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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Lenated 10mg Capsule is used to treat cancers such as multiple myeloma, myelodysplastic syndromes, mantle cell lymphoma, and follicular lymphoma. It contains lenalidomide, which works by stimulating the immune system to attack the cancer cells. It also kills the abnormal cells in the bone marrow and helps the bone marrow to produce normal blood cells. In some cases, this medicine may cause side effects, such as fatigue, constipation, diarrhoea, and weakness. Before taking this medicine, inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.
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Whats That

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Composition :

LENALIDOMIDE-10MG

Manufacturer/Marketer :

Therdose Pharma Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

About Lenated 10mg Capsule

Lenated 10mg Capsule is used to treat multiple myeloma, myelodysplastic syndromes, mantle cell lymphoma, and follicular lymphoma. Lenated 10mg Capsule is used to treat a type of myelodysplastic syndromes (MDS) known as deletion 5q MDS, where part of chromosome 5 is missing.
 
Lenated 10mg Capsule contains ‘lenalidomide’, which works by helping the body’s immune system and directly attacks cancer. It stops the development of cancer cells, stops the blood vessels growing in cancer, and stimulates the part of the immune system to attack the cancer cells. Lenated 10mg Capsule kills the abnormal cells in the bone marrow and helps the bone marrow to produce normal blood cells.
 
You are advised to take Lenated 10mg Capsule for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain common side effects, such as fatigue, constipation, diarrhoea, muscle cramps, nausea, headache, upper respiratory tract infection, dizziness, shortness of breath, and weakness. Talk with your doctor if you experience any of these side effects persistently.
 
Avoid taking Lenated 10mg Capsule if you are pregnant or breastfeeding. Lenated 10mg Capsule may cause dizziness, sleepiness, tiredness, and blurred vision, so drive only if you are alert. Lenated 10mg Capsule is not recommended for children below 18 years as safety and effectiveness have not been established. Men and women taking Lenated 10mg Capsule must use effective contraception. Inform your doctor regarding your health condition and medications before taking Lenated 10mg Capsule to rule out any interactions.

Uses of Lenated 10mg Capsule

Treatment of Multiple myeloma, myelodysplastic syndromes, mantle cell lymphoma, and follicular lymphoma.

Directions for Use

Swallow Lenated 10mg Capsule as a whole with water; do not crush or chew it.

Medicinal Benefits

Lenated 10mg Capsule belongs to the group of medicines called immunomodulatory agents. Lenated 10mg Capsule is used to treat multiple myeloma, myelodysplastic syndromes, mantle cell lymphoma, and follicular lymphoma. Lenated 10mg Capsule works by helping the body’s immune system and directly attacks cancer. It stops the development of cancer cells, stops the blood vessels growing in cancer, and stimulates the part of the immune system to attack the cancer cells. Lenated 10mg Capsule kills the abnormal cells in the bone marrow and helps the bone marrow to produce normal blood cells. Lenated 10mg Capsule is used to treat a type of myelodysplastic syndromes (MDS) known as deletion 5q MDS, where part of chromosome 5 is missing.

How Lenated 10mg Capsule Works

Lenated 10mg Capsule contains ‘lenalidomide’, which works by helping the body’s immune system and directly attacks cancer. It stops the development of cancer cells, stops the blood vessels growing in cancer, and stimulates the part of the immune system to attack the cancer cells. Lenated 10mg Capsule kills the abnormal cells in the bone marrow and helps the bone marrow to produce normal blood cells.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Lenated 10mg Capsule

  • Weakness
  • Constipation
  • Diarrhoea
  • Nausea
  • Vomiting
  • Stomach pain
  • Heartburn
  • Shortness of breath
  • Headache
  • Muscle/bone/back pain
  • Decrease in red blood cell count
  • Fever and flu-like symptoms
  • Decreased appetite
  • Blurred vision
  • Upper respiratory tract infection
  • Dry mouth

What if I have taken an overdose of Lenated 10mg Capsule

Take Lenated 10mg Capsule only as prescribed by the physician. Do not exceed the recommended dose, as it might cause an overdose. If you suspect you have taken an overdose, seek immediate medical attention.

Drug Warnings

Do not take Lenated 10mg Capsule if you are allergic to any of its components. Inform your doctor if you have/had blood clots, heart attack, neuropathy, slow heart rate, high blood pressure, low blood pressure, high cholesterol levels, infections/signs of infections, viral infection, HIV, hepatitis B, epilepsy, liver or kidney problems. Do not take Lenated 10mg Capsule if you are pregnant, as it might cause severe birth defects or the death of the unborn baby. Avoid taking Lenated 10mg Capsule if you are breastfeeding as it is not unknown if it passes into breastmilk. Lenated 10mg Capsule may cause dizziness, sleepiness and blurred vision, so drive only if you are alert. Lenated 10mg Capsule is not recommended for use in children. Avoid consuming alcohol along with Lenated 10mg Capsule as it could lead to increased dizziness and sleepiness. Let your doctor know regarding your health condition and medications you are taking, including over the counter and herbal products.

Drug-Drug Interactions

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LenalidomideBCG vaccine
Critical
LenalidomideRotavirus vaccine
Critical

Drug-Drug Interactions

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LenalidomideBCG vaccine
Critical
How does the drug interact with Lenated 10mg Capsule:
Combining the BCG vaccine with Lenated 10mg Capsule increases the risk of vaccine-related infections or a diminished vaccine response.

How to manage the interaction:
Taking Lenated 10mg Capsule with BCG vaccine is not recommended, but it can be taken if prescribed by a doctor. However, contact a doctor if you experience any symptoms of infection, such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, discomfort, or burning during urination. Do not stop taking any medications without consulting a doctor.
LenalidomideRotavirus vaccine
Critical
How does the drug interact with Lenated 10mg Capsule:
Administering the Rotavirus vaccine together with Lenated 10mg Capsule may increase the risk of infections.

How to manage the interaction:
Taking Lenated 10mg Capsule with the Rotavirus vaccine is not recommended, but it can be taken if prescribed by a doctor. It is recommended to take the rotavirus vaccine a few weeks after the treatment with Lenated 10mg Capsule. Do not stop using any medications without consulting a doctor.
LenalidomideAnakinra
Critical
How does the drug interact with Lenated 10mg Capsule:
Taking anakinra with Lenated 10mg Capsule can increase the risk of negative side effects.

How to manage the interaction:
Taking Lenated 10mg Capsule with Anakinra is not recommended, but it can be taken if advised by your doctor. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
LenalidomideYellow fever vaccine
Critical
How does the drug interact with Lenated 10mg Capsule:
When combining the Yellow fever vaccine with Lenated 10mg Capsule, there's an increased risk of vaccine-related infections or a diminished vaccine response.

How to manage the interaction:
Taking Lenated 10mg Capsule with Yellow fever vaccine is not recommended, but it can be taken if prescribed by a doctor. However, contact a doctor if you experience any symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, discomfort, or burning during urination. Do not stop taking any medications without consulting a doctor.
LenalidomideVedolizumab
Severe
How does the drug interact with Lenated 10mg Capsule:
Combining Lenated 10mg Capsule with Vedolizumab can increase the chances of experiencing harmful side effects.

How to manage the interaction:
Taking Lenated 10mg Capsule with Vedolizumab together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, contact a doctor if you experience any symptoms of infection, such as chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, discomfort, or burning during urination. Do not stop using any medications without first talking to your doctor.
LenalidomidePembrolizumab
Severe
How does the drug interact with Lenated 10mg Capsule:
Using Lenated 10mg Capsule and pembrolizumab together can increase the risk of adverse effects.

How to manage the interaction:
Taking Lenated 10mg Capsule with Pembrolizumab together can possibly result in an interaction, but it can be taken if your doctor has advised it. Do not stop using any medications without a doctor's advice.
LenalidomideFilgrastim
Severe
How does the drug interact with Lenated 10mg Capsule:
Using filgrastim together with Lenated 10mg Capsule can reduce the effect of filgrastim.

How to manage the interaction:
Co-administration of Filgrastim with Lenated 10mg Capsule can possibly result in an interaction, but it can be taken if your doctor has advised it. Do not discontinue any medications without consulting a doctor.
LenalidomideMipomersen
Severe
How does the drug interact with Lenated 10mg Capsule:
Lenated 10mg Capsule can cause liver problems, and combining it with other drugs, such as Mipomersen, can raise the risk.

How to manage the interaction:
Taking Lenated 10mg Capsule with Mipomersen together can possibly result in an interaction, but it can be taken if your doctor has advised it. If you have any of these symptoms: fever, chills, joint pain, swelling, bruising, skin rash, itching, bleeding, feeling tired, feeling sick, stomach ache, or dark urine, contact your doctor immediately. Do not stop using any medications without a doctor's advice.
LenalidomideAdalimumab
Severe
How does the drug interact with Lenated 10mg Capsule:
Using adalimumab and Lenated 10mg Capsule together may increase the risk of serious infections.

How to manage the interaction:
Co-administration of Lenated 10mg Capsule with Adalimumab can possibly result in an interaction, but it can be taken if your doctor has advised it. However, consult a doctor if you experience fever, chills, diarrhea, sore throat, muscle aches, difficulty breathing, weight loss, and pain or burning when you urinate. Do not discontinue any medications without consulting a doctor.
LenalidomideDesogestrel
Severe
How does the drug interact with Lenated 10mg Capsule:
Using Lenated 10mg Capsule together with Desogestrel may increase the risk of blood clots.

How to manage the interaction:
Although taking Desogestrel and Lenated 10mg Capsule together can evidently cause an interaction, it can be taken if your doctor has suggested it. if you experience any symptoms of blood clots such as chest pain, shortness of breath, difficulty breathing, coughing up blood, sudden loss of vision, and/or pain, redness or swelling in an arm or leg, consult the doctor immediately. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat a healthy diet and exercise regularly to maintain proper weight.

  • Avoid smoking and alcohol consumption.

  • Include food rich in iron, such as lean red meat, raisins, bell peppers, Brussel sprouts, and broccoli.

  • To prevent constipation, consume fibre-rich foods such as whole grains, broccoli, dried fruits, nuts, beans, apples, oranges, and pears. 

Habit Forming

No

Therapeutic Class

IMMUNOMODULATORS

Lenated 10mg Capsule Substitute

Substitutes safety advice
  • Lenangio 10 Capsule 10's

    by Others

    100.26per tablet
  • Lenalid 10 Capsule 30's

    by Others

    123.44per tablet
  • Laviat 10 mg Capsule 10's

    by Others

    132.57per tablet
  • Adlinod 10 Capsule 10's

    by Others

    203.80per tablet
  • Celomide 10 Capsule

    by Others

    153.00per tablet
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Alcohol

Unsafe

You are recommended to avoid alcohol consumption while taking Lenated 10mg Capsule as it might cause increased dizziness.

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Pregnancy

Unsafe

Lenated 10mg Capsule should not be taken during pregnancy as it causes severe birth defects or death to an unborn baby. Use highly effective contraception if you are a woman of child-bearing age. Inform your doctor if you are pregnant, think you are pregnant or planning for pregnancy.

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Breast Feeding

Unsafe

Avoid breastfeeding while taking Lenated 10mg Capsule as it is unknown if Lenated 10mg Capsule passes into breastmilk.

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Driving

Unsafe

Lenated 10mg Capsule may cause dizziness, sleepiness, and blurred vision. Do not drive or operate heavy machinery unless you are alert.

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Liver

Caution

Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Dose adjustment may be necessary. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Unsafe

Lenated 10mg Capsule is not recommended for children below 18years as the safety and effectiveness have not been established.

FAQs

Lenated 10mg Capsule is used to treat multiple myeloma, myelodysplastic syndromes, mantle cell lymphoma, and follicular lymphoma. It is also used to treat a type of myelodysplastic syndrome (MDS) known as deletion 5q MDS, where part of chromosome 5 is missing.

Lenated 10mg Capsule works by helping the body’s immune system and directly attacks cancer. It stops the development of cancer cells, stops the blood vessels growing in cancer, and stimulates the part of the immune system to attack the cancer cells.

Do not stop taking Lenated 10mg Capsule on your own. You are advised to take Lenated 10mg Capsule for as long as your doctor has prescribed it for you, depending on your medical condition. Do not be reluctant to speak with your doctor if you experience any difficulty while taking Lenated 10mg Capsule.

No, it is not safe to father a child while taking Lenated 10mg Capsule. Lenated 10mg Capsule can pass into human semen. During sexual activity with females of reproductive potential, always use effective contraception such as latex or synthetic condom while taking Lenated 10mg Capsule and for at least 4weeks after discontinuing Lenated 10mg Capsule, even if you have undergone a successful vasectomy. Male patients taking Lenated 10mg Capsule must not donate semen whilst taking Lenated 10mg Capsule and for 4weeks after discontinuing Lenated 10mg Capsule.

Patients taking Lenated 10mg Capsule must not donate blood during the treatment with Lenated 10mg Capsule and for 1month after discontinuation of Lenated 10mg Capsule as the donated blood might be given to pregnant women whose foetus should not be exposed to Lenated 10mg Capsule since it causes severe birth defects.

People with multiple myeloma taking Lenated 10mg Capsule may have an increased risk for blood clots in veins, arteries, and lungs. The risk is even higher if you are taking dexamethasone with Lenated 10mg Capsule for treating multiple myeloma. Consult your doctor immediately if you notice symptoms such as shortness of breath, chest pain, and swelling in the legs or arm.

Lenated 10mg Capsule might cause neutropenia (low white blood cells) or thrombocytopenia (low platelets). Blood count should be checked regularly during treatment with Lenated 10mg Capsule.

You should take Lenated 10mg Capsule at the same time every day. You can take the capsules with or without food.

Dose adjustment may be necessary. Please consult your doctor if you have kidney impairment or any concerns regarding this.

Some people treated with Lenated 10mg Capsule may rarely get other cancers. Consult your doctor for more details.

Yes, you will need to get regular blood tests while taking Lenated 10mg Capsule. Your doctor may suggest taking tests before and during treatment.

Yes, even women with fertility difficulties must take birth control while taking this medication. You must also take a negative pregnancy test 10 to 14 days before treatment and again 24 hours before. You will be tested for pregnancy every 2 to 4 weeks while on Lenated 10mg Capsule.

Lenated 10mg Capsule contains Lenalidomide as an active ingredient.

Common side effects of Lenated 10mg Capsule may include fatigue, constipation, diarrhoea, muscle cramps, nausea, headache, upper respiratory tract infection, dizziness, shortness of breath, and weakness. Talk with your doctor if you persistently experience any of these side effects.

Lenated 10mg Capsule should not be taken during pregnancy as it causes severe birth defects or death to an unborn baby. Use highly effective contraception if you are a woman of childbearing age. Inform your doctor if you are pregnant, think you are pregnant or planning for pregnancy.

Avoid breastfeeding while taking Lenated 10mg Capsule as it is unknown if Lenated 10mg Capsule passes into breastmilk.

Country of origin

India
Other Info - LE24598

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