apollo
0
Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Nov 23, 2024 | 4:46 PM IST
Carbenz 450 Injection is used to treat ovarian cancer and small-cell lung cancer. It contains Carboplatin which works by stopping the cancer cells from naturally dividing and functioning. In some cases, this medicine may cause side effects such as nausea, diarrhoea, vomiting, and a low platelet count. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.
Read more
Prescription drug

Whats That

tooltip
Prescription drug
 Trailing icon
Consult Doctor

Composition :

CARBOPLATIN-450MG

Manufacturer/Marketer :

Admac Lifesciences(Oncology)

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

Apr-26

About Carbenz 450 Injection

Carbenz 450 Injection belongs to a group of anti-cancer medicines used for the treatment of ovarian cancer and small-cell lung cancer. It may sometimes be used to treat other cancers. Cancer forms in tissues of the ovary (one of a pair of female reproductive glands in which the ova, or eggs, are formed). Small-cell lung cancer is a disease in which malignant (cancer) cells form in the tissues of the lung.

Carbenz 450 Injection contains 'Carboplatin'. Carboplatin acts by penetrating the cell wall and binding to the cell's DNA, stopping the cell from naturally dividing and functioning, ultimately destroying the cell. These medicines target cancer cells because they often affect rapidly dividing cells.

Carbenz 450 Injection is prescribed by a doctor experienced in the use of medications to treat cancer. It is administered by a healthcare professional as an injection. You may experience nausea, diarrhoea, vomiting, thrombocytopenia (a low platelet count), peripheral neuropathy (nerves malfunction), nephrotoxicity at high doses and electrolyte disturbances. Most of these side effects of Carbenz 450 Injection do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

To treat your condition effectually, continue taking Carbenz 450 Injection for as long as your doctor has prescribed. Do not stop the Carbenz 450 Injection midway. Talk to your doctor before taking Carbenz 450 Injection if you have severe allergic reactions to Carbenz 450 Injection or other platinum-containing compounds or if you are suffering from peripheral neuropathy (nerves malfunction), hypotension, cardiac disorders, severe lung problems, pulmonary disorders, posterior reversible encephalopathy syndrome disorders, gastrointestinal disorders, thrombocytopenia (a low platelet count), neutropenia (low white blood cell count), tumour lysis syndrome (metabolic abnormalities that can occur as a complication during the treatment of cancer), hepatic disorders. Carbenz 450 Injection should not be employed in patients with severe bone marrow depression or significant bleeding. Avoid taking Carbenz 450 Injection if you are pregnant or breastfeeding because this Carbenz 450 Injection can cause harmful effects on the unborn baby. Both women and men using this Carbenz 450 Injection should use birth control to avoid pregnancy.

Uses of Carbenz 450 Injection

Treatment of Ovarian cancer and Small cell lung cancer

Medicinal Benefits

Carbenz 450 Injection contains 'Carboplatin' which belongs to a group of anti-cancer medicines used to treat ovarian cancer and small cell lung cancer. It works by damaging the genetic material (DNA) of the cancer cells, which stops their growth and multiplication. It can be used alone or with other chemotherapy drugs depending on your cancer type.

Side Effects of Carbenz 450 Injection

  • Nausea
  • Vomiting
  • Diarrhoea
  • Loss of appetite
  • Hair loss and numbness
  • Tingling
  • Burning
  • Pain in the hands or feet
  • Nephrotoxicity at high doses
  • Electrolyte disturbances
  • Thrombocytopenia (low blood platelet count)
  • Peripheral neuropathy (nerves malfunction)
  • Leukopenia (low white blood cell count)

Directions for Use

Parenteral: Carbenz 450 Injection will be administered by a qualified healthcare professional. Kindly do not self-administer.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Carbenz 450 Injection should be taken under strict medical supervision. The doctor will regularly monitor your condition while taking Carbenz 450 Injection. To treat your condition effectually, continue taking Carbenz 450 Injection for as long as your doctor has prescribed. Do not stop the Carbenz 450 Injection midway. Talk to your doctor before taking Carbenz 450 Injection if you have severe allergic reactions to Carbenz 450 Injection or other platinum-containing compounds or if you are suffering from peripheral neuropathy (nerves malfunction), hypotension, cardiac disorders, severe lung problems, pulmonary disorders, posterior reversible encephalopathy syndrome disorders, gastrointestinal disorders, thrombocytopenia (a low platelet count), neutropenia (low white blood cell count), tumour lysis syndrome (metabolic abnormalities that can occur as a complication during the treatment of cancer), hepatic disorders. Carbenz 450 Injection should not be employed in patients with severe bone marrow depression or significant bleeding. Avoid taking Carbenz 450 Injection if you are pregnant or breastfeeding because this Carbenz 450 Injection can cause harmful effects on the unborn baby. Both women and men using this Carbenz 450 Injection should use birth control to avoid pregnancy. Peripheral blood counts should be frequently monitored during Carbenz 450 Injection treatment and appropriate until recovery is achieved.

Therapeutic Class

CHEMOTHERAPY

Drug-Drug Interactions

verifiedApollotooltip
CarboplatinSorafenib
Critical
CarboplatinCertolizumab
Severe

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Diet & Lifestyle Advise

  • Eat a healthy diet and exercise regularly to maintain proper weight.
  • Include leafy vegetables, citrus fruits, fatty fish, berries, yoghurt, apples, peaches, cauliflower, cabbage, broccoli, beans, and herbs in your diet.
  • Get optimal sleep; rest well.
  • Performing yoga may also help in improving both physical and mental health.
  • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
  • De-stress yourself by meditating, reading books, taking a warm bubble bath or listening to soothing music.
  • Avoid smoking and alcohol consumption.
  • Avoid fast food, fried food, processed meats, refined carbs and added sugars.

Habit Forming

No

What if I have taken an overdose of Carbenz 450 Injection

It is unlikely to overdose on parenteral medication as it is administered by a healthcare professional. However, seek medical attention if you experience symptoms of overdose such as black/tarry/bloody stools, bloody vomit or vomited material that looks like coffee grounds, unusual bruising or bleeding, decreased urination, pain, burning, or tingling in the hands or feet, ringing in ears and difficulty hearing.
bannner image

Alcohol

Caution

You are recommended to avoid alcohol consumption while taking Carbenz 450 Injection. It could lead to avoiding unpleasant side effects.

bannner image

Pregnancy

Unsafe

Carbenz 450 Injection should not be used during pregnancy because it causes harm to the fetus (newborn baby). Both women of childbearing potential and men must use an effective contraception method while taking Carbenz 450 Injection and at least six months afterwards. Please consult your doctor about any concerns regarding this.

bannner image

Breast Feeding

Unsafe

Carbenz 450 Injection should not be taken during breastfeeding as it passes into the breastmilk and may harm the nursing baby. It is contraindicated in breastfeeding mothers. Please consult your doctor about any concerns regarding this.

bannner image

Driving

Caution

Carbenz 450 Injection may affect your reactions and your ability to drive. Possible side effects of chemotherapy with Carbenz 450 Injection may occur, such as nausea and vomiting. If you are affected by these side effects, you should not drive and/or operate machines that require you to be alert.

bannner image

Liver

Caution

If you have had a history or evidence of any liver-related diseases, please consult the doctor before taking Carbenz 450 Injection. Your doctor will weigh the benefits and any potential risks before prescribing it to you.

bannner image

Kidney

Caution

If you have had a history or evidence of any kidney-related diseases, please consult the doctor before taking Carbenz 450 Injection. Your doctor will weigh the benefits and any potential risks before prescribing it to you.

bannner image

Children

Unsafe

Efficacy and safety have not been established. Please consult your doctor. Your doctor will weigh the benefits and potential risks before prescribing them.

Country of origin

India

Manufacturer/Marketer address

SCO 84, Sector 5, Panchkula (Haryana) 134112 INDIA.
Other Info - CAR0888

Author Details

Doctor imageWe provide you with authentic, trustworthy and relevant information

FAQs

Carbenz 450 Injection is used to treat ovarian cancer and small-cell lung cancer.
Carbenz 450 Injection contains 'Carboplatin'. Carboplatin works by breaching the cellular wall and binding to the cell’s DNA, preventing the cell from dividing and functioning normally, which eventually kills the cell.
Yes, Carbenz 450 Injection can cause low neutrophils levels, a type of white blood cells that help fight infections. If your white blood cells become low, you can be at higher risk for infections. Tell your doctor if you develop a fever or believe you have an infection.
Carbenz 450 Injection should be administered under the supervision of a qualified physician experienced in the use of cancer chemotherapeutic agents.
Before you receive treatment with Carbenz 450 Injection, tell your doctor about all of your medical conditions. You should not receive Carbenz 450 Injection if you are allergic to carboplatin or any contents in Carbenz 450 Injection. It should not be employed in patients with severe bone marrow depression or significant bleeding.
If not given an inappropriate dose, Carbenz 450 Injection can cause toxic effects, although not everyone gets it. So, Carbenz 450 Injection is prescribed by a doctor experienced in the use of medications to treat cancer only.
Avoid taking Carbenz 450 Injection if you are pregnant because Carbenz 450 Injection can cause harmful effects on the unborn baby. Females should follow effective birth control methods during treatment and at least six months after the final dose of Carbenz 450 Injection.
Carbenz 450 Injection is administered to you through an intravenous (IV) infusion. A healthcare professional usually gives it in a medical facility.
Carbenz 450 Injection is not cell cycle specific. It works by forming DNA adducts, which leads to cell death. This mechanism of action is not specific to any particular phase of the cell cycle, meaning it can affect cells at various stages of their life cycle.
Yes, Carbenz 450 Injection is FDA approved. It was approved on 3 March 1989.
Yes, Carbenz 450 Injection is a platinum-containing compound medication that works by stopping or slowing the growth of cancer cells.
Carbenz 450 Injection may cause side effects, including neuropathy (tingling and numbness) in the hands and feet, hearing loss, temporary hair loss, and constipation. Weight gain is rare but possible. While leukemia is not typically associated with Carbenz 450 Injection, the long-term use of any chemotherapy drug can increase the risk of secondary cancers. It's important to discuss any side effects with your doctor to manage them effectively.
Carbenz 450 Injection is not a vesicant, and it does not cause blistering or tissue damage if it leaks out of the vein. It is also not cardio-toxic, so it does not specifically target the heart. Additionally, Carboplatin is not an anthracycline, as it does not belong to that class of platinum-containing compounds.
Yes, sometimes the doctor may suggest Carbenz 450 Injection to treat breast cancer based on your health situation. It is often given in combination with other chemotherapy drugs for optimal results.
Carbenz 450 Injection is not available in pill form; It is available in two primary dosage forms: injection and powder for injection.
The common side effects of the Carbenz 450 Injection are nausea, vomiting, diarrhoea, constipation, sores in the mouth and throat, pain, burning, or tingling in the hands or feet, pain, itching, redness, swelling, blisters, or sores in the place where the medication was injected, hair loss, pain, weakness, loss in ability to taste food. However, these symptoms vanish as your body adjusts to the medication. If these symptoms become worse, please consult a doctor for relief.
The efficacy and safety of Carbenz 450 Injection have yet to be established for using children. Please consult your doctor. The doctor will help determine whether the potential benefits outweigh the possible risks and make the appropriate recommendation.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Add to Cart