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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Cyclostim 50 Softgel Capsule is used to reduce the pain and inflammation in rheumatoid arthritis. It is also used to treat severe psoriasis and prevent organ rejection. This medicine contains cyclosporine which works by reducing the function of inflammation-causing cells, thereby it helps treat rheumatoid arthritis and psoriasis. It helps prevent organ rejection by suppressing the immune system.
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Whats That

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Synonym :

CYCLOSPORIN

Composition :

CICLOSPORIN-50MG

Manufacturer/Marketer :

Zydus Cadila

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

Jan-27

About Cyclostim 50 Softgel Capsule

Cyclostim 50 Softgel Capsule is an 'immunosuppressant' that helps to reduce the pain/inflammation in rheumatoid arthritis conditions and is also used to treat severe psoriasis. Besides this, it also prevents organ rejection after a kidney, heart, or liver transplant. Rheumatoid arthritis is an autoimmune disease (the body's immune system attacks its tissue) that leads to joint pain and damage. Psoriasis is a long-lasting, inflammatory skin illness. 

Cyclostim 50 Softgel Capsule contains 'cyclosporine' that works by reducing the function of the cells, causing inflammation, especially in the joint tissues, thereby decreasing pain and inflammation and slowing down the joint damage and disease progression over time. Besides this, after an organ transplant, your body will try to attack the new organ as it sees it as foreign. Cyclostim 50 Softgel Capsule helps stop your body from rejecting a new organ by suppressing your immune system. 

You are advised to take Cyclostim 50 Softgel Capsule for as long as your doctor has prescribed it for you, depending on your medical conditions. You may experience headaches, vomiting, nausea, high blood pressure, increased growth of hair, loss of appetite (feeling unwell and upset stomach), kidney disease, and diarrhoea. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

To treat your condition effectually, continue taking Cyclostim 50 Softgel Capsule for as long as your doctor has prescribed. To avoid recurring symptoms, do not stop it midway. Before taking Cyclostim 50 Softgel Capsule inform your doctor if you have any allergies, kidney disease, uncontrolled high blood pressure, and any type of cancer. Cyclostim 50 Softgel Capsule should not be taken by breastfeeding mothers as it passes into breast milk. Inform your doctor about your health condition and medicines to rule out any unpleasant side effects.

Uses of Cyclostim 50 Softgel Capsule

Treatment of Rheumatoid arthritis, Immunosuppressant therapy after organ (liver, kidney, and heart) transplant, and psoriasis (a skin disease that causes itchy and dry patches).

Directions for Use

Tablet/Capsule: Swallow it as a whole with water; do not crush, break or chew it.Solution/Syrup/Suspension/Drops: Shake the bottle well before use. Take the prescribed dose by mouth using the measuring cup/dosing syringe/dropper provided by the pack.

Medicinal Benefits

Cyclostim 50 Softgel Capsule belongs to the class of medicine called 'immunosuppressant' that helps to reduce the pain/inflammation in rheumatoid arthritis conditions and is also used to treat severe psoriasis. Besides this, it also prevents organ rejection after a kidney, heart, or liver transplant. Cyclostim 50 Softgel Capsule contains 'cyclosporine' that works by reducing the function of the cells, causing inflammation, especially in the joint tissues, thereby decreasing pain and inflammation and slowing down the joint damage and disease progression over time. Besides this, after an organ transplant, your body will try to attack the new organ as it sees it as foreign. Cyclostim 50 Softgel Capsule helps stop your body from rejecting a new organ by suppressing your immune system. 

How Cyclostim 50 Softgel Capsule Works

Cyclostim 50 Softgel Capsule contains 'cyclosporine' that works by reducing the function of the cells, causing inflammation, especially in the joint tissues, thereby decreasing pain and inflammation and slowing down the joint damage and disease progression over time. Besides this, after an organ transplant, your body will try to attack the new organ as it sees it as foreign. Cyclostim 50 Softgel Capsule helps stop your body from rejecting a new organ by suppressing your immune system.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Cyclostim 50 Softgel Capsule

  • Headache
  • Vomiting
  • Nausea
  • High blood pressure
  • Increased growth of hair
  • Loss of appetite (feeling unwell and having an upset stomach)
  • Kidney disease
  • Diarrhoea

What if I have taken an overdose of Cyclostim 50 Softgel Capsule

Take Cyclostim 50 Softgel Capsule only as prescribed by the physician. Do not exceed the recommended dose, as it might cause an overdose. Symptoms of overdose may include headache, drowsiness, vomiting, increased heart rate, liver and kidney toxicity. If you experience these symptoms or suspect you have taken an overdose, seek immediate medical attention.

Drug Warnings

Do not take Cyclostim 50 Softgel Capsule if you are allergic to any immunosuppressant medicines or Cyclosporine. Let your doctor know if you have liver or kidney problems, high blood pressure, low levels of magnesium, and high levels of potassium. Cyclostim 50 Softgel Capsule may make you more susceptible to infections; consult your doctor if you develop any signs of severe conditions such as fever, sore throat, breathlessness, jaundice, unexplained bleeding, or bruising. Before taking Cyclostim 50 Softgel Capsule inform your doctor if you have any type of cancer. Cyclostim 50 Softgel Capsule should not be taken by breastfeeding mothers as it passes into breast milk. Inform your doctor about your health condition and medicines to rule out any unpleasant side effects.

Drug-Drug Interactions

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CiclosporinSimvastatin
Critical
CiclosporinBosentan
Critical

Drug-Drug Interactions

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CiclosporinSimvastatin
Critical
How does the drug interact with Cyclostim 50 Softgel Capsule 6's:
Combining Cyclostim 50 Softgel Capsule 6's and Simvastatin can increase the blood levels and effects of Simvastatin. This can increase the risk of side effects such as liver damage and rhabdomyolysis(involves the breakdown of skeletal muscle tissue).

How to manage the interaction:
Taking Cyclostim 50 Softgel Capsule 6's and Simvastatin together is not recommended as it can lead to an interaction, but it can be taken if advised by your doctor. However, if you experience any symptoms like muscle pain, tenderness, or weakness, fever or dark colored urine, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of hunger, weakness, nausea, vomiting, and yellowing of the skin or eyes, contact the doctor immediately. Do not discontinue any medications without consulting your doctor.
CiclosporinBosentan
Critical
How does the drug interact with Cyclostim 50 Softgel Capsule 6's:
When Bosentan is taken with Cyclosporine, it may increase the risk of side effects.

How to manage the interaction:
Taking Cyclostim 50 Softgel Capsule 6's with Bosentan is not recommended, but it can be taken if prescribed by the doctor. However, if you experience any symptoms like severe headache, nausea, or an increased heart rate, consult the doctor immediately. Do not stop using any medications without talking to a doctor.
CiclosporinBaricitinib
Critical
How does the drug interact with Cyclostim 50 Softgel Capsule 6's:
Co-administration of Baricitinib with Cyclosporine can increase the risk of infections as well as some cancers.

How to manage the interaction:
Taking Cyclostim 50 Softgel Capsule 6's with Baricitinib is not recommended as it can cause an interaction, but it can be taken together if prescribed by a doctor. However, if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning sensation when you urinate, consult a doctor. Do not stop using any medications without a doctor's advice.
CiclosporinCidofovir
Critical
How does the drug interact with Cyclostim 50 Softgel Capsule 6's:
Taking cyclosporine with cidofovir can increase the risk of kidney problems.

How to manage the interaction:
Taking Cyclostim 50 Softgel Capsule 6's with Cidofovir is not recommended, but can be taken be together if prescribed by a doctor. However, if you experience nausea, vomiting, loss of hunger, increased or decreased urination, sudden weight gain or weight loss, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm, contact the doctor immediately. Do not discontinue any medications without consulting a doctor
CiclosporinPitavastatin
Critical
How does the drug interact with Cyclostim 50 Softgel Capsule 6's:
Coadministration of pitavastatin with Cyclostim 50 Softgel Capsule 6's may significantly increase the blood levels of pitavastatin which can increase the risk of side effects such as liver problems and rhabdomyolysis(involves the breakdown of skeletal muscle tissue).

How to manage the interaction:
Taking Pitavastatin with Cyclostim 50 Softgel Capsule 6's is not recommended, as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience symptoms like unexpected bruising or bleeding, skin rash, itching, tiredness, nausea, vomiting, yellowing of the skin or eyes, unexplained muscular pain, tenderness, or weakness, fever, dark urine, chills, joint pain, or swelling, consult a doctor. Do not discontinue any medications without a doctor's advice.
CiclosporinFoscarnet
Severe
How does the drug interact with Cyclostim 50 Softgel Capsule 6's:
Co-administration of foscarnet with Cyclostim 50 Softgel Capsule 6's may increases the risk of kidney problems.

How to manage the interaction:
Although there is a possible interaction between foscarnet and Cyclostim 50 Softgel Capsule 6's, they can be taken together if your doctor has prescribed them. However, if you experience nausea, vomiting, a decrease in hunger, increased or decreased urine, weight gain or loss that occurs suddenly, fluid retention, swelling, difficulty breathing, muscle pain, fatigue, weakness, dizziness, confusion, and irregular heartbeat, consult a doctor. Do not discontinue any medications without a doctor's advice.
CiclosporinInfliximab
Severe
How does the drug interact with Cyclostim 50 Softgel Capsule 6's:
When infliximab is taken with cyclosporine, it can increase the risk of infections.

How to manage the interaction:
Although taking infliximab and Cyclostim 50 Softgel Capsule 6's together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, contact a doctor immediately if you experience any symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without a doctor's advice.
CiclosporinColchicine
Severe
How does the drug interact with Cyclostim 50 Softgel Capsule 6's:
Co-administration of colchicine with Cyclostim 50 Softgel Capsule 6's may increases the blood levels and effects of both medications.

How to manage the interaction:
Although there is a possible interaction between colchicine and Cyclostim 50 Softgel Capsule 6's, you can take these medicines together if prescribed by your doctor. However, contact a doctor immediately if you experience any symptoms such as abdominal pain, diarrhoea, fever, muscle pain, weakness, and numbness or tingling in your hands and feet. Do not discontinue any medications without consulting a doctor.
CiclosporinTofacitinib
Severe
How does the drug interact with Cyclostim 50 Softgel Capsule 6's:
Co-administration of tofacitinib with cyclosporine may increase the risk of serious infections.

How to manage the interaction:
Although there is a possible interaction, tofacitinib can be taken with Cyclostim 50 Softgel Capsule 6's if prescribed by the doctor. Consult the prescriber if you experience side effects such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, red or inflamed skin, body sores, and pain or burning during urination. Do not discontinue the medication without a doctor's advice.
CiclosporinEverolimus
Severe
How does the drug interact with Cyclostim 50 Softgel Capsule 6's:
Taking everolimus with cyclosporine may significantly increases the blood levels of everolimus.

How to manage the interaction:
Although taking everolimus and Cyclostim 50 Softgel Capsule 6's together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience any unusual symptoms contact a doctor immediately. In case you experience any side effects like persistent cough, fever, chills, mouth ulcers, paleness of skin, or unusual bleeding or bruising, or blood in stools or urine, consult a doctor. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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CICLOSPORIN-50MGGrapefruit and Grapefruit Juice
Moderate

Drug-Food Interactions

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CICLOSPORIN-50MGGrapefruit and Grapefruit Juice
Moderate
Common Foods to Avoid:
Grapefruit Juice, Grapefruit

How to manage the interaction:
Consuming grapefruit and grapefruit juice while taking Cyclostim 50 Softgel Capsule 6's can increase the effects of Cyclostim 50 Softgel Capsule 6's. Avoid consuming grapefruit and grapefruit juice while taking Cyclostim 50 Softgel Capsule 6's.

Diet & Lifestyle Advise

  • Physical activity helps strengthen muscles and relieves joint stiffness. Gentle activities like 20-30 minutes of walking or swimming would be helpful.

  • Performing yoga may also help in improving joint flexibility and pain management.

  • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.

  • Get adequate sleep, as resting the muscles can help reduce inflammation and swelling.

  • Follow heat or cold therapy, and apply a cold or hot compress on the joints for 15-20 minutes regularly.

  • De-stress yourself by meditating, reading books, taking a warm bubble bath, or listening to soothing music.

  • Acupuncture, massage, and physical therapy may also be helpful.

  • Eat food rich in antioxidants such as berries, spinach, kidney beans, dark chocolate, etc.

  • Foods containing flavonoids help in reducing inflammation. These include soy, berries, broccoli, grapes, and green tea.

  • Avoid smoking and alcohol consumption.

Habit Forming

No

Therapeutic Class

IMMUNOSUPPRESSANTS

Cyclostim 50 Softgel Capsule Substitute

Substitutes safety advice
  • Grafotas-50 Capsule 5's

    by Others

    52.02per tablet
  • Zymmune 50 Capsule 6's

    by Others

    50.90per tablet
  • Psoranext 50mg Capsule 6's

    by Others

    37.35per tablet
  • Oncyclo 50mg Capsule

    by Others

    46.44per tablet
  • Imusporin 50mg Capsule

    by Others

    43.20per tablet
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Alcohol

Caution

You are recommended to avoid alcohol consumption while taking Cyclostim 50 Softgel Capsule. It could lead to increased dizziness and drowsiness.

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Pregnancy

Caution

It is not known whether Cyclostim 50 Softgel Capsule will harm an unborn baby. Inform your doctor if you are pregnant or plan to become pregnant.

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Breast Feeding

Unsafe

It is not recommended to take Cyclostim 50 Softgel Capsule while you are breastfeeding. Cyclostim 50 Softgel Capsule passes into breast milk.

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Driving

Caution

Drive or operate machinery only if you are alert.

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Liver

Caution

Take Cyclostim 50 Softgel Capsule only if prescribed by the doctor, especially if you are dealing with Liver diseases/conditions, as your doctor may adjust the dose as required.

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Kidney

Caution

Please consult your doctor if you have kidney impairment before taking Cyclostim 50 Softgel Capsule.

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Children

Unsafe

Cyclostim 50 Softgel Capsule should not be given to children, as the efficacy and safety have not been established.

FAQs

Cyclostim 50 Softgel Capsule is used to reduce the pain/inflammation in rheumatoid arthritis conditions and is also used to treat severe psoriasis. It also prevents organ rejection after a kidney, heart, or liver transplant.
Cyclostim 50 Softgel Capsule acts as an immunosuppressant, which helps reduce inflammation and prevent joint stiffness, thereby relieving rheumatoid arthritis.
If you miss a dose of Cyclostim 50 Softgel Capsule, take it as soon as you remember. However, if it is almost time for the next dose, skip the missed dose and take the scheduled dose. Do not take a double dose to make up for a missed one.
Diarrhoea might be a side-effect of Cyclostim 50 Softgel Capsule. Drink lots of fluids and eat food rich in fibre if you experience diarrhoea. If you find blood in your stools (tarry stools) or experience excess diarrhoea consult your doctor. Do not take anti-diarrheal medicine on your own.
Yes, using Cyclostim 50 Softgel Capsule may cause abnormal hair growth, although it does not affect everybody. Consult your doctor if you have any concerns.
Cyclostim 50 Softgel Capsule is known to decrease the immune system. As a result, it increases your risk of developing cancers, especially of the skin. You should reduce your contact with sunlight and UV light by wearing suitable protective clothing. Sunscreen should be used regularly.
No, Cyclostim 50 Softgel Capsule is not a steroid. It is an immunosuppressant.
Yes, cyclosporine can cause weight gain. However, this is not a common side effect, and the amount of weight gain varies from person to person.
Yes, fatigue is a common side effect of cyclosporine. Many people who take cyclosporine report feeling tired or fatigued.
Cyclostim 50 Softgel Capsule is an immunosuppressant medication, meaning it weakens your immune system. This can make you more susceptible to infections and other health problems. Your doctor will likely order regular blood tests to monitor your health and ensure the medication is working effectively.
Cyclostim 50 Softgel Capsule has not been definitively linked to causing cancer. However, discussing any concerns you may have with your doctor is essential. They can provide personalized information about your health situation and why you take cyclosporine.
Common side effects of Cyclostim 50 Softgel Capsule may include headaches, vomiting, nausea, high blood pressure, increased hair growth, loss of appetite (feeling unwell and upset stomach), kidney disease, and diarrhoea. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.
Cyclostim 50 Softgel Capsule should always be taken as prescribed by your doctor. The dosage and frequency will depend on your specific condition and other factors.
The duration of Cyclostim 50 Softgel Capsule treatment varies depending on the underlying condition and individual response.
Always consult with your doctor or pharmacist before starting any new medications or supplements while taking Cyclostim 50 Softgel Capsule. They can help you identify potential interactions and recommend safe alternatives if necessary.
Yes, you can travel while taking cyclosporine. However, it's important to plan ahead and take necessary precautions. Ensure you have a sufficient supply of your medication and consider any potential customs regulations or travel restrictions.
Generally, moderate exercise is safe while taking Cyclostim 50 Softgel Capsule. However, listening to your body and avoiding overexertion is essential, especially if you have any underlying health conditions.
Excessive alcohol consumption can increase the risk of side effects and interact with cyclosporine. It's best to limit alcohol intake or avoid it altogether while taking this medication.
Your doctor will determine the frequency of your blood tests based on your situation. However, regular monitoring is essential to ensure that cyclosporine works effectively and detects potential side effects.
If you miss a dose of Cyclostim 50 Softgel Capsule, take it as soon as you remember. However, if it's almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose.
Some people may experience mood changes or anxiety while taking Cyclostim 50 Softgel Capsule. If you notice any changes in your mental health, it's important to talk to your doctor.
Cyclostim 50 Softgel Capsule occasionally causes blurred vision or eye irritation. If you experience any vision problems, contact your doctor.
Before using this medication, you should inform your doctor about your medical history, including any ongoing medicines, to avoid potential interactions and minimize side effects.
Taking more than the recommended dosage does not provide additional benefit and can increase the risk of adverse effects.
Cyclostim 50 Softgel Capsule contains cyclosporine, an immunosuppressant.
Cyclostim 50 Softgel Capsule should not be given to children, as the efficacy and safety have not been established.

Country of origin

India

Manufacturer/Marketer address

Zydus Tower, Satellite Cross Roads,Ahmedabad - 380015 Gujarat, India.
Other Info - CYC0232

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