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Written By Veda Maddala , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
Kabihep 25000IU Injection 5 ml is used to prevent and treat deep vein thrombosis (blood clots in leg veins), pulmonary embolism (blood clots in the lung), stroke, Transient ischaemic attack (TIA), and heart attacks. It contains Heparin, which works by inhibiting the production of fibrin (a protein that binds platelets together and forms a clot), preventing blood clot formation. Some people may experience haemorrhage (bleeding), thrombocytopenia (low platelets), hypersensitivity reactions, and elevations of liver enzyme (aminotransferase) levels. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Composition :

HEPARIN-25000IU

Manufacturer/Marketer :

Fresenius Kabi India Pvt Ltd

Consume Type :

PARENTERAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Kabihep 25000IU Injection 5 ml

Kabihep 25000IU Injection 5 ml belongs to a class of drugs called anticoagulants or blood thinners. Kabihep 25000IU Injection 5 ml is primarily used to prevent and treat deep vein thrombosis (blood clots in leg veins), pulmonary embolism (blood clots in the lung), stroke, Transient ischaemic attack (TIA), and heart attacks. Deep vein thrombosis is a medical condition in which blood clots form in deep veins, usually in the legs. Pulmonary embolism is a condition in which a blood clot blocks the arteries in the lungs. A stroke is a condition where a blood clot restricts the flow of blood to your brain, causing brain cells to die and possibly resulting in permanent brain damage or death. Transient ischaemic attack (TIA) is a condition also called mini-strokes. These have similar symptoms to a stroke, but the effects usually last less than 24 hours. Heart attack is a condition where a blood clot blocks a blood vessel supplying your heart, starving it of oxygen and causing chest pain and sometimes death.

Blood clots are formed to stop bleeding that occurs due to tissue injury. Though blood clots are useful to stop bleeding, they may be harmful when abnormally formed within blood vessels as they block blood vessels and inhibit blood flow to essential organs such as the brain, heart, or lungs. Kabihep 25000IU Injection 5 ml works by inhibiting the production of fibrin (a protein that binds platelets together and forms a clot), preventing blood clot formation.

Kabihep 25000IU Injection 5 ml will be administered by a healthcare professional; do not self-administer. Some people may experience haemorrhage, thrombocytopenia (low platelets), hypersensitivity reactions, and elevations of liver enzyme (aminotransferase) levels. Most of these side effects of Kabihep 25000IU Injection 5 ml do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are known to be allergic to Kabihep 25000IU Injection 5 ml or any other medicines, please tell your doctor. It is not known whether Kabihep 25000IU Injection 5 ml harms the baby or passes into breast milk in pregnancy and breastfeeding state. If you are pregnant or breastfeeding, it is advised to consult a doctor before using Kabihep 25000IU Injection 5 ml. Kabihep 25000IU Injection 5 ml is not recommended for children below 2 months of age. If you have diabetes, kidney or liver problems, bleeding problems, or are aged above 60 years, inform your doctor before taking Kabihep 25000IU Injection 5 ml.

Uses of Kabihep 25000IU Injection 5 ml

Prevention of blood clots.

Directions for Use

Kabihep 25000IU Injection 5 ml will be administered by a healthcare professional; do not self-administer.

Medicinal Benefits

Kabihep 25000IU Injection 5 ml is primarily used to prevent and treat blood clots by inhibiting the production of fibrin (a protein that binds platelets together and forms a clot). Kabihep 25000IU Injection 5 ml also reduces the risk of blood clots during surgeries (like heart surgery). Kabihep 25000IU Injection 5 ml is used as an anticoagulant in blood transfusion and in a dialysis procedure.

How Kabihep 25000IU Injection 5 ml Works

Kabihep 25000IU Injection 5 ml works by inhibiting the production of fibrin (a protein that binds platelets together and forms a clot), preventing blood clot formation.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Kabihep 25000IU Injection 5 ml

  • Red itchy patches or lumps at the site of injection
  • Unusual bleeding
  • Skin redness

What if I have taken an overdose of Kabihep 25000IU Injection 5 ml

The overdose of Kabihep 25000IU Injection 5 ml is unlikely as it is administered by a doctor. Too much heparin may cause bleeding. Therefore, if you suspect any adverse reactions or unusual symptoms or more severe bleeding while on treatment with Kabihep 25000IU Injection 5 ml, please inform your doctor immediately.

Drug Warnings

Use Kabihep 25000IU Injection 5 ml cautiously in conditions with increased risk of bleeding. Use of name contraindicated in patients with HIT - Heparin-induced thrombosis (the abnormal formation of blood clots inside a blood vessel) and HITT (heparin-induced thrombocytopenia and thrombosis) might occur. Monitoring of blood coagulation tests like platelet count and haematocrit should be done in all patients receiving Kabihep 25000IU Injection 5 ml. Patients should inform the doctor that they are receiving Kabihep 25000IU Injection 5 ml before any surgery is scheduled.

Drug-Drug Interactions

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HeparinBazedoxifene
Critical
HeparinMifepristone
Critical

Drug-Drug Interactions

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HeparinBazedoxifene
Critical
How does the drug interact with Kabihep 25000IU Injection 5 ml:
When Kabihep 25000IU Injection 5 ml is taken with bazedoxifene the effects of Kabihep 25000IU Injection 5 ml are reduced by bazedoxifene.

How to manage the interaction:
Taking Bazedoxifene with Kabihep 25000IU Injection 5 ml is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without a doctor's advice.
HeparinMifepristone
Critical
How does the drug interact with Kabihep 25000IU Injection 5 ml:
Taking Mifepristone with Kabihep 25000IU Injection 5 ml can increase the risk of negative side effects.

How to manage the interaction:
Taking Kabihep 25000IU Injection 5 ml with Mifepristone is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without a doctor's advice.
HeparinAlteplase
Critical
How does the drug interact with Kabihep 25000IU Injection 5 ml:
Taking Alteplase with Kabihep 25000IU Injection 5 ml can increase the risk of bleeding.

How to manage the interaction:
Taking Kabihep 25000IU Injection 5 ml with Alteplase is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, if you have unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
HeparinTenecteplase
Critical
How does the drug interact with Kabihep 25000IU Injection 5 ml:
Taking Tenecteplase with Kabihep 25000IU Injection 5 ml can increase the risk of bleeding.

How to manage the interaction:
Taking Kabihep 25000IU Injection 5 ml with Tenecteplase is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, if you notice unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
HeparinTiclopidine
Critical
How does the drug interact with Kabihep 25000IU Injection 5 ml:
Taking Ticlopidine with Kabihep 25000IU Injection 5 ml can increase the risk of bleeding.

How to manage the interaction:
Taking Ticlopidine with Kabihep 25000IU Injection 5 ml is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without a doctor's advice.
HeparinOritavancin
Critical
How does the drug interact with Kabihep 25000IU Injection 5 ml:
Using Kabihep 25000IU Injection 5 ml with Oritavancin can make Kabihep 25000IU Injection 5 ml less effective as a therapy.

How to manage the interaction:
Kabihep 25000IU Injection 5 ml is not recommended within 120 hours (5 days) of taking oritavancin. Oritavancin can interfere with certain of the major coagulation tests used to assess Kabihep 25000IU Injection 5 ml's effectiveness and safety, it can be taken only if prescribed by a doctor. Do not discontinue any medications without a doctor's advice.
HeparinFondaparinux
Severe
How does the drug interact with Kabihep 25000IU Injection 5 ml:
Taking fondaparinux with Kabihep 25000IU Injection 5 ml can increase the risk of bleeding.

How to manage the interaction:
Taking Fondaparinux with Kabihep 25000IU Injection 5 ml together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without a doctor's advice.
HeparinBivalirudin
Severe
How does the drug interact with Kabihep 25000IU Injection 5 ml:
Taking Bivalirudin with Kabihep 25000IU Injection 5 ml may increase the risk of bleeding.

How to manage the interaction:
Although taking Bivalirudin and Kabihep 25000IU Injection 5 ml together can cause an interaction, it can be taken if a doctor has suggested it. However, if you have unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
HeparinCangrelor
Severe
How does the drug interact with Kabihep 25000IU Injection 5 ml:
Co-administration of Cangrelor with Kabihep 25000IU Injection 5 ml can increase the risk of bleeding leading to serious blood loss.

How to manage the interaction:
Although there is a possible interaction between Kabihep 25000IU Injection 5 ml and Cangrelor, you can take these medicines together if prescribed by a doctor. However, if you have any unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, you should seek immediate medical attention. Do not stop using any medications without a doctor's advice.
HeparinDicoumarol
Severe
How does the drug interact with Kabihep 25000IU Injection 5 ml:
Coadministration of Kabihep 25000IU Injection 5 ml and dicumarol may increase the risk of bleeding.

How to manage the interaction:
Although taking Kabihep 25000IU Injection 5 ml and Dicoumarol together can cause an interaction, it can be taken if a doctor has suggested it. However, if you have unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness, contact a doctor immediately. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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HEPARIN-25000IUHerbal products/medicines
Moderate

Drug-Food Interactions

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HEPARIN-25000IUHerbal products/medicines
Moderate
Common Foods to Avoid:
Garlic Pill

How to manage the interaction:
Taking Kabihep 25000IU Injection 5 ml along with herbs and supplements such as garlic, ginger, bilberry, danshen, piracetam, and ginkgo biloba can lead to an increased risk of bleeding Avoid taking herbs and supplements such as garlic, ginger, bilberry, danshen, piracetam, and ginkgo biloba while taking Kabihep 25000IU Injection 5 ml.

Habit Forming

No

Therapeutic Class

ANTICOAGULANTS / ANTITHROMBOTICS. ANTICONVULSANTS

Kabihep 25000IU Injection 5 ml Substitute

Substitutes safety advice
  • Caprin 25000IU Injection 5 ml

    59.04per tablet
  • Beparine 25000IU Injection 1's

    302.00per tablet
  • Hepaglan-25 Injection 5 ml

    by AYUR

    60.30per tablet
  • Reniparin 25000 Iu Inj

    by AYUR

    305.10per tablet
  • Rinhepa 25K/5Ml Inj

    by AYUR

    58.96per tablet
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Alcohol

Caution

You are recommended to avoid consumption of alcohol with Kabihep 25000IU Injection 5 ml as it may cause severe bleeding in the stomach and harmful side effects to the liver.

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Pregnancy

Caution

Kabihep 25000IU Injection 5 ml is a Category C pregnancy drug and should be given to pregnant women only if clearly needed and has more benefits than risks. Preservative-free forms are preferred in pregnant women as preservatives such as benzyl alcohol may cross the placenta.

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Breast Feeding

Caution

Kabihep 25000IU Injection 5 ml should be given to breastfeeding mothers only if clearly needed and has more benefits than risks.

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Driving

Safe if prescribed

Kabihep 25000IU Injection 5 ml usually does not affect your ability to drive or operate machinery.

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Liver

Caution

Kabihep 25000IU Injection 5 ml should be given with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Kidney

Caution

Kabihep 25000IU Injection 5 ml should be given with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.

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Children

Caution

Kabihep 25000IU Injection 5 ml is not recommended for children below 2 months.

FAQs

Kabihep 25000IU Injection 5 ml is used to prevent and treat deep vein thrombosis (blood clots in leg veins), pulmonary embolism (blood clots in the lung), stroke, Transient ischaemic attack (TIA), and heart attacks.
Kabihep 25000IU Injection 5 ml works by inhibiting the production of fibrin (a protein that binds platelets together and forms a clot). Thereby, preventing blood clot formation.
No, you are not recommended to take ibuprofen with Kabihep 25000IU Injection 5 ml as co-administration of these two medicines may increase the risk of bleeding more easily. However, please consult a doctor before taking other medicines with Kabihep 25000IU Injection 5 ml.
Yes, Kabihep 25000IU Injection 5 ml may increase potassium levels in the blood (hyperkalaemia), especially when given for a long period. Therefore, it is advised to inform your doctor if you are taking any medicines that increase potassium levels in the blood.
Yes, Kabihep 25000IU Injection 5 ml may cause bleeding. If you notice purple spots on the skin or unusual bruising, blood in urine, black tarry stools, unusual bleeding from gums or nose, please inform your doctor immediately as these are signs of bleeding more easily.
Yes, Kabihep 25000IU Injection 5 ml may cause allergic reactions such as fever, chills, difficulty in breathing, wheezing, blue shade to the lips, swelling of lips, and eyes. It is not necessary for everyone taking Kabihep 25000IU Injection 5 ml to experience an allergic reaction. However, if you notice any of these signs, please inform your doctor immediately.

Country of origin

India

Manufacturer/Marketer address

Fresenius Kabi Ag , Else-Krã¶Ner-Straãÿe 1 , 61352 Bad Homburg , Germany
Other Info - KAB0042

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