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Karplat 450mg Infusion

Karplat 450mg Infusion

Prescription drug
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Consult Doctor

Manufacturer/Marketer

Cadila Pharmaceuticals Ltd

Consume Type

PARENTERAL

Return Policy

Not Returnable

for this medicine

About Karplat 450mg Infusion

Karplat 450mg Infusion belongs to a group of anti-cancer medicines used for the treatment of ovarian cancer and small-cell lung cancer. It may sometimes be used to treat other cancers. Cancer forms in tissues of the ovary (one of a pair of female reproductive glands in which the ova, or eggs, are formed). Small-cell lung cancer is a disease in which malignant (cancer) cells form in the tissues of the lung.

Karplat 450mg Infusion contains 'Carboplatin'. Carboplatin acts by penetrating the cell wall and binding to the cell's DNA, stopping the cell from naturally dividing and functioning, ultimately destroying the cell. These medicines target cancer cells because they often affect rapidly dividing cells.

Karplat 450mg Infusion is prescribed by a doctor experienced in the use of medications to treat cancer. It is administered by a healthcare professional as an injection. You may experience nausea, diarrhoea, vomiting, thrombocytopenia (a low platelet count), peripheral neuropathy (nerves malfunction), nephrotoxicity at high doses and electrolyte disturbances. Most of these side effects of Karplat 450mg Infusion do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

To treat your condition effectually, continue taking Karplat 450mg Infusion for as long as your doctor has prescribed. Do not stop the Karplat 450mg Infusion midway. Talk to your doctor before taking Karplat 450mg Infusion if you have severe allergic reactions to Karplat 450mg Infusion or other platinum-containing compounds or if you are suffering from peripheral neuropathy (nerves malfunction), hypotension, cardiac disorders, severe lung problems, pulmonary disorders, posterior reversible encephalopathy syndrome disorders, gastrointestinal disorders, thrombocytopenia (a low platelet count), neutropenia (low white blood cell count), tumour lysis syndrome (metabolic abnormalities that can occur as a complication during the treatment of cancer), hepatic disorders. Karplat 450mg Infusion should not be employed in patients with severe bone marrow depression or significant bleeding. Avoid taking Karplat 450mg Infusion if you are pregnant or breastfeeding because this Karplat 450mg Infusion can cause harmful effects on the unborn baby. Both women and men using this Karplat 450mg Infusion should use birth control to avoid pregnancy.

Uses of Karplat 450mg Infusion

Treatment of Ovarian cancer and Small cell lung cancer

Medicinal Benefits

Karplat 450mg Infusion contains 'Carboplatin' which belongs to a group of anti-cancer medicines used to treat ovarian cancer and small cell lung cancer. It works by damaging the genetic material (DNA) of the cancer cells, which stops their growth and multiplication. It can be used alone or with other chemotherapy drugs depending on your cancer type.

Directions for Use

Parenteral: Karplat 450mg Infusion will be administered by a qualified healthcare professional. Kindly do not self-administer.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Karplat 450mg Infusion

  • Nausea
  • Vomiting
  • Diarrhoea
  • Loss of appetite
  • Hair loss and numbness
  • Tingling
  • Burning
  • Pain in the hands or feet
  • Nephrotoxicity at high doses
  • Electrolyte disturbances
  • Thrombocytopenia (low blood platelet count)
  • Peripheral neuropathy (nerves malfunction)
  • Leukopenia (low white blood cell count)

Drug Warnings

Karplat 450mg Infusion should be taken under strict medical supervision. The doctor will regularly monitor your condition while taking Karplat 450mg Infusion. To treat your condition effectually, continue taking Karplat 450mg Infusion for as long as your doctor has prescribed. Do not stop the Karplat 450mg Infusion midway. Talk to your doctor before taking Karplat 450mg Infusion if you have severe allergic reactions to Karplat 450mg Infusion or other platinum-containing compounds or if you are suffering from peripheral neuropathy (nerves malfunction), hypotension, cardiac disorders, severe lung problems, pulmonary disorders, posterior reversible encephalopathy syndrome disorders, gastrointestinal disorders, thrombocytopenia (a low platelet count), neutropenia (low white blood cell count), tumour lysis syndrome (metabolic abnormalities that can occur as a complication during the treatment of cancer), hepatic disorders. Karplat 450mg Infusion should not be employed in patients with severe bone marrow depression or significant bleeding. Avoid taking Karplat 450mg Infusion if you are pregnant or breastfeeding because this Karplat 450mg Infusion can cause harmful effects on the unborn baby. Both women and men using this Karplat 450mg Infusion should use birth control to avoid pregnancy. Peripheral blood counts should be frequently monitored during Karplat 450mg Infusion treatment and appropriate until recovery is achieved.

Drug Interactions

Drug-Drug Interactions: Karplat 450mg Infusion interacts with medicines used in the treatment of chemotherapy (e.g. pemetrexed, gemcitabine, pegfilgrastim, paclitaxel, docetaxel), antacid medications (e.g. pantoprazole) and antibiotic medications (e.g. amikacin, gentamicin, kanamycin, streptomycin, tobramycin).

Drug-Food Interactions: No food interaction was found.

Drug-Disease Interactions: Inform your doctor before taking Karplat 450mg Infusion it requires close monitoring if you are suffering from Infection (bacterial/fungal/protozoal/viral), bleeding disorders, bone marrow depression/low blood counts, fever, renal dysfunction or disorders, peripheral neuropathy (nerves malfunction).

Drug-Drug Interactions Checker List

  • PEMETREXED
  • GEMCITABINE
  • PEGFILGRASTIM
  • PACLITAXEL
  • PANTOPRAZOLE
  • AMIKACIN
  • GENTAMICIN
  • KANAMYCIN
  • STREPTOMYCIN
  • TOBRAMYCIN
  • DOCETAXEL

Habit Forming

No

Diet & Lifestyle Advise

  • Eat a healthy diet and exercise regularly to maintain proper weight.
  • Include leafy vegetables, citrus fruits, fatty fish, berries, yoghurt, apples, peaches, cauliflower, cabbage, broccoli, beans, and herbs in your diet.
  • Get optimal sleep; rest well.
  • Performing yoga may also help in improving both physical and mental health.
  • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
  • De-stress yourself by meditating, reading books, taking a warm bubble bath or listening to soothing music.
  • Avoid smoking and alcohol consumption.
  • Avoid fast food, fried food, processed meats, refined carbs and added sugars.

Special Advise

  • Peripheral blood counts should be frequently monitored during carboplatin treatment and, when appropriate, until recovery is achieved.
  • Karplat 450mg Infusion should be taken under strict medical supervision. The doctor will regularly monitor your condition while taking Karplat 450mg Infusion.
  • Your doctor may get routine blood tests done to monitor your liver function, electrolyte levels, and blood cell count in your blood.
  • Avoid unnecessary or prolonged exposure to sunlight and UV light (such as tanning booths) and wear protective clothing, sunglasses, and sunscreen. Karplat 450mg Infusion may make your skin sensitive to sunlight.

Disease/Condition Glossary

Ovarian cancer: Cancer that forms in tissues of the ovary (one of a pair of female reproductive glands in which the ova, or eggs, are formed).

Small-cell lung cancer is a disease in which malignant (cancer) cells form in the tissues of the lung.

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Alcohol

Caution

You are recommended to avoid alcohol consumption while taking Karplat 450mg Infusion. It could lead to avoiding unpleasant side effects.

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Pregnancy

Unsafe

Karplat 450mg Infusion should not be used during pregnancy because it causes harm to the fetus (newborn baby). Both women of childbearing potential and men must use an effective contraception method while taking Karplat 450mg Infusion and at least six months afterwards. Please consult your doctor about any concerns regarding this.

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Breast Feeding

Unsafe

Karplat 450mg Infusion should not be taken during breastfeeding as it passes into the breastmilk and may harm the nursing baby. It is contraindicated in breastfeeding mothers. Please consult your doctor about any concerns regarding this.

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Driving

Caution

Karplat 450mg Infusion may affect your reactions and your ability to drive. Possible side effects of chemotherapy with Karplat 450mg Infusion may occur, such as nausea and vomiting. If you are affected by these side effects, you should not drive and/or operate machines that require you to be alert.

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Liver

Caution

If you have had a history or evidence of any liver-related diseases, please consult the doctor before taking Karplat 450mg Infusion. Your doctor will weigh the benefits and any potential risks before prescribing it to you.

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Kidney

Caution

If you have had a history or evidence of any kidney-related diseases, please consult the doctor before taking Karplat 450mg Infusion. Your doctor will weigh the benefits and any potential risks before prescribing it to you.

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Children

Unsafe

Efficacy and safety have not been established. Please consult your doctor. Your doctor will weigh the benefits and potential risks before prescribing them.

Country of origin

India
Other Info - KA71925

Author Details

Doctor imageWe provide you with authentic, trustworthy and relevant information

FAQs

Karplat 450mg Infusion is used to treat ovarian cancer and small-cell lung cancer.
Karplat 450mg Infusion contains 'Carboplatin'. Carboplatin works by breaching the cellular wall and binding to the cell’s DNA, preventing the cell from dividing and functioning normally, which eventually kills the cell.
Yes, Karplat 450mg Infusion can cause low neutrophils levels, a type of white blood cells that help fight infections. If your white blood cells become low, you can be at higher risk for infections. Tell your doctor if you develop a fever or believe you have an infection.
Karplat 450mg Infusion should be administered under the supervision of a qualified physician experienced in the use of cancer chemotherapeutic agents.
Before you receive treatment with Karplat 450mg Infusion, tell your doctor about all of your medical conditions. You should not receive Karplat 450mg Infusion if you are allergic to carboplatin or any contents in Karplat 450mg Infusion. It should not be employed in patients with severe bone marrow depression or significant bleeding.
If not given an inappropriate dose, Karplat 450mg Infusion can cause toxic effects, although not everyone gets it. So, Karplat 450mg Infusion is prescribed by a doctor experienced in the use of medications to treat cancer only.
Avoid taking Karplat 450mg Infusion if you are pregnant because Karplat 450mg Infusion can cause harmful effects on the unborn baby. Females should follow effective birth control methods during treatment and at least six months after the final dose of Karplat 450mg Infusion.

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