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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Synclar 250 mg Mixed Fruit Dry Syrup is used to treat a wide range of bacterial infections. It contains Clarithromycin (antibiotic). It inhibits the protein synthesis process required for bacterial cell growth. As a result, bacterial cells are not able to reproduce and grow. Thus, it helps prevent infections. Common side effects of Synclar 250 mg Mixed Fruit Dry Syrup are feeling sick (nausea), diarrhoea and being sick (vomiting), loss of appetite, bloating and indigestion, headaches and difficulty sleeping.

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Manufacturer/Marketer :

Cipla Ltd

Consume Type :

ORAL

Return Policy :

3 Days Returnable

Expires on or after :

Jan-27

About Synclar 250 mg Mixed Fruit Dry Syrup

Synclar 250 mg Mixed Fruit Dry Syrup belongs to a group of medicine called macrolide antibiotics derived from Saccharopolyspora erythraea (originally called Streptomyces erythreus), used to treat a wide range of bacterial infections. A bacterial infection is a condition in which bacteria grow in the body and cause infection. It can target any body part and multiple very quickly. Antibiotics inhibit the growth of microorganisms and are given to treat bacterial infections.

Synclar 250 mg Mixed Fruit Dry Syrup contains Clarithromycin (antibiotic). It inhibits the protein synthesis process required for the growth of the bacterial cell. As a result, bacterial cells are not able to reproduce and grow. Thus, Synclar 250 mg Mixed Fruit Dry Syrup helps in the prevention of infections.

Like all medicines, Synclar 250 mg Mixed Fruit Dry Syrup may cause some common side effects, including feeling sick (nausea), diarrhoea and being sick (vomiting), loss of appetite, bloating and indigestion, headaches and difficulty sleeping. Most of these side effects do not require medical attention and gradually resolve over time. However, if you notice any of these side effects persist or worsen your child’s condition, inform your doctor immediately.

Inform your doctor about your child's entire medical history. Other drugs or supplements should not be combined with Synclar 250 mg Mixed Fruit Dry Syrup unless prescribed by a doctor. Even if your child is feeling better, do not miss any dose and complete the entire course of medication. Stopping the medication too soon may cause the infection to recur or worsen.

Uses of Synclar 250 mg Mixed Fruit Dry Syrup

Treatment of Bacterial infections

Directions for Use

Oral Suspension: Administer the prescribed dose to the child using the measuring cup/dosing syringe/dropper. Shake the bottle well before use.

Medicinal Benefits

Synclar 250 mg Mixed Fruit Dry Syrup belongs to the macrolide class of antibiotics which is effective against a wide range of bacteria, including gram-negative, gram-positive bacteria, anaerobes, and some parasites (like Balantidium coli and Entamoeba species). It is prescribed for treating various bacterial infections, including chest infections such as pneumonia, skin problems such as cellulitis, and ear infections; on the other hand, it is also used in combination with other medicines to treat duodenal ulcers caused by H. pylori (Helicobacter pylori).

How Synclar 250 mg Mixed Fruit Dry Syrup Works

Synclar 250 mg Mixed Fruit Dry Syrup contains Clarithromycin (antibiotic). It inhibits the protein synthesis process required for the growth of the bacterial cell. As a result, bacterial cells are not able to reproduce and grow. Thus, Synclar 250 mg Mixed Fruit Dry Syrup helps in the prevention of infections.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Synclar 250 mg Mixed Fruit Dry Syrup

  • Headache
  • Diarrhoea
  • Being sick (vomiting)
  • Nausea (feeling sick)
  • Loss of appetite
  • Taste change
  • Bloating
  • Indigestion
  • Abdominal pain
  • Insomnia (difficulty sleeping)

What if I have taken an overdose of Synclar 250 mg Mixed Fruit Dry Syrup

Please do not exceed the recommended dose, as it might cause an overdose. Signs and symptoms of an overdose of Synclar 250 mg Mixed Fruit Dry Syrup may include severe stomach pain, nausea, vomiting, and diarrhea. Seek immediate medical attention if you observe any symptoms or think you have taken too much. Do this even if there are no signs of discomfort or poisoning.

Drug Warnings

Before using Synclar 250 mg Mixed Fruit Dry Syrup, let your doctor know about all your children's medical conditions, sensitivities, and all medications used. Do not use any other drugs or supplements with Synclar 250 mg Mixed Fruit Dry Syrup unless prescribed by the doctor. Iron and antacid (like magnesium hydroxide and aluminium hydroxide) may bind to Synclar 250 mg Mixed Fruit Dry Syrup in the gastrointestinal tract, lowering its efficiency. So, a gap of at least 2 hours should be maintained between intake of Synclar 250 mg Mixed Fruit Dry Syrup and iron supplements and antacids.

Drug-Drug Interactions

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ClarithromycinMesoridazine
Critical
ClarithromycinTolvaptan
Critical

Drug-Drug Interactions

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ClarithromycinMesoridazine
Critical
How does the drug interact with Synclar 250 mg Mixed Fruit Dry Syrup 30 ml:
Co-administration of Synclar 250 mg Mixed Fruit Dry Syrup 30 ml and Mesoridazine may increase the risk of an irregular heart rhythm.

How to manage the interaction:
Co-administration of Synclar 250 mg Mixed Fruit Dry Syrup 30 ml and Mesoridazine can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
ClarithromycinTolvaptan
Critical
How does the drug interact with Synclar 250 mg Mixed Fruit Dry Syrup 30 ml:
When Tolvaptan and Synclar 250 mg Mixed Fruit Dry Syrup 30 ml are taken together, may significantly increase the blood levels and effects of Tolvaptan.

How to manage the interaction:
There may be a possibility of interaction between Tolvaptan and Synclar 250 mg Mixed Fruit Dry Syrup 30 ml, but it can be taken if prescribed by a doctor. If you notice any of these signs -difficulty swallowing, trouble speaking, muscle weakness, trouble controlling body movements, confusion, mood changes, seizures, call a doctor right away. Do not stop using any medications without a doctor's advice.
ClarithromycinDronedarone
Critical
How does the drug interact with Synclar 250 mg Mixed Fruit Dry Syrup 30 ml:
When Dronedarone is taken with Synclar 250 mg Mixed Fruit Dry Syrup 30 ml, can increase the blood levels of dronedarone and cause an irregular heart rhythm that may be serious.

How to manage the interaction:
Taking Synclar 250 mg Mixed Fruit Dry Syrup 30 ml with Dronedarone can result in an interaction, it should be taken only if a doctor has advised it. However, if you experience dizziness, lightheadedness, fainting, shortness of breath, or heart palpitation, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
ClarithromycinNaloxegol
Critical
How does the drug interact with Synclar 250 mg Mixed Fruit Dry Syrup 30 ml:
When Naloxegol is taken with Synclar 250 mg Mixed Fruit Dry Syrup 30 ml, the amount of Naloxegol in the blood can go up.

How to manage the interaction:
Co-administration of Synclar 250 mg Mixed Fruit Dry Syrup 30 ml and Naloxegol can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like sweating, tearing, runny nose, chills, diarrhea, abdominal pain, anxiety, insomnia, irritability, restlessness, and yawning, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
ClarithromycinZiprasidone
Critical
How does the drug interact with Synclar 250 mg Mixed Fruit Dry Syrup 30 ml:
Taking Synclar 250 mg Mixed Fruit Dry Syrup 30 ml with Ziprasidone can increase the risk of irregular heart rhythm.

How to manage the interaction:
Co-administration of Synclar 250 mg Mixed Fruit Dry Syrup 30 ml and Ziprasidone can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
ClarithromycinAstemizole
Critical
How does the drug interact with Synclar 250 mg Mixed Fruit Dry Syrup 30 ml:
When Astemizole is taken with Synclar 250 mg Mixed Fruit Dry Syrup 30 ml, it can cause a decrease in the metabolism of Astemizole.

How to manage the interaction:
Taking Synclar 250 mg Mixed Fruit Dry Syrup 30 ml with Astemizole is not recommended, please consult your doctor before taking it.
ClarithromycinErgotamine
Critical
How does the drug interact with Synclar 250 mg Mixed Fruit Dry Syrup 30 ml:
When Ergotamine is taken with Synclar 250 mg Mixed Fruit Dry Syrup 30 ml, the amount of Ergotamine in the blood can go up.

How to manage the interaction:
Taking Synclar 250 mg Mixed Fruit Dry Syrup 30 ml with Ergotamine can result in an interaction, it should be taken only if a doctor has advised it. However, if you experience abdominal pain, nausea, vomiting, numbness or tingling, muscle pain or weakness, blue or purple discoloration of fingers or toes, pale or cold skin, chest pain or tightness, irregular heartbeat, severe headache, shortness of breath, blurred vision, confusion, and/or slurred speech, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
ClarithromycinColchicine
Critical
How does the drug interact with Synclar 250 mg Mixed Fruit Dry Syrup 30 ml:
Coadministration of colchicine with Synclar 250 mg Mixed Fruit Dry Syrup 30 ml may increase the blood levels of colchicine, increasing the risk of serious side effects.

How to manage the interaction:
Taking Colchicine with Synclar 250 mg Mixed Fruit Dry Syrup 30 ml is not recommended, they can be taken together if advised by your doctor. However, contact your doctor if you experience abdominal pain, nausea, vomiting, diarrhea, fever, muscle pain, weakness, fatigue, and/or numbness or tingling in your hands and feet. Do not stop taking any medications without consulting a doctor.
ClarithromycinQuinidine
Critical
How does the drug interact with Synclar 250 mg Mixed Fruit Dry Syrup 30 ml:
When Quinidine is taken with Synclar 250 mg Mixed Fruit Dry Syrup 30 ml, can increase the blood levels and effects of Quinidine. This may increase the risk of an irregular heart rhythm.

How to manage the interaction:
Co-administration of Synclar 250 mg Mixed Fruit Dry Syrup 30 ml and Quinidine can lead to an interaction, it can be taken if advised by a doctor. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, shortness of breath, or fast or pounding heartbeats. However, if you experience any symptoms like headache, confusion, vomiting, diarrhea, ringing in the ears, hearing loss, blurred or double vision, or sensitivity to light, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
ClarithromycinFlibanserin
Critical
How does the drug interact with Synclar 250 mg Mixed Fruit Dry Syrup 30 ml:
When Flibanserin is taken with Synclar 250 mg Mixed Fruit Dry Syrup 30 ml, it can slow down the way Flibanserin is broken down in the body.

How to manage the interaction:
Co-administration of Synclar 250 mg Mixed Fruit Dry Syrup 30 ml and Flibanserin can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like excessive drowsiness and decreases in blood pressure that can lead to dizziness, lightheadedness, or fainting, consult a doctor immediately. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • It would be best to give probiotics after taking the full course of Synclar 250 mg Mixed Fruit Dry Syrup to restore some healthy bacteria in the intestine that may have been killed. Taking probiotics after antibiotic treatment can reduce the risk of antibiotic-associated diarrhoea. Certain fermented foods like yoghurt, cheese, sauerkraut and kimchi can help restore the intestine's good bacteria.
  • The BRAT diet (bananas, rice, apple sauce, toast) can help with diarrhoea from antibiotics.
  • Give plenty of water to the child. Staying hydrated is important, especially when you’re child sick.
  • Eating a broad range of plant-based foods such as vegetables, fruits, nuts, seeds, pulses and wholegrains helps to build a healthy gut microbiome.
  • Avoid feeding too many calcium-enriched foods and drinks because they may interfere with the functioning of Synclar 250 mg Mixed Fruit Dry Syrup.

Habit Forming

No

Therapeutic Class

ANTI- BACTERIALS

Synclar 250 mg Mixed Fruit Dry Syrup Substitute

Substitutes safety advice
  • Claribid 250 Tablet 10's

    24.08per tablet
  • Clarinova-250 Tablet 10's

    18.63per tablet
  • Cloff 250 Tablet 10's

    by AYUR

    24.08per tablet
  • Claribid 250 DS Combipack Fruit Punch Suspension 30 ml

    by AYUR

    7.49per tablet
  • Clarigard 250 Tablet 10's

    by AYUR

    18.77per tablet
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Alcohol

Not applicable

It is intended for Children.

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Pregnancy

Not applicable

It is intended for Children.

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Breast Feeding

Not applicable

It is intended for Children.

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Driving

Not applicable

It is intended for Children.

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Liver

Caution

Inform your doctor if your child has liver problems. Your doctor will prescribe only if the benefits outweigh the risks.

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Kidney

Caution

Inform your doctor if your child has kidney problems. Your doctor will prescribe only if the benefits outweigh the risks.

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Children

Safe if prescribed

Synclar 250 mg Mixed Fruit Dry Syrup can be given safely to children. Give this medicine to your child in the doses prescribed by the paediatrician.

FAQs

Synclar 250 mg Mixed Fruit Dry Syrup is used to treat Bacterial infections.
Synclar 250 mg Mixed Fruit Dry Syrup contains Clarithromycin (antibiotic). It inhibits the protein synthesis process required for the growth of the bacterial cell. As a result, bacterial cells are not able to reproduce and grow. Thus, Synclar 250 mg Mixed Fruit Dry Syrup helps in the prevention of infections.
After taking antibiotics such as Synclar 250 mg Mixed Fruit Dry Syrup, some people get thrush, a fungal infection. This is due to the fact that antibiotics kill the regular, harmless bacteria that serve to protect you from thrush.
Synclar 250 mg Mixed Fruit Dry Syrup treats only bacterial infections. It will not work for viral infections such as the common cold, or flu.
No, Synclar 250 mg Mixed Fruit Dry Syrup is a macrolide antibiotic. It can be taken by people who are allergic to penicillin with a doctor's advice only.
Side effects are rare with Synclar 250 mg Mixed Fruit Dry Syrup and do not usually last long. They will get better after a day or two. If those side effects persist, reach out to the doctor immediately.

Country of origin

India

Manufacturer/Marketer address

Cipla House, Peninsula Business Park, Ganpatrao Kadam Marg, Lower Parel, Mumbai-400013
Other Info - SYN0298

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