apollo
0
Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Karplat 450mg Infusion is used to treat ovarian cancer and small-cell lung cancer. It contains Carboplatin which works by stopping the cancer cells from naturally dividing and functioning. In some cases, this medicine may cause side effects such as nausea, diarrhoea, vomiting, and a low platelet count. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.
Read more
rxMedicinePrescription drug

Whats That

tooltip
Consult Doctor

Composition :

CARBOPLATIN-450MG

Manufacturer/Marketer :

Cadila Pharmaceuticals Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

About Karplat 450mg Infusion

Karplat 450mg Infusion belongs to a group of anti-cancer medicines used for the treatment of ovarian cancer and small-cell lung cancer. It may sometimes be used to treat other cancers. Cancer forms in tissues of the ovary (one of a pair of female reproductive glands in which the ova, or eggs, are formed). Small-cell lung cancer is a disease in which malignant (cancer) cells form in the tissues of the lung.

Karplat 450mg Infusion contains 'Carboplatin'. Carboplatin acts by penetrating the cell wall and binding to the cell's DNA, stopping the cell from naturally dividing and functioning, ultimately destroying the cell. These medicines target cancer cells because they often affect rapidly dividing cells.

Karplat 450mg Infusion is prescribed by a doctor experienced in the use of medications to treat cancer. It is administered by a healthcare professional as an injection. You may experience nausea, diarrhoea, vomiting, thrombocytopenia (a low platelet count), peripheral neuropathy (nerves malfunction), nephrotoxicity at high doses and electrolyte disturbances. Most of these side effects of Karplat 450mg Infusion do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

To treat your condition effectually, continue taking Karplat 450mg Infusion for as long as your doctor has prescribed. Do not stop the Karplat 450mg Infusion midway. Talk to your doctor before taking Karplat 450mg Infusion if you have severe allergic reactions to Karplat 450mg Infusion or other platinum-containing compounds or if you are suffering from peripheral neuropathy (nerves malfunction), hypotension, cardiac disorders, severe lung problems, pulmonary disorders, posterior reversible encephalopathy syndrome disorders, gastrointestinal disorders, thrombocytopenia (a low platelet count), neutropenia (low white blood cell count), tumour lysis syndrome (metabolic abnormalities that can occur as a complication during the treatment of cancer), hepatic disorders. Karplat 450mg Infusion should not be employed in patients with severe bone marrow depression or significant bleeding. Avoid taking Karplat 450mg Infusion if you are pregnant or breastfeeding because this Karplat 450mg Infusion can cause harmful effects on the unborn baby. Both women and men using this Karplat 450mg Infusion should use birth control to avoid pregnancy.

Uses of Karplat 450mg Infusion

Treatment of Ovarian cancer and Small cell lung cancer

Directions for Use

Parenteral: Karplat 450mg Infusion will be administered by a qualified healthcare professional. Kindly do not self-administer.

Medicinal Benefits

Karplat 450mg Infusion contains 'Carboplatin' which belongs to a group of anti-cancer medicines used to treat ovarian cancer and small cell lung cancer. It works by damaging the genetic material (DNA) of the cancer cells, which stops their growth and multiplication. It can be used alone or with other chemotherapy drugs depending on your cancer type.

How Karplat 450mg Infusion Works

Karplat 450mg Infusion contains 'Carboplatin'. Carboplatin acts by penetrating the cell wall and binding to the cell's DNA, stopping the cell from naturally dividing and functioning, ultimately destroying the cell. These medicines target cancer cells because they often affect rapidly dividing cells.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Karplat 450mg Infusion

  • Nausea
  • Vomiting
  • Diarrhoea
  • Loss of appetite
  • Hair loss and numbness
  • Tingling
  • Burning
  • Pain in the hands or feet
  • Nephrotoxicity at high doses
  • Electrolyte disturbances
  • Thrombocytopenia (low blood platelet count)
  • Peripheral neuropathy (nerves malfunction)
  • Leukopenia (low white blood cell count)

What if I have taken an overdose of Karplat 450mg Infusion

It is unlikely to overdose on parenteral medication as it is administered by a healthcare professional. However, seek medical attention if you experience symptoms of overdose such as black/tarry/bloody stools, bloody vomit or vomited material that looks like coffee grounds, unusual bruising or bleeding, decreased urination, pain, burning, or tingling in the hands or feet, ringing in ears and difficulty hearing.

Drug Warnings

Karplat 450mg Infusion should be taken under strict medical supervision. The doctor will regularly monitor your condition while taking Karplat 450mg Infusion. To treat your condition effectually, continue taking Karplat 450mg Infusion for as long as your doctor has prescribed. Do not stop the Karplat 450mg Infusion midway. Talk to your doctor before taking Karplat 450mg Infusion if you have severe allergic reactions to Karplat 450mg Infusion or other platinum-containing compounds or if you are suffering from peripheral neuropathy (nerves malfunction), hypotension, cardiac disorders, severe lung problems, pulmonary disorders, posterior reversible encephalopathy syndrome disorders, gastrointestinal disorders, thrombocytopenia (a low platelet count), neutropenia (low white blood cell count), tumour lysis syndrome (metabolic abnormalities that can occur as a complication during the treatment of cancer), hepatic disorders. Karplat 450mg Infusion should not be employed in patients with severe bone marrow depression or significant bleeding. Avoid taking Karplat 450mg Infusion if you are pregnant or breastfeeding because this Karplat 450mg Infusion can cause harmful effects on the unborn baby. Both women and men using this Karplat 450mg Infusion should use birth control to avoid pregnancy. Peripheral blood counts should be frequently monitored during Karplat 450mg Infusion treatment and appropriate until recovery is achieved.

Diet & Lifestyle Advise

  • Eat a healthy diet and exercise regularly to maintain proper weight.
  • Include leafy vegetables, citrus fruits, fatty fish, berries, yoghurt, apples, peaches, cauliflower, cabbage, broccoli, beans, and herbs in your diet.
  • Get optimal sleep; rest well.
  • Performing yoga may also help in improving both physical and mental health.
  • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
  • De-stress yourself by meditating, reading books, taking a warm bubble bath or listening to soothing music.
  • Avoid smoking and alcohol consumption.
  • Avoid fast food, fried food, processed meats, refined carbs and added sugars.

Habit Forming

No

Therapeutic Class

CHEMOTHERAPY

Karplat 450mg Infusion Substitute

Substitutes safety advice
  • CARBOPLATIN 450MG INJECTION 45ML

    58.21per tablet
  • Kemocarb 450 mg Injection 45 ml

    54.24per tablet
  • Carbopa 450 Injection 45 ml

    54.25per tablet
  • CARBOKEM NOVA 450MG INJECTION

    2177.10per tablet
  • UNICARB 450MG INJECTION

    53.10per tablet
bannner image

Alcohol

Caution

You are recommended to avoid alcohol consumption while taking Karplat 450mg Infusion. It could lead to avoiding unpleasant side effects.

bannner image

Pregnancy

Unsafe

Karplat 450mg Infusion should not be used during pregnancy because it causes harm to the fetus (newborn baby). Both women of childbearing potential and men must use an effective contraception method while taking Karplat 450mg Infusion and at least six months afterwards. Please consult your doctor about any concerns regarding this.

bannner image

Breast Feeding

Unsafe

Karplat 450mg Infusion should not be taken during breastfeeding as it passes into the breastmilk and may harm the nursing baby. It is contraindicated in breastfeeding mothers. Please consult your doctor about any concerns regarding this.

bannner image

Driving

Caution

Karplat 450mg Infusion may affect your reactions and your ability to drive. Possible side effects of chemotherapy with Karplat 450mg Infusion may occur, such as nausea and vomiting. If you are affected by these side effects, you should not drive and/or operate machines that require you to be alert.

bannner image

Liver

Caution

If you have had a history or evidence of any liver-related diseases, please consult the doctor before taking Karplat 450mg Infusion. Your doctor will weigh the benefits and any potential risks before prescribing it to you.

bannner image

Kidney

Caution

If you have had a history or evidence of any kidney-related diseases, please consult the doctor before taking Karplat 450mg Infusion. Your doctor will weigh the benefits and any potential risks before prescribing it to you.

bannner image

Children

Unsafe

Efficacy and safety have not been established. Please consult your doctor. Your doctor will weigh the benefits and potential risks before prescribing them.

FAQs

Karplat 450mg Infusion is used to treat ovarian cancer and small-cell lung cancer.
Karplat 450mg Infusion contains 'Carboplatin'. Carboplatin works by breaching the cellular wall and binding to the cell’s DNA, preventing the cell from dividing and functioning normally, which eventually kills the cell.
Yes, Karplat 450mg Infusion can cause low neutrophils levels, a type of white blood cells that help fight infections. If your white blood cells become low, you can be at higher risk for infections. Tell your doctor if you develop a fever or believe you have an infection.
Karplat 450mg Infusion should be administered under the supervision of a qualified physician experienced in the use of cancer chemotherapeutic agents.
Before you receive treatment with Karplat 450mg Infusion, tell your doctor about all of your medical conditions. You should not receive Karplat 450mg Infusion if you are allergic to carboplatin or any contents in Karplat 450mg Infusion. It should not be employed in patients with severe bone marrow depression or significant bleeding.
If not given an inappropriate dose, Karplat 450mg Infusion can cause toxic effects, although not everyone gets it. So, Karplat 450mg Infusion is prescribed by a doctor experienced in the use of medications to treat cancer only.
Avoid taking Karplat 450mg Infusion if you are pregnant because Karplat 450mg Infusion can cause harmful effects on the unborn baby. Females should follow effective birth control methods during treatment and at least six months after the final dose of Karplat 450mg Infusion.
Karplat 450mg Infusion is administered to you through an intravenous (IV) infusion. A healthcare professional usually gives it in a medical facility.
Karplat 450mg Infusion is not cell cycle specific. It works by forming DNA adducts, which leads to cell death. This mechanism of action is not specific to any particular phase of the cell cycle, meaning it can affect cells at various stages of their life cycle.
Yes, Karplat 450mg Infusion is FDA approved. It was approved on 3 March 1989.
Yes, Karplat 450mg Infusion is a platinum-containing compound medication that works by stopping or slowing the growth of cancer cells.
Karplat 450mg Infusion may cause side effects, including neuropathy (tingling and numbness) in the hands and feet, hearing loss, temporary hair loss, and constipation. Weight gain is rare but possible. While leukemia is not typically associated with Karplat 450mg Infusion, the long-term use of any chemotherapy drug can increase the risk of secondary cancers. It's important to discuss any side effects with your doctor to manage them effectively.
Karplat 450mg Infusion is not a vesicant, and it does not cause blistering or tissue damage if it leaks out of the vein. It is also not cardio-toxic, so it does not specifically target the heart. Additionally, Carboplatin is not an anthracycline, as it does not belong to that class of platinum-containing compounds.
Yes, sometimes the doctor may suggest Karplat 450mg Infusion to treat breast cancer based on your health situation. It is often given in combination with other chemotherapy drugs for optimal results.
Karplat 450mg Infusion is not available in pill form; It is available in two primary dosage forms: injection and powder for injection.
The common side effects of the Karplat 450mg Infusion are nausea, vomiting, diarrhoea, constipation, sores in the mouth and throat, pain, burning, or tingling in the hands or feet, pain, itching, redness, swelling, blisters, or sores in the place where the medication was injected, hair loss, pain, weakness, loss in ability to taste food. However, these symptoms vanish as your body adjusts to the medication. If these symptoms become worse, please consult a doctor for relief.
The efficacy and safety of Karplat 450mg Infusion have yet to be established for using children. Please consult your doctor. The doctor will help determine whether the potential benefits outweigh the possible risks and make the appropriate recommendation.

Country of origin

India
Other Info - KA71925

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
whatsapp Floating Button