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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Kabilen 10 mg Tablet is used to treat cancers such as multiple myeloma, myelodysplastic syndromes, mantle cell lymphoma, and follicular lymphoma. It contains lenalidomide, which works by stimulating the immune system to attack the cancer cells. It also kills the abnormal cells in the bone marrow and helps the bone marrow to produce normal blood cells. In some cases, this medicine may cause side effects, such as fatigue, constipation, diarrhoea, and weakness. Before taking this medicine, inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.
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Composition :

LENALIDOMIDE-10MG

Manufacturer/Marketer :

Fresenius Kabi India Pvt Ltd

Consume Type :

ORAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Kabilen 10 mg Tablet

Kabilen 10 mg Tablet is used to treat multiple myeloma, myelodysplastic syndromes, mantle cell lymphoma, and follicular lymphoma. Kabilen 10 mg Tablet is used to treat a type of myelodysplastic syndromes (MDS) known as deletion 5q MDS, where part of chromosome 5 is missing.
 
Kabilen 10 mg Tablet contains ‘lenalidomide’, which works by helping the body’s immune system and directly attacks cancer. It stops the development of cancer cells, stops the blood vessels growing in cancer, and stimulates the part of the immune system to attack the cancer cells. Kabilen 10 mg Tablet kills the abnormal cells in the bone marrow and helps the bone marrow to produce normal blood cells.
 
You are advised to take Kabilen 10 mg Tablet for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain common side effects, such as fatigue, constipation, diarrhoea, muscle cramps, nausea, headache, upper respiratory tract infection, dizziness, shortness of breath, and weakness. Talk with your doctor if you experience any of these side effects persistently.
 
Avoid taking Kabilen 10 mg Tablet if you are pregnant or breastfeeding. Kabilen 10 mg Tablet may cause dizziness, sleepiness, tiredness, and blurred vision, so drive only if you are alert. Kabilen 10 mg Tablet is not recommended for children below 18 years as safety and effectiveness have not been established. Men and women taking Kabilen 10 mg Tablet must use effective contraception. Inform your doctor regarding your health condition and medications before taking Kabilen 10 mg Tablet to rule out any interactions.

Uses of Kabilen 10 mg Tablet

Treatment of Multiple myeloma, myelodysplastic syndromes, mantle cell lymphoma, and follicular lymphoma.

Directions for Use

Swallow Kabilen 10 mg Tablet as a whole with water; do not crush or chew it.

Medicinal Benefits

Kabilen 10 mg Tablet belongs to the group of medicines called immunomodulatory agents. Kabilen 10 mg Tablet is used to treat multiple myeloma, myelodysplastic syndromes, mantle cell lymphoma, and follicular lymphoma. Kabilen 10 mg Tablet works by helping the body’s immune system and directly attacks cancer. It stops the development of cancer cells, stops the blood vessels growing in cancer, and stimulates the part of the immune system to attack the cancer cells. Kabilen 10 mg Tablet kills the abnormal cells in the bone marrow and helps the bone marrow to produce normal blood cells. Kabilen 10 mg Tablet is used to treat a type of myelodysplastic syndromes (MDS) known as deletion 5q MDS, where part of chromosome 5 is missing.

How Kabilen 10 mg Tablet Works

Kabilen 10 mg Tablet contains ‘lenalidomide’, which works by helping the body’s immune system and directly attacks cancer. It stops the development of cancer cells, stops the blood vessels growing in cancer, and stimulates the part of the immune system to attack the cancer cells. Kabilen 10 mg Tablet kills the abnormal cells in the bone marrow and helps the bone marrow to produce normal blood cells.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Kabilen 10 mg Tablet

  • Weakness
  • Constipation
  • Diarrhoea
  • Nausea
  • Vomiting
  • Stomach pain
  • Heartburn
  • Shortness of breath
  • Headache
  • Muscle/bone/back pain
  • Decrease in red blood cell count
  • Fever and flu-like symptoms
  • Decreased appetite
  • Blurred vision
  • Upper respiratory tract infection
  • Dry mouth

What if I have taken an overdose of Kabilen 10 mg Tablet

Take Kabilen 10 mg Tablet only as prescribed by the physician. Do not exceed the recommended dose, as it might cause an overdose. If you suspect you have taken an overdose, seek immediate medical attention.

Drug Warnings

Do not take Kabilen 10 mg Tablet if you are allergic to any of its components. Inform your doctor if you have/had blood clots, heart attack, neuropathy, slow heart rate, high blood pressure, low blood pressure, high cholesterol levels, infections/signs of infections, viral infection, HIV, hepatitis B, epilepsy, liver or kidney problems. Do not take Kabilen 10 mg Tablet if you are pregnant, as it might cause severe birth defects or the death of the unborn baby. Avoid taking Kabilen 10 mg Tablet if you are breastfeeding as it is not unknown if it passes into breastmilk. Kabilen 10 mg Tablet may cause dizziness, sleepiness and blurred vision, so drive only if you are alert. Kabilen 10 mg Tablet is not recommended for use in children. Avoid consuming alcohol along with Kabilen 10 mg Tablet as it could lead to increased dizziness and sleepiness. Let your doctor know regarding your health condition and medications you are taking, including over the counter and herbal products.

Drug-Drug Interactions

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LenalidomideAnakinra
Critical
LenalidomideYellow fever vaccine
Critical

Drug-Drug Interactions

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LenalidomideAnakinra
Critical
How does the drug interact with Kabilen 10 mg Tablet:
Taking anakinra with Kabilen 10 mg Tablet can increase the risk of negative side effects.

How to manage the interaction:
Taking Kabilen 10 mg Tablet with Anakinra is not recommended, but it can be taken if advised by your doctor. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
LenalidomideYellow fever vaccine
Critical
How does the drug interact with Kabilen 10 mg Tablet:
When combining the Yellow fever vaccine with Kabilen 10 mg Tablet, there's an increased risk of vaccine-related infections or a diminished vaccine response.

How to manage the interaction:
Taking Kabilen 10 mg Tablet with Yellow fever vaccine is not recommended, but it can be taken if prescribed by a doctor. However, contact a doctor if you experience any symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, discomfort, or burning during urination. Do not stop taking any medications without consulting a doctor.
LenalidomideBCG vaccine
Critical
How does the drug interact with Kabilen 10 mg Tablet:
Combining the BCG vaccine with Kabilen 10 mg Tablet increases the risk of vaccine-related infections or a diminished vaccine response.

How to manage the interaction:
Taking Kabilen 10 mg Tablet with BCG vaccine is not recommended, but it can be taken if prescribed by a doctor. However, contact a doctor if you experience any symptoms of infection, such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, discomfort, or burning during urination. Do not stop taking any medications without consulting a doctor.
LenalidomideRotavirus vaccine
Critical
How does the drug interact with Kabilen 10 mg Tablet:
Administering the Rotavirus vaccine together with Kabilen 10 mg Tablet may increase the risk of infections.

How to manage the interaction:
Taking Kabilen 10 mg Tablet with the Rotavirus vaccine is not recommended, but it can be taken if prescribed by a doctor. It is recommended to take the rotavirus vaccine a few weeks after the treatment with Kabilen 10 mg Tablet. Do not stop using any medications without consulting a doctor.
LenalidomideFilgrastim
Severe
How does the drug interact with Kabilen 10 mg Tablet:
Using filgrastim together with Kabilen 10 mg Tablet can reduce the effect of filgrastim.

How to manage the interaction:
Co-administration of Filgrastim with Kabilen 10 mg Tablet can possibly result in an interaction, but it can be taken if your doctor has advised it. Do not discontinue any medications without consulting a doctor.
LenalidomideLomitapide
Severe
How does the drug interact with Kabilen 10 mg Tablet:
Kabilen 10 mg Tablet can cause liver problems, and combining it with other drugs, such as Lomitapide, can raise the risk.

How to manage the interaction:
There may be a possibility of interaction between Kabilen 10 mg Tablet and Lomitapide, but it can be taken if prescribed by a doctor. If you have any of these symptoms: fever, chills, joint pain, swelling, bruising, skin rash, itching, bleeding, feeling tired, feeling sick, stomach ache, dark urine, or liver problems, contact your doctor immediately. Do not stop using any medications without talking to your doctor.
LenalidomideDiethylstilbestrol
Severe
How does the drug interact with Kabilen 10 mg Tablet:
Taking Kabilen 10 mg Tablet together with diethylstilbestrol may increase the risk of blood clots.

How to manage the interaction:
Although there is an interaction between Kabilen 10 mg Tablet and diethylstilbestrol, it can be taken if your doctor has advised it. However, if you experience chest pain, shortness of breath, difficulty breathing, coughing up blood, sudden loss of vision, pain, redness or swelling in an arm or leg, and numbness or weakness on one side of the body, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
LenalidomideFluvastatin
Severe
How does the drug interact with Kabilen 10 mg Tablet:
Coadministration of fluvastatin and Kabilen 10 mg Tablet together may increase the risk of a condition called rhabdomyolysis (the breakdown of skeletal muscle).

How to manage the interaction:
Although there is an interaction between Kabilen 10 mg Tablet and fluvastatin, it can be taken if your doctor has advised it. However, if you experience unexplained muscle pain, tenderness, or weakness, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
LenalidomideOspemifene
Severe
How does the drug interact with Kabilen 10 mg Tablet:
Coadministration of Kabilen 10 mg Tablet and ospemifene may increase the risk of blood clots.

How to manage the interaction:
Although there is an interaction between Kabilen 10 mg Tablet and ospemifene, it can be taken if prescribed by a doctor. However, if you experience chest pain, shortness of breath, difficulty breathing, coughing up blood, sudden loss of vision, pain, redness or swelling in an arm or leg, and numbness or weakness on one side of the body, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
LenalidomideLeflunomide
Severe
How does the drug interact with Kabilen 10 mg Tablet:
Combining Kabilen 10 mg Tablet with Leflunomide can increase the risk and severity of side effects.

How to manage the interaction:
Although taking Kabilen 10 mg Tablet and Leflunomide together can evidently cause an interaction, it can be taken if your doctor has suggested it. If you have any of these symptoms, contact your doctor right away. These symptoms include infection, liver problems, fever, chills, diarrhea, sore throat, muscle pain, difficulty breathing, weight loss, pain, joint pain, swelling, bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark urine, or bleeding. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat a healthy diet and exercise regularly to maintain proper weight.

  • Avoid smoking and alcohol consumption.

  • Include food rich in iron, such as lean red meat, raisins, bell peppers, Brussel sprouts, and broccoli.

  • To prevent constipation, consume fibre-rich foods such as whole grains, broccoli, dried fruits, nuts, beans, apples, oranges, and pears. 

Habit Forming

No

Therapeutic Class

IMMUNOMODULATORS

Kabilen 10 mg Tablet Substitute

Substitutes safety advice
  • Lenangio 10 Capsule 10's

    911.70per tablet
  • Lenalid 10 Capsule 30's

    123.44per tablet
  • Laviat 10 mg Capsule 10's

    132.57per tablet
  • Lenmid 10 Capsule 10's

    53.30per tablet
  • Myelosafe Capsule 10's

    by AYUR

    11.52per tablet
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Alcohol

Unsafe

You are recommended to avoid alcohol consumption while taking Kabilen 10 mg Tablet as it might cause increased dizziness.

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Pregnancy

Unsafe

Kabilen 10 mg Tablet should not be taken during pregnancy as it causes severe birth defects or death to an unborn baby. Use highly effective contraception if you are a woman of child-bearing age. Inform your doctor if you are pregnant, think you are pregnant or planning for pregnancy.

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Breast Feeding

Unsafe

Avoid breastfeeding while taking Kabilen 10 mg Tablet as it is unknown if Kabilen 10 mg Tablet passes into breastmilk.

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Driving

Unsafe

Kabilen 10 mg Tablet may cause dizziness, sleepiness, and blurred vision. Do not drive or operate heavy machinery unless you are alert.

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Liver

Caution

Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Dose adjustment may be necessary. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Unsafe

Kabilen 10 mg Tablet is not recommended for children below 18years as the safety and effectiveness have not been established.

FAQs

Kabilen 10 mg Tablet is used to treat multiple myeloma, myelodysplastic syndromes, mantle cell lymphoma, and follicular lymphoma. It is also used to treat a type of myelodysplastic syndrome (MDS) known as deletion 5q MDS, where part of chromosome 5 is missing.
Kabilen 10 mg Tablet works by helping the body’s immune system and directly attacks cancer. It stops the development of cancer cells, stops the blood vessels growing in cancer, and stimulates the part of the immune system to attack the cancer cells.
Do not stop taking Kabilen 10 mg Tablet on your own. You are advised to take Kabilen 10 mg Tablet for as long as your doctor has prescribed it for you, depending on your medical condition. Do not be reluctant to speak with your doctor if you experience any difficulty while taking Kabilen 10 mg Tablet.
No, it is not safe to father a child while taking Kabilen 10 mg Tablet. Kabilen 10 mg Tablet can pass into human semen. During sexual activity with females of reproductive potential, always use effective contraception such as latex or synthetic condom while taking Kabilen 10 mg Tablet and for at least 4weeks after discontinuing Kabilen 10 mg Tablet, even if you have undergone a successful vasectomy. Male patients taking Kabilen 10 mg Tablet must not donate semen whilst taking Kabilen 10 mg Tablet and for 4weeks after discontinuing Kabilen 10 mg Tablet.
Patients taking Kabilen 10 mg Tablet must not donate blood during the treatment with Kabilen 10 mg Tablet and for 1month after discontinuation of Kabilen 10 mg Tablet as the donated blood might be given to pregnant women whose foetus should not be exposed to Kabilen 10 mg Tablet since it causes severe birth defects.
People with multiple myeloma taking Kabilen 10 mg Tablet may have an increased risk for blood clots in veins, arteries, and lungs. The risk is even higher if you are taking dexamethasone with Kabilen 10 mg Tablet for treating multiple myeloma. Consult your doctor immediately if you notice symptoms such as shortness of breath, chest pain, and swelling in the legs or arm.
Kabilen 10 mg Tablet might cause neutropenia (low white blood cells) or thrombocytopenia (low platelets). Blood count should be checked regularly during treatment with Kabilen 10 mg Tablet.
You should take Kabilen 10 mg Tablet at the same time every day. You can take the capsules with or without food.
Dose adjustment may be necessary. Please consult your doctor if you have kidney impairment or any concerns regarding this.
Some people treated with Kabilen 10 mg Tablet may rarely get other cancers. Consult your doctor for more details.
Yes, you will need to get regular blood tests while taking Kabilen 10 mg Tablet. Your doctor may suggest taking tests before and during treatment.
Yes, even women with fertility difficulties must take birth control while taking this medication. You must also take a negative pregnancy test 10 to 14 days before treatment and again 24 hours before. You will be tested for pregnancy every 2 to 4 weeks while on Kabilen 10 mg Tablet.
Kabilen 10 mg Tablet contains Lenalidomide as an active ingredient.
Common side effects of Kabilen 10 mg Tablet may include fatigue, constipation, diarrhoea, muscle cramps, nausea, headache, upper respiratory tract infection, dizziness, shortness of breath, and weakness. Talk with your doctor if you persistently experience any of these side effects.
Kabilen 10 mg Tablet should not be taken during pregnancy as it causes severe birth defects or death to an unborn baby. Use highly effective contraception if you are a woman of childbearing age. Inform your doctor if you are pregnant, think you are pregnant or planning for pregnancy.
Avoid breastfeeding while taking Kabilen 10 mg Tablet as it is unknown if Kabilen 10 mg Tablet passes into breastmilk.

Country of origin

India

Manufacturer/Marketer address

Fresenius Kabi Ag , Else-Krã¶Ner-Straãÿe 1 , 61352 Bad Homburg , Germany
Other Info - KAB0040

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