Cloff 250 Dry Syrup belongs to a group of medicine called macrolide antibiotics derived from Saccharopolyspora erythraea (originally called Streptomyces erythreus), used to treat a wide range of bacterial infections. A bacterial infection is a condition in which bacteria grow in the body and cause infection. It can target any body part and multiple very quickly. Antibiotics inhibit the growth of microorganisms and are given to treat bacterial infections.

Cloff 250 Dry Syrup contains Clarithromycin (antibiotic). It inhibits the protein synthesis process required for the growth of the bacterial cell. As a result, bacterial cells are not able to reproduce and grow. Thus, Cloff 250 Dry Syrup helps in the prevention of infections.

Like all medicines, Cloff 250 Dry Syrup may cause some common side effects, including feeling sick (nausea), diarrhoea and being sick (vomiting), loss of appetite, bloating and indigestion, headaches and difficulty sleeping. Most of these side effects do not require medical attention and gradually resolve over time. However, if you notice any of these side effects persist or worsen your child’s condition, inform your doctor immediately.

Inform your doctor about your child's entire medical history. Other drugs or supplements should not be combined with Cloff 250 Dry Syrup unless prescribed by a doctor. Even if your child is feeling better, do not miss any dose and complete the entire course of medication. Stopping the medication too soon may cause the infection to recur or worsen.

Cloff 250 Dry Syrup belongs to the macrolide class of antibiotics which is effective against a wide range of bacteria, including gram-negative, gram-positive bacteria, anaerobes, and some parasites (like Balantidium coli and Entamoeba species). It is prescribed for treating various bacterial infections, including chest infections such as pneumonia, skin problems such as cellulitis, and ear infections; on the other hand, it is also used in combination with other medicines to treat duodenal ulcers caused by H. pylori (Helicobacter pylori).

• Headache
• Diarrhoea
• Being sick (vomiting)
• Nausea (feeling sick)
• Loss of appetite
• Taste change
• Bloating
• Indigestion
• Abdominal pain
• Insomnia (difficulty sleeping)

Before using Cloff 250 Dry Syrup, let your doctor know about all your children's medical conditions, sensitivities, and all medications used. Do not use any other drugs or supplements with Cloff 250 Dry Syrup unless prescribed by the doctor. Iron and antacid (like magnesium hydroxide and aluminium hydroxide) may bind to Cloff 250 Dry Syrup in the gastrointestinal tract, lowering its efficiency. So, a gap of at least 2 hours should be maintained between intake of Cloff 250 Dry Syrup and iron supplements and antacids.

Drug-Drug Interactions: Cloff 250 Dry Syrup is contraindicated in persons who have shown hypersensitivity to certain antibiotics (e.g. azithromycin, amoxicillin/clavulanate), a statin medicine to lower cholesterol (e.g. simvastatin and atorvastatin), medications used for blood thinners (e.g. warfarin), drugs used for heart problems (e.g. digoxin), certain medicines used for gout (e.g. colchicine), asthma medications (e.g. theophylline, budesonide/formoterol), medicines for epilepsy, (e.g. carbamazepine and phenytoin), and drugs used to treat migraines (e.g. ergotamine and dihydroergotamine).

Drug-Food Interactions: Food containing calcium and iron should be avoided as it may affect Cloff 250 Dry Syrup effectiveness. Also, avoid giving grapefruit or grapefruit juice with Cloff 250 Dry Syrup.

Drug-Disease Interactions: Cloff 250 Dry Syrup should not be given in children with liver or kidney problems, cardiovascular disorders (fast, pounding or irregular heartbeats), QT prolongation, Colitis (a chronic digestive disease characterized by inflammation of the inner lining of the colon), abnormally low levels of potassium in the blood and muscle disease (myasthenia gravis).

• AZITHROMYCIN
• AMOXICILLIN+CLAVULANIC ACID
• SIMVASTATIN
• ATORVASTATIN
• WARFARIN
• DIGOXIN
• COLCHICINE
• THEOPHYLLINE
• BUDESONIDE/FORMOTEROL
• CARBAMAZEPINE
• PHENYTOIN
• ERGOTAMINE
• DIHYDROERGOTAMINE

• It would be best to give probiotics after taking the full course of Cloff 250 Dry Syrup to restore some healthy bacteria in the intestine that may have been killed. Taking probiotics after antibiotic treatment can reduce the risk of antibiotic-associated diarrhoea. Certain fermented foods like yoghurt, cheese, sauerkraut and kimchi can help restore the intestine's good bacteria.
• The BRAT diet (bananas, rice, apple sauce, toast) can help with diarrhoea from antibiotics.
• Give plenty of water to the child. Staying hydrated is important, especially when you’re child sick.
• Eating a broad range of plant-based foods such as vegetables, fruits, nuts, seeds, pulses and wholegrains helps to build a healthy gut microbiome.
• Avoid feeding too many calcium-enriched foods and drinks because they may interfere with the functioning of Cloff 250 Dry Syrup.

Bacterial infections: A bacterial infection is a condition in which harmful bacteria enter, multiply, and infect our body. It can target any body part and multiple very quickly. The symptoms of bacterial infection are fever, chills, and fatigue. Bacteria are of various forms comprising, commonly spherical, rod, and spiral-shaped. Bacterial infections vary from minor illnesses like sore throat and ear infections to severe brain infections like meningitis and encephalitis. A few harmful bacteria that cause infections include Streptococcus, Staphylococcus, and E. coli. Anyone can become infected with a bacterial infection. But, people with weak immune systems or taking immunosuppressive medicine are more prone to get bacterial infections.