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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy
Glioz 250 mg Capsules is an anti-cancer medicine used in the treatment of brain tumours such as glioblastoma multiforme (a type of tumour that grows and spreads rapidly) in adults and malignant glioma, including glioblastoma multiforme or anaplastic astrocytoma. This medicine works by inhibiting the production of DNA (deoxyribonucleic acid-genetic material of the cell), thereby affecting cell growth and division. Common side effects include loss of appetite, anxiety, confusion, headache, vomiting, nausea, diarrhoea, constipation, muscle weakness, muscle aches, and fever.
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Composition :

TEMOZOLOMIDE-250MG

Manufacturer/Marketer :

Dr Reddy's Laboratories Ltd

Consume Type :

ORAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Glioz 250 mg Capsules

Glioz 250 mg Capsules belongs to a class of medicines called 'anti-cancer/ antitumor agent', used to treat specific forms of brain tumours such as glioblastoma multiforme (a type of tumour that grows and spreads rapidly) in adults and malignant glioma, including glioblastoma multiforme or anaplastic astrocytoma (a rare malignant brain tumour) in patients older than 3years. A brain tumour is an uncontrolled and unregulated proliferation of cells in the brain. 

Glioz 250 mg Capsules contains Temozolomide which works by inhibiting the production of DNA (deoxyribonucleic acid-genetic material of the cell), thereby affecting cell growth and division. Thus, Glioz 250 mg Capsules prevents tumours from growing.

Take Glioz 250 mg Capsules as prescribed. In some cases, Glioz 250 mg Capsules may cause loss of appetite, anxiety, confusion, headache, vomiting, nausea, diarrhoea, constipation, muscle weakness, muscle aches, and fever. Most of these side effects of Glioz 250 mg Capsules do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Let your doctor know if you are allergic to any of the contents. Glioz 250 mg Capsules is not recommended for patients with severe bone marrow depression or significant bleeding. Avoid taking Glioz 250 mg Capsules if you are pregnant or breastfeeding. Both women and men using Glioz 250 mg Capsules should use birth control to avoid pregnancy and fathering a child. It would be best not to drive and/or operate machines that require alertness as Glioz 250 mg Capsules may cause tiredness or sleepiness.

Uses of Glioz 250 mg Capsules

Treatment of Brain tumour

Directions for Use

Swallow it as a whole with water; do not crush, break or chew it.

Medicinal Benefits

Glioz 250 mg Capsules belongs to a class of medicines called anti-cancer/antitumor agents used to treat specific forms of brain tumours such as glioblastoma multiforme (a type of tumour that grows and spreads rapidly) in adults and malignant glioma, including glioblastoma multiforme or anaplastic astrocytoma (a rare malignant brain tumour) in patients older than 3years. It contains Temozolomide which works by binding to the DNA (deoxyribonucleic acid-genetic material of the cell) and interfering with cell growth and division. Thus, Glioz 250 mg Capsules prevents tumours from growing.

How Glioz 250 mg Capsules Works

Glioz 250 mg Capsules contains Temozolomide which works by inhibiting the production of DNA (deoxyribonucleic acid-genetic material of the cell), thereby affecting cell growth and division. Thus, Glioz 250 mg Capsules prevents tumours from growing.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Glioz 250 mg Capsules

  • Loss of appetite
  • Difficulty speaking
  • Headache
  • Vomiting
  • Nausea
  • Diarrhoea
  • Constipation
  • Rash
  • Hair loss
  • Tiredness
  • Infections
  • Fever
  • Increased blood sugar
  • Dry skin
  • Swelling
  • Weight loss/gain
  • Frequent urination

What if I have taken an overdose of Glioz 250 mg Capsules

Do not take more than the prescribed dose of Glioz 250 mg Capsules as it may cause overdose. The symptoms of overdose include unusual bleeding or bruising; red/black/tarry stools; red/dark brown/pink urine; coughing up or vomiting blood or material that looks like coffee grounds; sore throat, fever, ongoing congestion and cough, or other signs of infection. If you suspect you have taken overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

Glioz 250 mg Capsules should be taken under strict medical supervision. The doctor will regularly monitor your condition while taking Glioz 250 mg Capsules. To treat your condition effectually, continue taking Glioz 250 mg Capsules for as long as your doctor has prescribed. Do not stop Glioz 250 mg Capsules midway under any circumstances without consulting the healthcare professional. Inform your doctor if you have an allergy to any components of Glioz 250 mg Capsules. Inform your doctor before taking Glioz 250 mg Capsules if you have allergic reactions, infections, lung, renal or hepatic disorders or low blood count (including neutropenia, lymphopenia, thrombocytopenia). Glioz 250 mg Capsules is not recommended for patients with severe bone marrow depression or significant bleeding. Avoid taking Glioz 250 mg Capsules if you are pregnant or breastfeeding. Both women and men using Glioz 250 mg Capsules should use birth control to avoid pregnancy or fathering a child. Do not receive any vaccinations or immunizations without your doctor's approval while taking Glioz 250 mg Capsules.

Drug-Drug Interactions

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TemozolomideThalidomide
Severe
TemozolomideFingolimod
Severe

Drug-Drug Interactions

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TemozolomideThalidomide
Severe
How does the drug interact with Glioz 250 mg Capsules 5's:
Taking thalidomide with Glioz 250 mg Capsules 5's can increase the risk of blood clots.

How to manage the interaction:
Although taking Glioz 250 mg Capsules 5's and thalidomide together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as chest pain, shortness of breath, difficulty breathing, coughing up blood, sudden loss of vision, and/or pain, redness or swelling in an arm or leg. Do not stop using any medications without consulting doctor.
TemozolomideFingolimod
Severe
How does the drug interact with Glioz 250 mg Capsules 5's:
Taking Glioz 250 mg Capsules 5's with Fingolimod can increase the risk of infection.

How to manage the interaction:
Although taking Glioz 250 mg Capsules 5's and fingolimod together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without consulting doctor.
TemozolomideVoclosporin
Severe
How does the drug interact with Glioz 250 mg Capsules 5's:
Taking voclosporin with Glioz 250 mg Capsules 5's, may increase the risk of serious infections.

How to manage the interaction:
Although taking Glioz 250 mg Capsules 5's and voclosporin together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without consulting doctor.
TemozolomideInfliximab
Severe
How does the drug interact with Glioz 250 mg Capsules 5's:
Taking Glioz 250 mg Capsules 5's with Infliximab can increase the risk of infections.

How to manage the interaction:
Although taking Glioz 250 mg Capsules 5's and infliximab together can result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without consulting a doctor.
TemozolomideAdalimumab
Severe
How does the drug interact with Glioz 250 mg Capsules 5's:
Using adalimumab together with Glioz 250 mg Capsules 5's may increase the risk of serious infections.

How to manage the interaction:
Although taking Glioz 250 mg Capsules 5's and Adalimumab together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without first talking to your doctor.
TemozolomideCladribine
Severe
How does the drug interact with Glioz 250 mg Capsules 5's:
Using cladribine together with Glioz 250 mg Capsules 5's may increase the risk of serious infections.

How to manage the interaction:
Although taking Glioz 250 mg Capsules 5's and cladribine together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without consulting doctor.
TemozolomideLeflunomide
Severe
How does the drug interact with Glioz 250 mg Capsules 5's:
Taking Glioz 250 mg Capsules 5's with Leflunomide can increase the risk of infections.

How to manage the interaction:
Although taking Glioz 250 mg Capsules 5's and leflunomide together can result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, red or inflamed skin, body sores, pain or burning during urination, vomiting, dark-colored urine, light-colored stools, and/or yellowing of the skin or eyes. Do not stop using any medications without consulting a doctor.
TemozolomideBaricitinib
Severe
How does the drug interact with Glioz 250 mg Capsules 5's:
Taking baricitinib and Glioz 250 mg Capsules 5's can increase the risk of developing serious infections.

How to manage the interaction:
Although there is an interaction, baricitinib can be taken with Glioz 250 mg Capsules 5's if prescribed by the doctor. However, if you experience fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in your coughing fluid, red or irritated skin, body sores, and discomfort or burning when you urinate, consult a doctor. Do not stop using any medications without talking to a doctor.
TemozolomideClozapine
Severe
How does the drug interact with Glioz 250 mg Capsules 5's:
Taking Glioz 250 mg Capsules 5's with clozapine may increase the risk of serious infections.

How to manage the interaction:
Although taking Glioz 250 mg Capsules 5's and clozapine together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without consulting doctor.
TemozolomideEtanercept
Severe
How does the drug interact with Glioz 250 mg Capsules 5's:
Taking Glioz 250 mg Capsules 5's with Etanercept can increase the risk of infections.

How to manage the interaction:
Although taking Glioz 250 mg Capsules 5's and etanercept together can result in an interaction, it can be taken if a doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without consulting doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • De-stress yourself by meditating, reading books, taking a warm bubble bath or listening to soothing music.
  • Performing yoga may also help in improving both physical and mental health.
  • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
  • Eat a healthy diet and exercise regularly to maintain proper weight.
  • Include leafy vegetables, citrus fruits, fatty fish, berries, yoghurt, apples, peaches, cauliflower, cabbage, broccoli, beans, and herbs in your diet.
  • Get optimal sleep; rest well.
  • Avoid smoking and alcohol consumption.
  • Avoid fast food, fried food, processed meats, refined carbs and added sugars.

Habit Forming

No

Therapeutic Class

ANTINEOPLASTIC

Glioz 250 mg Capsules Substitute

Substitutes safety advice
  • Temoside 250 Capsule 5's

    1173.58per tablet
  • Gliotem 250 Capsule 1's

    3952.40per tablet
  • Gliotem 250 mg Capsule 10's

    352.52per tablet
  • Temonat 250mg 5 Capsule

    18860.00per tablet
  • TEMOLON 250MG CAPSULE

    3952.56per tablet
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Alcohol

Caution

You are recommended to avoid alcohol consumption while taking Glioz 250 mg Capsules. It could lead to unpleasant side effects.

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Pregnancy

Caution

Please consult your doctor if you have any concerns about this. Glioz 250 mg Capsules should not be used during pregnancy unless prescribed by your doctor. Women of childbearing potential must use effective contraception during the treatment and for 6months after completion of the treatment.

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Breast Feeding

Unsafe

Glioz 250 mg Capsules should not be taken during breastfeeding as it passes into the breastmilk and may harm the baby.

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Driving

Caution

Glioz 250 mg Capsules may make you feel tired or sleepy. Drive and/or operate machines only if you are alert.

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Liver

Caution

If you have had a history or evidence of any liver-related diseases, please consult the doctor before using Glioz 250 mg Capsules. Your doctor will weigh the benefits and potential risks before prescribing Glioz 250 mg Capsules.

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Kidney

Caution

If you have had a history or evidence of any kidney-related diseases, please consult the doctor before using Glioz 250 mg Capsules. Your doctor will weigh the benefits and potential risks before prescribing Glioz 250 mg Capsules.

bannner image

Children

Caution

Safety and effectiveness of Glioz 250 mg Capsules in paediatric patients under the age of three have not been established.

FAQs

Glioz 250 mg Capsules belongs to a class of medicines called anti-cancer agents, used to treat specific forms of brain tumours such as glioblastoma multiforme (a type of tumour that grows and spreads rapidly) in adults and malignant glioma, including glioblastoma multiforme or anaplastic astrocytoma (a rare malignant brain tumour) in patients older than 3years.
Glioz 250 mg Capsules works by binding to the DNA (deoxyribonucleic acid-genetic material of the cell) and interfering with cell growth and division. Thus, Glioz 250 mg Capsules prevents tumours from growing.
Glioz 250 mg Capsules may cause permanent infertility. Male patients should use effective contraception and refrain from fathering a child for up to three months after treatment is completed. Prior to treatment, it is recommended to seek sperm conservation advice from your doctor.
Yes, Glioz 250 mg Capsules can cause neutropenia (low white blood cells count), lymphopenia (low lymphocytes count), thrombocytopenia (low platelet count). As a part of therapy, your doctor may monitor your blood profile.
Glioz 250 mg Capsules may lead to hyperglycemia (Increased blood sugar). Consult your doctor if you are diabetic. Regularly monitor your blood sugar levels while taking Glioz 250 mg Capsules.
The live vaccine may interact with Glioz 250 mg Capsules. Do not have vaccinations or immunisations without talking to your doctor first.

Country of origin

India

Manufacturer/Marketer address

Dr. Reddy's Laboratories Ltd., 8-2-337, Road No. 3, Banjara Hills, Hyderabad, Telangana 500034, INDIA
Other Info - GLI0237

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