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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Oct 11, 2024 | 2:34 PM IST
Kabilen 10 mg Tablet is used to treat cancers such as multiple myeloma, myelodysplastic syndromes, mantle cell lymphoma, and follicular lymphoma. It contains lenalidomide, which works by stimulating the immune system to attack the cancer cells. It also kills the abnormal cells in the bone marrow and helps the bone marrow to produce normal blood cells. In some cases, this medicine may cause side effects, such as fatigue, constipation, diarrhoea, and weakness. Before taking this medicine, inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.
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Manufacturer/Marketer

Fresenius Kabi India Pvt Ltd

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About Kabilen 10 mg Tablet

Kabilen 10 mg Tablet is used to treat multiple myeloma, myelodysplastic syndromes, mantle cell lymphoma, and follicular lymphoma. Kabilen 10 mg Tablet is used to treat a type of myelodysplastic syndromes (MDS) known as deletion 5q MDS, where part of chromosome 5 is missing.
 
Kabilen 10 mg Tablet contains ‘lenalidomide’, which works by helping the body’s immune system and directly attacks cancer. It stops the development of cancer cells, stops the blood vessels growing in cancer, and stimulates the part of the immune system to attack the cancer cells. Kabilen 10 mg Tablet kills the abnormal cells in the bone marrow and helps the bone marrow to produce normal blood cells.
 
You are advised to take Kabilen 10 mg Tablet for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain common side effects, such as fatigue, constipation, diarrhoea, muscle cramps, nausea, headache, upper respiratory tract infection, dizziness, shortness of breath, and weakness. Talk with your doctor if you experience any of these side effects persistently.
 
Avoid taking Kabilen 10 mg Tablet if you are pregnant or breastfeeding. Kabilen 10 mg Tablet may cause dizziness, sleepiness, tiredness, and blurred vision, so drive only if you are alert. Kabilen 10 mg Tablet is not recommended for children below 18 years as safety and effectiveness have not been established. Men and women taking Kabilen 10 mg Tablet must use effective contraception. Inform your doctor regarding your health condition and medications before taking Kabilen 10 mg Tablet to rule out any interactions.

Uses of Kabilen 10 mg Tablet

Treatment of Multiple myeloma, myelodysplastic syndromes, mantle cell lymphoma, and follicular lymphoma.

Medicinal Benefits

Kabilen 10 mg Tablet belongs to the group of medicines called immunomodulatory agents. Kabilen 10 mg Tablet is used to treat multiple myeloma, myelodysplastic syndromes, mantle cell lymphoma, and follicular lymphoma. Kabilen 10 mg Tablet works by helping the body’s immune system and directly attacks cancer. It stops the development of cancer cells, stops the blood vessels growing in cancer, and stimulates the part of the immune system to attack the cancer cells. Kabilen 10 mg Tablet kills the abnormal cells in the bone marrow and helps the bone marrow to produce normal blood cells. Kabilen 10 mg Tablet is used to treat a type of myelodysplastic syndromes (MDS) known as deletion 5q MDS, where part of chromosome 5 is missing.

Directions for Use

Swallow Kabilen 10 mg Tablet as a whole with water; do not crush or chew it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Kabilen 10 mg Tablet

  • Weakness
  • Constipation
  • Diarrhoea
  • Nausea
  • Vomiting
  • Stomach pain
  • Heartburn
  • Shortness of breath
  • Headache
  • Muscle/bone/back pain
  • Decrease in red blood cell count
  • Fever and flu-like symptoms
  • Decreased appetite
  • Blurred vision
  • Upper respiratory tract infection
  • Dry mouth

Drug Warnings

Do not take Kabilen 10 mg Tablet if you are allergic to any of its components. Inform your doctor if you have/had blood clots, heart attack, neuropathy, slow heart rate, high blood pressure, low blood pressure, high cholesterol levels, infections/signs of infections, viral infection, HIV, hepatitis B, epilepsy, liver or kidney problems. Do not take Kabilen 10 mg Tablet if you are pregnant, as it might cause severe birth defects or the death of the unborn baby. Avoid taking Kabilen 10 mg Tablet if you are breastfeeding as it is not unknown if it passes into breastmilk. Kabilen 10 mg Tablet may cause dizziness, sleepiness and blurred vision, so drive only if you are alert. Kabilen 10 mg Tablet is not recommended for use in children. Avoid consuming alcohol along with Kabilen 10 mg Tablet as it could lead to increased dizziness and sleepiness. Let your doctor know regarding your health condition and medications you are taking, including over the counter and herbal products.

Drug Interactions

Drug-Drug Interactions: Kabilen 10 mg Tablet may interact with digitalis glycosides (digoxin), blood thinner (warfarin), and hormone (erythropoietin).

Drug-Food Interactions: No interactions found/established.

Drug-Disease Interactions: Inform your doctor if you have anaemia, blood clots, infections, heart, kidney, or liver problems.

Drug-Drug Interactions Checker List

  • DIGOXIN
  • WARFARIN
  • ERYTHROPOIETIN

Habit Forming

No

Diet & Lifestyle Advise

  • Eat a healthy diet and exercise regularly to maintain proper weight.

  • Avoid smoking and alcohol consumption.

  • Include food rich in iron, such as lean red meat, raisins, bell peppers, Brussel sprouts, and broccoli.

  • To prevent constipation, consume fibre-rich foods such as whole grains, broccoli, dried fruits, nuts, beans, apples, oranges, and pears. 

Special Advise

  • Do not take Kabilen 10 mg Tablet if you are pregnant as it might cause severe birth defects or death of the unborn baby.

  • Male patients taking Kabilen 10 mg Tablet must not donate semen and should use effective contraception during sexual activity even though they have undergone vasectomy.

  • You must not donate blood while taking Kabilen 10 mg Tablet and for 4weeks after discontinuing Kabilen 10 mg Tablet.

  • Kabilen 10 mg Tablet might increase the risk of blood clots. Inform your doctor if you notice any symptoms such as chest pain, shortness of breath, swelling of the arm or leg.

  • Kabilen 10 mg Tablet might cause abnormal/increase in liver test results, inform the person doing the test that you are taking Kabilen 10 mg Tablet.

  • Kabilen 10 mg Tablet might increase/decrease your blood sugar levels. Regularly monitor blood glucose levels while taking Kabilen 10 mg Tablet. Consult your doctor if you are diabetic.

  • Inform your doctor if you have any kidney dysfunction as Kabilen 10 mg Tablet might cause kidney problems.

  • Regular blood tests are advised before and during treatment with Kabilen 10 mg Tablet.

Disease/Condition Glossary

Multiple myeloma: Multiple myeloma is a type of cancer that affects a type of white blood cell called a plasma cell. These cells collect in the bone marrow and divide uncontrollably, leading to kidney and bone damage. Symptoms include bone pain, loss of appetite, fever, and frequent infections.

Myelodysplastic syndromes: It is a group of disorders that occur due to abnormal functioning of blood cells. Symptoms include shortness of breath, anaemia, fatigue, need for blood transfusion, and risk of infections.

Mantle cell lymphoma: It is a cancer of the lymph tissue where the B-cells or B lymphocytes (a type of white blood cells) grow in an uncontrolled manner and build up in the lymph tissue, blood or bone marrow.

Follicular lymphoma: It is a slow-growing cancer that affects B lymphocytes, a type of white blood cells that help fight infection. In the case of follicular lymphoma, too many B lymphocytes build up in the blood, lymph nodes, bone marrow, and spleen.

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Alcohol

Unsafe

You are recommended to avoid alcohol consumption while taking Kabilen 10 mg Tablet as it might cause increased dizziness.

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Pregnancy

Unsafe

Kabilen 10 mg Tablet should not be taken during pregnancy as it causes severe birth defects or death to an unborn baby. Use highly effective contraception if you are a woman of child-bearing age. Inform your doctor if you are pregnant, think you are pregnant or planning for pregnancy.

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Breast Feeding

Unsafe

Avoid breastfeeding while taking Kabilen 10 mg Tablet as it is unknown if Kabilen 10 mg Tablet passes into breastmilk.

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Driving

Unsafe

Kabilen 10 mg Tablet may cause dizziness, sleepiness, and blurred vision. Do not drive or operate heavy machinery unless you are alert.

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Liver

Caution

Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Dose adjustment may be necessary. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Unsafe

Kabilen 10 mg Tablet is not recommended for children below 18years as the safety and effectiveness have not been established.

Country of origin

India

Manufacturer/Marketer address

Fresenius Kabi Ag , Else-Krã¶Ner-Straãÿe 1 , 61352 Bad Homburg , Germany
Other Info - KAB0040

Author Details

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FAQs

Kabilen 10 mg Tablet is used to treat multiple myeloma, myelodysplastic syndromes, mantle cell lymphoma, and follicular lymphoma. It is also used to treat a type of myelodysplastic syndrome (MDS) known as deletion 5q MDS, where part of chromosome 5 is missing.
Kabilen 10 mg Tablet works by helping the body’s immune system and directly attacks cancer. It stops the development of cancer cells, stops the blood vessels growing in cancer, and stimulates the part of the immune system to attack the cancer cells.
Do not stop taking Kabilen 10 mg Tablet on your own. You are advised to take Kabilen 10 mg Tablet for as long as your doctor has prescribed it for you, depending on your medical condition. Do not be reluctant to speak with your doctor if you experience any difficulty while taking Kabilen 10 mg Tablet.
No, it is not safe to father a child while taking Kabilen 10 mg Tablet. Kabilen 10 mg Tablet can pass into human semen. During sexual activity with females of reproductive potential, always use effective contraception such as latex or synthetic condom while taking Kabilen 10 mg Tablet and for at least 4weeks after discontinuing Kabilen 10 mg Tablet, even if you have undergone a successful vasectomy. Male patients taking Kabilen 10 mg Tablet must not donate semen whilst taking Kabilen 10 mg Tablet and for 4weeks after discontinuing Kabilen 10 mg Tablet.
Patients taking Kabilen 10 mg Tablet must not donate blood during the treatment with Kabilen 10 mg Tablet and for 1month after discontinuation of Kabilen 10 mg Tablet as the donated blood might be given to pregnant women whose foetus should not be exposed to Kabilen 10 mg Tablet since it causes severe birth defects.
People with multiple myeloma taking Kabilen 10 mg Tablet may have an increased risk for blood clots in veins, arteries, and lungs. The risk is even higher if you are taking dexamethasone with Kabilen 10 mg Tablet for treating multiple myeloma. Consult your doctor immediately if you notice symptoms such as shortness of breath, chest pain, and swelling in the legs or arm.
Kabilen 10 mg Tablet might cause neutropenia (low white blood cells) or thrombocytopenia (low platelets). Blood count should be checked regularly during treatment with Kabilen 10 mg Tablet.
You should take Kabilen 10 mg Tablet at the same time every day. You can take the capsules with or without food.
Dose adjustment may be necessary. Please consult your doctor if you have kidney impairment or any concerns regarding this.
Some people treated with Kabilen 10 mg Tablet may rarely get other cancers. Consult your doctor for more details.
Yes, you will need to get regular blood tests while taking Kabilen 10 mg Tablet. Your doctor may suggest taking tests before and during treatment.
Yes, even women with fertility difficulties must take birth control while taking this medication. You must also take a negative pregnancy test 10 to 14 days before treatment and again 24 hours before. You will be tested for pregnancy every 2 to 4 weeks while on Kabilen 10 mg Tablet.
Kabilen 10 mg Tablet contains Lenalidomide as an active ingredient.
Common side effects of Kabilen 10 mg Tablet may include fatigue, constipation, diarrhoea, muscle cramps, nausea, headache, upper respiratory tract infection, dizziness, shortness of breath, and weakness. Talk with your doctor if you persistently experience any of these side effects.
Kabilen 10 mg Tablet should not be taken during pregnancy as it causes severe birth defects or death to an unborn baby. Use highly effective contraception if you are a woman of childbearing age. Inform your doctor if you are pregnant, think you are pregnant or planning for pregnancy.
Avoid breastfeeding while taking Kabilen 10 mg Tablet as it is unknown if Kabilen 10 mg Tablet passes into breastmilk.

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