Gliotem 250 Capsule belongs to a class of medicines called 'anti-cancer/ antitumor agent', used to treat specific forms of brain tumours such as glioblastoma multiforme (a type of tumour that grows and spreads rapidly) in adults and malignant glioma, including glioblastoma multiforme or anaplastic astrocytoma (a rare malignant brain tumour) in patients older than 3years. A brain tumour is an uncontrolled and unregulated proliferation of cells in the brain. 

Gliotem 250 Capsule contains Temozolomide which works by inhibiting the production of DNA (deoxyribonucleic acid-genetic material of the cell), thereby affecting cell growth and division. Thus, Gliotem 250 Capsule prevents tumours from growing.

Take Gliotem 250 Capsule as prescribed. In some cases, Gliotem 250 Capsule may cause loss of appetite, anxiety, confusion, headache, vomiting, nausea, diarrhoea, constipation, muscle weakness, muscle aches, and fever. Most of these side effects of Gliotem 250 Capsule do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Let your doctor know if you are allergic to any of the contents. Gliotem 250 Capsule is not recommended for patients with severe bone marrow depression or significant bleeding. Avoid taking Gliotem 250 Capsule if you are pregnant or breastfeeding. Both women and men using Gliotem 250 Capsule should use birth control to avoid pregnancy and fathering a child. It would be best not to drive and/or operate machines that require alertness as Gliotem 250 Capsule may cause tiredness or sleepiness.

Gliotem 250 Capsule belongs to a class of medicines called anti-cancer/antitumor agents used to treat specific forms of brain tumours such as glioblastoma multiforme (a type of tumour that grows and spreads rapidly) in adults and malignant glioma, including glioblastoma multiforme or anaplastic astrocytoma (a rare malignant brain tumour) in patients older than 3years. It contains Temozolomide which works by binding to the DNA (deoxyribonucleic acid-genetic material of the cell) and interfering with cell growth and division. Thus, Gliotem 250 Capsule prevents tumours from growing.

• Loss of appetite
• Difficulty speaking
• Headache
• Vomiting
• Nausea
• Diarrhoea
• Constipation
• Rash
• Hair loss
• Tiredness
• Infections
• Fever
• Increased blood sugar
• Dry skin
• Swelling
• Weight loss/gain
• Frequent urination

Gliotem 250 Capsule should be taken under strict medical supervision. The doctor will regularly monitor your condition while taking Gliotem 250 Capsule. To treat your condition effectually, continue taking Gliotem 250 Capsule for as long as your doctor has prescribed. Do not stop Gliotem 250 Capsule midway under any circumstances without consulting the healthcare professional. Inform your doctor if you have an allergy to any components of Gliotem 250 Capsule. Inform your doctor before taking Gliotem 250 Capsule if you have allergic reactions, infections, lung, renal or hepatic disorders or low blood count (including neutropenia, lymphopenia, thrombocytopenia). Gliotem 250 Capsule is not recommended for patients with severe bone marrow depression or significant bleeding. Avoid taking Gliotem 250 Capsule if you are pregnant or breastfeeding. Both women and men using Gliotem 250 Capsule should use birth control to avoid pregnancy or fathering a child. Do not receive any vaccinations or immunizations without your doctor's approval while taking Gliotem 250 Capsule.

Drug-Drug Interactions: Gliotem 250 Capsule interacts with medicines used to treat infections (e.g. adalimumab), medicines used to treat rheumatoid arthritis (e.g. baricitinib, certolizumab, golimumab, infliximab, leflunomide, upadacitinib), medicines used to treat certain cancers (e.g. cladribine), medicines used to treat mental/mood disorders (e.g. clozapine), medicines used to treat multiple sclerosis (e.g. fingolimod, siponimod, teriflunomide),  cholesterol-lowering medications (e.g. lomitapide), and vaccines (e.g. BCG vaccine, influenza virus vaccine, measles virus vaccine, rotavirus vaccine, rubella virus vaccine smallpox vaccine, typhoid vaccine, varicella virus vaccine, yellow fever vaccine, zoster vaccine).

Drug-Food Interactions: Avoid the consumption of alcohol while taking Gliotem 250 Capsule.

Drug-Disease Interactions: Inform your doctor before taking the Gliotem 250 Capsule you are suffering from urticaria or allergic reactions, bleeding disorders, myelosuppression (bone marrow depression), low blood counts, hepatic or renal dysfunction or disorders.

• ADALIMUMAB
• BARICITINIB
• CERTOLIZUMAB
• GOLIMUMAB
• INFLIXIMAB
• LEFLUNOMIDE
• UPADACITINIB
• CLADRIBINE
• CLOZAPINE
• FINGOLIMOD
• SIPONIMOD
• TERIFLUNOMIDE
• LOMITAPIDE
• BCG VACCINE
• INFLUENZA (LIVE ATTENUATED)
• MEASLES (LIVE ATTENUATED)
• ROTAVIRUS VACCINE
• RUBELLA (LIVE ATTENUATED)
• SMALLPOX VACCINE
• TYPHOID VACCINE
• VARICELLA (LIVE ATTENUATED)
• YELLOW FEVER VACCINE
• ZOSTER VACCINE LIVE

• De-stress yourself by meditating, reading books, taking a warm bubble bath or listening to soothing music.
• Performing yoga may also help in improving both physical and mental health.
• Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
• Eat a healthy diet and exercise regularly to maintain proper weight.
• Include leafy vegetables, citrus fruits, fatty fish, berries, yoghurt, apples, peaches, cauliflower, cabbage, broccoli, beans, and herbs in your diet.
• Get optimal sleep; rest well.
• Avoid smoking and alcohol consumption.
• Avoid fast food, fried food, processed meats, refined carbs and added sugars.

• Gliotem 250 Capsule should be taken under strict medical supervision. The doctor will regularly monitor your condition while taking Gliotem 250 Capsule.
• Your doctor may advise you to get routine blood tests done to monitor your liver function, electrolyte levels, and blood cell count.
• Both male and female patients who are taking Gliotem 250 Capsule must use effective contraceptive precautions. Women of childbearing potential must use effective contraception during the treatment and for 6months after completion of the treatment. Male patients should avoid fathering a child while on treatment with Gliotem 250 Capsule and should use effective contraception during the treatment and for 3months after the treatment.

Brain tumour: A brain tumour is an uncontrolled, unregulated proliferation of cells in the brain. The cancerous cells can invade and destroy surrounding healthy tissue, including organs. The symptoms of a brain tumour differ depending on the tumour's location in the brain. Common symptoms include headaches, fits (seizures), feeling unwell or being sick all the time, behavioural changes, paralysis, sickness, eyesight or speech impairments.