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Written By Veda Maddala , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
Last Updated Oct 9, 2024 | 12:40 PM IST
Hepakal 25000 IU Injection is used to prevent and treat deep vein thrombosis (blood clots in leg veins), pulmonary embolism (blood clots in the lung), stroke, Transient ischaemic attack (TIA), and heart attacks. It contains Heparin, which works by inhibiting the production of fibrin (a protein that binds platelets together and forms a clot), preventing blood clot formation. Some people may experience haemorrhage (bleeding), thrombocytopenia (low platelets), hypersensitivity reactions, and elevations of liver enzyme (aminotransferase) levels. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Composition

HEPARIN-25000IU

Consume Type

PARENTERAL

Return Policy

Not Returnable

for this medicine

About Hepakal 25000 IU Injection

Hepakal 25000 IU Injection belongs to a class of drugs called anticoagulants or blood thinners. Hepakal 25000 IU Injection is primarily used to prevent and treat deep vein thrombosis (blood clots in leg veins), pulmonary embolism (blood clots in the lung), stroke, Transient ischaemic attack (TIA), and heart attacks. Deep vein thrombosis is a medical condition in which blood clots form in deep veins, usually in the legs. Pulmonary embolism is a condition in which a blood clot blocks the arteries in the lungs. A stroke is a condition where a blood clot restricts the flow of blood to your brain, causing brain cells to die and possibly resulting in permanent brain damage or death. Transient ischaemic attack (TIA) is a condition also called mini-strokes. These have similar symptoms to a stroke, but the effects usually last less than 24 hours. Heart attack is a condition where a blood clot blocks a blood vessel supplying your heart, starving it of oxygen and causing chest pain and sometimes death.

Blood clots are formed to stop bleeding that occurs due to tissue injury. Though blood clots are useful to stop bleeding, they may be harmful when abnormally formed within blood vessels as they block blood vessels and inhibit blood flow to essential organs such as the brain, heart, or lungs. Hepakal 25000 IU Injection works by inhibiting the production of fibrin (a protein that binds platelets together and forms a clot), preventing blood clot formation.

Hepakal 25000 IU Injection will be administered by a healthcare professional; do not self-administer. Some people may experience haemorrhage, thrombocytopenia (low platelets), hypersensitivity reactions, and elevations of liver enzyme (aminotransferase) levels. Most of these side effects of Hepakal 25000 IU Injection do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are known to be allergic to Hepakal 25000 IU Injection or any other medicines, please tell your doctor. It is not known whether Hepakal 25000 IU Injection harms the baby or passes into breast milk in pregnancy and breastfeeding state. If you are pregnant or breastfeeding, it is advised to consult a doctor before using Hepakal 25000 IU Injection. Hepakal 25000 IU Injection is not recommended for children below 2 months of age. If you have diabetes, kidney or liver problems, bleeding problems, or are aged above 60 years, inform your doctor before taking Hepakal 25000 IU Injection.

Uses of Hepakal 25000 IU Injection

Prevention of blood clots.

Medicinal Benefits

Hepakal 25000 IU Injection is primarily used to prevent and treat blood clots by inhibiting the production of fibrin (a protein that binds platelets together and forms a clot). Hepakal 25000 IU Injection also reduces the risk of blood clots during surgeries (like heart surgery). Hepakal 25000 IU Injection is used as an anticoagulant in blood transfusion and in a dialysis procedure.

Directions for Use

Hepakal 25000 IU Injection will be administered by a healthcare professional; do not self-administer.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Hepakal 25000 IU Injection

  • Red itchy patches or lumps at the site of injection
  • Unusual bleeding
  • Skin redness

Drug Warnings

Use Hepakal 25000 IU Injection cautiously in conditions with increased risk of bleeding. Use of name contraindicated in patients with HIT - Heparin-induced thrombosis (the abnormal formation of blood clots inside a blood vessel) and HITT (heparin-induced thrombocytopenia and thrombosis) might occur. Monitoring of blood coagulation tests like platelet count and haematocrit should be done in all patients receiving Hepakal 25000 IU Injection. Patients should inform the doctor that they are receiving Hepakal 25000 IU Injection before any surgery is scheduled.

Drug Interactions

Drug-Drug Interaction: Hepakal 25000 IU Injection may have interaction with pain killers (salicylic acid, ibuprofen, indomethacin, phenylbutazone, and celecoxib), dextran, anti-malarial (hydroxychloroquine), blood thinner (abciximab, eptifibatide, dipyridamole), heart medicines (digitalis), antibiotic (tetracycline), nicotine, antiallergics, or blood pressure-lowering pills (nitroglycerin)

Drug-Food Interaction: Hepakal 25000 IU Injection may interact with alcohol. Avoid foods rich in vitamin K like coriander, cabbage, spinach, broccoli, collard greens, kale (leaf cabbage), black liquorice, turnip greens, avocados, brussels sprouts as they may affect the working of Hepakal 25000 IU Injection. It is advisable to avoid smoking and use of tobacco products and nicotine as they may reduce the effectiveness of Hepakal 25000 IU Injection.

Drug-Disease Interaction: Use with caution in patients with bleeding problems, low platelet count (thrombocytopenia) and thrombosis (blood clot in veins).

Drug-Drug Interactions Checker List

  • SALICYLIC ACID
  • IBUPROFEN
  • INDOMETHACIN
  • PHENYLBUTAZONE
  • CELECOXIB
  • HYDROXYCHLOROQUINE
  • ABCIXIMAB
  • DIPYRIDAMOLE
  • DIGITALIS
  • TETRACYCLINE
  • NITROGLYCERIN

Habit Forming

No

Special Advise

Regular blood tests are advised while taking Hepakal 25000 IU Injection to monitor prothrombin, platelets and coagulation time on regular basis.

Disease/Condition Glossary

Deep vein thrombosis (blood clots in legs) is a medical condition in which blood clots form in deep veins usually in the legs. The symptoms include leg pain or swelling.

Pulmonary embolism (blood clots in the lung) is a condition that occurs as the blood clots break and travel to the lungs from deep veins in the legs or other parts of the body. The symptoms of pulmonary embolism include chest pain, cough, and shortness of breath. 

Stroke is a condition where a blood clot restricts the flow of blood to your brain, causing brain cells to die and possibly resulting in permanent brain damage or death.

Transient ischaemic attack (TIA) is a condition also called 'mini-strokes', these have similar symptoms to a stroke, but the effects usually last less than 24 hours.

Heart attack is a condition where a blood clot blocks a blood vessel supplying your heart, starving it of oxygen and causing chest pain and sometimes death. Quick medication is advised to reduce the risk of serious conditions due to blood clots.

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Alcohol

Caution

You are recommended to avoid consumption of alcohol with Hepakal 25000 IU Injection as it may cause severe bleeding in the stomach and harmful side effects to the liver.

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Pregnancy

Caution

Hepakal 25000 IU Injection is a Category C pregnancy drug and should be given to pregnant women only if clearly needed and has more benefits than risks. Preservative-free forms are preferred in pregnant women as preservatives such as benzyl alcohol may cross the placenta.

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Breast Feeding

Caution

Hepakal 25000 IU Injection should be given to breastfeeding mothers only if clearly needed and has more benefits than risks.

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Driving

Safe if prescribed

Hepakal 25000 IU Injection usually does not affect your ability to drive or operate machinery.

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Liver

Caution

Hepakal 25000 IU Injection should be given with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Kidney

Caution

Hepakal 25000 IU Injection should be given with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.

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Children

Caution

Hepakal 25000 IU Injection is not recommended for children below 2 months.

Manufacturer/Marketer address

No. 47, Phase 3, Ashish Royal Park, Opposite Rohilkhand Dental & Medical College, Pilibhit By Pass, Bareilly-243006, Uttar Pradesh, India
Other Info - HE59837

Author Details

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FAQs

Hepakal 25000 IU Injection is used to prevent and treat deep vein thrombosis (blood clots in leg veins), pulmonary embolism (blood clots in the lung), stroke, Transient ischaemic attack (TIA), and heart attacks.
Hepakal 25000 IU Injection works by inhibiting the production of fibrin (a protein that binds platelets together and forms a clot). Thereby, preventing blood clot formation.
No, you are not recommended to take ibuprofen with Hepakal 25000 IU Injection as co-administration of these two medicines may increase the risk of bleeding more easily. However, please consult a doctor before taking other medicines with Hepakal 25000 IU Injection.
Yes, Hepakal 25000 IU Injection may increase potassium levels in the blood (hyperkalaemia), especially when given for a long period. Therefore, it is advised to inform your doctor if you are taking any medicines that increase potassium levels in the blood.
Yes, Hepakal 25000 IU Injection may cause bleeding. If you notice purple spots on the skin or unusual bruising, blood in urine, black tarry stools, unusual bleeding from gums or nose, please inform your doctor immediately as these are signs of bleeding more easily.
Yes, Hepakal 25000 IU Injection may cause allergic reactions such as fever, chills, difficulty in breathing, wheezing, blue shade to the lips, swelling of lips, and eyes. It is not necessary for everyone taking Hepakal 25000 IU Injection to experience an allergic reaction. However, if you notice any of these signs, please inform your doctor immediately.

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