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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy
Last Updated Oct 9, 2024 | 12:37 PM IST
Myzotem 250mg Capsule is an anti-cancer medicine used in the treatment of brain tumours such as glioblastoma multiforme (a type of tumour that grows and spreads rapidly) in adults and malignant glioma, including glioblastoma multiforme or anaplastic astrocytoma. This medicine works by inhibiting the production of DNA (deoxyribonucleic acid-genetic material of the cell), thereby affecting cell growth and division. Common side effects include loss of appetite, anxiety, confusion, headache, vomiting, nausea, diarrhoea, constipation, muscle weakness, muscle aches, and fever.
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Prescription drug

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Prescription drug
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Manufacturer/Marketer

Mylan Pharmaceuticals Pvt Ltd

Consume Type

ORAL

Return Policy

Not Returnable

for this medicine

About Myzotem 250mg Capsule

Myzotem 250mg Capsule belongs to a class of medicines called 'anti-cancer/ antitumor agent', used to treat specific forms of brain tumours such as glioblastoma multiforme (a type of tumour that grows and spreads rapidly) in adults and malignant glioma, including glioblastoma multiforme or anaplastic astrocytoma (a rare malignant brain tumour) in patients older than 3years. A brain tumour is an uncontrolled and unregulated proliferation of cells in the brain. 

Myzotem 250mg Capsule contains Temozolomide which works by inhibiting the production of DNA (deoxyribonucleic acid-genetic material of the cell), thereby affecting cell growth and division. Thus, Myzotem 250mg Capsule prevents tumours from growing.

Take Myzotem 250mg Capsule as prescribed. In some cases, Myzotem 250mg Capsule may cause loss of appetite, anxiety, confusion, headache, vomiting, nausea, diarrhoea, constipation, muscle weakness, muscle aches, and fever. Most of these side effects of Myzotem 250mg Capsule do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Let your doctor know if you are allergic to any of the contents. Myzotem 250mg Capsule is not recommended for patients with severe bone marrow depression or significant bleeding. Avoid taking Myzotem 250mg Capsule if you are pregnant or breastfeeding. Both women and men using Myzotem 250mg Capsule should use birth control to avoid pregnancy and fathering a child. It would be best not to drive and/or operate machines that require alertness as Myzotem 250mg Capsule may cause tiredness or sleepiness.

Uses of Myzotem 250mg Capsule

Treatment of Brain tumour

Medicinal Benefits

Myzotem 250mg Capsule belongs to a class of medicines called anti-cancer/antitumor agents used to treat specific forms of brain tumours such as glioblastoma multiforme (a type of tumour that grows and spreads rapidly) in adults and malignant glioma, including glioblastoma multiforme or anaplastic astrocytoma (a rare malignant brain tumour) in patients older than 3years. It contains Temozolomide which works by binding to the DNA (deoxyribonucleic acid-genetic material of the cell) and interfering with cell growth and division. Thus, Myzotem 250mg Capsule prevents tumours from growing.

Directions for Use

Swallow it as a whole with water; do not crush, break or chew it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Myzotem 250mg Capsule

  • Loss of appetite
  • Difficulty speaking
  • Headache
  • Vomiting
  • Nausea
  • Diarrhoea
  • Constipation
  • Rash
  • Hair loss
  • Tiredness
  • Infections
  • Fever
  • Increased blood sugar
  • Dry skin
  • Swelling
  • Weight loss/gain
  • Frequent urination

Drug Warnings

Myzotem 250mg Capsule should be taken under strict medical supervision. The doctor will regularly monitor your condition while taking Myzotem 250mg Capsule. To treat your condition effectually, continue taking Myzotem 250mg Capsule for as long as your doctor has prescribed. Do not stop Myzotem 250mg Capsule midway under any circumstances without consulting the healthcare professional. Inform your doctor if you have an allergy to any components of Myzotem 250mg Capsule. Inform your doctor before taking Myzotem 250mg Capsule if you have allergic reactions, infections, lung, renal or hepatic disorders or low blood count (including neutropenia, lymphopenia, thrombocytopenia). Myzotem 250mg Capsule is not recommended for patients with severe bone marrow depression or significant bleeding. Avoid taking Myzotem 250mg Capsule if you are pregnant or breastfeeding. Both women and men using Myzotem 250mg Capsule should use birth control to avoid pregnancy or fathering a child. Do not receive any vaccinations or immunizations without your doctor's approval while taking Myzotem 250mg Capsule.

Drug Interactions

Drug-Drug Interactions: Myzotem 250mg Capsule interacts with medicines used to treat infections (e.g. adalimumab), medicines used to treat rheumatoid arthritis (e.g. baricitinib, certolizumab, golimumab, infliximab, leflunomide, upadacitinib), medicines used to treat certain cancers (e.g. cladribine), medicines used to treat mental/mood disorders (e.g. clozapine), medicines used to treat multiple sclerosis (e.g. fingolimod, siponimod, teriflunomide),  cholesterol-lowering medications (e.g. lomitapide), and vaccines (e.g. BCG vaccine, influenza virus vaccine, measles virus vaccine, rotavirus vaccine, rubella virus vaccine smallpox vaccine, typhoid vaccine, varicella virus vaccine, yellow fever vaccine, zoster vaccine).

Drug-Food Interactions: Avoid the consumption of alcohol while taking Myzotem 250mg Capsule.

Drug-Disease Interactions: Inform your doctor before taking the Myzotem 250mg Capsule you are suffering from urticaria or allergic reactions, bleeding disorders, myelosuppression (bone marrow depression), low blood counts, hepatic or renal dysfunction or disorders.

Drug-Drug Interactions Checker List

  • ADALIMUMAB
  • BARICITINIB
  • CERTOLIZUMAB
  • GOLIMUMAB
  • INFLIXIMAB
  • LEFLUNOMIDE
  • UPADACITINIB
  • CLADRIBINE
  • CLOZAPINE
  • FINGOLIMOD
  • SIPONIMOD
  • TERIFLUNOMIDE
  • LOMITAPIDE
  • BCG VACCINE
  • INFLUENZA (LIVE ATTENUATED)
  • MEASLES (LIVE ATTENUATED)
  • ROTAVIRUS VACCINE
  • RUBELLA (LIVE ATTENUATED)
  • SMALLPOX VACCINE
  • TYPHOID VACCINE
  • VARICELLA (LIVE ATTENUATED)
  • YELLOW FEVER VACCINE
  • ZOSTER VACCINE LIVE

Habit Forming

No

Diet & Lifestyle Advise

  • De-stress yourself by meditating, reading books, taking a warm bubble bath or listening to soothing music.
  • Performing yoga may also help in improving both physical and mental health.
  • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
  • Eat a healthy diet and exercise regularly to maintain proper weight.
  • Include leafy vegetables, citrus fruits, fatty fish, berries, yoghurt, apples, peaches, cauliflower, cabbage, broccoli, beans, and herbs in your diet.
  • Get optimal sleep; rest well.
  • Avoid smoking and alcohol consumption.
  • Avoid fast food, fried food, processed meats, refined carbs and added sugars.

Special Advise

  • Myzotem 250mg Capsule should be taken under strict medical supervision. The doctor will regularly monitor your condition while taking Myzotem 250mg Capsule.
  • Your doctor may advise you to get routine blood tests done to monitor your liver function, electrolyte levels, and blood cell count.
  • Both male and female patients who are taking Myzotem 250mg Capsule must use effective contraceptive precautions. Women of childbearing potential must use effective contraception during the treatment and for 6months after completion of the treatment. Male patients should avoid fathering a child while on treatment with Myzotem 250mg Capsule and should use effective contraception during the treatment and for 3months after the treatment.

Disease/Condition Glossary

Brain tumour: A brain tumour is an uncontrolled, unregulated proliferation of cells in the brain. The cancerous cells can invade and destroy surrounding healthy tissue, including organs. The symptoms of a brain tumour differ depending on the tumour's location in the brain. Common symptoms include headaches, fits (seizures), feeling unwell or being sick all the time, behavioural changes, paralysis, sickness, eyesight or speech impairments.

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Alcohol

Caution

You are recommended to avoid alcohol consumption while taking Myzotem 250mg Capsule. It could lead to unpleasant side effects.

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Pregnancy

Caution

Please consult your doctor if you have any concerns about this. Myzotem 250mg Capsule should not be used during pregnancy unless prescribed by your doctor. Women of childbearing potential must use effective contraception during the treatment and for 6months after completion of the treatment.

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Breast Feeding

Unsafe

Myzotem 250mg Capsule should not be taken during breastfeeding as it passes into the breastmilk and may harm the baby.

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Driving

Caution

Myzotem 250mg Capsule may make you feel tired or sleepy. Drive and/or operate machines only if you are alert.

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Liver

Caution

If you have had a history or evidence of any liver-related diseases, please consult the doctor before using Myzotem 250mg Capsule. Your doctor will weigh the benefits and potential risks before prescribing Myzotem 250mg Capsule.

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Kidney

Caution

If you have had a history or evidence of any kidney-related diseases, please consult the doctor before using Myzotem 250mg Capsule. Your doctor will weigh the benefits and potential risks before prescribing Myzotem 250mg Capsule.

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Children

Caution

Safety and effectiveness of Myzotem 250mg Capsule in paediatric patients under the age of three have not been established.

Country of origin

India
Other Info - MY93675

Author Details

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FAQs

Myzotem 250mg Capsule belongs to a class of medicines called anti-cancer agents, used to treat specific forms of brain tumours such as glioblastoma multiforme (a type of tumour that grows and spreads rapidly) in adults and malignant glioma, including glioblastoma multiforme or anaplastic astrocytoma (a rare malignant brain tumour) in patients older than 3years.
Myzotem 250mg Capsule works by binding to the DNA (deoxyribonucleic acid-genetic material of the cell) and interfering with cell growth and division. Thus, Myzotem 250mg Capsule prevents tumours from growing.
Myzotem 250mg Capsule may cause permanent infertility. Male patients should use effective contraception and refrain from fathering a child for up to three months after treatment is completed. Prior to treatment, it is recommended to seek sperm conservation advice from your doctor.
Yes, Myzotem 250mg Capsule can cause neutropenia (low white blood cells count), lymphopenia (low lymphocytes count), thrombocytopenia (low platelet count). As a part of therapy, your doctor may monitor your blood profile.
Myzotem 250mg Capsule may lead to hyperglycemia (Increased blood sugar). Consult your doctor if you are diabetic. Regularly monitor your blood sugar levels while taking Myzotem 250mg Capsule.
The live vaccine may interact with Myzotem 250mg Capsule. Do not have vaccinations or immunisations without talking to your doctor first.

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