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Written By Veda Maddala , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
Rinhepa 25K/5Ml Inj is used to prevent and treat deep vein thrombosis (blood clots in leg veins), pulmonary embolism (blood clots in the lung), stroke, Transient ischaemic attack (TIA), and heart attacks. It contains Heparin, which works by inhibiting the production of fibrin (a protein that binds platelets together and forms a clot), preventing blood clot formation. Some people may experience haemorrhage (bleeding), thrombocytopenia (low platelets), hypersensitivity reactions, and elevations of liver enzyme (aminotransferase) levels. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Composition :

HEPARIN-25000IU

Manufacturer/Marketer :

United Biotech Pvt Ltd

Consume Type :

PARENTERAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Rinhepa 25K/5Ml Inj

Rinhepa 25K/5Ml Inj belongs to a class of drugs called anticoagulants or blood thinners. Rinhepa 25K/5Ml Inj is primarily used to prevent and treat deep vein thrombosis (blood clots in leg veins), pulmonary embolism (blood clots in the lung), stroke, Transient ischaemic attack (TIA), and heart attacks. Deep vein thrombosis is a medical condition in which blood clots form in deep veins, usually in the legs. Pulmonary embolism is a condition in which a blood clot blocks the arteries in the lungs. A stroke is a condition where a blood clot restricts the flow of blood to your brain, causing brain cells to die and possibly resulting in permanent brain damage or death. Transient ischaemic attack (TIA) is a condition also called mini-strokes. These have similar symptoms to a stroke, but the effects usually last less than 24 hours. Heart attack is a condition where a blood clot blocks a blood vessel supplying your heart, starving it of oxygen and causing chest pain and sometimes death.

Blood clots are formed to stop bleeding that occurs due to tissue injury. Though blood clots are useful to stop bleeding, they may be harmful when abnormally formed within blood vessels as they block blood vessels and inhibit blood flow to essential organs such as the brain, heart, or lungs. Rinhepa 25K/5Ml Inj works by inhibiting the production of fibrin (a protein that binds platelets together and forms a clot), preventing blood clot formation.

Rinhepa 25K/5Ml Inj will be administered by a healthcare professional; do not self-administer. Some people may experience haemorrhage, thrombocytopenia (low platelets), hypersensitivity reactions, and elevations of liver enzyme (aminotransferase) levels. Most of these side effects of Rinhepa 25K/5Ml Inj do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are known to be allergic to Rinhepa 25K/5Ml Inj or any other medicines, please tell your doctor. It is not known whether Rinhepa 25K/5Ml Inj harms the baby or passes into breast milk in pregnancy and breastfeeding state. If you are pregnant or breastfeeding, it is advised to consult a doctor before using Rinhepa 25K/5Ml Inj. Rinhepa 25K/5Ml Inj is not recommended for children below 2 months of age. If you have diabetes, kidney or liver problems, bleeding problems, or are aged above 60 years, inform your doctor before taking Rinhepa 25K/5Ml Inj.

Uses of Rinhepa 25K/5Ml Inj

Prevention of blood clots.

Directions for Use

Rinhepa 25K/5Ml Inj will be administered by a healthcare professional; do not self-administer.

Medicinal Benefits

Rinhepa 25K/5Ml Inj is primarily used to prevent and treat blood clots by inhibiting the production of fibrin (a protein that binds platelets together and forms a clot). Rinhepa 25K/5Ml Inj also reduces the risk of blood clots during surgeries (like heart surgery). Rinhepa 25K/5Ml Inj is used as an anticoagulant in blood transfusion and in a dialysis procedure.

How Rinhepa 25K/5Ml Inj Works

Rinhepa 25K/5Ml Inj works by inhibiting the production of fibrin (a protein that binds platelets together and forms a clot), preventing blood clot formation.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Rinhepa 25K/5Ml Inj

  • Red itchy patches or lumps at the site of injection
  • Unusual bleeding
  • Skin redness

What if I have taken an overdose of Rinhepa 25K/5Ml Inj

The overdose of Rinhepa 25K/5Ml Inj is unlikely as it is administered by a doctor. Too much heparin may cause bleeding. Therefore, if you suspect any adverse reactions or unusual symptoms or more severe bleeding while on treatment with Rinhepa 25K/5Ml Inj, please inform your doctor immediately.

Drug Warnings

Use Rinhepa 25K/5Ml Inj cautiously in conditions with increased risk of bleeding. Use of name contraindicated in patients with HIT - Heparin-induced thrombosis (the abnormal formation of blood clots inside a blood vessel) and HITT (heparin-induced thrombocytopenia and thrombosis) might occur. Monitoring of blood coagulation tests like platelet count and haematocrit should be done in all patients receiving Rinhepa 25K/5Ml Inj. Patients should inform the doctor that they are receiving Rinhepa 25K/5Ml Inj before any surgery is scheduled.

Drug-Drug Interactions

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HeparinBazedoxifene
Critical
HeparinAlteplase
Critical

Drug-Drug Interactions

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HeparinBazedoxifene
Critical
How does the drug interact with Rinhepa 25K/5Ml Inj:
When Rinhepa 25K/5Ml Inj is taken with bazedoxifene the effects of Rinhepa 25K/5Ml Inj are reduced by bazedoxifene.

How to manage the interaction:
Taking Bazedoxifene with Rinhepa 25K/5Ml Inj is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without a doctor's advice.
HeparinAlteplase
Critical
How does the drug interact with Rinhepa 25K/5Ml Inj:
Taking Alteplase with Rinhepa 25K/5Ml Inj can increase the risk of bleeding.

How to manage the interaction:
Taking Rinhepa 25K/5Ml Inj with Alteplase is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, if you have unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
HeparinTiclopidine
Critical
How does the drug interact with Rinhepa 25K/5Ml Inj:
Taking Ticlopidine with Rinhepa 25K/5Ml Inj can increase the risk of bleeding.

How to manage the interaction:
Taking Ticlopidine with Rinhepa 25K/5Ml Inj is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without a doctor's advice.
HeparinTenecteplase
Critical
How does the drug interact with Rinhepa 25K/5Ml Inj:
Taking Tenecteplase with Rinhepa 25K/5Ml Inj can increase the risk of bleeding.

How to manage the interaction:
Taking Rinhepa 25K/5Ml Inj with Tenecteplase is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, if you notice unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
HeparinMifepristone
Critical
How does the drug interact with Rinhepa 25K/5Ml Inj:
Taking Mifepristone with Rinhepa 25K/5Ml Inj can increase the risk of negative side effects.

How to manage the interaction:
Taking Rinhepa 25K/5Ml Inj with Mifepristone is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without a doctor's advice.
HeparinOritavancin
Critical
How does the drug interact with Rinhepa 25K/5Ml Inj:
Using Rinhepa 25K/5Ml Inj with Oritavancin can make Rinhepa 25K/5Ml Inj less effective as a therapy.

How to manage the interaction:
Rinhepa 25K/5Ml Inj is not recommended within 120 hours (5 days) of taking oritavancin. Oritavancin can interfere with certain of the major coagulation tests used to assess Rinhepa 25K/5Ml Inj's effectiveness and safety, it can be taken only if prescribed by a doctor. Do not discontinue any medications without a doctor's advice.
HeparinEnoxaparin
Severe
How does the drug interact with Rinhepa 25K/5Ml Inj:
Taking Rinhepa 25K/5Ml Inj with Enoxaparin may increase the risk of bleeding.

How to manage the interaction:
There may be a possibility of interaction between Rinhepa 25K/5Ml Inj and Enoxaparin, but it can be taken if prescribed by a doctor. However, consult a doctor, if you experience any unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness. Do not stop using any medications without a doctor's advice.
HeparinCefpodoxime
Severe
How does the drug interact with Rinhepa 25K/5Ml Inj:
Co-administration of Cefpodoxime with Rinhepa 25K/5Ml Inj may enhance the levels or effects of Rinhepa 25K/5Ml Inj by anticoagulation (preventing blood from clotting).

How to manage the interaction:
Although there is an interaction, Cefpodoxime can be taken with Rinhepa 25K/5Ml Inj if prescribed by the doctor. Do not stop using any medications without a doctor's advice. Do not discontinue the medication without consulting a doctor.
HeparinUrokinase
Severe
How does the drug interact with Rinhepa 25K/5Ml Inj:
Taking Rinhepa 25K/5Ml Inj with Urokinase can increase the risk of bleeding.

How to manage the interaction:
Co-administration of Rinhepa 25K/5Ml Inj with Urokinase can result in an interaction, but it can be taken if a doctor has advised it. However, if you have unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
HeparinKetorolac
Severe
How does the drug interact with Rinhepa 25K/5Ml Inj:
Coadministration of Ketorolac with Rinhepa 25K/5Ml Inj can increase the risk of bleeding.

How to manage the interaction:
There may be a possibility of interaction between Ketorolac and Rinhepa 25K/5Ml Inj, but it can be taken if prescribed by a doctor. However, if you experience any unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness, call a doctor immediately. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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HEPARIN-25000IUHerbal products/medicines
Moderate

Drug-Food Interactions

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HEPARIN-25000IUHerbal products/medicines
Moderate
Common Foods to Avoid:
Garlic Pill

How to manage the interaction:
Taking Rinhepa 25K/5Ml Inj along with herbs and supplements such as garlic, ginger, bilberry, danshen, piracetam, and ginkgo biloba can lead to an increased risk of bleeding Avoid taking herbs and supplements such as garlic, ginger, bilberry, danshen, piracetam, and ginkgo biloba while taking Rinhepa 25K/5Ml Inj.

Habit Forming

No

Therapeutic Class

ANTICOAGULANTS / ANTITHROMBOTICS. ANTICONVULSANTS

Rinhepa 25K/5Ml Inj Substitute

Substitutes safety advice
  • Caprin 25000IU Injection 5 ml

    59.04per tablet
  • Beparine 25000IU Injection 1's

    302.00per tablet
  • Stanhep-25000IU Injection 5 ml

    61.56per tablet
  • Hepaglan-25 Injection 5 ml

    by AYUR

    60.30per tablet
  • Reniparin 25000 Iu Inj

    by AYUR

    305.10per tablet
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Alcohol

Caution

You are recommended to avoid consumption of alcohol with Rinhepa 25K/5Ml Inj as it may cause severe bleeding in the stomach and harmful side effects to the liver.

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Pregnancy

Caution

Rinhepa 25K/5Ml Inj is a Category C pregnancy drug and should be given to pregnant women only if clearly needed and has more benefits than risks. Preservative-free forms are preferred in pregnant women as preservatives such as benzyl alcohol may cross the placenta.

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Breast Feeding

Caution

Rinhepa 25K/5Ml Inj should be given to breastfeeding mothers only if clearly needed and has more benefits than risks.

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Driving

Safe if prescribed

Rinhepa 25K/5Ml Inj usually does not affect your ability to drive or operate machinery.

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Liver

Caution

Rinhepa 25K/5Ml Inj should be given with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Kidney

Caution

Rinhepa 25K/5Ml Inj should be given with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.

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Children

Caution

Rinhepa 25K/5Ml Inj is not recommended for children below 2 months.

FAQs

Rinhepa 25K/5Ml Inj is used to prevent and treat deep vein thrombosis (blood clots in leg veins), pulmonary embolism (blood clots in the lung), stroke, Transient ischaemic attack (TIA), and heart attacks.
Rinhepa 25K/5Ml Inj works by inhibiting the production of fibrin (a protein that binds platelets together and forms a clot). Thereby, preventing blood clot formation.
No, you are not recommended to take ibuprofen with Rinhepa 25K/5Ml Inj as co-administration of these two medicines may increase the risk of bleeding more easily. However, please consult a doctor before taking other medicines with Rinhepa 25K/5Ml Inj.
Yes, Rinhepa 25K/5Ml Inj may increase potassium levels in the blood (hyperkalaemia), especially when given for a long period. Therefore, it is advised to inform your doctor if you are taking any medicines that increase potassium levels in the blood.
Yes, Rinhepa 25K/5Ml Inj may cause bleeding. If you notice purple spots on the skin or unusual bruising, blood in urine, black tarry stools, unusual bleeding from gums or nose, please inform your doctor immediately as these are signs of bleeding more easily.
Yes, Rinhepa 25K/5Ml Inj may cause allergic reactions such as fever, chills, difficulty in breathing, wheezing, blue shade to the lips, swelling of lips, and eyes. It is not necessary for everyone taking Rinhepa 25K/5Ml Inj to experience an allergic reaction. However, if you notice any of these signs, please inform your doctor immediately.

Country of origin

India

Manufacturer/Marketer address

FC/B-1 (Extn.), Mohan Co-operative Industrial Estate Mathura Road, New Delhi - 110 044
Other Info - RIN0162

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