apollo
0
Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Giolen 10mg Capsule is used to treat cancers such as multiple myeloma, myelodysplastic syndromes, mantle cell lymphoma, and follicular lymphoma. It contains lenalidomide, which works by stimulating the immune system to attack the cancer cells. It also kills the abnormal cells in the bone marrow and helps the bone marrow to produce normal blood cells. In some cases, this medicine may cause side effects, such as fatigue, constipation, diarrhoea, and weakness. Before taking this medicine, inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.
Read more
rxMedicinePrescription drug

Whats That

tooltip
Consult Doctor

Composition :

LENALIDOMIDE-10MG

Consume Type :

ORAL

Return Policy :

Not Returnable

About Giolen 10mg Capsule

Giolen 10mg Capsule is used to treat multiple myeloma, myelodysplastic syndromes, mantle cell lymphoma, and follicular lymphoma. Giolen 10mg Capsule is used to treat a type of myelodysplastic syndromes (MDS) known as deletion 5q MDS, where part of chromosome 5 is missing.
 
Giolen 10mg Capsule contains ‘lenalidomide’, which works by helping the body’s immune system and directly attacks cancer. It stops the development of cancer cells, stops the blood vessels growing in cancer, and stimulates the part of the immune system to attack the cancer cells. Giolen 10mg Capsule kills the abnormal cells in the bone marrow and helps the bone marrow to produce normal blood cells.
 
You are advised to take Giolen 10mg Capsule for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain common side effects, such as fatigue, constipation, diarrhoea, muscle cramps, nausea, headache, upper respiratory tract infection, dizziness, shortness of breath, and weakness. Talk with your doctor if you experience any of these side effects persistently.
 
Avoid taking Giolen 10mg Capsule if you are pregnant or breastfeeding. Giolen 10mg Capsule may cause dizziness, sleepiness, tiredness, and blurred vision, so drive only if you are alert. Giolen 10mg Capsule is not recommended for children below 18 years as safety and effectiveness have not been established. Men and women taking Giolen 10mg Capsule must use effective contraception. Inform your doctor regarding your health condition and medications before taking Giolen 10mg Capsule to rule out any interactions.

Uses of Giolen 10mg Capsule

Treatment of Multiple myeloma, myelodysplastic syndromes, mantle cell lymphoma, and follicular lymphoma.

Directions for Use

Swallow Giolen 10mg Capsule as a whole with water; do not crush or chew it.

Medicinal Benefits

Giolen 10mg Capsule belongs to the group of medicines called immunomodulatory agents. Giolen 10mg Capsule is used to treat multiple myeloma, myelodysplastic syndromes, mantle cell lymphoma, and follicular lymphoma. Giolen 10mg Capsule works by helping the body’s immune system and directly attacks cancer. It stops the development of cancer cells, stops the blood vessels growing in cancer, and stimulates the part of the immune system to attack the cancer cells. Giolen 10mg Capsule kills the abnormal cells in the bone marrow and helps the bone marrow to produce normal blood cells. Giolen 10mg Capsule is used to treat a type of myelodysplastic syndromes (MDS) known as deletion 5q MDS, where part of chromosome 5 is missing.

How Giolen 10mg Capsule Works

Giolen 10mg Capsule contains ‘lenalidomide’, which works by helping the body’s immune system and directly attacks cancer. It stops the development of cancer cells, stops the blood vessels growing in cancer, and stimulates the part of the immune system to attack the cancer cells. Giolen 10mg Capsule kills the abnormal cells in the bone marrow and helps the bone marrow to produce normal blood cells.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Giolen 10mg Capsule

  • Weakness
  • Constipation
  • Diarrhoea
  • Nausea
  • Vomiting
  • Stomach pain
  • Heartburn
  • Shortness of breath
  • Headache
  • Muscle/bone/back pain
  • Decrease in red blood cell count
  • Fever and flu-like symptoms
  • Decreased appetite
  • Blurred vision
  • Upper respiratory tract infection
  • Dry mouth

What if I have taken an overdose of Giolen 10mg Capsule

Take Giolen 10mg Capsule only as prescribed by the physician. Do not exceed the recommended dose, as it might cause an overdose. If you suspect you have taken an overdose, seek immediate medical attention.

Drug Warnings

Do not take Giolen 10mg Capsule if you are allergic to any of its components. Inform your doctor if you have/had blood clots, heart attack, neuropathy, slow heart rate, high blood pressure, low blood pressure, high cholesterol levels, infections/signs of infections, viral infection, HIV, hepatitis B, epilepsy, liver or kidney problems. Do not take Giolen 10mg Capsule if you are pregnant, as it might cause severe birth defects or the death of the unborn baby. Avoid taking Giolen 10mg Capsule if you are breastfeeding as it is not unknown if it passes into breastmilk. Giolen 10mg Capsule may cause dizziness, sleepiness and blurred vision, so drive only if you are alert. Giolen 10mg Capsule is not recommended for use in children. Avoid consuming alcohol along with Giolen 10mg Capsule as it could lead to increased dizziness and sleepiness. Let your doctor know regarding your health condition and medications you are taking, including over the counter and herbal products.

Drug-Drug Interactions

verifiedApollotooltip
LenalidomideAnakinra
Critical
LenalidomideYellow fever vaccine
Critical

Drug-Drug Interactions

Login/Sign Up

LenalidomideAnakinra
Critical
How does the drug interact with Giolen 10mg Capsule:
Taking anakinra with Giolen 10mg Capsule can increase the risk of negative side effects.

How to manage the interaction:
Taking Giolen 10mg Capsule with Anakinra is not recommended, but it can be taken if advised by your doctor. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
LenalidomideYellow fever vaccine
Critical
How does the drug interact with Giolen 10mg Capsule:
When combining the Yellow fever vaccine with Giolen 10mg Capsule, there's an increased risk of vaccine-related infections or a diminished vaccine response.

How to manage the interaction:
Taking Giolen 10mg Capsule with Yellow fever vaccine is not recommended, but it can be taken if prescribed by a doctor. However, contact a doctor if you experience any symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, discomfort, or burning during urination. Do not stop taking any medications without consulting a doctor.
LenalidomideBCG vaccine
Critical
How does the drug interact with Giolen 10mg Capsule:
Combining the BCG vaccine with Giolen 10mg Capsule increases the risk of vaccine-related infections or a diminished vaccine response.

How to manage the interaction:
Taking Giolen 10mg Capsule with BCG vaccine is not recommended, but it can be taken if prescribed by a doctor. However, contact a doctor if you experience any symptoms of infection, such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, discomfort, or burning during urination. Do not stop taking any medications without consulting a doctor.
LenalidomideRotavirus vaccine
Critical
How does the drug interact with Giolen 10mg Capsule:
Administering the Rotavirus vaccine together with Giolen 10mg Capsule may increase the risk of infections.

How to manage the interaction:
Taking Giolen 10mg Capsule with the Rotavirus vaccine is not recommended, but it can be taken if prescribed by a doctor. It is recommended to take the rotavirus vaccine a few weeks after the treatment with Giolen 10mg Capsule. Do not stop using any medications without consulting a doctor.
LenalidomideFilgrastim
Severe
How does the drug interact with Giolen 10mg Capsule:
Using filgrastim together with Giolen 10mg Capsule can reduce the effect of filgrastim.

How to manage the interaction:
Co-administration of Filgrastim with Giolen 10mg Capsule can possibly result in an interaction, but it can be taken if your doctor has advised it. Do not discontinue any medications without consulting a doctor.
LenalidomideLomitapide
Severe
How does the drug interact with Giolen 10mg Capsule:
Giolen 10mg Capsule can cause liver problems, and combining it with other drugs, such as Lomitapide, can raise the risk.

How to manage the interaction:
There may be a possibility of interaction between Giolen 10mg Capsule and Lomitapide, but it can be taken if prescribed by a doctor. If you have any of these symptoms: fever, chills, joint pain, swelling, bruising, skin rash, itching, bleeding, feeling tired, feeling sick, stomach ache, dark urine, or liver problems, contact your doctor immediately. Do not stop using any medications without talking to your doctor.
LenalidomideDiethylstilbestrol
Severe
How does the drug interact with Giolen 10mg Capsule:
Taking Giolen 10mg Capsule together with diethylstilbestrol may increase the risk of blood clots.

How to manage the interaction:
Although there is an interaction between Giolen 10mg Capsule and diethylstilbestrol, it can be taken if your doctor has advised it. However, if you experience chest pain, shortness of breath, difficulty breathing, coughing up blood, sudden loss of vision, pain, redness or swelling in an arm or leg, and numbness or weakness on one side of the body, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
LenalidomideFluvastatin
Severe
How does the drug interact with Giolen 10mg Capsule:
Coadministration of fluvastatin and Giolen 10mg Capsule together may increase the risk of a condition called rhabdomyolysis (the breakdown of skeletal muscle).

How to manage the interaction:
Although there is an interaction between Giolen 10mg Capsule and fluvastatin, it can be taken if your doctor has advised it. However, if you experience unexplained muscle pain, tenderness, or weakness, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
LenalidomideOspemifene
Severe
How does the drug interact with Giolen 10mg Capsule:
Coadministration of Giolen 10mg Capsule and ospemifene may increase the risk of blood clots.

How to manage the interaction:
Although there is an interaction between Giolen 10mg Capsule and ospemifene, it can be taken if prescribed by a doctor. However, if you experience chest pain, shortness of breath, difficulty breathing, coughing up blood, sudden loss of vision, pain, redness or swelling in an arm or leg, and numbness or weakness on one side of the body, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
LenalidomideLeflunomide
Severe
How does the drug interact with Giolen 10mg Capsule:
Combining Giolen 10mg Capsule with Leflunomide can increase the risk and severity of side effects.

How to manage the interaction:
Although taking Giolen 10mg Capsule and Leflunomide together can evidently cause an interaction, it can be taken if your doctor has suggested it. If you have any of these symptoms, contact your doctor right away. These symptoms include infection, liver problems, fever, chills, diarrhea, sore throat, muscle pain, difficulty breathing, weight loss, pain, joint pain, swelling, bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark urine, or bleeding. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

Login/Sign Up

Diet & Lifestyle Advise

  • Eat a healthy diet and exercise regularly to maintain proper weight.

  • Avoid smoking and alcohol consumption.

  • Include food rich in iron, such as lean red meat, raisins, bell peppers, Brussel sprouts, and broccoli.

  • To prevent constipation, consume fibre-rich foods such as whole grains, broccoli, dried fruits, nuts, beans, apples, oranges, and pears. 

Habit Forming

No

Therapeutic Class

IMMUNOMODULATORS

Giolen 10mg Capsule Substitute

Substitutes safety advice
  • Lenangio 10 Capsule 10's

    911.70per tablet
  • Lenalid 10 Capsule 30's

    123.44per tablet
  • Laviat 10 mg Capsule 10's

    132.57per tablet
  • Lenmid 10 Capsule 10's

    53.30per tablet
  • Myelosafe Capsule 10's

    by AYUR

    11.52per tablet
bannner image

Alcohol

Unsafe

You are recommended to avoid alcohol consumption while taking Giolen 10mg Capsule as it might cause increased dizziness.

bannner image

Pregnancy

Unsafe

Giolen 10mg Capsule should not be taken during pregnancy as it causes severe birth defects or death to an unborn baby. Use highly effective contraception if you are a woman of child-bearing age. Inform your doctor if you are pregnant, think you are pregnant or planning for pregnancy.

bannner image

Breast Feeding

Unsafe

Avoid breastfeeding while taking Giolen 10mg Capsule as it is unknown if Giolen 10mg Capsule passes into breastmilk.

bannner image

Driving

Unsafe

Giolen 10mg Capsule may cause dizziness, sleepiness, and blurred vision. Do not drive or operate heavy machinery unless you are alert.

bannner image

Liver

Caution

Please consult your doctor if you have a liver impairment or any concerns regarding this.

bannner image

Kidney

Caution

Dose adjustment may be necessary. Please consult your doctor if you have kidney impairment or any concerns regarding this.

bannner image

Children

Unsafe

Giolen 10mg Capsule is not recommended for children below 18years as the safety and effectiveness have not been established.

FAQs

Giolen 10mg Capsule is used to treat multiple myeloma, myelodysplastic syndromes, mantle cell lymphoma, and follicular lymphoma. It is also used to treat a type of myelodysplastic syndrome (MDS) known as deletion 5q MDS, where part of chromosome 5 is missing.
Giolen 10mg Capsule works by helping the body’s immune system and directly attacks cancer. It stops the development of cancer cells, stops the blood vessels growing in cancer, and stimulates the part of the immune system to attack the cancer cells.
Do not stop taking Giolen 10mg Capsule on your own. You are advised to take Giolen 10mg Capsule for as long as your doctor has prescribed it for you, depending on your medical condition. Do not be reluctant to speak with your doctor if you experience any difficulty while taking Giolen 10mg Capsule.
No, it is not safe to father a child while taking Giolen 10mg Capsule. Giolen 10mg Capsule can pass into human semen. During sexual activity with females of reproductive potential, always use effective contraception such as latex or synthetic condom while taking Giolen 10mg Capsule and for at least 4weeks after discontinuing Giolen 10mg Capsule, even if you have undergone a successful vasectomy. Male patients taking Giolen 10mg Capsule must not donate semen whilst taking Giolen 10mg Capsule and for 4weeks after discontinuing Giolen 10mg Capsule.
Patients taking Giolen 10mg Capsule must not donate blood during the treatment with Giolen 10mg Capsule and for 1month after discontinuation of Giolen 10mg Capsule as the donated blood might be given to pregnant women whose foetus should not be exposed to Giolen 10mg Capsule since it causes severe birth defects.
People with multiple myeloma taking Giolen 10mg Capsule may have an increased risk for blood clots in veins, arteries, and lungs. The risk is even higher if you are taking dexamethasone with Giolen 10mg Capsule for treating multiple myeloma. Consult your doctor immediately if you notice symptoms such as shortness of breath, chest pain, and swelling in the legs or arm.
Giolen 10mg Capsule might cause neutropenia (low white blood cells) or thrombocytopenia (low platelets). Blood count should be checked regularly during treatment with Giolen 10mg Capsule.
You should take Giolen 10mg Capsule at the same time every day. You can take the capsules with or without food.
Dose adjustment may be necessary. Please consult your doctor if you have kidney impairment or any concerns regarding this.
Some people treated with Giolen 10mg Capsule may rarely get other cancers. Consult your doctor for more details.
Yes, you will need to get regular blood tests while taking Giolen 10mg Capsule. Your doctor may suggest taking tests before and during treatment.
Yes, even women with fertility difficulties must take birth control while taking this medication. You must also take a negative pregnancy test 10 to 14 days before treatment and again 24 hours before. You will be tested for pregnancy every 2 to 4 weeks while on Giolen 10mg Capsule.
Giolen 10mg Capsule contains Lenalidomide as an active ingredient.
Common side effects of Giolen 10mg Capsule may include fatigue, constipation, diarrhoea, muscle cramps, nausea, headache, upper respiratory tract infection, dizziness, shortness of breath, and weakness. Talk with your doctor if you persistently experience any of these side effects.
Giolen 10mg Capsule should not be taken during pregnancy as it causes severe birth defects or death to an unborn baby. Use highly effective contraception if you are a woman of childbearing age. Inform your doctor if you are pregnant, think you are pregnant or planning for pregnancy.
Avoid breastfeeding while taking Giolen 10mg Capsule as it is unknown if Giolen 10mg Capsule passes into breastmilk.

Country of origin

India

Manufacturer/Marketer address

G-1, Ashoka Estate, 24, Barakhamba Road, New Delhi - 110001
Other Info - GI29165

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
whatsapp Floating Button