Naproplat 450mg Injection belongs to a group of anti-cancer medicines used for the treatment of ovarian cancer and small-cell lung cancer. It may sometimes be used to treat other cancers. Cancer forms in tissues of the ovary (one of a pair of female reproductive glands in which the ova, or eggs, are formed). Small-cell lung cancer is a disease in which malignant (cancer) cells form in the tissues of the lung.

Naproplat 450mg Injection contains 'Carboplatin'. Carboplatin acts by penetrating the cell wall and binding to the cell's DNA, stopping the cell from naturally dividing and functioning, ultimately destroying the cell. These medicines target cancer cells because they often affect rapidly dividing cells.

Naproplat 450mg Injection is prescribed by a doctor experienced in the use of medications to treat cancer. It is administered by a healthcare professional as an injection. You may experience nausea, diarrhoea, vomiting, thrombocytopenia (a low platelet count), peripheral neuropathy (nerves malfunction), nephrotoxicity at high doses and electrolyte disturbances. Most of these side effects of Naproplat 450mg Injection do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

To treat your condition effectually, continue taking Naproplat 450mg Injection for as long as your doctor has prescribed. Do not stop the Naproplat 450mg Injection midway. Talk to your doctor before taking Naproplat 450mg Injection if you have severe allergic reactions to Naproplat 450mg Injection or other platinum-containing compounds or if you are suffering from peripheral neuropathy (nerves malfunction), hypotension, cardiac disorders, severe lung problems, pulmonary disorders, posterior reversible encephalopathy syndrome disorders, gastrointestinal disorders, thrombocytopenia (a low platelet count), neutropenia (low white blood cell count), tumour lysis syndrome (metabolic abnormalities that can occur as a complication during the treatment of cancer), hepatic disorders. Naproplat 450mg Injection should not be employed in patients with severe bone marrow depression or significant bleeding. Avoid taking Naproplat 450mg Injection if you are pregnant or breastfeeding because this Naproplat 450mg Injection can cause harmful effects on the unborn baby. Both women and men using this Naproplat 450mg Injection should use birth control to avoid pregnancy.

Naproplat 450mg Injection contains 'Carboplatin' which belongs to a group of anti-cancer medicines used to treat ovarian cancer and small cell lung cancer. It works by damaging the genetic material (DNA) of the cancer cells, which stops their growth and multiplication. It can be used alone or with other chemotherapy drugs depending on your cancer type.

• Nausea
• Vomiting
• Diarrhoea
• Loss of appetite
• Hair loss and numbness
• Tingling
• Burning
• Pain in the hands or feet
• Nephrotoxicity at high doses
• Electrolyte disturbances
• Thrombocytopenia (low blood platelet count)
• Peripheral neuropathy (nerves malfunction)
• Leukopenia (low white blood cell count)

Naproplat 450mg Injection should be taken under strict medical supervision. The doctor will regularly monitor your condition while taking Naproplat 450mg Injection. To treat your condition effectually, continue taking Naproplat 450mg Injection for as long as your doctor has prescribed. Do not stop the Naproplat 450mg Injection midway. Talk to your doctor before taking Naproplat 450mg Injection if you have severe allergic reactions to Naproplat 450mg Injection or other platinum-containing compounds or if you are suffering from peripheral neuropathy (nerves malfunction), hypotension, cardiac disorders, severe lung problems, pulmonary disorders, posterior reversible encephalopathy syndrome disorders, gastrointestinal disorders, thrombocytopenia (a low platelet count), neutropenia (low white blood cell count), tumour lysis syndrome (metabolic abnormalities that can occur as a complication during the treatment of cancer), hepatic disorders. Naproplat 450mg Injection should not be employed in patients with severe bone marrow depression or significant bleeding. Avoid taking Naproplat 450mg Injection if you are pregnant or breastfeeding because this Naproplat 450mg Injection can cause harmful effects on the unborn baby. Both women and men using this Naproplat 450mg Injection should use birth control to avoid pregnancy. Peripheral blood counts should be frequently monitored during Naproplat 450mg Injection treatment and appropriate until recovery is achieved.

Drug-Drug Interactions: Naproplat 450mg Injection interacts with medicines used in the treatment of chemotherapy (e.g. pemetrexed, gemcitabine, pegfilgrastim, paclitaxel, docetaxel), antacid medications (e.g. pantoprazole) and antibiotic medications (e.g. amikacin, gentamicin, kanamycin, streptomycin, tobramycin).

Drug-Food Interactions: No food interaction was found.

Drug-Disease Interactions: Inform your doctor before taking Naproplat 450mg Injection it requires close monitoring if you are suffering from Infection (bacterial/fungal/protozoal/viral), bleeding disorders, bone marrow depression/low blood counts, fever, renal dysfunction or disorders, peripheral neuropathy (nerves malfunction).

• PEMETREXED
• GEMCITABINE
• PEGFILGRASTIM
• PACLITAXEL
• PANTOPRAZOLE
• AMIKACIN
• GENTAMICIN
• KANAMYCIN
• STREPTOMYCIN
• TOBRAMYCIN
• DOCETAXEL

• Eat a healthy diet and exercise regularly to maintain proper weight.
• Include leafy vegetables, citrus fruits, fatty fish, berries, yoghurt, apples, peaches, cauliflower, cabbage, broccoli, beans, and herbs in your diet.
• Get optimal sleep; rest well.
• Performing yoga may also help in improving both physical and mental health.
• Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
• De-stress yourself by meditating, reading books, taking a warm bubble bath or listening to soothing music.
• Avoid smoking and alcohol consumption.
• Avoid fast food, fried food, processed meats, refined carbs and added sugars.

• Peripheral blood counts should be frequently monitored during carboplatin treatment and, when appropriate, until recovery is achieved.
• Naproplat 450mg Injection should be taken under strict medical supervision. The doctor will regularly monitor your condition while taking Naproplat 450mg Injection.
• Your doctor may get routine blood tests done to monitor your liver function, electrolyte levels, and blood cell count in your blood.
• Avoid unnecessary or prolonged exposure to sunlight and UV light (such as tanning booths) and wear protective clothing, sunglasses, and sunscreen. Naproplat 450mg Injection may make your skin sensitive to sunlight.

Ovarian cancer: Cancer that forms in tissues of the ovary (one of a pair of female reproductive glands in which the ova, or eggs, are formed).

Small-cell lung cancer is a disease in which malignant (cancer) cells form in the tissues of the lung.