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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Jan 1, 2025 | 2:50 PM IST
Clarinova-250 Tablet is used to treat a wide range of bacterial infections, including chest infections such as bronchitis and pneumonia, skin problems such as cellulitis (potentially serious bacterial skin infection, the affected skin appears swollen and red and is typically painful and warm to the touch), and ear infections. Besides this, it is also used in combination with other medicines to treat duodenal ulcers caused by H. pylori. It contains Clarithromycin, which inhibits the growth of bacteria. It may cause some common side effects, such as nausea, diarrhoea, vomiting, loss of appetite, bloating, indigestion, headaches and difficulty sleeping. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Manufacturer/Marketer :

Mankind Pharma Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

Jan-27

About Clarinova-250 Tablet

Clarinova-250 Tablet is used to treat a wide range of bacterial infections, including chest infections such as bronchitis and pneumonia, skin problems such as cellulitis (potentially serious bacterial skin infection, the affected skin appears swollen and red and is typically painful and warm to the touch), and ear infections. Besides this, Clarinova-250 Tablet is also used in combination with other medicines to treat duodenal ulcers caused by H. pylori.

Clarinova-250 Tablet contains Clarithromycin (antibiotic). It inhibits the protein synthesis process required for the growth of the bacterial cell. As a result, bacterial cells are not able to reproduce and grow. Thus, Clarinova-250 Tablet helps prevent infections.

Clarinova-250 Tablet should only be if your doctor has prescribed you. Clarinova-250 Tablet should not be stopped even if you feel better as it is an antibiotic medication, and completing the full course is necessary; otherwise, the infection might re-appear in a more severe form. Like all medicines, Clarinova-250 Tablet may cause some common side effects, including feeling sick (nausea), diarrhoea and being sick (vomiting), losing your appetite, bloating and indigestion, headaches and difficulty sleeping. These side effects are temporary and may get resolved after some time; however, if this side persists, let your doctor know about this if you notice any sudden wheeziness, tightness in the chest or throat, difficulty in breathing, swelling of the eyelids, face or lips, rash or itching (especially affecting your whole body) STOP TAKING your medicine and go to a doctor immediately.

Do not take Clarinova-250 Tablet if allergic to azithromycin, other macrolide antibiotics, or any components present in Clarinova-250 Tablet. Clarinova-250 Tablet isn't normally recommended during pregnancy and while breastfeeding. But your doctor may prescribe it if the benefits of taking it are greater than the risks. Do not consume alcohol as it may cause excessive drowsiness when taken along with Clarinova-250 Tablet. Before using the Clarinova-250 Tablet, tell your doctor if you ever had an allergy to Clarinova-250 Tablet have kidney problems, liver problems, swollen food pipe (oesophagitis), lupus disease (an autoimmune disease), or muscle disease (myasthenia gravis). Do not drink alcohol with Clarinova-250 Tablet as it may increase the unpleasant side effects like drowsiness and dizziness.

Uses of Clarinova-250 Tablet

Treatment of Bacterial infections

Medicinal Benefits

Clarinova-250 Tablet is a type of macrolide class of antibiotic which is effective against a wide range of bacteria, including gram-negative and gram-positive bacteria, anaerobes, and some parasites (like Balantidium coli and Entamoeba species). It is prescribed for treating various bacterial infections, including chest infections such as pneumonia, skin problems such as cellulitis, and ear infections; on the other hand, It is also used in combination with other medicines to treat duodenal ulcers caused by H. pylori (Helicobacter pylori). Clarinova-250 Tablet is sometimes used by people who have an allergy to penicillin and antibiotics similar to penicillin, such as amoxicillin.

Side Effects of Clarinova-250 Tablet

  • Headache

  • Diarrhoea

  • Being sick (vomiting)

  • Nausea (feeling sick)

  • Loss of appetite

  • Taste change

  • Bloating

  • Indigestion

  • Abdominal pain

  • Insomnia (difficulty sleeping)

Directions for Use

Tablet/capsule: Swallow it as a whole with water; do not crush, break or chew it.Dispersible Tablet: Check the label for directions before use. Disperse the tablet in the prescribed amount of water and swallow the contents. Do not crush, chew or swallow as a whole.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Iron and antacid (like magnesium hydroxide and aluminium hydroxide) may bind to Clarinova-250 Tablet in the gastrointestinal tract, lowering its efficiency. So, a gap of at least 2 hours should be maintained between intake of Clarinova-250 Tablet and iron supplements and antacids. Besides this, in some cases, the use of Clarinova-250 Tablet causes antibiotic-associated diarrhoea. Clarinova-250 Tablet may cause sensitive skin to sunlight and ultraviolet rays, causing an exaggerated sunburn reaction. Hence it is advisable to apply sunscreen before going outside. Its use has also been associated with an increased risk of fungal skin infections like (vaginal candidiasis - thrush). Tetracycline and Clarinova-250 Tablet can form a stable calcium complex in bone-forming tissue, thereby affecting the growth of fibula bones in young children and bone development in the foetus. Using a Clarinova-250 Tablet with isotretinoin should be avoided as it has been reported to cause pseudotumor cerebri (increased pressure inside the brain). Long-term use of Clarinova-250 Tablet may affect your blood, kidney, and liver health, so yearly diagnostics test of these parameters is recommended.

Therapeutic Class

ANTI- BACTERIALS

Drug-Drug Interactions

verifiedApollotooltip
ClarithromycinAstemizole
Critical
ClarithromycinNaloxegol
Critical

Drug-Food Interactions

verifiedApollotooltip
CLARITHROMYCIN-250MGGrapefruit and Grapefruit Juice
Mild

Diet & Lifestyle Advise

  • Probiotics and prebiotics can also help to reduce the side effects of antibiotics.

  • Include more fibre-enriched food in your diet, as it can be easily digested by your gut bacteria, which helps stimulate their growth. Thus, fibre foods may help restore healthy gut bacteria after a course of antibiotics. Whole grains like whole-grain bread and brown rice should be included in your diet. 

  • Eating grapefruit during antibiotics treatment can prevent the body from utilizing Clarinova-250 Tablet properly. So, avoid intake of grapefruit or grapefruit juice with the antibiotic. 

  • Avoid taking too much calcium, iron-enriched foods and drinks as it might affect the working of Clarinova-250 Tablet. 

  • Avoid intake of alcoholic beverages with Clarinova-250 Tablet as it can make you dehydrated and affect your sleep. This can make it harder for your body to aid the Clarinova-250 Tablet in fighting off infections.

Habit Forming

No

How Clarinova-250 Tablet Works

Clarinova-250 Tablet contains Clarithromycin (antibiotic). It inhibits the protein synthesis process required for the growth of the bacterial cell. As a result, bacterial cells are not able to reproduce and grow. Thus, Clarinova-250 Tablet helps prevent infections.

What if I have taken an overdose of Clarinova-250 Tablet

Do not take more than the prescribed dose of Clarinova-250 Tablet as it may cause overdose. The symptoms of overdose include diarrhoea, vomiting, nausea and stomach pain. If you suspect you have taken overdose or notice signs of overdose, please consult a doctor immediately.

Country of origin

India

Manufacturer/Marketer address

208, Okhla Industrial Estate, Phase III, New Delhi - 110020
Other Info - CLA0371

Author Details

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