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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Lenakast-10 Capsule 30's is used to treat cancers such as multiple myeloma, myelodysplastic syndromes, mantle cell lymphoma, and follicular lymphoma. It contains lenalidomide, which works by stimulating the immune system to attack the cancer cells. It also kills the abnormal cells in the bone marrow and helps the bone marrow to produce normal blood cells. In some cases, this medicine may cause side effects, such as fatigue, constipation, diarrhoea, and weakness. Before taking this medicine, inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.
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Whats That

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Composition :

LENALIDOMIDE-10MG

Manufacturer/Marketer :

Aprazer Healthcare Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

About Lenakast-10 Capsule 30's

Lenakast-10 Capsule 30's is used to treat multiple myeloma, myelodysplastic syndromes, mantle cell lymphoma, and follicular lymphoma. Lenakast-10 Capsule 30's is used to treat a type of myelodysplastic syndromes (MDS) known as deletion 5q MDS, where part of chromosome 5 is missing.
 
Lenakast-10 Capsule 30's contains ‘lenalidomide’, which works by helping the body’s immune system and directly attacks cancer. It stops the development of cancer cells, stops the blood vessels growing in cancer, and stimulates the part of the immune system to attack the cancer cells. Lenakast-10 Capsule 30's kills the abnormal cells in the bone marrow and helps the bone marrow to produce normal blood cells.
 
You are advised to take Lenakast-10 Capsule 30's for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain common side effects, such as fatigue, constipation, diarrhoea, muscle cramps, nausea, headache, upper respiratory tract infection, dizziness, shortness of breath, and weakness. Talk with your doctor if you experience any of these side effects persistently.
 
Avoid taking Lenakast-10 Capsule 30's if you are pregnant or breastfeeding. Lenakast-10 Capsule 30's may cause dizziness, sleepiness, tiredness, and blurred vision, so drive only if you are alert. Lenakast-10 Capsule 30's is not recommended for children below 18 years as safety and effectiveness have not been established. Men and women taking Lenakast-10 Capsule 30's must use effective contraception. Inform your doctor regarding your health condition and medications before taking Lenakast-10 Capsule 30's to rule out any interactions.

Uses of Lenakast-10 Capsule 30's

Treatment of Multiple myeloma, myelodysplastic syndromes, mantle cell lymphoma, and follicular lymphoma.

Directions for Use

Swallow Lenakast-10 Capsule 30's as a whole with water; do not crush or chew it.

Medicinal Benefits

Lenakast-10 Capsule 30's belongs to the group of medicines called immunomodulatory agents. Lenakast-10 Capsule 30's is used to treat multiple myeloma, myelodysplastic syndromes, mantle cell lymphoma, and follicular lymphoma. Lenakast-10 Capsule 30's works by helping the body’s immune system and directly attacks cancer. It stops the development of cancer cells, stops the blood vessels growing in cancer, and stimulates the part of the immune system to attack the cancer cells. Lenakast-10 Capsule 30's kills the abnormal cells in the bone marrow and helps the bone marrow to produce normal blood cells. Lenakast-10 Capsule 30's is used to treat a type of myelodysplastic syndromes (MDS) known as deletion 5q MDS, where part of chromosome 5 is missing.

How Lenakast-10 Capsule 30's Works

Lenakast-10 Capsule 30's contains ‘lenalidomide’, which works by helping the body’s immune system and directly attacks cancer. It stops the development of cancer cells, stops the blood vessels growing in cancer, and stimulates the part of the immune system to attack the cancer cells. Lenakast-10 Capsule 30's kills the abnormal cells in the bone marrow and helps the bone marrow to produce normal blood cells.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Lenakast-10 Capsule 30's

  • Weakness
  • Constipation
  • Diarrhoea
  • Nausea
  • Vomiting
  • Stomach pain
  • Heartburn
  • Shortness of breath
  • Headache
  • Muscle/bone/back pain
  • Decrease in red blood cell count
  • Fever and flu-like symptoms
  • Decreased appetite
  • Blurred vision
  • Upper respiratory tract infection
  • Dry mouth

What if I have taken an overdose of Lenakast-10 Capsule 30's

Take Lenakast-10 Capsule 30's only as prescribed by the physician. Do not exceed the recommended dose, as it might cause an overdose. If you suspect you have taken an overdose, seek immediate medical attention.

Drug Warnings

Do not take Lenakast-10 Capsule 30's if you are allergic to any of its components. Inform your doctor if you have/had blood clots, heart attack, neuropathy, slow heart rate, high blood pressure, low blood pressure, high cholesterol levels, infections/signs of infections, viral infection, HIV, hepatitis B, epilepsy, liver or kidney problems. Do not take Lenakast-10 Capsule 30's if you are pregnant, as it might cause severe birth defects or the death of the unborn baby. Avoid taking Lenakast-10 Capsule 30's if you are breastfeeding as it is not unknown if it passes into breastmilk. Lenakast-10 Capsule 30's may cause dizziness, sleepiness and blurred vision, so drive only if you are alert. Lenakast-10 Capsule 30's is not recommended for use in children. Avoid consuming alcohol along with Lenakast-10 Capsule 30's as it could lead to increased dizziness and sleepiness. Let your doctor know regarding your health condition and medications you are taking, including over the counter and herbal products.

Drug-Drug Interactions

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LenalidomideAnakinra
Critical
LenalidomideBCG vaccine
Critical

Drug-Drug Interactions

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LenalidomideAnakinra
Critical
How does the drug interact with Lenakast-10 Capsule:
Taking anakinra with Lenakast-10 Capsule can increase the risk of negative side effects.

How to manage the interaction:
Taking Lenakast-10 Capsule with Anakinra is not recommended, but it can be taken if advised by your doctor. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
LenalidomideBCG vaccine
Critical
How does the drug interact with Lenakast-10 Capsule:
Combining the BCG vaccine with Lenakast-10 Capsule increases the risk of vaccine-related infections or a diminished vaccine response.

How to manage the interaction:
Taking Lenakast-10 Capsule with BCG vaccine is not recommended, but it can be taken if prescribed by a doctor. However, contact a doctor if you experience any symptoms of infection, such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, discomfort, or burning during urination. Do not stop taking any medications without consulting a doctor.
LenalidomideRotavirus vaccine
Critical
How does the drug interact with Lenakast-10 Capsule:
Administering the Rotavirus vaccine together with Lenakast-10 Capsule may increase the risk of infections.

How to manage the interaction:
Taking Lenakast-10 Capsule with the Rotavirus vaccine is not recommended, but it can be taken if prescribed by a doctor. It is recommended to take the rotavirus vaccine a few weeks after the treatment with Lenakast-10 Capsule. Do not stop using any medications without consulting a doctor.
LenalidomideYellow fever vaccine
Critical
How does the drug interact with Lenakast-10 Capsule:
When combining the Yellow fever vaccine with Lenakast-10 Capsule, there's an increased risk of vaccine-related infections or a diminished vaccine response.

How to manage the interaction:
Taking Lenakast-10 Capsule with Yellow fever vaccine is not recommended, but it can be taken if prescribed by a doctor. However, contact a doctor if you experience any symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, discomfort, or burning during urination. Do not stop taking any medications without consulting a doctor.
LenalidomideLovastatin
Severe
How does the drug interact with Lenakast-10 Capsule:
The combination of lovastatin and Lenakast-10 Capsule may raise the risk of rhabdomyolysis, an uncommon but dangerous illness defined as the breakdown of skeletal muscle tissue.

How to manage the interaction:
There may be a possibility of interaction between Lenakast-10 Capsule and Lovastatin, but it can be taken if prescribed by a doctor. If you notice muscle weakness, pain, tenderness, or dark-coloured urine, contact your doctor immediately. These symptoms could be a sign of a condition called rhabdomyolysis, which can potentially harm your kidneys, especially if you already have kidney problems. Do not stop using any medications without talking to your doctor.
LenalidomideEstradiol
Severe
How does the drug interact with Lenakast-10 Capsule:
Coadministration of Estradiol and Lenakast-10 Capsule can increase the risk of blood clots.

How to manage the interaction:
Although there is an interaction between Lenakast-10 Capsule and estradiol, it can be taken if your doctor has advised it. However, if you experience chest pain, shortness of breath, difficulty breathing, coughing up blood, sudden loss of vision, pain, redness or swelling in an arm or leg, and numbness or weakness on one side of the body, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
LenalidomideConjugated Estrogens
Severe
How does the drug interact with Lenakast-10 Capsule:
Coadministration of Lenakast-10 Capsule with Conjugated estrogens may increase the risk of developing unwanted blood clots.

How to manage the interaction:
Although there is an interaction between Lenakast-10 Capsule and conjugated estrogens, it can be taken if prescribed by a doctor. However, if you experience chest pain, shortness of breath, coughing up blood, blurred vision, swelling in an arm or leg, and weakness, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
LenalidomideDarbepoetin alfa
Severe
How does the drug interact with Lenakast-10 Capsule:
Taking Darbepoetin alfa with Lenakast-10 Capsule can increase the risk of blood clots.

How to manage the interaction:
Although there is an interaction between Lenakast-10 Capsule and darbepoetin alfa, it can be taken if your doctor has advised it. However, if you experience chest pain, shortness of breath, difficulty breathing, coughing up blood, sudden loss of vision, pain, redness or swelling in an arm or leg, and numbness or weakness on one side of the body, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
LenalidomideVedolizumab
Severe
How does the drug interact with Lenakast-10 Capsule:
Combining Lenakast-10 Capsule with Vedolizumab can increase the chances of experiencing harmful side effects.

How to manage the interaction:
Taking Lenakast-10 Capsule with Vedolizumab together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, contact a doctor if you experience any symptoms of infection, such as chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, discomfort, or burning during urination. Do not stop using any medications without first talking to your doctor.
LenalidomidePitavastatin
Severe
How does the drug interact with Lenakast-10 Capsule:
Taking Lenakast-10 Capsule and Pitavastatin together can increase the risk of rhabdomyolysis (the breakdown of skeletal muscle tissue).

How to manage the interaction:
Although there is an interaction between Lenakast-10 Capsule and pitavastatin, it can be taken if prescribed by a doctor. However, if you experience unexplained muscle pain, tenderness, or weakness, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat a healthy diet and exercise regularly to maintain proper weight.

  • Avoid smoking and alcohol consumption.

  • Include food rich in iron, such as lean red meat, raisins, bell peppers, Brussel sprouts, and broccoli.

  • To prevent constipation, consume fibre-rich foods such as whole grains, broccoli, dried fruits, nuts, beans, apples, oranges, and pears. 

Habit Forming

No

Therapeutic Class

IMMUNOMODULATORS

Lenakast-10 Capsule 30's Substitute

Substitutes safety advice
  • Lenangio 10 Capsule 10's

    by Others

    100.26per tablet
  • Lenalid 10 Capsule 30's

    by Others

    123.44per tablet
  • Laviat 10 mg Capsule 10's

    by Others

    132.57per tablet
  • Braunamide 10 mg Capsule 10's

    by Others

    170.00per tablet
  • Celomide 10 Capsule

    by Others

    153.00per tablet
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Alcohol

Unsafe

You are recommended to avoid alcohol consumption while taking Lenakast-10 Capsule 30's as it might cause increased dizziness.

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Pregnancy

Unsafe

Lenakast-10 Capsule 30's should not be taken during pregnancy as it causes severe birth defects or death to an unborn baby. Use highly effective contraception if you are a woman of child-bearing age. Inform your doctor if you are pregnant, think you are pregnant or planning for pregnancy.

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Breast Feeding

Unsafe

Avoid breastfeeding while taking Lenakast-10 Capsule 30's as it is unknown if Lenakast-10 Capsule 30's passes into breastmilk.

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Driving

Unsafe

Lenakast-10 Capsule 30's may cause dizziness, sleepiness, and blurred vision. Do not drive or operate heavy machinery unless you are alert.

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Liver

Caution

Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Dose adjustment may be necessary. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Unsafe

Lenakast-10 Capsule 30's is not recommended for children below 18years as the safety and effectiveness have not been established.

FAQs

Lenakast-10 Capsule 30's is used to treat multiple myeloma, myelodysplastic syndromes, mantle cell lymphoma, and follicular lymphoma. It is also used to treat a type of myelodysplastic syndrome (MDS) known as deletion 5q MDS, where part of chromosome 5 is missing.

Lenakast-10 Capsule 30's works by helping the body’s immune system and directly attacks cancer. It stops the development of cancer cells, stops the blood vessels growing in cancer, and stimulates the part of the immune system to attack the cancer cells.

Do not stop taking Lenakast-10 Capsule 30's on your own. You are advised to take Lenakast-10 Capsule 30's for as long as your doctor has prescribed it for you, depending on your medical condition. Do not be reluctant to speak with your doctor if you experience any difficulty while taking Lenakast-10 Capsule 30's.

No, it is not safe to father a child while taking Lenakast-10 Capsule 30's. Lenakast-10 Capsule 30's can pass into human semen. During sexual activity with females of reproductive potential, always use effective contraception such as latex or synthetic condom while taking Lenakast-10 Capsule 30's and for at least 4weeks after discontinuing Lenakast-10 Capsule 30's, even if you have undergone a successful vasectomy. Male patients taking Lenakast-10 Capsule 30's must not donate semen whilst taking Lenakast-10 Capsule 30's and for 4weeks after discontinuing Lenakast-10 Capsule 30's.

Patients taking Lenakast-10 Capsule 30's must not donate blood during the treatment with Lenakast-10 Capsule 30's and for 1month after discontinuation of Lenakast-10 Capsule 30's as the donated blood might be given to pregnant women whose foetus should not be exposed to Lenakast-10 Capsule 30's since it causes severe birth defects.

People with multiple myeloma taking Lenakast-10 Capsule 30's may have an increased risk for blood clots in veins, arteries, and lungs. The risk is even higher if you are taking dexamethasone with Lenakast-10 Capsule 30's for treating multiple myeloma. Consult your doctor immediately if you notice symptoms such as shortness of breath, chest pain, and swelling in the legs or arm.

Lenakast-10 Capsule 30's might cause neutropenia (low white blood cells) or thrombocytopenia (low platelets). Blood count should be checked regularly during treatment with Lenakast-10 Capsule 30's.

You should take Lenakast-10 Capsule 30's at the same time every day. You can take the capsules with or without food.

Dose adjustment may be necessary. Please consult your doctor if you have kidney impairment or any concerns regarding this.

Some people treated with Lenakast-10 Capsule 30's may rarely get other cancers. Consult your doctor for more details.

Yes, you will need to get regular blood tests while taking Lenakast-10 Capsule 30's. Your doctor may suggest taking tests before and during treatment.

Yes, even women with fertility difficulties must take birth control while taking this medication. You must also take a negative pregnancy test 10 to 14 days before treatment and again 24 hours before. You will be tested for pregnancy every 2 to 4 weeks while on Lenakast-10 Capsule 30's.

Lenakast-10 Capsule 30's contains Lenalidomide as an active ingredient.

Common side effects of Lenakast-10 Capsule 30's may include fatigue, constipation, diarrhoea, muscle cramps, nausea, headache, upper respiratory tract infection, dizziness, shortness of breath, and weakness. Talk with your doctor if you persistently experience any of these side effects.

Lenakast-10 Capsule 30's should not be taken during pregnancy as it causes severe birth defects or death to an unborn baby. Use highly effective contraception if you are a woman of childbearing age. Inform your doctor if you are pregnant, think you are pregnant or planning for pregnancy.

Avoid breastfeeding while taking Lenakast-10 Capsule 30's as it is unknown if Lenakast-10 Capsule 30's passes into breastmilk.

Country of origin

India

Manufacturer/Marketer address

Plot No.-96, Kh No.-40/13, Extn-1B, Nangloi Delhi West Delhi Dl 110041 In
Other Info - LEN0173

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