrhoea. If you find blood in your stools (tarry stools) or experience excess diarrhoea consult your doctor. Do not take anti-diarrheal medicine on your own.

Yes, using Oncyclo 50mg Capsule may cause abnormal hair growth, although it does not affect everybody. Consult your doctor if you have any concerns.

Oncyclo 50mg Capsule is known to decrease the immune system. As a result, it increases your risk of developing certain types of cancer, especially skin cancer. You should reduce your contact with sunlight and UV light by wearing suitable protective clothing. Sunscreen should be used regularly.

No, Oncyclo 50mg Capsule is not a steroid. It is an immunosuppressant.

Yes, cyclosporine can cause weight gain. However, this is not a common side effect, and the amount of weight gain varies from person to person.

Yes, fatigue is a common side effect of cyclosporine. Many people who take cyclosporine report feeling tired or fatigued.

Oncyclo 50mg Capsule is an immunosuppressant medication, meaning it weakens your immune system. This can make you more susceptible to infections and other health problems. Your doctor will likely order regular blood tests to monitor your health and ensure the medication is working effectively.

Oncyclo 50mg Capsule has not been definitively linked to causing cancer. However, discussing any concerns you may have with your doctor is essential. They can provide personalized information about your health situation and why you take cyclosporine.

Common side effects of Oncyclo 50mg Capsule may include headaches, vomiting, nausea, high blood pressure, increased hair growth, loss of appetite (feeling unwell and upset stomach), kidney disease, and diarrhoea. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Oncyclo 50mg Capsule ideally should be given 12 hours apart. The capsules should be taken with water and swallowed whole. Grapefruit and grapefruit juice should be avoided, as they can increase ciclosporin levels in the blood.

The duration of Oncyclo 50mg Capsule treatment varies depending on the underlying condition and individual response.

Always consult with your doctor or pharmacist before starting any new medications or supplements while taking Oncyclo 50mg Capsule. They can help you identify potential interactions and recommend safe alternatives if necessary.

Yes, you can travel while taking cyclosporine. However, it's essential to plan and take necessary precautions. Ensure you have a sufficient supply of your medication, and be aware of any potential customs regulations or travel restrictions.

Generally, moderate exercise is safe while taking Oncyclo 50mg Capsule. However, listening to your body and avoiding overexertion is essential, especially if you have any underlying health conditions.

Excessive alcohol consumption can increase the risk of side effects and interact with cyclosporine. It's best to limit alcohol intake or avoid it altogether while taking this medication.

Your doctor will determine the frequency of your blood tests based on your situation. However, regular monitoring is essential to ensure that cyclosporine works effectively and detects potential side effects.

If you miss a dose of Oncyclo 50mg Capsule, take it as soon as you remember. However, if it's almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose.

Some people may experience mood changes or anxiety while taking Oncyclo 50mg Capsule. If you notice any changes in your mental health, it's important to talk to your doctor.

Oncyclo 50mg Capsule occasionally causes blurred vision or eye irritation. If you experience any vision problems, contact your doctor.

Before using this medication, you should inform your doctor about your medical history, including any ongoing medicines, to avoid potential interactions and minimize side effects.

Taking more than the recommended dosage does not provide additional benefit and can increase the risk of adverse effects.

Oncyclo 50mg Capsule contains cyclosporine, an immunosuppressant.

Oncyclo 50mg Capsule should not be given to children, as the efficacy and safety have not been established.

Country of origin

India
Other Info - ON73031

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