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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Lenangio 10 Capsule is used to treat cancers such as multiple myeloma, myelodysplastic syndromes, mantle cell lymphoma, and follicular lymphoma. It contains lenalidomide, which works by stimulating the immune system to attack the cancer cells. It also kills the abnormal cells in the bone marrow and helps the bone marrow to produce normal blood cells. In some cases, this medicine may cause side effects, such as fatigue, constipation, diarrhoea, and weakness. Before taking this medicine, inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.
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Composition :

LENALIDOMIDE-10MG

Manufacturer/Marketer :

Dr Reddy's Laboratories Ltd

Consume Type :

ORAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Lenangio 10 Capsule

Lenangio 10 Capsule is used to treat multiple myeloma, myelodysplastic syndromes, mantle cell lymphoma, and follicular lymphoma. Lenangio 10 Capsule is used to treat a type of myelodysplastic syndromes (MDS) known as deletion 5q MDS, where part of chromosome 5 is missing.
 
Lenangio 10 Capsule contains ‘lenalidomide’, which works by helping the body’s immune system and directly attacks cancer. It stops the development of cancer cells, stops the blood vessels growing in cancer, and stimulates the part of the immune system to attack the cancer cells. Lenangio 10 Capsule kills the abnormal cells in the bone marrow and helps the bone marrow to produce normal blood cells.
 
You are advised to take Lenangio 10 Capsule for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain common side effects, such as fatigue, constipation, diarrhoea, muscle cramps, nausea, headache, upper respiratory tract infection, dizziness, shortness of breath, and weakness. Talk with your doctor if you experience any of these side effects persistently.
 
Avoid taking Lenangio 10 Capsule if you are pregnant or breastfeeding. Lenangio 10 Capsule may cause dizziness, sleepiness, tiredness, and blurred vision, so drive only if you are alert. Lenangio 10 Capsule is not recommended for children below 18 years as safety and effectiveness have not been established. Men and women taking Lenangio 10 Capsule must use effective contraception. Inform your doctor regarding your health condition and medications before taking Lenangio 10 Capsule to rule out any interactions.

Uses of Lenangio 10 Capsule

Treatment of Multiple myeloma, myelodysplastic syndromes, mantle cell lymphoma, and follicular lymphoma.

Directions for Use

Swallow Lenangio 10 Capsule as a whole with water; do not crush or chew it.

Medicinal Benefits

Lenangio 10 Capsule belongs to the group of medicines called immunomodulatory agents. Lenangio 10 Capsule is used to treat multiple myeloma, myelodysplastic syndromes, mantle cell lymphoma, and follicular lymphoma. Lenangio 10 Capsule works by helping the body’s immune system and directly attacks cancer. It stops the development of cancer cells, stops the blood vessels growing in cancer, and stimulates the part of the immune system to attack the cancer cells. Lenangio 10 Capsule kills the abnormal cells in the bone marrow and helps the bone marrow to produce normal blood cells. Lenangio 10 Capsule is used to treat a type of myelodysplastic syndromes (MDS) known as deletion 5q MDS, where part of chromosome 5 is missing.

How Lenangio 10 Capsule Works

Lenangio 10 Capsule contains ‘lenalidomide’, which works by helping the body’s immune system and directly attacks cancer. It stops the development of cancer cells, stops the blood vessels growing in cancer, and stimulates the part of the immune system to attack the cancer cells. Lenangio 10 Capsule kills the abnormal cells in the bone marrow and helps the bone marrow to produce normal blood cells.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Lenangio 10 Capsule

  • Weakness
  • Constipation
  • Diarrhoea
  • Nausea
  • Vomiting
  • Stomach pain
  • Heartburn
  • Shortness of breath
  • Headache
  • Muscle/bone/back pain
  • Decrease in red blood cell count
  • Fever and flu-like symptoms
  • Decreased appetite
  • Blurred vision
  • Upper respiratory tract infection
  • Dry mouth

What if I have taken an overdose of Lenangio 10 Capsule

Take Lenangio 10 Capsule only as prescribed by the physician. Do not exceed the recommended dose, as it might cause an overdose. If you suspect you have taken an overdose, seek immediate medical attention.

Drug Warnings

Do not take Lenangio 10 Capsule if you are allergic to any of its components. Inform your doctor if you have/had blood clots, heart attack, neuropathy, slow heart rate, high blood pressure, low blood pressure, high cholesterol levels, infections/signs of infections, viral infection, HIV, hepatitis B, epilepsy, liver or kidney problems. Do not take Lenangio 10 Capsule if you are pregnant, as it might cause severe birth defects or the death of the unborn baby. Avoid taking Lenangio 10 Capsule if you are breastfeeding as it is not unknown if it passes into breastmilk. Lenangio 10 Capsule may cause dizziness, sleepiness and blurred vision, so drive only if you are alert. Lenangio 10 Capsule is not recommended for use in children. Avoid consuming alcohol along with Lenangio 10 Capsule as it could lead to increased dizziness and sleepiness. Let your doctor know regarding your health condition and medications you are taking, including over the counter and herbal products.

Drug-Drug Interactions

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LenalidomideAnakinra
Critical
LenalidomideYellow fever vaccine
Critical

Drug-Drug Interactions

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LenalidomideAnakinra
Critical
How does the drug interact with Lenangio 10 Capsule 10's:
Taking anakinra with Lenangio 10 Capsule 10's can increase the risk of negative side effects.

How to manage the interaction:
Taking Lenangio 10 Capsule 10's with Anakinra is not recommended, but it can be taken if advised by your doctor. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
LenalidomideYellow fever vaccine
Critical
How does the drug interact with Lenangio 10 Capsule 10's:
When combining the Yellow fever vaccine with Lenangio 10 Capsule 10's, there's an increased risk of vaccine-related infections or a diminished vaccine response.

How to manage the interaction:
Taking Lenangio 10 Capsule 10's with Yellow fever vaccine is not recommended, but it can be taken if prescribed by a doctor. However, contact a doctor if you experience any symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, discomfort, or burning during urination. Do not stop taking any medications without consulting a doctor.
LenalidomideBCG vaccine
Critical
How does the drug interact with Lenangio 10 Capsule 10's:
Combining the BCG vaccine with Lenangio 10 Capsule 10's increases the risk of vaccine-related infections or a diminished vaccine response.

How to manage the interaction:
Taking Lenangio 10 Capsule 10's with BCG vaccine is not recommended, but it can be taken if prescribed by a doctor. However, contact a doctor if you experience any symptoms of infection, such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, discomfort, or burning during urination. Do not stop taking any medications without consulting a doctor.
LenalidomideRotavirus vaccine
Critical
How does the drug interact with Lenangio 10 Capsule 10's:
Administering the Rotavirus vaccine together with Lenangio 10 Capsule 10's may increase the risk of infections.

How to manage the interaction:
Taking Lenangio 10 Capsule 10's with the Rotavirus vaccine is not recommended, but it can be taken if prescribed by a doctor. It is recommended to take the rotavirus vaccine a few weeks after the treatment with Lenangio 10 Capsule 10's. Do not stop using any medications without consulting a doctor.
LenalidomideFilgrastim
Severe
How does the drug interact with Lenangio 10 Capsule 10's:
Using filgrastim together with Lenangio 10 Capsule 10's can reduce the effect of filgrastim.

How to manage the interaction:
Co-administration of Filgrastim with Lenangio 10 Capsule 10's can possibly result in an interaction, but it can be taken if your doctor has advised it. Do not discontinue any medications without consulting a doctor.
LenalidomideLomitapide
Severe
How does the drug interact with Lenangio 10 Capsule 10's:
Lenangio 10 Capsule 10's can cause liver problems, and combining it with other drugs, such as Lomitapide, can raise the risk.

How to manage the interaction:
There may be a possibility of interaction between Lenangio 10 Capsule 10's and Lomitapide, but it can be taken if prescribed by a doctor. If you have any of these symptoms: fever, chills, joint pain, swelling, bruising, skin rash, itching, bleeding, feeling tired, feeling sick, stomach ache, dark urine, or liver problems, contact your doctor immediately. Do not stop using any medications without talking to your doctor.
LenalidomideDiethylstilbestrol
Severe
How does the drug interact with Lenangio 10 Capsule 10's:
Taking Lenangio 10 Capsule 10's together with diethylstilbestrol may increase the risk of blood clots.

How to manage the interaction:
Although there is an interaction between Lenangio 10 Capsule 10's and diethylstilbestrol, it can be taken if your doctor has advised it. However, if you experience chest pain, shortness of breath, difficulty breathing, coughing up blood, sudden loss of vision, pain, redness or swelling in an arm or leg, and numbness or weakness on one side of the body, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
LenalidomideFluvastatin
Severe
How does the drug interact with Lenangio 10 Capsule 10's:
Coadministration of fluvastatin and Lenangio 10 Capsule 10's together may increase the risk of a condition called rhabdomyolysis (the breakdown of skeletal muscle).

How to manage the interaction:
Although there is an interaction between Lenangio 10 Capsule 10's and fluvastatin, it can be taken if your doctor has advised it. However, if you experience unexplained muscle pain, tenderness, or weakness, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
LenalidomideOspemifene
Severe
How does the drug interact with Lenangio 10 Capsule 10's:
Coadministration of Lenangio 10 Capsule 10's and ospemifene may increase the risk of blood clots.

How to manage the interaction:
Although there is an interaction between Lenangio 10 Capsule 10's and ospemifene, it can be taken if prescribed by a doctor. However, if you experience chest pain, shortness of breath, difficulty breathing, coughing up blood, sudden loss of vision, pain, redness or swelling in an arm or leg, and numbness or weakness on one side of the body, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
LenalidomideLeflunomide
Severe
How does the drug interact with Lenangio 10 Capsule 10's:
Combining Lenangio 10 Capsule 10's with Leflunomide can increase the risk and severity of side effects.

How to manage the interaction:
Although taking Lenangio 10 Capsule 10's and Leflunomide together can evidently cause an interaction, it can be taken if your doctor has suggested it. If you have any of these symptoms, contact your doctor right away. These symptoms include infection, liver problems, fever, chills, diarrhea, sore throat, muscle pain, difficulty breathing, weight loss, pain, joint pain, swelling, bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark urine, or bleeding. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat a healthy diet and exercise regularly to maintain proper weight.

  • Avoid smoking and alcohol consumption.

  • Include food rich in iron, such as lean red meat, raisins, bell peppers, Brussel sprouts, and broccoli.

  • To prevent constipation, consume fibre-rich foods such as whole grains, broccoli, dried fruits, nuts, beans, apples, oranges, and pears. 

Habit Forming

No

Therapeutic Class

IMMUNOMODULATORS

Lenangio 10 Capsule Substitute

Substitutes safety advice
  • Lenalid 10 Capsule 30's

    123.44per tablet
  • Laviat 10 mg Capsule 10's

    132.57per tablet
  • Lenmid 10 Capsule 10's

    53.30per tablet
  • Myelosafe Capsule 10's

    by AYUR

    11.52per tablet
  • Kabilen 10 mg Tablet 1's

    281.84per tablet
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Alcohol

Unsafe

You are recommended to avoid alcohol consumption while taking Lenangio 10 Capsule as it might cause increased dizziness.

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Pregnancy

Unsafe

Lenangio 10 Capsule should not be taken during pregnancy as it causes severe birth defects or death to an unborn baby. Use highly effective contraception if you are a woman of child-bearing age. Inform your doctor if you are pregnant, think you are pregnant or planning for pregnancy.

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Breast Feeding

Unsafe

Avoid breastfeeding while taking Lenangio 10 Capsule as it is unknown if Lenangio 10 Capsule passes into breastmilk.

bannner image

Driving

Unsafe

Lenangio 10 Capsule may cause dizziness, sleepiness, and blurred vision. Do not drive or operate heavy machinery unless you are alert.

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Liver

Caution

Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Dose adjustment may be necessary. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Unsafe

Lenangio 10 Capsule is not recommended for children below 18years as the safety and effectiveness have not been established.

FAQs

Lenangio 10 Capsule is used to treat multiple myeloma, myelodysplastic syndromes, mantle cell lymphoma, and follicular lymphoma. It is also used to treat a type of myelodysplastic syndrome (MDS) known as deletion 5q MDS, where part of chromosome 5 is missing.
Lenangio 10 Capsule works by helping the body’s immune system and directly attacks cancer. It stops the development of cancer cells, stops the blood vessels growing in cancer, and stimulates the part of the immune system to attack the cancer cells.
Do not stop taking Lenangio 10 Capsule on your own. You are advised to take Lenangio 10 Capsule for as long as your doctor has prescribed it for you, depending on your medical condition. Do not be reluctant to speak with your doctor if you experience any difficulty while taking Lenangio 10 Capsule .
No, it is not safe to father a child while taking Lenangio 10 Capsule . Lenangio 10 Capsule can pass into human semen. During sexual activity with females of reproductive potential, always use effective contraception such as latex or synthetic condom while taking Lenangio 10 Capsule and for at least 4weeks after discontinuing Lenangio 10 Capsule , even if you have undergone a successful vasectomy. Male patients taking Lenangio 10 Capsule must not donate semen whilst taking Lenangio 10 Capsule and for 4weeks after discontinuing Lenangio 10 Capsule .
Patients taking Lenangio 10 Capsule must not donate blood during the treatment with Lenangio 10 Capsule and for 1month after discontinuation of Lenangio 10 Capsule as the donated blood might be given to pregnant women whose foetus should not be exposed to Lenangio 10 Capsule since it causes severe birth defects.
People with multiple myeloma taking Lenangio 10 Capsule may have an increased risk for blood clots in veins, arteries, and lungs. The risk is even higher if you are taking dexamethasone with Lenangio 10 Capsule for treating multiple myeloma. Consult your doctor immediately if you notice symptoms such as shortness of breath, chest pain, and swelling in the legs or arm.
Lenangio 10 Capsule might cause neutropenia (low white blood cells) or thrombocytopenia (low platelets). Blood count should be checked regularly during treatment with Lenangio 10 Capsule .
You should take Lenangio 10 Capsule at the same time every day. You can take the capsules with or without food.
Dose adjustment may be necessary. Please consult your doctor if you have kidney impairment or any concerns regarding this.
Some people treated with Lenangio 10 Capsule may rarely get other cancers. Consult your doctor for more details.
Yes, you will need to get regular blood tests while taking Lenangio 10 Capsule . Your doctor may suggest taking tests before and during treatment.
Yes, even women with fertility difficulties must take birth control while taking this medication. You must also take a negative pregnancy test 10 to 14 days before treatment and again 24 hours before. You will be tested for pregnancy every 2 to 4 weeks while on Lenangio 10 Capsule .
Lenangio 10 Capsule contains Lenalidomide as an active ingredient.
Common side effects of Lenangio 10 Capsule may include fatigue, constipation, diarrhoea, muscle cramps, nausea, headache, upper respiratory tract infection, dizziness, shortness of breath, and weakness. Talk with your doctor if you persistently experience any of these side effects.
Lenangio 10 Capsule should not be taken during pregnancy as it causes severe birth defects or death to an unborn baby. Use highly effective contraception if you are a woman of childbearing age. Inform your doctor if you are pregnant, think you are pregnant or planning for pregnancy.
Avoid breastfeeding while taking Lenangio 10 Capsule as it is unknown if Lenangio 10 Capsule passes into breastmilk.

Country of origin

India

Manufacturer/Marketer address

Dr. Reddy's Laboratories Ltd., 8-2-337, Road No. 3, Banjara Hills, Hyderabad, Telangana 500034, INDIA
Other Info - LEN0010

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